pirinixic acid has been researched along with Muscular Diseases in 3 studies
pirinixic acid: structure
Muscular Diseases: Acquired, familial, and congenital disorders of SKELETAL MUSCLE and SMOOTH MUSCLE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Due to the adverse effects provoked by hypolipidemic drugs on skeletal muscle function, we also investigated the blocking activity of S-2 and S-4 on skeletal muscle membrane chloride channel conductance and found that these ligands have a pharmacological profile more beneficial compared to fibrates currently used in therapy." | 1.35 | New 2-aryloxy-3-phenyl-propanoic acids as peroxisome proliferator-activated receptors alpha/gamma dual agonists with improved potency and reduced adverse effects on skeletal muscle function. ( Conte Camerino, D; Fracchiolla, G; Laghezza, A; Lavecchia, A; Loiodice, F; Mazza, F; Montanari, R; Novellino, E; Piemontese, L; Pierno, S; Pochetti, G; Tortorella, P, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fracchiolla, G | 1 |
| Laghezza, A | 1 |
| Piemontese, L | 1 |
| Tortorella, P | 1 |
| Mazza, F | 1 |
| Montanari, R | 1 |
| Pochetti, G | 1 |
| Lavecchia, A | 1 |
| Novellino, E | 1 |
| Pierno, S | 1 |
| Conte Camerino, D | 1 |
| Loiodice, F | 1 |
| Faiola, B | 1 |
| Falls, JG | 1 |
| Peterson, RA | 1 |
| Bordelon, NR | 1 |
| Brodie, TA | 1 |
| Cummings, CA | 1 |
| Romach, EH | 1 |
| Miller, RT | 1 |
| Johnson, TE | 1 |
| Zhang, X | 1 |
| Shi, S | 1 |
| Umbenhauer, DR | 1 |
3 other studies available for pirinixic acid and Muscular Diseases
| Article | Year |
|---|---|
New 2-aryloxy-3-phenyl-propanoic acids as peroxisome proliferator-activated receptors alpha/gamma dual agonists with improved potency and reduced adverse effects on skeletal muscle function.
Topics: Animals; Cell Line, Tumor; Chloride Channels; Chlorides; Clofibric Acid; Crystallography, X-Ray; Dru | 2009 |
PPAR alpha, more than PPAR delta, mediates the hepatic and skeletal muscle alterations induced by the PPAR agonist GW0742.
Topics: Animals; Dose-Response Relationship, Drug; Hepatomegaly; Liver; Male; Mice; Mice, Inbred C57BL; Mice | 2008 |
Statins and PPARalpha agonists induce myotoxicity in differentiated rat skeletal muscle cultures but do not exhibit synergy with co-treatment.
Topics: Adenosine Triphosphate; Animals; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Enzy | 2005 |