pirinixic acid has been researched along with Precancerous Conditions in 9 studies
pirinixic acid: structure
Precancerous Conditions: Pathological conditions that tend eventually to become malignant.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hepatocellular adenomas were increased in W-37 (11/20 rats and 0." | 1.29 | Biological potential of basophilic hepatocellular foci and hepatic adenoma induced by the peroxisome proliferator, Wy-14,643. ( Marsman, DS; Popp, JA, 1994) |
| "In ciprofibrate-treated animals 52% and 75% of AA were negative for GST-P and GGT, respectively, and 16% was positive for both the enzymes." | 1.27 | Analysis of peroxisome proliferator-induced preneoplastic and neoplastic lesions of rat liver for placental form of glutathione S-transferase and gamma-glutamyltranspeptidase. ( Ito, N; Rao, MS; Reddy, JK; Subbarao, V; Tatematsu, M, 1986) |
| "Altered areas (AA), neoplastic nodules (NN) and hepatocellular carcinomas (HCC) induced by chronic administration of ciprofibrate and Wy-14,643 were examined for iron accumulation after systemic iron overload." | 1.27 | Increased resistance of peroxisome proliferator-induced hepatic lesions to iron overload in rats. ( Rao, MS; Reddy, JK; Subbarao, V, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Suga, T | 2 |
| Trapp, C | 1 |
| Schwarz, M | 1 |
| Epe, B | 1 |
| Rao, MS | 3 |
| Lalwani, ND | 1 |
| Scarpelli, DG | 1 |
| Reddy, JK | 3 |
| Marsman, DS | 1 |
| Popp, JA | 2 |
| Hanausek, M | 1 |
| Sherman, U | 1 |
| Mirowski, M | 1 |
| Adams, AK | 1 |
| Walaszek, Z | 1 |
| Motoki, Y | 1 |
| Tamura, H | 1 |
| Morita, R | 1 |
| Watanabe, T | 1 |
| Cattley, RC | 1 |
| Tatematsu, M | 1 |
| Subbarao, V | 2 |
| Ito, N | 1 |
1 review available for pirinixic acid and Precancerous Conditions
| Article | Year |
|---|---|
Hepatocarcinogenesis by peroxisome proliferators.
Topics: Administration, Oral; Animals; Gene Expression Regulation, Neoplastic; Hepatocyte Growth Factor; Liv | 2004 |
8 other studies available for pirinixic acid and Precancerous Conditions
| Article | Year |
|---|---|
The peroxisome proliferator WY-14,643 promotes hepatocarcinogenesis caused by endogenously generated oxidative DNA base modifications in repair-deficient Csbm/m/Ogg1-/- mice.
Topics: Animals; Cocarcinogenesis; DNA Damage; DNA Glycosylases; DNA Repair; DNA Repair Enzymes; Guanine; Li | 2007 |
The absence of gamma-glutamyl transpeptidase activity in putative preneoplastic lesions and in hepatocellular carcinomas induced in rats by the hypolipidemic peroxisome proliferator Wy-14,643.
Topics: Acyltransferases; Animals; Anticholesteremic Agents; Hyperplasia; Liver; Liver Neoplasms, Experiment | 1982 |
Biological potential of basophilic hepatocellular foci and hepatic adenoma induced by the peroxisome proliferator, Wy-14,643.
Topics: Adenoma, Liver Cell; Adenosine Triphosphatases; Animals; Carcinogens; Cell Division; Liver; Liver Ne | 1994 |
Induction of a 65-kDa tumor-associated protein in altered hepatic foci of rats fed the peroxisome proliferator Wy-14,643.
Topics: Animals; Gene Expression Regulation; Hyperplasia; Lipofuscin; Liver; Liver Neoplasms, Experimental; | 1994 |
Decreased hepatocyte growth factor level by Wy-14,643, non-genotoxic hepatocarcinogen in F-344 rats.
Topics: Animals; Carcinogens; Hepatocyte Growth Factor; Kidney; Liver Neoplasms, Experimental; Lung; Male; P | 1997 |
Differences between the promoting activities of the peroxisome proliferator WY-14,643 and phenobarbital in rat liver.
Topics: Adenosine Triphosphatases; Animals; Anticholesteremic Agents; Carcinogens; Diethylnitrosamine; gamma | 1989 |
Analysis of peroxisome proliferator-induced preneoplastic and neoplastic lesions of rat liver for placental form of glutathione S-transferase and gamma-glutamyltranspeptidase.
Topics: Animals; Cell Division; Clofibric Acid; Fibric Acids; gamma-Glutamyltransferase; Glutathione Transfe | 1986 |
Increased resistance of peroxisome proliferator-induced hepatic lesions to iron overload in rats.
Topics: Animals; Cell Division; Clofibrate; Clofibric Acid; Fibric Acids; Iron; Liver; Liver Neoplasms, Expe | 1986 |