pirinixic acid has been researched along with Injury, Ischemia-Reperfusion in 7 studies
pirinixic acid: structure
| Excerpt | Relevance | Reference |
|---|---|---|
| " To examine the role of stimulated FAO during ischemia, Etomoxir (Eto), clofibrate, and WY-14,643 compounds were given 5 days prior to the induction of ischemia/reperfusion (I/R) injury." | 3.70 | Etomoxir-induced PPARalpha-modulated enzymes protect during acute renal failure. ( Crew, MD; Dai, G; Gonzalez, FJ; Peters, JM; Portilla, D; Proia, AD, 2000) |
| "Transient cerebral ischemia (30 min), followed by 1-24 h reperfusion, significantly increased the generation of reactive oxygen species, nitric oxide (NO), and lipid peroxidation end-products, as well as markedly reducing levels of the endogenous antioxidant glutathione." | 1.33 | Oxidative stress and inflammatory response evoked by transient cerebral ischemia/reperfusion: effects of the PPAR-alpha agonist WY14643. ( Aragno, M; Benetti, E; Collino, M; Danni, O; Dianzani, C; Fantozzi, R; Gallicchio, M; Mastrocola, R; Thiemermann, C, 2006) |
| "Hepatic ischemia-reperfusion injury is characterized by an intense acute inflammatory response that is dependent on a number of proinflammatory mediators." | 1.32 | Peroxisome proliferator-activated receptor-alpha regulates postischemic liver injury. ( Lentsch, AB; Okaya, T, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (85.71) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, SQ | 1 |
| Li, YH | 1 |
| Hu, SH | 1 |
| Chen, K | 1 |
| Dong, LY | 1 |
| Teoh, NC | 1 |
| Williams, J | 1 |
| Hartley, J | 1 |
| Yu, J | 1 |
| McCuskey, RS | 1 |
| Farrell, GC | 1 |
| Sivarajah, A | 1 |
| Chatterjee, PK | 1 |
| Hattori, Y | 1 |
| Brown, PA | 1 |
| Stewart, KN | 1 |
| Todorovic, Z | 1 |
| Mota-Filipe, H | 1 |
| Thiemermann, C | 2 |
| Okaya, T | 1 |
| Lentsch, AB | 1 |
| Cuzzocrea, S | 1 |
| Di Paola, R | 1 |
| Mazzon, E | 1 |
| Genovese, T | 1 |
| Muià, C | 1 |
| Caputi, AP | 1 |
| Collino, M | 1 |
| Aragno, M | 1 |
| Mastrocola, R | 1 |
| Benetti, E | 1 |
| Gallicchio, M | 1 |
| Dianzani, C | 1 |
| Danni, O | 1 |
| Fantozzi, R | 1 |
| Portilla, D | 1 |
| Dai, G | 1 |
| Peters, JM | 1 |
| Gonzalez, FJ | 1 |
| Crew, MD | 1 |
| Proia, AD | 1 |
7 other studies available for pirinixic acid and Injury, Ischemia-Reperfusion
| Article | Year |
|---|---|
Effects of Wy14643 on hepatic ischemia reperfusion injury in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Disease Models, Animal; Hepatitis; Inter | 2008 |
Short-term therapy with peroxisome proliferation-activator receptor-alpha agonist Wy-14,643 protects murine fatty liver against ischemia-reperfusion injury.
Topics: Animals; Fatty Liver; Mice; Peroxisome Proliferators; Pyrimidines; Reperfusion Injury; Time Factors | 2010 |
Agonists of peroxisome-proliferator activated receptor-alpha (clofibrate and WY14643) reduce renal ischemia/reperfusion injury in the rat.
Topics: Animals; Clofibrate; Gene Expression; Intercellular Adhesion Molecule-1; Kidney; Male; Pyrimidines; | 2002 |
Peroxisome proliferator-activated receptor-alpha regulates postischemic liver injury.
Topics: Animals; Antioxidants; Blotting, Western; Cell Survival; Cells, Cultured; Chemokines; Cytokines; Ele | 2004 |
WY 14643, a potent exogenous PPAR-alpha ligand, reduces intestinal injury associated with splanchnic artery occlusion shock.
Topics: Animals; Blood Pressure; Ileum; Immunohistochemistry; Intercellular Adhesion Molecule-1; Interleukin | 2004 |
Oxidative stress and inflammatory response evoked by transient cerebral ischemia/reperfusion: effects of the PPAR-alpha agonist WY14643.
Topics: Animals; Blotting, Western; Brain Ischemia; Cyclooxygenase 2; Heme Oxygenase (Decyclizing); Hippocam | 2006 |
Etomoxir-induced PPARalpha-modulated enzymes protect during acute renal failure.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Carnitine O-Palmitoyltransferase; Clofibrate; Cre | 2000 |