pirinixic acid has been researched along with Aortic Aneurysm in 1 studies
pirinixic acid: structure
Aortic Aneurysm: An abnormal balloon- or sac-like dilatation in the wall of AORTA.
Excerpt | Relevance | Reference |
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" EXPERIMENTAL APPROACH We determined the effect of LP105, a pirinixic acid derivative which acts as inhibitor of 5-LOX, COX and mPGES-1, on aortic aneurysm development in mice and on 5-LOX activity in murine monocytes." | 7.77 | A pirinixic acid derivative (LP105) inhibits murine 5-lipoxygenase activity and attenuates vascular remodelling in a murine model of aortic aneurysm. ( Brandes, RP; Fischer, AS; Geisslinger, G; Maier, TJ; Mieth, A; Paulke, A; Pellowska, M; Popescu, L; Revermann, M; Schermuly, RT; Schubert-Zsilavecz, M; Steinhilber, D; Steri, R; Wurglics, M, 2011) |
" EXPERIMENTAL APPROACH We determined the effect of LP105, a pirinixic acid derivative which acts as inhibitor of 5-LOX, COX and mPGES-1, on aortic aneurysm development in mice and on 5-LOX activity in murine monocytes." | 3.77 | A pirinixic acid derivative (LP105) inhibits murine 5-lipoxygenase activity and attenuates vascular remodelling in a murine model of aortic aneurysm. ( Brandes, RP; Fischer, AS; Geisslinger, G; Maier, TJ; Mieth, A; Paulke, A; Pellowska, M; Popescu, L; Revermann, M; Schermuly, RT; Schubert-Zsilavecz, M; Steinhilber, D; Steri, R; Wurglics, M, 2011) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Revermann, M | 1 |
Mieth, A | 1 |
Popescu, L | 1 |
Paulke, A | 1 |
Wurglics, M | 1 |
Pellowska, M | 1 |
Fischer, AS | 1 |
Steri, R | 1 |
Maier, TJ | 1 |
Schermuly, RT | 1 |
Geisslinger, G | 1 |
Schubert-Zsilavecz, M | 1 |
Brandes, RP | 1 |
Steinhilber, D | 1 |
1 other study available for pirinixic acid and Aortic Aneurysm
Article | Year |
---|---|
A pirinixic acid derivative (LP105) inhibits murine 5-lipoxygenase activity and attenuates vascular remodelling in a murine model of aortic aneurysm.
Topics: Administration, Oral; Angiotensin II; Animals; Aorta; Aortic Aneurysm; Arachidonate 5-Lipoxygenase; | 2011 |