pituitrin and Intestinal-Diseases

Topics: Angiography; Diverticulitis, Colonic; Embolization, Therapeutic; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Intestinal Diseases; Peptic Ulcer Hemorrhage; Vasopressins

Topics: Adult; Clinical Trials as Topic; Contrast Media; Drug Tolerance; Female; Flatulence; Humans; Injections, Intravenous; Intestinal Diseases; Male; Methods; Placebos; Premedication; Urography; Urologic Diseases; Vasopressins; Viscosity

The aim of this study was to investigate the effect of intestinal electrical stimulation on small intestinal dysrhythmia and motion sickness-like symptoms induced by vasopressin. Female dogs chronically implanted with two pairs of electrodes on jejunum serosa were used in a four-session study. Saline and vasopressin were infused in sessions 1 and 2, respectively. Sessions 3 and 4 were the same as session 2, except a long- or short-pulse intestinal electrical stimulation was applied on the proximal pair of electrodes. Intestinal slow waves and motion sickness-like symptoms were recorded in each session. Results were as follows. (1) Vasopressin induced intestinal dysrhythmia, uncoupling of slow waves, and vomiting and motion sickness-like symptoms (P < 0.05, ANOVA). (2) Intestinal electrical stimulation with long pulses, but not short pulses, was capable of preventing vasopressin-induced intestinal dysrhythmia. (3) Intestinal electrical stimulation with short pulses, but not long pulses, prevented vomiting and the motion sickness-like symptoms. It is concluded that vasopressin induces intestinal dysrhythmia. Long-pulse intestinal stimulation normalizes vasopressin-induced intestinal slow-wave abnormalities with no improvement in symptoms. Short-pulse stimulation prevents emetic symptoms induced by vasopressin but has no effect on slow waves. These data suggest different mechanisms involved with different methods of intestinal stimulation.

Topics: Animals; Dogs; Electric Stimulation Therapy; Electrodes, Implanted; Female; Intestinal Diseases; Motion Sickness; Myoelectric Complex, Migrating; Vasoconstrictor Agents; Vasopressins

Topics: Angiography; Catheters, Indwelling; Colonic Diseases; Endoscopy; Esophageal Diseases; Gastrointestinal Hemorrhage; Hemobilia; Humans; Hypertension, Portal; Intestinal Diseases; Peptic Ulcer Hemorrhage; Stomach Diseases; Vasoconstrictor Agents; Vasopressins

Sixty-five sites of arterial gastrointestinal hemorrhage in 63 patients were managed with transcatheter therapy. Arterial vasopressin infusion was attempted primarily for all but three sites; embolization was used in these cases and in those for whom vasopressin infusion failed to control bleeding. The results obtained suggest that this regimen, that is, primary vasopressin infusion with embolization reserved for infusion failures or contraindications, is more effective for control of arterial gastrointestinal hemorrhage than the use of either method alone. The role of primary embolization for control of this type of bleeding may need reassessment.

Topics: Angiography; Arteries; Catheterization; Embolization, Therapeutic; Gastric Mucosa; Gastrointestinal Hemorrhage; Humans; Infusions, Intra-Arterial; Intestinal Diseases; Intestine, Small; Intestines; Pylorus; Stomach; Stomach Diseases; Vasopressins

Topics: Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Humans; Ileum; Infusions, Parenteral; Intestinal Diseases; Ischemia; Jejunum; Mesenteric Arteries; Mesenteric Vascular Occlusion; Middle Aged; Thrombosis; Vasopressins

Topics: Abdomen; Animals; Cecal Diseases; Digestive System; Dogs; Enteritis; Injections, Intravenous; Intestinal Diseases; Jejunum; Radiation Dosage; Radiation Effects; Radiation Injuries, Experimental; Radiation-Protective Agents; Ulcer; Vasopressins

Topics: Catheterization; Esophageal and Gastric Varices; Gangrene; Gastrointestinal Hemorrhage; Hepatic Encephalopathy; Humans; Intestinal Diseases; Male; Mesenteric Arteries; Mesenteric Vascular Occlusion; Middle Aged; Portal Vein; Sepsis; Thrombophlebitis; Thrombosis; Vasopressins

Topics: Animals; Chromatography; Dogs; Gastrointestinal Motility; Humans; Intestinal Absorption; Intestinal Diseases; Pituitary Hormones, Posterior; Vasopressins

Topics: Angiotensin II; Animals; Intestinal Diseases; Ischemia; Norepinephrine; Rats; Shock, Hemorrhagic; Vasopressins

Topics: Angiotensins; Arginine Vasopressin; Endotoxins; Felypressin; Intestinal Diseases; Ischemia; Norepinephrine; Pharmacology; Rats; Research; Shock, Septic; Shock, Traumatic; Vasoconstrictor Agents; Vasopressins