piritrexim has been researched along with Neoplasms in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 5 (55.56) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carducci, M; Huie, M; Izquierda, M; Liu, G; Marnocha, R; Thomas, J; Wilding, G | 1 |
| Marik, PE; Vahid, B | 1 |
| Allegra, CJ; Takimoto, CH | 1 |
| Fleming, GF; Schilsky, RL | 1 |
| Adamson, PC; Arndt, C; Aronson, L; Balis, FM; Clendeninn, NJ; Gillespie, A; Miser, J; Penta, JS; Poplack, DG; Wells, RJ | 1 |
| Benedetto, P; Clendeninn, NJ; Collier, M; Feun, LG; Hanlon, J; Liao, SH; Richman, S; Savaraj, N; Sridhar, KS | 1 |
| Adamson, PC; Balis, FM; Bleyer, WA; Clendeninn, NJ; Gillespie, A; Miser, J; Penta, JS; Poplack, DG; Wells, RJ; Williams, TE | 1 |
| Blum, MR; Clendeninn, NJ; Liao, SH; Sarosy, GA; Shenkenberg, TD; Von Hoff, DD; Weiss, GR; Williams, T; Woolley, JL | 1 |
| Friedlander, ML; Slowiaczek, P; Tattersall, MH; Taylor, IW | 1 |
3 review(s) available for piritrexim and Neoplasms
| Article | Year |
|---|---|
Pulmonary complications of novel antineoplastic agents for solid tumors.
Topics: Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Agents; Bevacizumab; Deoxycytidine; Doxorubicin; Epirubicin; Etoposide; Everolimus; Gemcitabine; Humans; Lung; Lung Diseases; Mitoxantrone; Neoplasms; Pneumonia; Pyrimidines; Risk Factors; Sirolimus; Teniposide; Trastuzumab | 2008 |
New antifolates in clinical development.
Topics: Aminopterin; Antimetabolites, Antineoplastic; Antineoplastic Agents; Drugs, Investigational; Folic Acid Antagonists; Humans; Neoplasms; Pyrimidines; Quinazolines; Thiophenes; Trimetrexate | 1995 |
Antifolates: the next generation.
Topics: Aminopterin; Animals; Antineoplastic Agents; Chemistry, Pharmaceutical; Clinical Trials as Topic; Drug Evaluation; Folic Acid Antagonists; Forecasting; Humans; Neoplasms; Pyrimidines; Quinazolines; Tetrahydrofolates; Thiophenes; Trimetrexate | 1992 |
3 trial(s) available for piritrexim and Neoplasms
| Article | Year |
|---|---|
Phase I study of piritrexim and gemcitabine in patients with advanced solid tumors.
Topics: Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Deoxycytidine; Drug Synergism; Female; Folic Acid Antagonists; Gastrointestinal Diseases; Gemcitabine; Hematologic Diseases; Humans; Kidney; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Pyrimidines; Salvage Therapy; Treatment Outcome | 2005 |
Pediatric phase I trial, pharmacokinetic study, and limited sampling strategy for piritrexim administered on a low-dose, intermittent schedule.
Topics: Adolescent; Adult; Antineoplastic Agents; Brain Neoplasms; Child; Child, Preschool; Drug Administration Schedule; Drug Evaluation; Female; Glioma; Humans; Leukocyte Count; Male; Neoplasms; Platelet Count; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrimidines; Sarcoma | 1992 |
Phase I trial of piritrexim capsules using prolonged, low-dose oral administration for the treatment of advanced malignancies.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Dose-Response Relationship, Drug; Drug Evaluation; Female; Humans; Male; Middle Aged; Neoplasms; Pyrimidines | 1991 |
3 other study(ies) available for piritrexim and Neoplasms
| Article | Year |
|---|---|
Pediatric phase I trial and pharmacokinetic study of piritrexim administered orally on a five-day schedule.
Topics: Adolescent; Adult; Antineoplastic Agents; Child; Drug Evaluation; Half-Life; Humans; Metabolic Clearance Rate; Neoplasms; Pyrimidines | 1990 |
A phase I clinical and pharmacological study of weekly intravenous infusions of piritrexim (BW301U).
Topics: Adult; Aged; Antineoplastic Agents; Drug Administration Schedule; Drug Evaluation; Female; Folic Acid Antagonists; Humans; Infusions, Intravenous; Middle Aged; Neoplasms; Pyrimidines | 1989 |
Selective toxicity of a new lipophilic antifolate, BW301U, for methotrexate-resistant cells with reduced drug uptake.
Topics: Antineoplastic Agents; Cell Line; Drug Resistance; Folic Acid Antagonists; Humans; Methotrexate; Neoplasms; Pyrimethamine; Pyrimidines | 1985 |