piroximone has been researched along with Cardiac Failure in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (69.23) | 18.7374 |
| 1990's | 8 (30.77) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bobowski, G; Bristol, JA; Burke, SE; Evans, DB; Newton, RS; Sircar, I; Steffen, RP; Weishaar, RE | 1 |
| Alvarez, R; Bruno, JJ; Stephenson, RA; Strosberg, AM; Venuti, MC | 1 |
| Erhardt, PW | 1 |
| Cohn, JN; Levine, TB; Petein, M | 2 |
| Bussmann, WD; Grohe, G; Klittich, P; Kneissl, GD; Scholz, M; Winkelmann, BW | 1 |
| Baumann, PC; Follath, F; Gallino, A; Ha, HR; Maggiorini, M; Meyer, BJ | 1 |
| Bernadet, P; Besse, P; Coste, P; Dos Santos, P; Durrieu-Jais, C | 1 |
| Castaigne, A; Dubois-Randé, JL; Estagnasie, P; Habbal, R; Lellouche, D; Saal, JP | 1 |
| Albo, C; Benvenuti, C; Castaigne, A; Deleuze, P; Dubois-Randé, JL; Habbal, R; Lellouche, D; Loisance, D; Saal, JP | 1 |
| Thormann, J | 1 |
| Baumann, G; Cremer, G; Joder-Ohlenbusch, AM; Ningel, K; Vieweg, J | 1 |
| Baumann, G; Cremer, G; Ningel, K | 1 |
| Braunwald, E; Colucci, WS; Wright, RF | 1 |
| Burkart, F; Cottier, C; Emmenegger, H; Follath, F; Kiowski, W; Pfisterer, M | 1 |
| Davis, F; Kremser, C; Nemanich, JW; Rajfer, SI; Rossen, JD; Shurman, AJ | 1 |
| Crawford, MH; Kennedy, GT; Miller, WE; O'Rourke, RA; Ruberg, SJ | 1 |
| Hess, ML; Wood, MA | 1 |
| Janicki, JS; Maskin, CS; Weber, KT | 1 |
| Dhainaut, JF | 1 |
| Goto, T; Nunoki, K; Satoh, K; Taira, N | 1 |
| Chatterjee, K; Daly, PA; Kereiakes, D; Modin, G; Simonton, CA | 1 |
| Jain, MC; Janicki, JS; Weber, KT | 1 |
| Axelrod, RJ; Botvinick, EH; Chatterjee, K; Dae, M; De Marco, T | 1 |
| Bache, RJ; Cohn, JN; Heppner, B; Petein, M; Pierpont, GL | 1 |
| Cornyn, J; Loge, D; Massie, BM; Podolin, RA; Topic, N | 1 |
4 review(s) available for piroximone and Cardiac Failure
| Article | Year |
|---|---|
In search of the digitalis replacement.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Cardiotonic Agents; Cyclic AMP; Digitalis Glycosides; Heart Failure; Humans; Myocardial Contraction; Receptors, Adrenergic, beta; Structure-Activity Relationship | 1987 |
New positive inotropic agents in the treatment of congestive heart failure. Mechanisms of action and recent clinical developments. 2.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Administration, Oral; Aminopyridines; Amrinone; Cardiotonic Agents; Coenzymes; Enoximone; Heart; Heart Failure; Hemodynamics; Humans; Imidazoles; Injections, Intravenous; Milrinone; Nifedipine; Oxyfedrine; Phosphodiesterase Inhibitors; Pyridazines; Pyridones; Quinazolines; Ubiquinone | 1986 |
Long-term oral therapy of congestive heart failure with phosphodiesterase inhibitors.
Topics: Administration, Oral; Amrinone; Enoximone; Heart Failure; Humans; Imidazoles; Milrinone; Phosphodiesterase Inhibitors; Pyridones | 1989 |
Effects of new inotropic agents on exercise performance.
Topics: Adrenergic beta-Agonists; Aminopyridines; Amrinone; Cardiac Output; Cardiotonic Agents; Chronic Disease; Enoximone; Heart Failure; Humans; Imidazoles; Milrinone; Muscles; Oxygen; Oxygen Consumption; Physical Exertion; Pulmonary Wedge Pressure; Pyridones; Time Factors | 1986 |
7 trial(s) available for piroximone and Cardiac Failure
| Article | Year |
|---|---|
[Acute hemodynamic effects of piroximone i.v. in patients with severe heart failure].
Topics: Adult; Aged; Cardiac Catheterization; Cardiac Output; Cardiomyopathy, Dilated; Cardiotonic Agents; Coronary Disease; Dose-Response Relationship, Drug; Electrocardiography, Ambulatory; Female; Heart Failure; Hemodynamics; Humans; Imidazoles; Infusions, Intravenous; Male; Middle Aged; Single-Blind Method; Thermodilution | 1995 |
Effects of piroximone on the right ventricular function in severe heart failure patients.
Topics: Adult; Aged; Cardiotonic Agents; Dose-Response Relationship, Drug; Epoprostenol; Female; Heart Failure; Hemodynamics; Humans; Imidazoles; Least-Squares Analysis; Male; Middle Aged; Myocardial Contraction; Phosphodiesterase Inhibitors; Ventricular Function, Right | 1994 |
Additive haemodynamic effects of piroximone and prostacyclin in severe chronic heart failure.
Topics: Adult; Aged; Cardiotonic Agents; Drug Synergism; Drug Therapy, Combination; Epoprostenol; Female; Heart; Heart Failure; Heart Rate; Hemodynamics; Humans; Imidazoles; Male; Middle Aged; Pulmonary Circulation; Vascular Resistance | 1994 |
Piroximone, dobutamine and nitroprusside: comparative effects on haemodynamics in patients with congestive heart failure.
Topics: Adult; Aged; Analysis of Variance; Cardiotonic Agents; Dobutamine; Female; Heart Failure; Hemodynamics; Humans; Imidazoles; Male; Middle Aged; Nitroprusside; Random Allocation | 1991 |
Long-term treatment with piroximone in patients with chronic heart failure.
Topics: Adult; Aged; Analysis of Variance; Arrhythmias, Cardiac; Cardiotonic Agents; Electrocardiography; Exercise; Female; Follow-Up Studies; Heart Failure; Hemodynamics; Humans; Imidazoles; Male; Middle Aged; Multivariate Analysis | 1990 |
Piroximone (MDL 19,205) in the treatment of unstable and stable chronic cardiac failure.
Topics: Administration, Oral; Cardiotonic Agents; Chronic Disease; Clinical Trials as Topic; Exercise Test; Heart Failure; Hemodynamics; Humans; Imidazoles; Infusions, Intravenous; Thermodilution; Time Factors | 1987 |
Persistent hemodynamic effects without long-term clinical benefits in response to oral piroximone (MDL 19,205) in patients with congestive heart failure.
Topics: Administration, Oral; Adult; Aged; Cardiotonic Agents; Clinical Trials as Topic; Female; Heart Failure; Hemodynamics; Humans; Imidazoles; Male; Middle Aged; Norepinephrine; Physical Exertion; Renin; Time Factors | 1986 |
15 other study(ies) available for piroximone and Cardiac Failure
| Article | Year |
|---|---|
Cardiotonic agents. 9. Synthesis and biological evaluation of a series of (E)-4,5-dihydro-6-[2-[4-(1H-imidazol-1-yl)phenyl]ethenyl]-3 (2H)-pyridazinones: a novel class of compounds with positive inotropic, antithrombotic, and vasodilatory activities for t
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cardiotonic Agents; Dogs; Female; Fibrinolytic Agents; Heart Failure; Humans; Imidazoles; Male; Myocardial Contraction; Platelet Aggregation; Pyridazines; Structure-Activity Relationship; Vasodilator Agents | 1989 |
Inhibitors of cyclic AMP phosphodiesterase. 3. Synthesis and biological evaluation of pyrido and imidazolyl analogues of 1,2,3,5-tetrahydro-2-oxoimidazo[2,1-b]quinazoline.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Blood Platelets; Cardiotonic Agents; Dogs; Drug Evaluation; Heart Failure; Humans; Myocardium; Platelet Aggregation; Quinazolines; Structure-Activity Relationship | 1988 |
Hemodynamic effects of a new inotropic agent, piroximone (MDL 19205), in patients with chronic heart failure.
Topics: Adult; Blood Pressure; Dobutamine; Heart Failure; Heart Rate; Hemodynamics; Humans; Imidazoles; Male; Middle Aged; Myocardial Contraction; Pulmonary Artery; Pulmonary Wedge Pressure; Stimulation, Chemical; Vascular Resistance | 1984 |
Hemodynamic effects and concentration-effect relationship of a graded infusion of piroximone in patients with severe heart failure.
Topics: Adult; Aged; Cardiotonic Agents; Dose-Response Relationship, Drug; Heart Failure; Hemodynamics; Humans; Imidazoles; Infusions, Intravenous; Male; Middle Aged; Water-Electrolyte Balance | 1993 |
[Continuous monitoring of cardiac output by analysis of the pulse contour].
Topics: Cardiac Output; Cardiotonic Agents; Female; Heart Failure; Humans; Imidazoles; Male; Middle Aged; Monitoring, Physiologic; Pulse; Systole; Thermodilution; Ventricular Function, Left | 1994 |
The influence of clinical intervention on pressure-volume relationships--the conductance (volume) technique.
Topics: Angioplasty, Balloon, Coronary; Anti-Arrhythmia Agents; Blood Pressure; Cardiac Catheterization; Cardiac Pacing, Artificial; Cardiac Volume; Computer Graphics; Coronary Angiography; Coronary Disease; Enoximone; Heart Failure; Humans; Imidazoles; Myocardial Contraction; Myocardial Ischemia; Phosphodiesterase Inhibitors; Stroke Volume; Ventricular Function, Left | 1992 |
Acute hemodynamic effects of MDL 19205 in mild congestive heart failure.
Topics: Cardiotonic Agents; Heart Failure; Hemodynamics; Humans; Imidazoles; Injections, Intravenous; Male; Myocardial Contraction | 1987 |
Effects of long-term therapy with oral piroximone on resting hemodynamics, peak aerobic capacity, and the anaerobic threshold in patients with heart failure.
Topics: Administration, Oral; Adult; Aerobiosis; Aged; Anaerobiosis; Cardiotonic Agents; Exercise Test; Female; Heart Failure; Hemodynamics; Humans; Imidazoles; Injections, Intravenous; Male; Middle Aged; Time Factors | 1987 |
Hemodynamic effects of a constant intravenous infusion of piroximone in patients with severe congestive heart failure.
Topics: Aged; Cardiotonic Agents; Heart Failure; Hemodynamics; Humans; Imidazoles; Infusions, Intravenous; Male; Middle Aged | 1988 |
[Use of new inotropic agents in the treatment of acute cardiac failure].
Topics: Adrenergic Agonists; Amrinone; Calcium Channel Blockers; Cardiotonic Agents; Dobutamine; Dopamine; Enoximone; Heart Failure; Humans; Imidazoles; Milrinone; Myocardial Contraction; Pyridones | 1988 |
Amelioration of heart failure by MDL 17043 and MDL 19205, novel positive inotropic drugs, in dog heart-lung preparations.
Topics: Animals; Blood Pressure; Cardiac Output; Cardiotonic Agents; Dogs; Dose-Response Relationship, Drug; Enoximone; Female; Heart Conduction System; Heart Failure; Heart Rate; Hemodynamics; Imidazoles; Male | 1985 |
Survival in severe left ventricular failure treated with the new nonglycosidic, nonsympathomimetic oral inotropic agents.
Topics: Administration, Oral; Aged; Anti-Arrhythmia Agents; Cardiotonic Agents; Death, Sudden; Drug Evaluation; Enoximone; Female; Heart Failure; Humans; Imidazoles; Male; Middle Aged; Milrinone; Pyridones; Quinazolines; Retrospective Studies; Time Factors | 1987 |
Hemodynamic and clinical evaluation of piroximone, a new inotrope-vasodilator agent, in severe congestive heart failure.
Topics: Aged; Aged, 80 and over; Cardiotonic Agents; Female; Follow-Up Studies; Heart; Heart Failure; Heart Ventricles; Hemodynamics; Humans; Imidazoles; Male; Middle Aged; Vasodilator Agents | 1987 |
Hemodynamic and regional blood flow response to piroximone (MDL 19,205) in dogs with congestive heart failure: a comparison with dobutamine.
Topics: Animals; Coronary Circulation; Dobutamine; Dogs; Heart Failure; Heart Rate; Hemodynamics; Imidazoles; Regional Blood Flow | 1987 |
Combined hemodynamic and scintigraphic assessment of piroximone (MDL 19,205) and comparison with dobutamine and nitroprusside.
Topics: Adult; Aged; Dobutamine; Drug Administration Schedule; Ferricyanides; Heart Failure; Hemodynamics; Humans; Imidazoles; Male; Middle Aged; Nitroprusside; Radionuclide Imaging | 1987 |