pituitrin and Diabetes--Gestational

To review the etiology, diagnosis, and management of diabetes insipidus during pregnancy.. A search of the literature was performed in PubMed using key word searching and citation snowballing to identify articles published in English between January 1, 1980, and December 31, 2008, on the subject of diabetes insipidus during pregnancy. Once the articles were identified, a thorough review of all results was conducted. Results and conclusions were compiled and summarized.. We reviewed 50 studies selected using the following key words: diabetes insipidus, pregnancy, arginine vasopressin, vasopressinase.. Gestational diabetes insipidus is underdiagnosed because polyuria is often considered normal during pregnancy. Clinicians caring for pregnant women should consider screening for gestational diabetes insipidus, because it could be associated with serious underlying pathology.

Topics: Antidiuretic Agents; Body Water; Deamino Arginine Vasopressin; Diabetes Insipidus; Diabetes, Gestational; Diuretics; Female; Humans; Hydrochlorothiazide; Magnetic Resonance Imaging; Pituitary Gland, Posterior; Pregnancy; Puerperal Disorders; Ultrasonography, Prenatal; Vasopressins

We report a case of transient diabetes insipidus in late pregnancy. This rare condition is characterised by excessive thirst and polyuria and is associated with pre-eclampsia. The aetiology is most likely due to increased vasopressinase activity. Suspected cases should be referred to an obstetric centre, since termination of pregnancy is recommended. The condition normally resolves within a few days of delivery.

Topics: Adult; Cesarean Section; Diabetes Insipidus; Diabetes, Gestational; Female; Humans; Pregnancy; Vasopressins