pirfenidone has been researched along with Pulmonary Hypertension in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 11 (73.33) | 24.3611 |
| 2020's | 4 (26.67) | 2.80 |
| Authors | Studies |
|---|---|
| Brunetti, ND; Casparrini, M; Correale, M; Foschino Barbaro, MP; Lacedonia, D; Scioscia, G; Simone, F; Stornelli, SR; Tricarico, L | 1 |
| Boulate, D; Crutu, A; Dauriat, G; Dolidon, S; Fabre, D; Fadel, E; Feuillet, S; Florea, V; Gazengel, P; Hanna, A; Le Pavec, J; Mercier, O; Mitilian, D; Mussot, S; Pradere, P | 1 |
| Chu, Y; Liu, E; Ma, X; Qin, W; Yin, Z; Zhang, S; Zhang, Y | 1 |
| Antoniou, K; Behr, J; Bengus, M; Bouros, DE; Gilberg, F; Guiot, J; Harari, S; Kirchgaessler, KU; Kramer, MR; Mogulkoc Bishop, N; Nathan, SD; Perjesi, A; Wells, AU; Wuyts, WA | 1 |
| Elia, D; Harari, S; Humbert, M | 1 |
| Behr, J; Bengus, M; Gilberg, F; Harari, S; Kirchgaessler, KU; Nathan, SD; Wells, AU; Wuyts, W | 1 |
| Homma, S; Kabuki, T; Shibuya, K; Sugino, K | 1 |
| Ask, K; Bellaye, PS; Gauldie, J; Granton, E; Hambly, N; Iglarz, M; Imani, J; Kolb, M; Sato, S; Shimbori, C; Upagupta, C; Yanagihara, T | 1 |
| Bordenave, J; Cumont, A; Dorfmüller, P; Ghigna, MR; Guignabert, C; Huertas, A; Humbert, M; Phan, C; Poble, PB; Quatremare, T; Savale, L; Thuillet, R; Tu, L | 1 |
| Ancochea, J; Bollo, E; Fernández-Fabrellas, E; Franquet, T; Molina-Molina, M; Montero, MA; Serrano-Mollar, A; Xaubet, A | 1 |
| Bergmann, C; Distler, JH | 1 |
| Funke, M; Geiser, T | 1 |
| Hilberg, O | 1 |
| Dejonckheere, F; Maher, TM; Nathan, SD | 1 |
| Acosta, O; Ancochea, J; Bollo, E; Castillo, D; Fernández-Fabrellas, E; Molina-Molina, M; Rodríguez-Portal, JA; Valenzuela, C; Xaubet, A | 1 |
4 review(s) available for pirfenidone and Pulmonary Hypertension
| Article | Year |
|---|---|
Lung transplantation for idiopathic pulmonary fibrosis.
Topics: Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Comorbidity; Disease Progression; Frailty; Gastroesophageal Reflux; Humans; Hypertension, Pulmonary; Idiopathic Interstitial Pneumonias; Idiopathic Pulmonary Fibrosis; Indoles; Lung Neoplasms; Lung Transplantation; Prognosis; Pyridones; Telomere Shortening | 2020 |
Pulmonary Hypertension in Parenchymal Lung Diseases: Any Future for New Therapies?
Topics: Antihypertensive Agents; Chronic Disease; Clinical Trials as Topic; Endothelin Receptor Antagonists; Endpoint Determination; Epoprostenol; Forecasting; Guanylate Cyclase; Humans; Hypertension, Pulmonary; Indoles; Lung Diseases, Interstitial; Phosphodiesterase 5 Inhibitors; Pilot Projects; Protein-Tyrosine Kinases; Pulmonary Disease, Chronic Obstructive; Pyridones | 2018 |
Idiopathic pulmonary fibrosis: the turning point is now!
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Disease Progression; Enzyme Inhibitors; Gastroesophageal Reflux; Humans; Hypertension, Pulmonary; Idiopathic Pulmonary Fibrosis; Indoles; Practice Guidelines as Topic; Pyridones | 2015 |
Survival in Idiopathic Pulmonary Fibrosis: Perspectives from Pulmonary Arterial Hypertension.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Hypertension, Pulmonary; Idiopathic Pulmonary Fibrosis; Indoles; Phosphodiesterase 5 Inhibitors; Pyridones; Survival Rate | 2017 |
2 trial(s) available for pirfenidone and Pulmonary Hypertension
| Article | Year |
|---|---|
Efficacy and safety of sildenafil added to pirfenidone in patients with advanced idiopathic pulmonary fibrosis and risk of pulmonary hypertension: a double-blind, randomised, placebo-controlled, phase 2b trial.
Topics: Aged; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension, Pulmonary; Idiopathic Pulmonary Fibrosis; Male; Pyridones; Sildenafil Citrate | 2021 |
Sildenafil added to pirfenidone in patients with advanced idiopathic pulmonary fibrosis and risk of pulmonary hypertension: A Phase IIb, randomised, double-blind, placebo-controlled study - Rationale and study design.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials, Phase II as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension, Pulmonary; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Multicenter Studies as Topic; Pyridones; Randomized Controlled Trials as Topic; Research Design; Sildenafil Citrate; Vasodilator Agents | 2018 |
9 other study(ies) available for pirfenidone and Pulmonary Hypertension
| Article | Year |
|---|---|
Survival of patients with idiopathic pulmonary fibrosis and pulmonary hypertension under therapy with nintedanib or pirfenidone.
Topics: Humans; Hypertension, Pulmonary; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Treatment Outcome | 2022 |
Pirfenidone Inhibits Hypoxic Pulmonary Hypertension through the NADPH/ROS/p38 Pathway in Adventitial Fibroblasts in the Pulmonary Artery.
Topics: Blotting, Western; Cell Line; Cell Movement; Humans; Hypertension, Pulmonary; NADP; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pulmonary Artery; Pyridones; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction | 2020 |
Systemic scleroderma-related interstitial pneumonia associated with borderline pulmonary arterial hypertension.
Topics: Aged; Anti-Inflammatory Agents; Drug Therapy, Combination; Endothelin A Receptor Antagonists; Female; Humans; Hypertension, Pulmonary; Lung Diseases, Interstitial; Prednisolone; Pulmonary Artery; Pyridones; Pyrimidines; Scleroderma, Limited; Sulfonamides | 2018 |
Macitentan reduces progression of TGF-β1-induced pulmonary fibrosis and pulmonary hypertension.
Topics: Animals; Cell Differentiation; Disease Progression; Female; Humans; Hypertension, Pulmonary; Idiopathic Pulmonary Fibrosis; Lung; Male; Myofibroblasts; Pulmonary Fibrosis; Pyridones; Pyrimidines; Rats; Rats, Sprague-Dawley; Sulfonamides; Transforming Growth Factor beta1 | 2018 |
Therapeutic effect of pirfenidone in the sugen/hypoxia rat model of severe pulmonary hypertension.
Topics: Animals; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Extracellular Matrix; Humans; Hypertension, Pulmonary; Hypoxia; Lung; Male; Muscle, Smooth, Vascular; Pulmonary Artery; Pyridones; Rats; Rats, Wistar; Vascular Remodeling | 2019 |
Guidelines for the diagnosis and treatment of idiopathic pulmonary fibrosis. Sociedad Española de Neumología y Cirugía Torácica (SEPAR) Research Group on Diffuse Pulmonary Diseases.
Topics: Acetylcysteine; Biopsy; Bronchoalveolar Lavage Fluid; Cell- and Tissue-Based Therapy; Clinical Trials as Topic; Contraindications; Diagnostic Imaging; Disease Progression; Evidence-Based Medicine; Gastroesophageal Reflux; Genetic Therapy; Glucocorticoids; Humans; Hypertension, Pulmonary; Idiopathic Pulmonary Fibrosis; Immunologic Factors; Incidence; Indoles; Lung; Lung Transplantation; Oxygen Inhalation Therapy; Palliative Care; Prevalence; Prognosis; Pulmonary Emphysema; Pyridones; Risk Factors; Spain | 2013 |
[Systemic sclerosis - an update].
Topics: Algorithms; Animals; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Endothelin Receptor Antagonists; Guanylate Cyclase; Humans; Hypertension, Pulmonary; Indoles; Pulmonary Artery; Pyrazoles; Pyridones; Pyrimidines; Rituximab; Scleroderma, Systemic; Sulfonamides | 2015 |
IPF, comorbidities and management implications: Patient case 2.
Topics: Arteriosclerosis; Comorbidity; Denmark; Disease Management; Female; Humans; Hypertension, Pulmonary; Idiopathic Pulmonary Fibrosis; Lung Transplantation; Middle Aged; Pyridones; Radiography; Refusal to Treat; Respiratory Function Tests; Severity of Illness Index; Smoking | 2015 |
Guidelines for the medical treatment of idiopathic pulmonary fibrosis.
Topics: Adrenal Cortex Hormones; Disease Progression; Disease-Free Survival; Evidence-Based Medicine; Gastroesophageal Reflux; Gastrointestinal Diseases; Humans; Hypertension, Pulmonary; Idiopathic Pulmonary Fibrosis; Indoles; Meta-Analysis as Topic; Pulmonary Emphysema; Pyridones; Randomized Controlled Trials as Topic; Societies, Medical; Spain | 2017 |