Page last updated: 2024-11-05

pirinixic acid and Metabolic Syndrome

pirinixic acid has been researched along with Metabolic Syndrome in 2 studies

pirinixic acid: structure

Metabolic Syndrome: A cluster of symptoms that are risk factors for CARDIOVASCULAR DISEASES and TYPE 2 DIABETES MELLITUS. The major components of metabolic syndrome include ABDOMINAL OBESITY; atherogenic DYSLIPIDEMIA; HYPERTENSION; HYPERGLYCEMIA; INSULIN RESISTANCE; a proinflammatory state; and a prothrombotic (THROMBOSIS) state.

Research Excerpts

ExcerptRelevanceReference
" On the basis of these findings and docking pose similarity between telmisartan and rosiglitazone in PPAR gamma active site, two classes of benzimidazole derivatives were designed and synthesized as dual PPAR gamma agonist/angiotensin II antagonists for the possible treatment of metabolic syndrome."3.76Design, synthesis, and docking studies of novel benzimidazoles for the treatment of metabolic syndrome. ( Avery, MA; Carvalho, PB; Chittiboyina, AG; Karamyan, VT; Kurtz, TW; Mizuno, CS; Patny, A; Pershadsingh, HA; Shah, FH; Speth, RC, 2010)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mizuno, CS1
Chittiboyina, AG1
Shah, FH1
Patny, A1
Kurtz, TW1
Pershadsingh, HA1
Speth, RC1
Karamyan, VT1
Carvalho, PB1
Avery, MA1
Larter, CZ1
Yeh, MM1
Van Rooyen, DM1
Brooling, J1
Ghatora, K1
Farrell, GC1

Other Studies

2 other studies available for pirinixic acid and Metabolic Syndrome

ArticleYear
Design, synthesis, and docking studies of novel benzimidazoles for the treatment of metabolic syndrome.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Cell Membrane; Cel

2010
Peroxisome proliferator-activated receptor-α agonist, Wy 14,643, improves metabolic indices, steatosis and ballooning in diabetic mice with non-alcoholic steatohepatitis.
    Journal of gastroenterology and hepatology, 2012, Volume: 27, Issue:2

    Topics: Adipose Tissue; Animals; Blotting, Western; Chemokine CCL2; Diabetes Mellitus; Disease Models, Anima

2012