pituitrin and Cicatrix

To describe resectoscopic treatment with vasopressin injection as an effective surgical intervention for ectopic pregnancy in previous cesarean delivery scar (PCDS) defect.. Case report.. University hospital.. Two women with ectopic pregnancy in PCDS defect.. The patients underwent transvaginal ultrasound examination, followed by operative hysteroscopy with vasopressin injection for evacuating the ectopic pregnancy in PCDS defect.. Conservation of the uterus.. Successful resectoscopic treatment of ectopic pregnancy in PCDS defect.. Resectoscopic treatment of ectopic pregnancy in PCDS defect is a safe and efficient technique that has the advantage of a rapid return to normal levels of β-hCG. Intracervical vasopressin administration could decrease intraoperative bleeding and provide a clear view during the operation.

Topics: Adult; Biomarkers; Blood Loss, Surgical; Cesarean Section; Chorionic Gonadotropin; Cicatrix; Female; Gestational Age; Hemostatics; Humans; Hysteroscopy; Injections; Pregnancy; Pregnancy, Ectopic; Treatment Outcome; Ultrasonography, Prenatal; Vasopressins

Topics: Cesarean Section; Cicatrix; Female; Hemostatics; Humans; Pregnancy; Pregnancy, Ectopic; Vasopressins

Remodelling after myocardial infarction (MI) is associated with vascular adaption, increasing vascular capacity of non-infarcted myocardium, and angiogenesis in the infarcted part during wound healing and scarring. We investigated regional vascular reactivity in the infarcted rat heart. Transmural infarction of the left ventricular free wall was induced by coronary artery ligation. After 3 weeks, regional flow during maximal vasodilation (nitroprusside, NPR) and submaximal vasoconstriction (arginine-vasopressin, AVP) were studied in buffer-perfused hearts. The main findings were: (1) a reduced vasodilator response (NPR) in the viable part of the left ventricular free wall, where hypertrophy was most pronounced, resulting in reduced maximal tissue perfusion of the myocardium bordering the scar (19.7 + 0.6 v 25.7 + 1.2 ml/min.g), whereas perfusion of other non-infarcted regions was preserved. (2) A 54% lower vasodilator response (NPR) and a 25% stronger vasoconstriction (AVP) in scar tissue compared to viable parts of MI hearts. Microscopy showed thicker walls of resistance arteries in scar tissue than in viable parts of MI hearts or in sham hearts, morphometrically substantiated by two- to three-fold greater wall/lumen ratios. These data indicate a deviant response of scar vessels of MI hearts, and in the non-infarcted part, a reduced coronary reserve in the most hypertrophied region. Whereas the former may be caused by different vessel structure, the reduced vasodilator reserve of the spared part of the left ventricular free wall may indicate vasodilation at rest due to insufficient vascular growth. Thus, the most hypertrophied region would be at the highest risk of further ischemic damage.

Topics: Animals; Cicatrix; Coronary Circulation; Coronary Vessels; Heart; Male; Myocardial Infarction; Nitroprusside; Organ Size; Rats; Rats, Wistar; Vasoconstrictor Agents; Vasodilator Agents; Vasopressins

The hypothalamic magnocellular system of the rhesus monkey was studied with specific immunocytochemical techniques in animals that had undergone hypothalamic lesions. The results indicate that this system maintains a regenerative capacity even when its tracts are interrupted within the hypothalamus. New neurohemal units are reconstituted from newly formed vessels within the scar as well as from preexistent blood vessels, such as perforating and pial arterioles, and the vessels of the pars tuberalis of the pituitary gland, which normally do not contain neurosecretory terminals.

Topics: Animals; Brain Diseases; Cicatrix; Female; Fluorescent Antibody Technique; Haplorhini; Hypothalamus; Macaca mulatta; Neurophysins; Oxytocin; Regeneration; Vasopressins