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pirinixic acid and Aortic Aneurysm

pirinixic acid has been researched along with Aortic Aneurysm in 1 studies

pirinixic acid: structure

Aortic Aneurysm: An abnormal balloon- or sac-like dilatation in the wall of AORTA.

Research Excerpts

ExcerptRelevanceReference
" EXPERIMENTAL APPROACH We determined the effect of LP105, a pirinixic acid derivative which acts as inhibitor of 5-LOX, COX and mPGES-1, on aortic aneurysm development in mice and on 5-LOX activity in murine monocytes."7.77A pirinixic acid derivative (LP105) inhibits murine 5-lipoxygenase activity and attenuates vascular remodelling in a murine model of aortic aneurysm. ( Brandes, RP; Fischer, AS; Geisslinger, G; Maier, TJ; Mieth, A; Paulke, A; Pellowska, M; Popescu, L; Revermann, M; Schermuly, RT; Schubert-Zsilavecz, M; Steinhilber, D; Steri, R; Wurglics, M, 2011)
" EXPERIMENTAL APPROACH We determined the effect of LP105, a pirinixic acid derivative which acts as inhibitor of 5-LOX, COX and mPGES-1, on aortic aneurysm development in mice and on 5-LOX activity in murine monocytes."3.77A pirinixic acid derivative (LP105) inhibits murine 5-lipoxygenase activity and attenuates vascular remodelling in a murine model of aortic aneurysm. ( Brandes, RP; Fischer, AS; Geisslinger, G; Maier, TJ; Mieth, A; Paulke, A; Pellowska, M; Popescu, L; Revermann, M; Schermuly, RT; Schubert-Zsilavecz, M; Steinhilber, D; Steri, R; Wurglics, M, 2011)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Revermann, M1
Mieth, A1
Popescu, L1
Paulke, A1
Wurglics, M1
Pellowska, M1
Fischer, AS1
Steri, R1
Maier, TJ1
Schermuly, RT1
Geisslinger, G1
Schubert-Zsilavecz, M1
Brandes, RP1
Steinhilber, D1

Other Studies

1 other study available for pirinixic acid and Aortic Aneurysm

ArticleYear
A pirinixic acid derivative (LP105) inhibits murine 5-lipoxygenase activity and attenuates vascular remodelling in a murine model of aortic aneurysm.
    British journal of pharmacology, 2011, Volume: 163, Issue:8

    Topics: Administration, Oral; Angiotensin II; Animals; Aorta; Aortic Aneurysm; Arachidonate 5-Lipoxygenase;

2011