piribedil has been researched along with Huntington Disease in 4 studies
Piribedil: A dopamine D2 agonist. It is used in the treatment of parkinson disease, particularly for alleviation of tremor. It has also been used for circulatory disorders and in other applications as a D2 agonist.
Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Meltzer, HY | 1 |
| Majeron, MA | 1 |
| Ambrosoli, C | 1 |
| Armocida, G | 1 |
| Finavera, L | 1 |
| Quisi, Q | 1 |
| Lieberman, AN | 1 |
| Shopsin, B | 1 |
| Brun, YL | 1 |
| Boal, D | 1 |
| Zolfaghari, M | 1 |
| Shoulson, I | 1 |
| Chase, T | 1 |
1 review available for piribedil and Huntington Disease
| Article | Year |
|---|---|
Dopamine autoreceptor stimulation: clinical significance.
Topics: Apomorphine; Dopamine; Haloperidol; Humans; Huntington Disease; Mental Disorders; Neurons; Parkinson | 1982 |
2 trials available for piribedil and Huntington Disease
| Article | Year |
|---|---|
Studies on piribedil in Parkinsonism.
Topics: Adult; Aged; Clinical Trials as Topic; Drug Evaluation; Humans; Huntington Disease; Mental Disorders | 1975 |
Caffeine and the antiparkinsonian response to levodopa or piribedil.
Topics: Adult; Aged; Caffeine; Clinical Trials as Topic; Drug Synergism; Drug Therapy, Combination; Female; | 1975 |
1 other study available for piribedil and Huntington Disease
| Article | Year |
|---|---|
[Attempted direct etiological treatment of Huntington's chorea. Case reports].
Topics: Adult; Aged; Bromocriptine; Drug Therapy, Combination; Female; Haloperidol; Humans; Huntington Disea | 1980 |