Compounds > pirfenidone
Page last updated: 2024-08-23

pirfenidone and Pancreatic Neoplasms

pirfenidone has been researched along with Pancreatic Neoplasms in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (71.43)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Fan, Z; Li, Z; Liang, J; Liu, Y; Lv, Y; Shen, S; Shen, Y; Wang, L; Xu, G; Zhang, F; Zhang, S; Zhang, Y; Zhao, J; Zhou, S; Zhu, Y; Zou, X1
Bai, Y; Du, L; Gao, F; Jin, L; Li, F; Lin, L; Niu, S; Shi, Q; Sun, T; Wu, J; Zhu, LM1
Caires, HR; Castro, I; Cavadas, B; Ferreira, D; Oliveira, MJ; Pereira, L; Santos, LL; Vasconcelos, MH; Xavier, CPR1
Cai, R; Hao, J; Ji, T; Lang, J; Nie, G; Qi, F; Qin, Z; Wang, J; Wu, W; Zhang, L; Zhang, Y; Zhao, X; Zhao, Y1
Hirokawa, Y; Ishii, K; Kanayama, K; Matsuda, C; Shiraishi, T; Uchida, K; Usugi, E; Watanabe, M1
Ali, SA; Batra, SK; Chakraborty, S; Das, B; Dash, P; Jain, S; Mohanty, AK; Panda, SK; Senapati, S; Suklabaidya, S; Swaminathan, S1
Cui, L; Eguchi, D; Fujiwara, K; Ikenaga, N; Kozono, S; Mizumoto, K; Ohuchida, K; Tanaka, M1

Other Studies

7 other study(ies) available for pirfenidone and Pancreatic Neoplasms

ArticleYear
Pirfenidone-loaded exosomes derived from pancreatic ductal adenocarcinoma cells alleviate fibrosis of premetastatic niches to inhibit liver metastasis.
    Biomaterials science, 2022, Nov-08, Volume: 10, Issue:22

    Topics: Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Exosomes; Humans; Liver Cirrhosis; Liver Neoplasms; Pancreatic Neoplasms

2022
Biodegradable, pH-Sensitive Hollow Mesoporous Organosilica Nanoparticle (HMON) with Controlled Release of Pirfenidone and Ultrasound-Target-Microbubble-Destruction (UTMD) for Pancreatic Cancer Treatment.
    Theranostics, 2019, Volume: 9, Issue:20

    Topics: Animals; Antineoplastic Agents; Cell Line; Cell Line, Tumor; Delayed-Action Preparations; Deoxycytidine; Drug Carriers; Extracellular Matrix; Gemcitabine; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen-Ion Concentration; Immunohistochemistry; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Microbubbles; Nanoparticles; Pancreatic Neoplasms; Pyridones; Silicon Dioxide

2019
Chitinase 3-like-1 and fibronectin in the cargo of extracellular vesicles shed by human macrophages influence pancreatic cancer cellular response to gemcitabine.
    Cancer letters, 2021, 03-31, Volume: 501

    Topics: Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chitinase-3-Like Protein 1; Deoxycytidine; Drug Resistance, Neoplasm; Extracellular Vesicles; Fibronectins; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Macrophages; Pancreatic Neoplasms; Pentoxifylline; Proteomics; Pyridones; Survival Analysis; Up-Regulation

2021
Designing Liposomes To Suppress Extracellular Matrix Expression To Enhance Drug Penetration and Pancreatic Tumor Therapy.
    ACS nano, 2017, 09-26, Volume: 11, Issue:9

    Topics: Animals; Antineoplastic Agents; Deoxycytidine; Extracellular Matrix; Gemcitabine; Humans; Liposomes; Matrix Metalloproteinase 2; Mice, Nude; Pancreatic Neoplasms; Pancreatic Stellate Cells; Peptides; Pyridones; Tumor Cells, Cultured

2017
Antifibrotic Agent Pirfenidone Suppresses Proliferation of Human Pancreatic Cancer Cells by Inducing G0/G1 Cell Cycle Arrest.
    Pharmacology, 2019, Volume: 103, Issue:5-6

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Fibroblasts; Flow Cytometry; G1 Phase Cell Cycle Checkpoints; Humans; Male; Pancreatic Neoplasms; Prostate; Pyridones; Skin; Tumor Microenvironment

2019
Characterization and use of HapT1-derived homologous tumors as a preclinical model to evaluate therapeutic efficacy of drugs against pancreatic tumor desmoplasia.
    Oncotarget, 2016, Jul-05, Volume: 7, Issue:27

    Topics: Acetylcysteine; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Disulfiram; Fibrosis; Guinea Pigs; Humans; Pancreas; Pancreatic Neoplasms; Pancreatic Stellate Cells; Pyridones; Rats; Xenograft Model Antitumor Assays

2016
Pirfenidone inhibits pancreatic cancer desmoplasia by regulating stellate cells.
    Cancer research, 2013, Apr-01, Volume: 73, Issue:7

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Cell Movement; Cell Proliferation; Deoxycytidine; Female; Fibrosis; Gemcitabine; Humans; Immunoenzyme Techniques; Mice; Mice, Inbred BALB C; Mice, Nude; Pancreatic Neoplasms; Pancreatic Stellate Cells; Platelet-Derived Growth Factor; Pyridones; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stromal Cells; Tumor Cells, Cultured

2013