pirinixic acid has been researched along with Hypertrophy in 4 studies
pirinixic acid: structure
Hypertrophy: General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "By analysis of the data from the Toxicogenomics Database (TG-GATEs), histidine decarboxylase gene (Hdc) was identified as largely and commonly upregulated by three fibrates, clofibrate, fenofibrate, and WY-14,643, which are known to induce hepatocellular hypertrophy and proliferation via stimulation of peroxisome proliferator-activated receptor α (PPARα) in rodents." | 3.96 | Peroxisome proliferator-activated receptor α agonist-induced histidine decarboxylase gene expression in the rat and mouse liver. ( Amagase, Y; Mizukawa, Y; Urushidani, T, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, J | 1 |
| Yang, X | 1 |
| Zhang, YF | 1 |
| Tian, JN | 1 |
| Fan, SC | 1 |
| Gao, Y | 1 |
| Li, HL | 1 |
| Cai, CH | 1 |
| Huang, M | 1 |
| Bi, HC | 1 |
| Amagase, Y | 1 |
| Mizukawa, Y | 1 |
| Urushidani, T | 1 |
| Liang, F | 1 |
| Wang, F | 1 |
| Zhang, S | 1 |
| Gardner, DG | 1 |
| Amacher, DE | 1 |
| Adler, R | 1 |
| Herath, A | 1 |
| Townsend, RR | 1 |
4 other studies available for pirinixic acid and Hypertrophy
| Article | Year |
|---|---|
Peroxisome proliferator-activated receptor α agonist induces mouse hepatomegaly through the spatial hepatocyte enlargement and proliferation.
Topics: Animals; Cell Proliferation; Hepatocytes; Hepatomegaly; Hypertrophy; Liver; Mice; Mice, Knockout; PP | 2023 |
Peroxisome proliferator-activated receptor α agonist-induced histidine decarboxylase gene expression in the rat and mouse liver.
Topics: Animals; Cell Proliferation; Cells, Cultured; Clofibrate; Databases, Genetic; Fenofibrate; Gene Expr | 2020 |
Peroxisome proliferator activated receptor (PPAR)alpha agonists inhibit hypertrophy of neonatal rat cardiac myocytes.
Topics: Animals; Animals, Newborn; Base Sequence; Cell Size; Cells, Cultured; Fenofibrate; Gene Expression; | 2003 |
Use of proteomic methods to identify serum biomarkers associated with rat liver toxicity or hypertrophy.
Topics: 1-Naphthylisothiocyanate; Acetaminophen; Animals; Biomarkers; Chemical and Drug Induced Liver Injury | 2005 |