piritrexim has been researched along with AIDS-Related Opportunistic Infections in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Devraj, R; Gangjee, A; Queener, SF | 1 |
| Gangjee, A; Queener, SF; Vasudevan, A | 2 |
| Forsch, RA; Queener, SF; Rosowsky, A | 1 |
| Forsch, RA; Inderlied, CB; Queener, SF; Rosowsky, A; Sibley, CH | 1 |
5 other study(ies) available for piritrexim and AIDS-Related Opportunistic Infections
| Article | Year |
|---|---|
Synthesis and dihydrofolate reductase inhibitory activities of 2,4-diamino-5-deaza and 2,4-diamino-5,10-dideaza lipophilic antifolates.
Topics: AIDS-Related Opportunistic Infections; Animals; Folic Acid Antagonists; Liver; Pyrimidines; Rats; Tetrahydrofolate Dehydrogenase; Trimetrexate | 1997 |
Synthesis and biological evaluation of nonclassical 2,4-diamino-5-methylpyrido[2,3-d]pyrimidines with novel side chain substituents as potential inhibitors of dihydrofolate reductases.
Topics: AIDS-Related Opportunistic Infections; Animals; Folic Acid Antagonists; Humans; Liver; Mice; Pneumocystis; Pyrimidines; Rats; Tetrahydrofolate Dehydrogenase; Toxoplasma; Trimetrexate | 1997 |
Conformationally restricted analogues of trimethoprim: 2,6-diamino-8-substituted purines as potential dihydrofolate reductase inhibitors from Pneumocystis carinii and Toxoplasma gondii.
Topics: AIDS-Related Opportunistic Infections; Animals; Binding Sites; Folic Acid Antagonists; Humans; Indicators and Reagents; Kinetics; Liver; Mammals; Molecular Conformation; Pneumocystis; Purines; Pyrimidines; Rats; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Toxoplasma; Trimethoprim | 1997 |
Further studies on 2,4-diamino-5-(2',5'-disubstituted benzyl)pyrimidines as potent and selective inhibitors of dihydrofolate reductases from three major opportunistic pathogens of AIDS.
Topics: AIDS-Related Opportunistic Infections; Animals; Benzyl Compounds; Folic Acid Antagonists; Liver; Magnetic Resonance Spectroscopy; Mycobacterium avium; Pneumocystis; Pyrimidines; Rats; Species Specificity; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Toxoplasma | 2003 |
New 2,4-diamino-5-(2',5'-substituted benzyl)pyrimidines as potential drugs against opportunistic infections of AIDS and other immune disorders. Synthesis and species-dependent antifolate activity.
Topics: AIDS-Related Opportunistic Infections; Animals; Folic Acid Antagonists; Humans; Inhibitory Concentration 50; Liver; Microbial Sensitivity Tests; Mycobacterium avium; Opportunistic Infections; Pneumocystis carinii; Pyrimidines; Rats; Recombinant Proteins; Species Specificity; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Toxoplasma | 2004 |