pituitrin and Facial-Injuries

Vasopressin (0.8-1.0 IU), diluted with saline (10 IU vasopressin per 100 ml saline), was selectively injected into the external carotid artery (ECA) to control massive hemorrhage caused by inaccessible serious craniofacial injuries in two patients. This method produced remarkable angiographic vasoconstriction at the involved ECA branches and resulted in immediate hemostasis. Intra-arterial vasopressin injection is a useful option for the treatment of intractable traumatic hemorrhage from inaccessible ECA branches.

Topics: Adult; Carotid Artery Diseases; Carotid Artery, External; Cerebral Angiography; Cerebral Hemorrhage, Traumatic; Facial Injuries; Female; Hemostatics; Humans; Injections, Intra-Arterial; Maxilla; Middle Aged; Occipital Bone; Skull Fractures; Tomography, X-Ray Computed; Vasopressins

A patient is presented with diabetes insipidus secondary to craniofacial trauma. Diabetes insipidus can occur in any patient within ten days of craniofacial trauma. Even the masked disease in the unconscious patient can be diagnosed by observation of intake and output, urinary specific gravities, and appropriate chemical studies. The disease can recur following operative reduction of facial fractures. Diabetes insipidus can be successfully treated by intramuscular Pitressin and appropriate fluid intake.

Topics: Accidents, Traffic; Adolescent; Craniocerebral Trauma; Diabetes Insipidus; Facial Injuries; Humans; Male; Vasopressins

Topics: Adult; Body Water; Brain Injuries; Diabetes Insipidus; Facial Injuries; Female; Fractures, Bone; Humans; Hyponatremia; Hypothalamus; Male; Natriuresis; Osmolar Concentration; Pituitary Gland, Posterior; Prospective Studies; Skull Fractures; Sodium; Vasopressins

Topics: Adult; Diabetes Insipidus; Facial Injuries; Female; Humans; Hyponatremia; Hypothalamo-Hypophyseal System; Kidney Diseases; Male; Natriuresis; Vasopressins; Water Deprivation; Water-Electrolyte Balance