pituitrin and Bronchitis

Topics: Animals; Bronchi; Bronchitis; Calcium; Cilia; Colchicine; Cytochalasin B; Disease Models, Animal; Humans; Mucus; Organ Culture Techniques; Prostaglandins; Proteoglycans; Respiratory Physiological Phenomena; Sputum; Vasopressins

A 66-year-old woman was admitted to our hospital because of vomiting and appetite loss. For the 2 days prior to admission, she had a cold, which had developed into acute viral bronchitis on admission. Because laboratory data on admission showed hyponatremia, intravenous infusion of Ringer's lactate solution was started. However, generalized seizures appeared, and she developed a coma on the day of admission. Her plasma antidiuretic hormone (ADH) level was high in the context of a low serum osmolality on the second hospital day. The infusion rate was increased, and the patient's consciousness level returned to normal. However, her normalized serum Na level declined again as she drank much water to reduce throat discomfort. As the throat discomfort caused by the throat inflammation improved with azulene gargling, her water intake was reduced, and the serum Na concentration returned to normal. Thus, polydipsia caused by a throat inflammation partially contributed to hyponatremia in this patient. We note that increased ADH secretion has been reported in adults with acute respiratory infection. Therefore, we concluded that polydipsia caused by the throat inflammation, plus increased ADH secretion, resulted in hyponatremia in this patient. We should pay attention to the behavior of drinking extra fluid in patients with acute respiratory infections.

Topics: Aged; Bronchitis; Drinking Behavior; Female; Humans; Hyponatremia; Pharyngitis; Seizures; Vasopressins; Water Intoxication

An investigation has been made into various parameters of renal function in patients with chronic bronchitis and in a group of hypoxic controls. Abnormalities of glomerular filtration rate and of water handling have been demostrated in chronic bronchitic patients but not in hypoxic controls. The abnormalities are related to the arterial Pco2. A hypothesis is presented as to the role of CO2 in causing abnormalities of renal function in chronic bronchitis.

Topics: Adult; Aged; Bronchitis; Carbon Dioxide; Edetic Acid; Female; Humans; Hydrocortisone; Hydrogen-Ion Concentration; Kidney; Male; Middle Aged; Oxygen; Vasopressins

Topics: Adrenal Cortex Hormones; Aerosols; Anesthetics, Local; Anti-Bacterial Agents; Antitubercular Agents; Asthma; Bronchitis; Bronchodilator Agents; Catalogs, Drug as Topic; Cresols; Detergents; Drug Prescriptions; Ephedrine; Epinephrine; Germany, East; Humans; Isoproterenol; Mineral Waters; Papaverine; Parasympatholytics; Respiratory Therapy; Respiratory Tract Diseases; Solvents; Sympathomimetics; Terpenes; Theophylline; Tuberculosis, Pulmonary; Vasopressins

Topics: Blood Coagulation; Bronchiectasis; Bronchitis; Capillary Permeability; Diagnosis, Differential; Hemoptysis; Humans; Lung Neoplasms; Menstrual Hygiene Products; Pathology; Pharmacology; Pituitary Hormones, Posterior; Sympathomimetics; Tampons, Surgical; Tracheitis; Tuberculosis; Tuberculosis, Pulmonary; Vasopressins