pirfenidone has been researched along with Cryptogenic Fibrosing Alveolitis in 473 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 3 (0.63) | 29.6817 |
2010's | 342 (72.30) | 24.3611 |
2020's | 128 (27.06) | 2.80 |
Authors | Studies |
---|---|
Bast, A; den Hartog, GJM; Gzella, A; Kaminskyy, D; Lelyukh, M; Lesyk, R; Wojtyra, M | 1 |
Liou, JP; Liu, YM; Nepali, K | 1 |
Annoot, D; Auberval, M; Bienvenu, N; Blanque, R; Bock, X; Brys, R; Cherel, L; Christophe, T; Cottereaux, C; Desroy, N; Grassot, JM; Heckmann, B; Housseman, C; Hrvacic, B; Joncour, A; Labeguere, V; Lamers, M; Le Tallec, S; Mollat, P; Monjardet, A; Oste, L; Peixoto, C; Picolet, O; Ralic, J; Roncoroni, V; Rondet, E; Triballeau, N; van der Aar, E; Vandervoort, N; Wakselman, E | 1 |
Chen, X; Du, T; Fu, R; Ji, M; Jin, J; Li, Y; Lin, S; Liu, Y; Sheng, L; Tian, H; Wang, M; Wu, D; Xu, H; Zhang, J; Zhang, K; Zhang, Y | 1 |
Chen, L; Li, Y; Liu, K; Ma, T; Ma, X; Sun, H; Sun, X; Wang, C; Zheng, X; Zhu, Y | 1 |
Huang, MX; Jiang, MY; Le, ML; Luo, HB; Tian, YJ; Wu, Y; Zhang, B; Zhang, C; Zhang, SR | 1 |
Allart, B; Borgonovi, M; Brys, R; Christophe, T; Clément-Lacroix, P; Coornaert, B; Duys, I; El Bkassiny, S; Heckmann, B; Houvenaghel, N; Jans, M; Jaunet, A; Joannesse, C; Mammoliti, O; Menet, C; Oste, L; Palisse, A; Sanière, L; Sonck, K; Wakselman, E | 1 |
Chen, J; Han, C; Huang, MX; Li, Z; Liu, RD; Luo, HB; Tian, YJ; Wu, Y; Xie, X; Yang, YY; Yuan, Y | 1 |
Jiang, Y; Li, N; Li, X; Liang, J; Wang, N; Yang, C; Yang, G; Zhang, K; Zhou, H | 1 |
Kang, J; Song, JW | 1 |
Ishibashi, F; Mizobuchi, T; Nagato, K; Saiki, A; Sugano, I; Tsuyusaki, J | 1 |
Çilli, A; Coşkun, F; Hanta, İ; Ödemiş, A; Sevinç, C; Ursavaş, A | 1 |
Acat, M; Oner, S; Turan, MK; Yildiz Gulhan, P | 1 |
Kreuter, M; Marijic, P; Ruhnke, T; Schwarzkopf, L; Schwettmann, L; Trudzinski, F | 1 |
Aimo, A; Bayes-Genis, A; Emdin, M; Lupón, J; Panichella, G; Spitaleri, G | 1 |
Chambers, DC; Corte, TJ; Cox, IA; de Graaff, B; Glaspole, I; Moodley, Y; Palmer, AJ; Teoh, A; Walters, EH | 1 |
Li, L; Wang, Y; Zang, C; Zheng, Y | 1 |
Anevlavis, S; Archontogeorgis, K; Bonelis, K; Froudarakis, M; Ntolios, P; Paxinou, N; Steiropoulos, P; Voulgaris, A | 1 |
Amselem, S; Bonniaud, P; Cadranel, J; Chevereau, M; Clément, A; Cottin, V; Crestani, B; Dufaure-Garé, I; Gondouin, A; Guéguen, S; Israël-Biet, D; Jouneau, S; Marchand-Adam, S; Nunes, H; Reynaud-Gaubert, M; Wemeau, L | 1 |
Brunetti, ND; Casparrini, M; Correale, M; Foschino Barbaro, MP; Lacedonia, D; Scioscia, G; Simone, F; Stornelli, SR; Tricarico, L | 1 |
Cordova, FC; Criner, GJ; Dorey-Stein, ZL; Galli, JA; Shapiro, W; Zhao, H | 1 |
Chen, F; Huo, J; Li, S; Meng, Y; Tang, Q; Tian, L; Wang, W; Yang, Q | 1 |
Abdelaziz, A; Dutta, P; Finnerty, JP; Kamil, H; Ponnuswamy, A | 1 |
Gil, BM; Heo, JW; Hong, Y; Kang, HS; Kim, YH; Kwon, SS; Lee, EG; Lee, TH; Ryoo, J | 1 |
Liu, X; Qiu, L; Wu, J; Wu, W; Zhang, G | 1 |
Borah, BJ; Dempsey, TM; Limper, AH; Moriarty, JP; Thao, V | 1 |
Hachisu, Y; Hisada, T; Koga, Y; Kouno, S; Maeno, T; Nakagawa, J; Saito, Y; Sawada, Y; Shin, Y; Sunaga, N; Takehara, K; Umetsu, K; Utsugi, M; Wakamatsu, I; Yatomi, M; Yoshimi, S | 1 |
Borsino, C; Mazzoleni, L; Zovi, A | 1 |
Ashish, S; Chanda, D; Chiles, J; Kumar, PL; McDonald, MN; Mobley, JA; Neptune, ER; Thannickal, VJ; Wilson, AC | 1 |
Bastías O, C; Díaz B, I; Reyes C, F; Rodriguez M, K | 1 |
Baart, S; Grutters, JC; Lie, NSL; Miedema, JR; Moor, CC; Mostard, RLM; Veltkamp, M; Wijsenbeek, MS | 1 |
Wells, AU | 2 |
Baba, T; Ikeda, S; Iwasawa, T; Katano, T; Kato, T; Kitamura, H; Oda, T; Ogura, T; Okuda, R; Sekine, A; Shintani, R; Tabata, E; Takemura, T; Yamakawa, H | 1 |
Alonso-Gómez, A; Carrón-Herrero, A; León-Román, F | 1 |
Chiba, H; Kameda, M; Kobayashi, T; Kuronuma, K; Morioka, Y; Otsuka, M; Takahashi, H; Wakabayashi, M; Yoshioka, T | 1 |
Bouzillé, G; Fournier, D; Jouneau, S; Osmont, MN; Polard, E; Scailteux, LM | 1 |
Dušek, L; Gregor, J; Hájková, M; Jovanović, D; Kirchgässler, KU; Kramer, MR; Lewandowska, K; Littnerová, S; Májek, O; Mogulkoć, N; Müller, V; Šterclová, M; Stoeva, N; Studnicka, M; Tekavec-Trkanjec, J; Vašáková, MK | 1 |
Behera, D; Deep, A; Gupta, S; Padhan, P; Priyadarshini, S; Singh, P | 1 |
Cho, YJ; Kim, HJ; Kim, TH; Kim, YW; Kwon, BS; Lee, CT; Lee, JH; Lee, YJ; Lim, SY; Park, JS; Shin, YY; Song, MJ | 1 |
Kang, JH; Kim, DW; Kwon, TK; Park, CW; Yang, MS | 1 |
Belhassen, M; Bonniaud, P; Cottin, V; Dalon, F; Kirchgässler, KU; Nolin, M; Spagnolo, P; Van Ganse, E | 1 |
Ahir, M; Bonnen, MD; Ebrahimpour, A; Eissa, NT; Ghebre, YT; Jegga, AG; Montesi, SB; Raghu, G; Wang, M | 1 |
Caplazi, P; Ding, N; Gierke, S; LaCanna, R; Ma, HY; Moffat, J; N'Diaye, EN; Uttarwar, S; Vander Heiden, JA; Wolters, PJ; Xi, Y | 1 |
Cho, HS; Chung, C; Kim, HC; Kim, J | 1 |
Barczyk, A; Chaudhuri, N; Corte, TJ; Freeman, L; Glaspole, I; Grainge, C; Hopkins, P; Jassem, E; Montgomery, AB; Nair, D; Otto, K; Piotrowski, W; Raghu, G; Shaffer, ML; Šterclová, M; Veale, A; West, A; Wijsenbeek, MS; Wilsher, ML | 1 |
Crooks, JL; Fernández Pérez, ER; Fier, K; Groshong, SD; Humphries, SM; Koelsch, TL; Lynch, DA; Mohning, MP; Solomon, JJ; Swigris, JJ | 1 |
Brown, KK; Costabel, U; Cottin, V; Danoff, SK; Fieuw, A; Ford, P; Groenveld, I; Helmer, E; Jenkins, RG; Jentsch, G; Kreuter, M; Maher, TM; Milner, J; Molenberghs, G; Penninckx, B; Prasad, N; Randall, MJ; Rocak, S; Seghers, I; Shao, L; Taneja, A; Van Den Blink, B; Vandenrijn, C; Verbruggen, N; Watkins, TR; Wijsenbeek, MS; Wuyts, WA | 1 |
Gower, WA; Hagood, JS; McKinzie, CJ; Vece, TJ | 1 |
Cai, H; Cao, M; Gao, Y; Jiang, H; Ma, M; Qiu, X | 1 |
Aliberti, S; Amati, F; Blasi, F; Gramegna, A; Mantero, M; Polelli, V; Stainer, A | 1 |
Gao, H; Gong, B; Gong, T; Huang, Y; Luo, S; Zhang, L; Zhang, R; Zhao, T | 1 |
Albera, C; Alvaro, G; Behr, J; Costabel, U; Gilberg, F; Glassberg, MK; Haller, H; Lancaster, L; Nathan, SD; Samara, K; Wuyts, WA | 1 |
Aguilar-Medina, S; Alva-Lopez, LF; Cazzola, M; Domínguez-Arellano, S; Escobar-Alvarado, JC; Falfán-Valencia, R; Matera, MG; Montiel-Lopez, F; Olaya-López, E; Pérez-Rubio, G; Poo, JL; Ramírez-Venegas, A; Sansores, RH; Zavaleta-Martínez, EO | 1 |
Antoniou, K; Avilés, V; Bachs, A; Bermudo, G; Bonella, F; Maher, TM; Molina-Molina, M; Montes-Worboys, A; Palma, J; Renzoni, E; Rigo-Bonnin, R; Rivera-Ortega, P; Russell, AM; Shull, JG; Suarez-Cuartin, G; Tebé, C; Vancheri, A; Vancheri, C; Vicens-Zygmunt, V; Wijsenbeek, M | 1 |
Jo, YS; Kim, KJ; Kim, YH; Rhee, CK | 1 |
Cao, Y; Zhang, XL; Zheng, B | 1 |
Colquitt, JL; Loveman, E; O'Reilly, K; Scott, DA | 1 |
Chou, W; Glassberg, MK; Lin, CY; Morgenthien, EA; Nathan, SD; Noble, PW; Stauffer, JL | 1 |
Morrow, T | 3 |
Glassberg, MK | 1 |
Bast, A; Drent, M; Elfferich, MDP; Jessurun, NT; Proesmans, VLJ; Wijnen, PAHM | 1 |
Albera, C; Ghirardini, A; Harari, S; Kirchgaessler, KU; Luppi, F; Pesci, A; Rogliani, P; Rottoli, P; Sebastiani, A; Tavanti, L; Tomassetti, S; Vancheri, C | 1 |
Enomoto, N; Fujisawa, T; Furuhashi, K; Hashimoto, D; Hozumi, H; Inui, N; Karayama, M; Kobayashi, T; Kono, M; Koyanagi, Y; Miki, Y; Miyashita, K; Nakamura, H; Nakamura, Y; Saito, G; Suda, T; Suzuki, Y; Tsutsumi, A; Yasui, H | 1 |
Huang, H; Li, S; Shao, C; Sun, YX; Xu, K; Xu, ZJ | 1 |
Chaudhuri, N; Kahn, N; Kreuter, M; Müller, V; Somogyi, V; Torrisi, SE | 1 |
Bocchino, M; Boschetto, P; Casillo, V; Cerri, S; Ciervo, A; Flacco, ME; Luppi, F; Manno, M; Manzoli, L; Stendardo, M | 1 |
Maher, TM; Strek, ME | 1 |
Chen, X; Foda, HD; Hasaneen, NA; Smaldone, GC; Vu, TN | 1 |
Culver, DA; Glennie, J; Li, M; Olman, MA; Perelas, A; Scheraga, RG; van Kerkhove, K | 1 |
Kolb, MR; Wongkarnjana, A; Yanagihara, T | 1 |
Collins, BF; Raghu, G | 1 |
Bartley, K; Bondue, B; Compere, C; Dahlqvist, C; Gusbin, N; Kirchgaessler, KU; Lee, YC; Maddens, S; Schlesser, M; Slabbynck, H; Wuyts, WA | 1 |
Bacchi Reggiani, ML; Bandelli, G; Bassi, I; Betti, S; Carpano, M; Cerri, S; Clini, E; Donatelli, P; Garuti, M; Guerrieri, A; Luppi, F; Monari, M; Nava, S; Tonelli, R | 1 |
Imanishi, N; Kanayama, M; Kuroda, K; Kuwata, T; Matsumiya, H; Mori, M; Shinohara, S; Taira, A; Tanaka, F; Yoneda, K | 1 |
Buendía-Roldan, I; Castillo-Castillo, K; Castillo-Pedroza, J; Estrada, A; Gaxiola, M; Mateos-Toledo, H; Mejía-Ávila, M; Mejía-Hurtado, JG; Rodríguez-Barreto, Ó; Rojas-Serrano, J; Selman, M | 1 |
Beck, S; Bischof, RJ; Davies, AN; Ibrahim, J; Kaminskas, LM; Landersdorfer, CB; Leong, N; Montgomery, AB; Pham, S; Surber, MW | 1 |
Fang, C; Ferianc, M; Guo, J; Huang, H; Xu, Z | 1 |
Chiba, H; Ikeda, K; Kuronuma, K; Mori, Y; Nishikiori, H; Otsuka, M; Takahashi, H; Umeda, Y; Yoshikawa, T | 1 |
Flaherty, KR; Freiheit, EA; Holtze, CH; Kim, HJ; Limb, SL; Pan, WT; Raimundo, K; Stauffer, JL | 1 |
Higo, H; Ichikawa, H; Itano, J; Kajimoto, K; Kanehiro, A; Kayatani, H; Kiura, K; Maeda, Y; Miyahara, N; Oda, N; Senoo, S; Shibayama, T; Taniguchi, A; Tanimoto, Y; Watanabe, H | 1 |
Aokage, K; Ishii, G; Miyoshi, T; Sekihara, K; Tane, K; Tsuboi, M | 1 |
Calvello, M; Cerri, S; Donatelli, P; Iovene, B; Lo Greco, E; Luppi, F; Pavone, M; Richeldi, L; Sgalla, G; Vancheri, A; Vancheri, C; Varone, F | 1 |
Chung, MP; Jegal, Y; Kim, YS; Kim, YW; Lee, HB; Oh, IJ; Park, JS; Park, MS; Song, JW; Uh, ST | 1 |
Bocchino, M; Caminati, A; Faverio, P; Fumagalli, A; Gasbarra, M; Iovino, P; Petruzzi, A; Sanduzzi, A; Scalfi, L; Sebastiani, A; Stanziola, AA | 1 |
Aerts, JGJV; Bresser, P; Chavannes, NH; Grutters, JC; Moor, CC; Mostard, RLM; Wijsenbeek, MS | 1 |
Beers, MF; Duerr, J; Dvornikov, D; Engelmann, TA; Fraumann, SG; Hegermann, J; Herth, FJF; Kawabe, H; Klingmüller, U; Knudsen, L; Konietzke, P; Kreuter, M; Kreutz, C; Leitz, DHW; Mall, MA; Muley, T; Mulugeta, S; Ochs, M; Rotin, D; Seyhan Agircan, A; Szczygiel, M; Wielpütz, MO; Zadora, PK | 1 |
Białas, AJ; Buchczyk, M; Gomółka, P; Górska, K; Jagielska-Len, H; Jarzemska, A; Jassem, E; Jastrzębski, D; Kania, A; Koprowski, M; Krenke, R; Kuś, J; Lewandowska, K; Majewski, S; Martusewicz-Boros, MM; Piotrowski, WJ; Roszkowski-Śliż, K; Siemińska, A; Sobiecka, M; Szewczyk, K; Sładek, K; Tomczak, M; Tomkowski, W; Wiatr, E; Ziora, D; Żołnowska, B | 1 |
Kreuter, M; Luppi, F; Moor, CC; Wuyts, WA | 1 |
Bonella, F; Kreuter, M; Li, X; Oltmanns, U; Peng, S; Shi, H; Wei, L; Yin, D | 1 |
Andrade Cabrera, C; Benites Solis, J; Briones Claudett, KH; Briones Claudett, MH; Grunauer Andrade, M; Rodriguez Garcia, S; Vargas Domenica, E | 1 |
Angibaud, A; Chauvin, P; Diridollou, T; Gaignon, T; Jouneau, S; Kerjouan, M; Lederlin, M; Lemerre, J; Rousseau, C; Salé, A; Sohier, L; Tas, M | 1 |
Kahn, N; Kreuter, M; Torrisi, SE; Vancheri, C | 1 |
Boulate, D; Crutu, A; Dauriat, G; Dolidon, S; Fabre, D; Fadel, E; Feuillet, S; Florea, V; Gazengel, P; Hanna, A; Le Pavec, J; Mercier, O; Mitilian, D; Mussot, S; Pradere, P | 1 |
Franciosa, C; Richeldi, L; Sgalla, G; Simonetti, J | 1 |
Adegunsoye, A; Alqalyoobi, S; Bowman, WS; Haczku, A; Lee, CT; Linderholm, A; Ma, SF; Noth, I; Oldham, JM; Pugashetti, JV; Sarma, N; Sperling, A; Strek, ME | 1 |
Agarwala, P; DeLeon, J; Glass, AD; Glass, DS; Grossfeld, D; Kasselman, LJ; Reiss, AB; Renna, HA; Spiegler, P | 1 |
Chicharro, P; de Argila, D; Muñoz-Aceituno, E; Reolid, A; Rodríguez-Jiménez, P | 1 |
Bonella, F; Maher, TM; Ryerson, CJ; Spagnolo, P; Tzouvelekis, A | 1 |
Fellrath, JM | 1 |
Condos, R; Deshwal, H; Gibson, CD; Kugler, MC; Munger, JS | 1 |
Corral, M; DeYoung, K; Kong, AM | 1 |
Brown, AW; de Andrade, JA; Flaherty, KR; Kaner, RJ; King, CS; Nathan, SD; Noth, I; Padilla, ML; Rahaghi, FF; Safdar, Z; Scholand, MB; Shifren, A | 1 |
Antoniou, K; Kamekis, A; Kokosi, M; Swigris, JJ; Symvoulakis, EK | 1 |
Aerts, JGJV; Bresser, P; Dirksen, CD; Grutters, JC; Kimman, ML; Moor, CC; Mostard, RLM; Wijsenbeek, MS | 1 |
Bando, M; Hattori, N; Homma, S; Inase, N; Johkoh, T; Kataoka, K; Kato, M; Kishaba, T; Kishi, K; Kondoh, Y; Kuwano, K; Mukae, H; Nishioka, Y; Okamoto, M; Saito, T; Sakai, F; Sakamoto, S; Sasaki, S; Suda, T; Taguchi, Y; Takizawa, H; Tanino, Y; Yatera, K | 1 |
Beloki, L; Carruthers, A; Chahboub, A; Clarke, D; Dunmore, R; Güler-Gane, G; Koch, S; Kuziora, M; Lewis, A; Liarte Marin, E; May, R; Miranda, E; Murray, L; Overed-Sayer, C; Parfrey, H; Rassl, D | 1 |
Antoniou, K; Behr, J; Bengus, M; Bouros, DE; Gilberg, F; Guiot, J; Harari, S; Kirchgaessler, KU; Kramer, MR; Mogulkoc Bishop, N; Nathan, SD; Perjesi, A; Wells, AU; Wuyts, WA | 1 |
Apel, RM; Bengel, FM; Derlin, T; Freise, J; Jaeger, B; Jonigk, D; Prasse, A; Ross, TL; Seeliger, B; Shin, HO; Warnecke, G; Weiberg, D; Welte, T; Wester, HJ | 1 |
Broder, MS; Chang, E; Corral, M; Gokhale, S; Reddy, SR | 1 |
Bi, Y; Chen, J; Chowdhury, BA; Karimi-Shah, BA; Marathe, A; Paterniti, MO; Rekić, D; Wang, Y | 1 |
Akazawa, Y; Ishijima, M; Kanazu, M; Kuge, T; Mori, M; Okabe, F; Uenami, T; Yamaguchi, T; Yamamoto, Y; Yano, Y | 1 |
Irfan, M; Trachalaki, A; Wells, AU | 1 |
Arlandis, M; Aznar, T; Chiner, E; Herraiz, P; Marcos Ribes, B; Sancho-Chust, JN; Talens, A | 1 |
Asano, K; Enokida, K; Hattori, S; Hayama, N; Hirabayashi, K; Horio, Y; Ito, Y; Miyaoka, M; Niimi, K; Oguma, T; Ohshinden, K; Takahashi, F; Takahashi, G; Takahashi, M; Takiguchi, H; Takihara, T; Tanaka, J | 1 |
Di Martino, E; Polidori, P; Provenzani, A; Vitulo, P | 1 |
Homma, S; Isobe, K; Isshiki, T; Kurosaki, A; Nakamura, Y; Sakamoto, S; Shimizu, H | 1 |
Agarwal, R; Aggarwal, AN; Bal, A; Behera, D; Dhooria, S; Garg, M; Muth, V; Prasad, KT; Sehgal, IS | 1 |
Barber, CM; Bianchi, SM; Chaudhuri, N; Eaden, JA; Renshaw, SA | 1 |
Azuma, M; Imakura, T; Kagawa, K; Kawano, H; Koyama, K; Murakami, K; Naito, N; Nishimura, H; Nishioka, Y; Sato, S; Shinohara, T; Takahashi, N; Toyoda, Y | 1 |
Dygai, A; Ermakova, N; Krupin, V; Kubatiev, A; Morozov, S; Nebolsin, V; Novikov, F; Pakhomova, A; Pan, E; Pershina, O; Sandrikina, L; Skurikhin, E; Widera, D; Zhukova, M | 1 |
Forbat, E; Parr, D; Shim, TN | 1 |
Ahmad, K; Andrejak, C; Ba, I; Blanchard, E; Bondue, B; Bonniaud, P; Borie, R; Cottin, V; Crestani, B; Froidure, A; Funke-Chambour, M; Gamez, AS; Gondouin, A; Grutters, J; Hirschi, S; Jouneau, S; Justet, A; Kannengiesser, C; Klay, D; Manali, E; Marchand-Adam, S; Molina Molina, M; Naccache, JM; Nunes, H; Papiris, S; Porcher, R; Prévot, G; Reynaud-Gaubert, M; Tromeur, C; van Moorsel, C; Wemeau, L | 1 |
Azuma, A; Chiba, H; Ebina, M; Ikeda, K; Kondoh, Y; Kudoh, S; Miyazawa, S; Nishikiori, H; Nukiwa, T; Ogura, T; Sakaguchi, H; Suga, M; Sugiyama, Y; Taguchi, Y; Takahashi, H | 1 |
Chang, J; Choi, JS; Chung, KS; Jung, JY; Kang, YA; Kim, SY; Kim, YS; Lee, SH; Moon, SW; Park, MS; Song, MJ | 1 |
Aimo, A; Bayes-Genis, A; Egea, OI; Emdin, M | 1 |
Han, H; Huang, Y; Kang, Y; Li, L; Liu, B; Liu, C; Qin, W; Tang, Y; Yuan, X; Zhao, W; Zou, J | 1 |
Dempsey, TM; Limper, AH; Payne, S; Sangaralingham, L; Shah, ND; Yao, X | 1 |
Guler, SA; Lindell, KO; Ryerson, CJ; Swigris, J | 1 |
Baba, T; Hagiwara, E; Ikeda, S; Katano, T; Kitamura, H; Komatsu, S; Misumi, T; Ogura, T; Okabayashi, H; Okuda, R; Sekine, A; Yamakawa, H | 1 |
Ali, MF; Anderson, DK; Aubry, MC; Carmona, EM; Dasari, H; Egan, AM; Kottom, TJ; Limper, AH; Peikert, T; Shaughnessy, GF; Van Keulen, VP; Yi, ES | 1 |
Bodea, C; Cao, S; Karman, J; Levesque, MC; Wang, J | 1 |
Chen, T; Chen, YN; Hu, Y; Huang, Y; Li, HP; Li, QH; Shi, JY; Wang, XD; Weng, D; Wu, CY; Ye, S; Yin, CS; Zhang, AH; Zhang, Y; Zhou, Y | 1 |
Ando, T; Fushimi, K; Hasegawa, W; Jo, T; Matsui, H; Nagase, T; Sakamoto, Y; Uda, K; Urushiyama, H; Yasunaga, H | 1 |
Auriemma, L; Costantini, A; De Vita, F; Di Fabio, C; Di Fabio, L; Esposito, F; Marinari, S; Petragnani, G; Santoleri, F; Spacone, A | 1 |
Comes, A; Richeldi, L; Sgalla, G | 1 |
Khor, YH | 1 |
Chang, J; Jung, JY; Kang, YA; Kim, SY; Kim, YS; Lee, SH; Park, MS; Song, MJ | 1 |
Belhassen, M; Dalon, F; Nolin, M; Van Ganse, E | 1 |
Bando, M; Hara, H; Hashimoto, S; Hisata, S; Homma, S; Inase, N; Izumi, S; Kataoka, K; Kato, M; Mukae, H; Nishioka, Y; Ogura, T; Saito, Y; Sakamoto, S; Shimizu, Y; Tanino, Y; Waseda, Y; Watanabe, K; Yatera, K | 1 |
Lerede, M; Richeldi, L; Sgalla, G | 1 |
Asmani, M; Zhao, R | 1 |
Azuma, A; Ebina, M; Kondoh, Y; Kudoh, S; Miyazawa, S; Nukiwa, T; Ogura, T; Sakaguchi, H; Sakamoto, K; Suga, M; Sugiyama, Y; Suzuki, A; Taguchi, Y; Takahashi, H | 1 |
Lertjitbanjong, P; Moua, T; Petnak, T; Thongprayoon, C | 1 |
Ando, M; Homma, S; Kishi, K; Ono, H; Sugino, K; Tsuboi, E; Watanabe, N | 1 |
Aono, Y; Enomoto, N; Fujisawa, T; Furuhashi, K; Hasegawa, H; Hozumi, H; Inui, N; Karayama, M; Kono, M; Mori, K; Nakamura, H; Nakamura, Y; Naoi, H; Suda, T; Suzuki, Y; Yokomura, K | 1 |
Dempsey, TM; Kelly, BT; Limper, AH; Moua, T; Payne, SR; Sangaralingham, LR; Shah, ND; Teague, TT; Thao, V | 1 |
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Carrington, R; Jordan, S; Page, CP; Pitchford, SC | 1 |
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Kreuter, M; Quaresma, M; Richeldi, L; Stowasser, S; Vancheri, C; Wuyts, WA | 1 |
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Azuma, A; Kashiwada, T | 1 |
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Chen, Q; Huang, W; Ma, Z; Shen, Z; Yu, C; Zhang, H; Zhang, Z; Zhao, C | 1 |
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Buendía-Roldán, I; Mejía, M; Selman, M | 1 |
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Tzouvelekis, A; Wolters, PJ | 1 |
Antoniou, KM; Bibaki, E; Detorakis, S; Margaritopoulos, GA; Papastratigakis, G; Trachalaki, A; Tzanakis, N; Vasarmidi, E; Wells, AU | 1 |
Costabel, U; Glaspole, I; Glassberg, MK; Lancaster, LH; Lederer, DJ; Limb, SL; Morgenthien, EA; Nathan, SD; Pereira, CA; Trzaskoma, B; Wells, AU | 1 |
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Hewitt, RJ; Maher, TM | 1 |
Albera, C; Costabel, U; Gilberg, F; Glassberg, MK; Kirchgaessler, KU; Lancaster, LH; Noble, PW; Petzinger, U; Wuyts, WA | 1 |
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Cilli, A; Hanta, I; Sevinc, C | 1 |
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Bouros, D; Tzilas, V; Tzouvelekis, A | 1 |
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Baba, T; Ikeda, S; Iwasawa, T; Katano, T; Kitamura, H; Oda, T; Ogura, T; Okuda, R; Sadoyama, S; Sekine, A; Shintani, R; Tabata, E; Takemura, T; Yamakawa, H | 1 |
Bajwa, EK; El-Amine, M; Gorina, E; Gupta, R; Kaner, RJ; Lazarus, HM; Luckhardt, TR; Martinez, FJ; Mouded, M; Posada, K; Richeldi, L; Stauffer, J; Tutuncu, A | 1 |
DePew, ZS; Dull, SK; Jagan, N; Malesker, MA; Moore, DR; Morrow, LE | 1 |
Baldi, F; Macagno, F; Panico, L; Pasciuto, G; Richeldi, L | 1 |
Dobashi, K; Hachisu, Y; Hisada, T; Izuhara, K; Kaira, K; Koga, Y; Ohta, S; Ono, J; Tsurumaki, H; Yatomi, M | 1 |
Dempsey, TM; Limper, AH; Sangaralingham, LR; Sanghavi, D; Shah, ND; Yao, X | 1 |
Albera, C; Behr, J; Chou, W; Costabel, U; Kirchgaessler, KU; Limb, SL; Morgenthien, E; Nathan, SD; Noble, PW; Stauffer, JL; Wuyts, WA | 1 |
Albera, C; Gilberg, F; Glassberg, MK; Kirchgaessler, KU; Petzinger, U; Wijsenbeek, MS | 1 |
Ancochea, J; Fernández-Fabrellas, E; Molina-Molina, M; Portal, JAR; Soriano, JB; Valenzuela, C; Xaubet, A | 1 |
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Cha, H; Cho, JM; Kim, HJ; Kim, HR; Kim, YS | 1 |
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Bonella, F; Costabel, U; Wessendorf, TE | 1 |
Jenkins, G | 1 |
Raghu, G; Thickett, DR | 1 |
Cano-Jiménez, E | 1 |
Valenzuela, C | 1 |
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Cottin, V | 4 |
Ancochea, J; Bollo, E; Fernández-Fabrellas, E; Franquet, T; Molina-Molina, M; Montero, MA; Serrano-Mollar, A; Xaubet, A | 1 |
Garber, K | 1 |
Baba, T; Hagiwara, E; Kato, T; Kitamura, H; Ogura, T; Okuda, R | 1 |
Antoniou, KM; Margaritopoulos, GA; Siafakas, NM | 1 |
Katayama, Y; Komada, T; Kusagawa, H; Shomura, S | 1 |
Kanehira, Y; Tada, H; Togami, K | 2 |
Dempsey, OJ; Miller, D | 1 |
Kondoh, Y; Taniguchi, H | 1 |
Homma, S; Ishida, F; Isobe, K; Itoh, T; Muramatsu, Y; Sakamoto, S; Satoh, K; Sugino, K | 1 |
Chaudhuri, N; Duck, A; Frank, R; Holme, J; Leonard, C | 1 |
Ancochea, J; Serrano-Mollar, A; Xaubet, A | 1 |
Clark, P; Landells, LJ; Naidoo, B; Robertson, J | 1 |
Albera, C; Bradford, WZ; Costabel, U; du Bois, RM; King, TE; Leff, JA; Nathan, SD; Noble, PW; Sahn, SA; Valeyre, D | 1 |
Behr, J | 2 |
Poletti, V | 1 |
Kreuter, M | 1 |
Akira, M; Arai, T; Hayashi, S; Inoue, Y; Kitaichi, M; Nakao, K; Okuma, T; Sasaki, Y; Sugimoto, C; Tachibana, K | 1 |
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Hunninghake, GM | 1 |
Bradford, WZ; Castro-Bernardini, S; Fagan, EA; Glaspole, I; Glassberg, MK; Gorina, E; Hopkins, PM; Kardatzke, D; King, TE; Lancaster, L; Lederer, DJ; Nathan, SD; Noble, PW; Pereira, CA; Sahn, SA; Sussman, R; Swigris, JJ | 1 |
Albera, C; Bradford, WZ; Costabel, U; du Bois, RM; King, TE; Leff, JA; Noble, PW; Sahn, SA; Valeyre, D | 1 |
Hoffstein, V; Kardos, P; Kreuter, M | 1 |
Kingwell, K | 1 |
Collard, HR; Ryerson, CJ | 1 |
Ahluwalia, N; Shea, BS; Tager, AM | 1 |
Poletti, V; Ravaglia, C; Tomassetti, S | 1 |
Ehlers-Tenenbaum, S; Herth, FJ; Heussel, CP; Kahn, N; Kreuter, M; Oltmanns, U; Palmowski, K; Puderbach, M; Schnabel, PA; Träger, A; Warth, A; Wenz, H; Wiebel, M | 1 |
Kang, S | 1 |
Covvey, JR; Mancl, EE | 1 |
Albera, C; Bradford, WZ; Costabel, U; du Bois, RM; Hormel, P; King, TE; Noble, PW; Sahn, SA; Valeyre, D | 1 |
Ratner, M | 1 |
Iwata, T; Mizobuchi, T; Nagato, K; Nakajima, T; Nakatani, Y; Ota, S; Suzuki, H; Tagawa, T; Yoshida, S; Yoshino, I | 1 |
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Crooks, MG; Hart, SP | 1 |
Goodwin, A; Jenkins, G | 1 |
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Homma, S; Sakamoto, S; Sugino, K | 1 |
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Spagnolo, P | 2 |
Collard, HR; Spagnolo, P; Wells, AU | 1 |
Bradford, WZ; Collard, HR; du Bois, RM; Ley, B; Vittinghoff, E; Weycker, D | 2 |
Raghu, G; Selman, M | 1 |
Kaminski, N; Rosas, IO | 1 |
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Ahmed, D; Chaudhuri, N; Duck, A; Errhalt, P; Pigram, L | 1 |
Cottin, V; Maher, T | 1 |
Costabel, U | 3 |
Corte, T; King, TE; Moodley, Y; Richeldi, L | 1 |
Einecke, D | 1 |
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Chowdhury, BA; Karimi-Shah, BA | 1 |
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Danoff, SK; Lancaster, LH; Meyer, KC; Nathan, SD | 1 |
King, CS; Nathan, SD | 2 |
Grutters, JC; Wijsenbeek, MS; Wuyts, WA | 1 |
Condos, R; Skaria, SD; Smaldone, GC; Yang, J | 1 |
Hilberg, O | 1 |
Antoniou, K; Costabel, U; Crestani, B; Egan, J; Margaritopoulos, G; Poletti, V; Wells, AU | 1 |
Egan, J | 1 |
Margaritopoulos, G | 1 |
Aravena, C; Arenas, A; Labarca, G; Rada, G; Venegas, C | 1 |
Crestani, B; Porcher, R; Richeldi, L; Thabut, G | 1 |
Caminati, A; Harari, S | 1 |
Behr, J; Kneidinger, N; Milger, K; Neurohr, C; Reichenberger, F | 1 |
Azuma, A; Bando, M; Chida, K; Inoue, Y; Kakutani, S; Kudoh, S; Niimi, Y; Nukiwa, T; Ogura, T; Suga, M; Sugiyama, Y; Taniguchi, H | 1 |
Kremer, MR; Wand, O | 1 |
Bonella, F; Maher, TM; Spagnolo, P | 1 |
Prasse, A | 1 |
Elmufdi, F; Henke, CA; Kim, HJ; Perlman, DM; Tomic, R | 1 |
Chen, BY; Dai, HP; Huang, H; Kang, J; Sun, TY; Xu, ZJ | 1 |
George, G; Summer, R; Vaid, U | 1 |
Azuma, A; Ebina, M; Kondoh, Y; Kudoh, S; Nakata, K; Nukiwa, T; Ogura, T; Suga, M; Sugiyama, Y; Taguchi, Y; Takahashi, H; Taniguchi, H | 1 |
Azuma, A; Ebina, M; Hashimoto, S; Kondoh, Y; Kudoh, S; Nakata, K; Nukiwa, T; Ogura, T; Suga, M; Sugiyama, Y; Taguchi, Y; Takahashi, H; Taniguchi, H | 1 |
Bianchini, E; Bocchino, M; Carbonelli, CM; Cerri, S; Cossarizza, A; De Biasi, S; Gibellini, L; Luppi, F; Montanari, G; Persiani, E; Richeldi, L; Sgalla, G; Vancheri, C; Zamparelli, AS; Zucchi, L | 1 |
Belloli, EA; Flaherty, KR; Martinez, FJ | 1 |
Noble, PW; Selvaggio, AS | 1 |
Arita, M; Fukuda, Y; Hashimoto, T; Ishida, T; Ito, A; Ito, I; Iwasaku, M; Konishi, S; Kourogi, Y; Kunimasa, K; Masuda, G; Nishiyama, A; Tachibana, H; Takaiwa, T; Tanaka, M; Tokioka, F; Tsubouchi, K; Watanabe, N; Yoshioka, H | 1 |
Albera, C; Bradford, WZ; Costabel, U; du Bois, RM; Fagan, EA; Fishman, RS; Glaspole, I; Glassberg, MK; King, TE; Lancaster, L; Lederer, DJ; Leff, JA; Nathan, SD; Noble, PW; Pereira, CA; Swigris, JJ; Valeyre, D | 1 |
Munakata, M | 1 |
Locy, ML; Luckhardt, TR; Rangarajan, S; Thannickal, VJ | 1 |
Ripamonti, E; Russell, AM; Vancheri, C | 1 |
Bonella, F; Kreuter, M; Maher, TM; Spagnolo, P; Wijsenbeek, M | 1 |
Morrow, TJ | 1 |
Fraser, E; Hoyles, RK | 1 |
Canestaro, WJ; Devine, BE; Forrester, SH; Ho, L; Raghu, G | 1 |
Beyene, J; Brozek, J; Garcia, CC; Neupane, B; Raghu, G; Richeldi, L; Rochwerg, B; Schünemann, H; Zhang, Y | 1 |
Kaarteenaho, R; Karvonen, H; Korpela, S; Lappi-Blanco, E; Lehtonen, ST; Sköld, MC; Sormunen, R; Veijola, A; Zagai, U | 1 |
Funke-Chambour, M; Geiser, T | 1 |
Azuma, A; Bando, M; Homma, S; Ogura, T; Sugiyama, Y; Taniguchi, H; Watanabe, K; Yamauchi, H | 1 |
Fukuda, Y; Goto, H; Hanibuchi, M; Morizumi, S; Nishioka, Y; Sato, S; Takahashi, M; Toyoda, Y | 1 |
Baba, T; Ikeda, S; Kitamura, H; Morita, M; Ogura, T; Sekine, A; Yamakawa, H | 1 |
Albera, C; Bradford, WZ; Costabel, U; du Bois, RM; Fagan, EA; Fishman, RS; Glaspole, I; Glassberg, MK; Glasscock, KF; King, TE; Lancaster, L; Lederer, DJ; Lin, Z; Nathan, SD; Noble, PW; Pereira, CA; Swigris, JJ; Valeyre, D; Wells, AU | 1 |
Hanada, S; Kishi, K; Kurosaki, A; Miyamoto, A; Mochizuki, S; Morokawa, N; Murase, K; Ogawa, K; Takahashi, Y; Takaya, H; Takeyasu, M; Uruga, H | 1 |
Costabel, U; Herth, FJ; Kirchgaessler, KU; Kolb, M; Koschel, D; Kreuter, M; Maher, TM; Renzoni, E; Spagnolo, P; Weycker, D; Wuyts, W | 1 |
Beltramo, G; Borie, R; Crestani, B; Justet, A; Manali, ED; Pradère, P; Spagnolo, P | 1 |
Hagmeyer, L; Priegnitz, C; Randerath, WJ; Treml, M | 1 |
Corte, TJ; Jo, HE; Moodley, Y; Randhawa, S | 1 |
Bacon, KB; Boehme, SA; DiTirro, DN; Franz-Bacon, K; Ly, TW | 1 |
Albera, C; Beck, J; Behr, J; Bendstrup, E; Crestani, B; Günther, A; Koschel, D; Kreuter, M; Lin, CY; Olschewski, H; Sköld, CM; Wallaert, B; Wells, A; Wuyts, W | 1 |
Anderson, A; Nathan, SD; Shifren, A | 1 |
Bondue, B; Corhay, JL; Guiot, J; Henket, M; Louis, R | 1 |
Matěj, R; Vašáková, M | 1 |
Jones, MG; Richeldi, L | 1 |
Balìa, C; Celi, A; Faìta, F; Lombardi, S; Neri, T; Paggiaro, P; Pedrinelli, R; Petrini, S; Scalise, V | 1 |
Adams, TN; Battaile, JT; Eiswirth, C; Newton, CA | 1 |
Brown, KK | 1 |
Calandriello, L; Dubini, A; Farchione, A; Franchi, P; Larici, AR; Mastrobattista, A; Poletti, V; Tagliaboschi, L; Tomassetti, S; Varone, F; Viglietta, L | 1 |
Gomez, DC; Mehrad, B | 1 |
Asato, Y; Azuma, A; Chida, M; Fukuoka, J; Hiroshima, K; Ikeda, N; Iwasawa, T; Iwata, T; Katakami, N; Kuwano, K; Matsuura, M; Mitsudomi, T; Nakagawa, K; Nakanishi, Y; Okada, M; Okami, J; Okubo, K; Sakai, S; Sakamoto, K; Tada, H; Takenoyama, M; Tomii, K; Tsuboi, M; Yamashita, M; Yamashita, Y; Yokouchi, H; Yoshida, S; Yoshimura, K; Yoshino, I | 1 |
Albera, C; Costabel, U; Fagan, EA; Glassberg, MK; Gorina, E; Lancaster, L; Lederer, DJ; Nathan, SD; Spirig, D; Swigris, JJ | 1 |
Calzetta, L; Cavalli, F; Cazzola, M; Matera, MG; Rogliani, P | 1 |
Chilvers, ER; Fiddler, CA; Miremadi, A; Parfrey, H; Simler, N | 1 |
Adegunsoye, A; Strek, ME | 1 |
Fletcher, S; Jones, MG; Limbrey, R; Marshall, BG; Richeldi, L; Sgalla, G; Spinks, K | 1 |
Fujiwara, T; Iwata, T; Nakajima, T; Suzuki, H; Wada, H; Yoshida, S; Yoshino, I | 1 |
Abel, PW; Casale, TB; Jiang, H; Mehrotra, S; Panettieri, RA; Rennard, S; Toews, ML; Tu, Y; Wolff, DW; Xie, Y; Zhang, Q | 1 |
Bando, M | 1 |
Robinson, HC | 1 |
Clarke, DL; Crestani, B; Murray, LA; Sleeman, MA | 1 |
Bonella, F; Costabel, U; Kirchgaessler, KU; Kolb, M; Kreuter, M; Maher, TM; Spagnolo, P; Weycker, D | 1 |
Biju, G; Jyothi, E; Kumar, NK; Narayan, KV; Suraj, KP | 1 |
Hosein, K; Le, J; Mura, M | 1 |
Altraja, A; Bendstrup, E; Ferrara, G; Gudmundsson, G; Hilberg, O; Kaarteenaho, R; Myllärniemi, M; Sjåheim, T; Sköld, CM | 1 |
Delanote, I; Verbeken, EK; Verleden, GM; Vos, R; Wuyts, WA; Yserbyt, J | 1 |
Albera, C; Bradford, WZ; Costabel, U; Daigl, M; Glaspole, I; Glassberg, MK; Kardatzke, DR; Kirchgaessler, KU; Lancaster, LH; Lederer, DJ; Nathan, SD; Noble, PW; Pereira, CA; Swigris, JJ; Valeyre, D | 1 |
Guo, F; Song, X; Yu, W | 1 |
Bayly, S; Brown, KK; Chien, JW; Collard, HR; Cottin, V; Gibson, KF; Gong, Q; Kaner, RJ; Lederer, DJ; Martinez, FJ; Moreau, E; Noble, PW; O'Riordan, TG; Patterson, SD; Raghu, G; Smith, V; Song, JW; Wells, AU; Whelan, TP; Wuyts, W; Zhang, JJ | 1 |
Akasaki, T; Hamada, M; Hara, M; Ise, S; Ishimoto, H; Ishizu, M; Izumi, M; Kawabata, M; Kawasaki, M; Koreeda, Y; Kumazoe, H; Maki, S; Mukae, H; Nagata, N; Oda, K; Takakura, K; Takata, S; Wakamatsu, K; Yoshimi, M | 1 |
Chang, S; Diamantopoulos, A; Esser, D; LeReun, C; Maher, TM; Rinciog, C; Watkins, M | 1 |
Jeldres, A; Labarca, G | 1 |
Antony, VB; Bae, S; de Andrade, J; Li, FJ; Li, H; Liu, G; Liu, RM; Luckhardt, T; Rangarajan, S; Surolia, R; Thannickal, VJ; Wang, Z; Zhou, Y | 1 |
Didiasova, M; Kwapiszewska, G; Lauth, M; Markart, P; Schaefer, L; Seeger, W; Singh, R; Wilhelm, J; Wujak, L; Wygrecka, M; Zakrzewicz, D | 1 |
Aichler, M; Bächinger, HP; Behr, J; Eickelberg, O; Hatz, R; Heinzelmann, K; Ishikawa, Y; Knüppel, L; Staab-Weijnitz, CA; Walch, A | 1 |
Aiello, M; Bertorelli, G; Bocchino, M; Chetta, A; Fiore-Donati, A; Fois, A; Marinari, S; Oggionni, T; Polla, B; Rosi, E; Sanduzzi, A; Stanziola, A; Varone, F | 1 |
Kim, BS; Kim, GW; Kim, HS; Kim, JM; Kim, MB; Ko, HC; Park, MY; Shim, WH | 1 |
George, PM; Wells, AU | 1 |
Collard, HR | 2 |
Daigl, M; Edwards, SC; Fisher, M; Fleetwood, K; Glanville, J; Gsteiger, S; McCool, R | 1 |
Dejonckheere, F; Fisher, M; Hill, C; Maher, TM; Marshall, J; Nathan, SD; Thuresson, PO | 1 |
Dejonckheere, F; Maher, TM; Nathan, SD | 1 |
Acosta, O; Ancochea, J; Bollo, E; Castillo, D; Fernández-Fabrellas, E; Molina-Molina, M; Rodríguez-Portal, JA; Valenzuela, C; Xaubet, A | 1 |
Hasegawa, T; Tango, T | 1 |
Wang, ZL | 1 |
Oku, H; Tokura, T; Tsukamoto, Y | 1 |
Azuma, A; Ebina, M; Kondoh, Y; Kudoh, S; Nakata, K; Nukiwa, T; Ogura, T; Raghu, G; Sato, A; Suga, M; Taguchi, Y; Takahashi, H; Takeuchi, M; Taniguchi, H | 1 |
Azuma, A | 2 |
Fairclough, D; Swigris, J | 1 |
Bouros, D | 1 |
Albera, C; Bradford, WZ; Costabel, U; du Bois, RM; Glassberg, MK; Kardatzke, D; King, TE; Lancaster, L; Noble, PW; Sahn, SA; Szwarcberg, J; Valeyre, D | 1 |
Azuma, A; Ebina, M; Kondoh, Y; Kudoh, S; Nakata, K; Nukiwa, T; Ogura, T; Sato, A; Suga, M; Sugiyama, Y; Taguchi, Y; Takahashi, H; Taniguchi, H | 1 |
Kirkpatrick, P; Richeldi, L; Yasothan, U | 1 |
du Bois, RM; Richeldi, L | 1 |
Carter, NJ | 1 |
Azuma, A; Ebina, M; Kondoh, Y; Kudoh, S; Nakata, K; Nukiwa, T; Ogura, T; Sato, A; Suga, M; Taguchi, Y; Takahashi, H; Taniguchi, H | 1 |
Baba, T; Gotoh, T; Inoue, T; Iwasawa, T; Kanauchi, T; Komagata, T; Morita, S; Ogura, T; Sakai, F; Yazawa, T | 1 |
Günther, A; Korfei, M; Mahavadi, P; Markart, P; Ruppert, C; von der Beck, D | 1 |
Richeldi, L | 2 |
Bendstrup, E; du Bois, R; Hilberg, O; Simonsen, U | 1 |
Cerri, S; Luppi, F; Richeldi, L; Spagnolo, P | 1 |
Kagouridis, K; Kolilekas, L; Manali, ED; Papiris, SA; Triantafillidou, C; Tsangaris, I | 1 |
Adamali, HI; Maher, TM | 1 |
Behr, J; Hoeper, MM; Klotsche, J; Kreuter, M; Pittrow, D; Wirtz, H | 1 |
132 review(s) available for pirfenidone and Cryptogenic Fibrosing Alveolitis
Article | Year |
---|---|
Idiopathic Pulmonary Fibrosis: Current Status, Recent Progress, and Emerging Targets.
Topics: Animals; Anti-Inflammatory Agents; Anticoagulants; Antioxidants; Apoptosis; Humans; Idiopathic Pulmonary Fibrosis; Indoles; NADPH Oxidase 1; NADPH Oxidase 4; NADPH Oxidases; Patents as Topic; Protein Kinase Inhibitors; Pyridones; Receptors, Lysophosphatidic Acid | 2017 |
Pirfenidone as a novel cardiac protective treatment.
Topics: Animals; Fibrosis; Humans; Idiopathic Pulmonary Fibrosis; Myocytes, Cardiac; Pyridones | 2022 |
The effects and safety of pirfenidone in the treatment of idiopathic pulmonary fibrosis: a meta-analysis and systematic review.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diarrhea; Exanthema; Humans; Idiopathic Pulmonary Fibrosis; Lung; Nausea; Progression-Free Survival; Pyridones; Treatment Outcome; Vital Capacity | 2021 |
Efficacy of antifibrotic drugs, nintedanib and pirfenidone, in treatment of progressive pulmonary fibrosis in both idiopathic pulmonary fibrosis (IPF) and non-IPF: a systematic review and meta-analysis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antifibrotic Agents; Cause of Death; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pulmonary Fibrosis; Pyridones; Treatment Outcome | 2021 |
Efficacy and safety of pirfenidone in the treatment of idiopathic pulmonary fibrosis patients: a systematic review and meta-analysis of randomised controlled trials.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Pulmonary Fibrosis; Lung Diseases, Interstitial; Progression-Free Survival; Pyridones; Randomized Controlled Trials as Topic; Treatment Outcome; Vital Capacity | 2021 |
Efficacy of Pirfenidone and Nintedanib in Interstitial Lung Diseases Other than Idiopathic Pulmonary Fibrosis: A Systematic Review.
Topics: Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung Diseases, Interstitial; Pyridones; Treatment Outcome | 2023 |
Efficacy of N-acetylcysteine plus pirfenidone in the treatment of idiopathic pulmonary fibrosis: a systematic review and meta-analysis.
Topics: Acetylcysteine; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Treatment Outcome | 2023 |
Overview of idiopathic pulmonary fibrosis, evidence-based guidelines, and recent developments in the treatment landscape.
Topics: Age Distribution; Aging; Antineoplastic Agents; Chronic Disease; Comorbidity; Disease Progression; Health Expenditures; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Patient Education as Topic; Practice Guidelines as Topic; Pyridones; Sex Distribution | 2019 |
The therapy of idiopathic pulmonary fibrosis: what is next?
Topics: Animals; Comorbidity; Disease Progression; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung; Lung Transplantation; Molecular Targeted Therapy; Palliative Care; Pyridones; Respiratory System Agents; Respiratory Therapy; Risk Factors; Treatment Outcome | 2019 |
Antifibrotic therapy for idiopathic pulmonary fibrosis: time to treat.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Protein Kinase Inhibitors; Pyridones; Time-to-Treatment | 2019 |
Treatment of idiopathic pulmonary fibrosis with Nintedanib: an update.
Topics: Disease Progression; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Protein Kinase Inhibitors; Pyridones; Treatment Outcome | 2019 |
Antifibrotic therapy for fibrotic lung disease beyond idiopathic pulmonary fibrosis.
Topics: Animals; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung; Lung Diseases, Interstitial; Pyridones; Treatment Outcome; Vital Capacity | 2019 |
Nutrition in Patients with Idiopathic Pulmonary Fibrosis: Critical Issues Analysis and Future Research Directions.
Topics: Behavior; Cardiovascular Diseases; Comorbidity; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Muscle Strength; Nutrition Assessment; Nutrition Disorders; Nutritional Physiological Phenomena; Nutritional Status; Patient Education as Topic; Pyridones | 2020 |
Efficacy, safety, and tolerability of combined pirfenidone and N-acetylcysteine therapy: a systematic review and meta-analysis.
Topics: Acetylcysteine; Administration, Inhalation; Anti-Inflammatory Agents, Non-Steroidal; Carbon Monoxide; Drug Therapy, Combination; Free Radical Scavengers; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Randomized Controlled Trials as Topic; Treatment Outcome; Vital Capacity | 2020 |
Evolution and treatment of idiopathic pulmonary fibrosis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antibodies; Connective Tissue Growth Factor; Drug Therapy, Combination; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Integrins; Leukotriene Antagonists; Lung Transplantation; Microbiota; Middle Aged; Multimorbidity; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Protein Kinase Inhibitors; Pyridones; Serum Amyloid P-Component | 2020 |
Lung transplantation for idiopathic pulmonary fibrosis.
Topics: Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Comorbidity; Disease Progression; Frailty; Gastroesophageal Reflux; Humans; Hypertension, Pulmonary; Idiopathic Interstitial Pneumonias; Idiopathic Pulmonary Fibrosis; Indoles; Lung Neoplasms; Lung Transplantation; Prognosis; Pyridones; Telomere Shortening | 2020 |
Pamrevlumab for the treatment of idiopathic pulmonary fibrosis.
Topics: Animals; Antibodies, Monoclonal, Humanized; Connective Tissue Growth Factor; Disease Progression; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Treatment Outcome | 2020 |
Idiopathic pulmonary fibrosis: Molecular mechanisms and potential treatment approaches.
Topics: Aged; Aged, 80 and over; Biomarkers; Disease Progression; Female; Fibrosis; Humans; Idiopathic Pulmonary Fibrosis; Lung; Lung Transplantation; Male; Middle Aged; Prognosis; Pyridones; Telomere | 2020 |
Shedding light on developmental drugs for idiopathic pulmonary fibrosis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Development; Drug Discovery; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Protein Kinase Inhibitors; Pyridones | 2020 |
[Antifibrotic therapy and progressive lung fibrosis].
Topics: Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung; Pulmonary Fibrosis; Pyridones | 2020 |
Advances in Targeted Therapy for Progressive Fibrosing Interstitial Lung Disease.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; Humans; Idiopathic Pulmonary Fibrosis; Immunologic Factors; Immunosuppressive Agents; Indoles; Lung Diseases, Interstitial; Protein Kinase Inhibitors; Pulmonary Fibrosis; Pyridones; Vital Capacity | 2020 |
Burden of idiopathic pulmonary fibrosis on patients' emotional well being and quality of life: a literature review.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cough; Dyspnea; Fatigue; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung; Mental Health; Protein Kinase Inhibitors; Pyridones; Quality of Life | 2020 |
Pharmacological management of Idiopathic Pulmonary Fibrosis: current and emerging options.
Topics: Disease Progression; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Randomized Controlled Trials as Topic | 2021 |
Systematic Review and Meta-analysis of Pirfenidone, Nintedanib, and Pamrevlumab for the Treatment of Idiopathic Pulmonary Fibrosis.
Topics: Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Treatment Outcome | 2021 |
Distinct improvement of pulmonary function, ground-glass opacity, hypoxia and physical findings in an idiopathic pulmonary fibrosis patient after pirfenidone treatment : a case report with a review of the literature.
Topics: Humans; Hypoxia; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones; Tomography, X-Ray Computed | 2020 |
An updated safety review of the drug treatments for idiopathic pulmonary fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Patient Education as Topic; Protein Kinase Inhibitors; Pyridones; Randomized Controlled Trials as Topic | 2021 |
Emerging drugs for the treatment of idiopathic pulmonary fibrosis: 2020 phase II clinical trials.
Topics: Animals; Clinical Trials, Phase II as Topic; Drug Design; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Molecular Targeted Therapy; Pyridones; Randomized Controlled Trials as Topic | 2021 |
Impact of Antifibrotic Therapy on Mortality and Acute Exacerbation in Idiopathic Pulmonary Fibrosis: A Systematic Review and Meta-Analysis.
Topics: Antifibrotic Agents; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Mortality; Pyridones; Symptom Flare Up; Treatment Outcome | 2021 |
Clinical trial research in focus: why do so many clinical trials fail in IPF?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Drugs, Investigational; Enzyme Inhibitors; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Research Design; Treatment Failure | 2017 |
Idiopathic Pulmonary Fibrosis: Molecular Endotypes of Fibrosis Stratifying Existing and Emerging Therapies.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Enzyme Inhibitors; Genotype; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Molecular Targeted Therapy; Phenotype; Precision Medicine; Pyridones | 2017 |
Pirfenidone and Nintedanib for Treatment of Idiopathic Pulmonary Fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Fibrinolytic Agents; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Protein-Tyrosine Kinases; Pyridones | 2017 |
Model-based Meta-Analysis on the Efficacy of Pharmacological Treatments for Idiopathic Pulmonary Fibrosis.
Topics: Humans; Idiopathic Pulmonary Fibrosis; Indoles; Models, Statistical; Pyridones; Regression Analysis; Treatment Outcome; Vital Capacity | 2017 |
Current approaches to the management of idiopathic pulmonary fibrosis.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Comorbidity; Disease Progression; Enzyme Inhibitors; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung Diseases, Interstitial; Lung Transplantation; Middle Aged; Palliative Care; Patient Education as Topic; Practice Guidelines as Topic; Prevalence; Pyridones; Quality of Life; Young Adult | 2017 |
Managing Idiopathic Pulmonary Fibrosis: Which Drug for Which Patient?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Decision Making; Disease Management; Drug-Related Side Effects and Adverse Reactions; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Vital Capacity | 2017 |
Efficacy and adverse events of pirfenidone in treating idiopathic pulmonary fibrosis.
Topics: Humans; Idiopathic Pulmonary Fibrosis; Meta-Analysis as Topic; Placebos; Pyridones; Randomized Controlled Trials as Topic; Respiratory Function Tests | 2017 |
Are newly launched pharmacotherapies efficacious in treating idiopathic pulmonary fibrosis? Or is there still more work to be done?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; Drug Approval; Drug Therapy, Combination; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Randomized Controlled Trials as Topic; Treatment Outcome | 2017 |
Therapeutic targets in idiopathic pulmonary fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; Drug Therapy, Combination; Enzyme Inhibitors; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Molecular Targeted Therapy; Pyridones; Receptors, Fibroblast Growth Factor; Receptors, Platelet-Derived Growth Factor; Receptors, Vascular Endothelial Growth Factor | 2017 |
Severe idiopathic pulmonary fibrosis: what can be done?
Topics: Disease Progression; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung; Lung Transplantation; Palliative Care; Pyridones; Respiratory Function Tests; Severity of Illness Index; Tomography, X-Ray Computed; Treatment Outcome | 2017 |
Pharmacotherapy for idiopathic pulmonary fibrosis: current landscape and future potential.
Topics: Animals; Diffusion of Innovation; Disease Progression; Drug Discovery; Drugs, Investigational; Forecasting; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung; Pyridones; Remission Induction; Respiratory System Agents; Severity of Illness Index; Treatment Outcome | 2017 |
Nintedanib for Idiopathic Pulmonary Fibrosis.
Topics: Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Diarrhea; Drug Therapy, Combination; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Protein Kinase Inhibitors; Pyridones | 2019 |
Idiopathic pulmonary fibrosis: lessons from clinical trials over the past 25 years.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Disease Progression; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Treatment Outcome | 2017 |
Pirfenidone safety and adverse event management in idiopathic pulmonary fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Disease-Free Survival; Humans; Idiopathic Pulmonary Fibrosis; Lung; Medication Adherence; Pyridones; Recovery of Function; Risk Factors; Time Factors; Treatment Outcome | 2017 |
Idiopathic pulmonary fibrosis: pathogenesis and management.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Disease Management; Disease Progression; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Tomography, X-Ray Computed | 2018 |
[Nintedanib in the treatment of fibrosing interstital lung diseases].
Topics: Disease Progression; Drug Therapy, Combination; Female; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Male; Practice Guidelines as Topic; Protein Kinase Inhibitors; Pyridones; Treatment Outcome | 2018 |
An update on emerging drugs for the treatment of idiopathic pulmonary fibrosis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; Drug Design; Genetic Predisposition to Disease; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones | 2018 |
Idiopathic Pulmonary Fibrosis.
Topics: Diagnosis, Differential; Dyspnea; Enzyme Inhibitors; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung; Oxygen Inhalation Therapy; Prognosis; Pyridones; Risk Factors; Tomography, X-Ray Computed; Transforming Growth Factor beta | 2018 |
Japanese guideline for the treatment of idiopathic pulmonary fibrosis.
Topics: Acetylcysteine; Administration, Inhalation; Adrenal Cortex Hormones; Antineoplastic Combined Chemotherapy Protocols; Comorbidity; Disease Progression; Drug Therapy, Combination; Evidence-Based Medicine; Glycine; Humans; Idiopathic Pulmonary Fibrosis; Immunosuppressive Agents; Indoles; Japan; Lung Neoplasms; Meta-Analysis as Topic; Practice Guidelines as Topic; Prognosis; Pyridones; Quality of Health Care; Sulfonamides; Survival Rate | 2018 |
Use of animal models in IPF research.
Topics: Animals; Bleomycin; Disease Models, Animal; Drug Development; Drug Evaluation, Preclinical; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Respiratory Function Tests | 2018 |
Idiopathic Pulmonary Fibrosis and Antifibrotic Treatments: Focus on Experimental Studies.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Enzyme Inhibitors; Fibroblasts; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones | 2018 |
Pirfenidone for Treating Idiopathic Pulmonary Fibrosis: An Evidence Review Group Perspective of a NICE Single Technology Appraisal.
Topics: Cost-Benefit Analysis; Humans; Idiopathic Pulmonary Fibrosis; Network Meta-Analysis; Pyridones; Randomized Controlled Trials as Topic; Referral and Consultation | 2019 |
Progress in Understanding and Treating Idiopathic Pulmonary Fibrosis.
Topics: Aged; Biopsy, Needle; Chronic Disease; Comprehension; Disease Management; Disease Progression; Female; Humans; Idiopathic Pulmonary Fibrosis; Immunohistochemistry; Indoles; Lung Transplantation; Male; Middle Aged; Precision Medicine; Prognosis; Pyridones; Respiratory Function Tests; Risk Assessment; Severity of Illness Index; Treatment Outcome | 2019 |
Idiopathic Pulmonary Fibrosis and Lung Cancer: Mechanisms and Molecular Targets.
Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung Neoplasms; Myofibroblasts; Pyridones | 2019 |
Inflammation and immunity in IPF pathogenesis and treatment.
Topics: Adaptive Immunity; Anti-Inflammatory Agents; Clinical Trials as Topic; Extracellular Matrix; Fibroblasts; Fibrosis; Humans; Idiopathic Pulmonary Fibrosis; Immunity, Innate; Indoles; Inflammation; Protein Kinase Inhibitors; Pyridones | 2019 |
Evaluation and management of Idiopathic Pulmonary Fibrosis.
Topics: Biomarkers; Chronic Disease; Cough; Diagnosis, Differential; Disease Progression; Dyspnea; Humans; Idiopathic Pulmonary Fibrosis; Indoles; L-Lactate Dehydrogenase; Mucin-1; Pyridones; Respiratory Function Tests; Tomography, X-Ray Computed; Vital Capacity | 2019 |
Idiopathic Pulmonary Fibrosis: New and Emerging Treatment Options.
Topics: Aging; Drug Development; Extracellular Matrix; Fibroblasts; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Randomized Controlled Trials as Topic | 2019 |
Current and Future Idiopathic Pulmonary Fibrosis Therapy.
Topics: Anti-Inflammatory Agents; Disease Progression; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones | 2019 |
Pirfenidone: a novel agent for the treatment of idiopathic pulmonary fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Pulmonary Fibrosis; Pyridones | 2013 |
[Clinical experience with pirfenidone for the treatment of idiopathic pulmonary fibrosis].
Topics: Adrenal Cortex Hormones; Aged; Anti-Inflammatory Agents, Non-Steroidal; Drug Therapy, Combination; Evidence-Based Medicine; Female; Germany; Humans; Idiopathic Pulmonary Fibrosis; Male; Prevalence; Pyridones; Treatment Outcome | 2013 |
An update on idiopathic pulmonary fibrosis.
Topics: Animals; Early Diagnosis; Humans; Idiopathic Pulmonary Fibrosis; Lung; Predictive Value of Tests; Prognosis; Pyridones; Risk Factors | 2013 |
The role of pirfenidone in the treatment of idiopathic pulmonary fibrosis.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Drug-Related Side Effects and Adverse Reactions; Evidence-Based Medicine; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Prevalence; Pyridones; Risk Factors; Survival Rate; Treatment Outcome | 2013 |
Pharmacological treatment of idiopathic pulmonary fibrosis: from the past to the future.
Topics: Animals; History, 20th Century; History, 21st Century; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Respiratory System Agents; Treatment Outcome | 2013 |
Pirfenidone for the treatment of idiopathic pulmonary fibrosis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease-Free Survival; Humans; Idiopathic Pulmonary Fibrosis; Prognosis; Pyridones; Risk Assessment; Severity of Illness Index; Survival Rate; Vital Capacity | 2014 |
The diagnosis and treatment of idiopathic pulmonary fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Combined Modality Therapy; Humans; Idiopathic Pulmonary Fibrosis; Lung Transplantation; Prevalence; Pyridones; Risk Factors; Survival Rate; Tomography, X-Ray Computed; Treatment Outcome | 2013 |
Pirfenidone: an update on clinical trial data and insights from everyday practice.
Topics: Clinical Trials, Phase III as Topic; Evidence-Based Medicine; Humans; Idiopathic Pulmonary Fibrosis; Lung; Pyridones; Randomized Controlled Trials as Topic; Respiratory System Agents; Time Factors; Treatment Outcome | 2014 |
Pirfenidone in idiopathic pulmonary fibrosis: expert panel discussion on the management of drug-related adverse events.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Disease Management; Disease-Free Survival; Drug-Related Side Effects and Adverse Reactions; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Respiratory Function Tests; Tumor Necrosis Factor-alpha | 2014 |
Comprehensive assessment of the long-term safety of pirfenidone in patients with idiopathic pulmonary fibrosis.
Topics: Adult; Aged; Aged, 80 and over; Alanine Transaminase; Anti-Inflammatory Agents, Non-Steroidal; Aspartate Aminotransferases; Biomarkers; Dose-Response Relationship, Drug; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones; Randomized Controlled Trials as Topic; Time Factors | 2014 |
New therapeutic targets in idiopathic pulmonary fibrosis. Aiming to rein in runaway wound-healing responses.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Enzyme Inhibitors; Humans; Idiopathic Pulmonary Fibrosis; Immunosuppressive Agents; Indoles; Pyridones; Wound Healing | 2014 |
Pirfenidone for the treatment of idiopathic pulmonary fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Quality of Life; Respiratory Function Tests; Treatment Outcome | 2014 |
Recent evidence for pharmacological treatment of idiopathic pulmonary fibrosis.
Topics: Acetylcysteine; Anti-Inflammatory Agents; Azathioprine; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Prednisone; Pyridones; Randomized Controlled Trials as Topic | 2014 |
[Idiopathic pulmonary fibrosis].
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones | 2014 |
[Antifibrotic treatment].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Cystine; Drug Approval; Free Radical Scavengers; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Randomized Controlled Trials as Topic; Survival Rate; Treatment Outcome; Vital Capacity | 2014 |
Two new drugs for idiopathic pulmonary fibrosis.
Topics: Drug Approval; Drugs, Investigational; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Tumor Necrosis Factor-alpha; United States | 2014 |
Novel approaches to pulmonary fibrosis.
Topics: Biomarkers; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones | 2014 |
Usefulness of a disease severity staging classification system for IPF in Japan: 20 years of experience from empirical evidence to randomized control trial enrollment.
Topics: Acetylcysteine; Empirical Research; Evidence-Based Medicine; Humans; Idiopathic Pulmonary Fibrosis; Japan; Oximetry; Patient Selection; Pyridones; Randomized Controlled Trials as Topic; Severity of Illness Index; Time Factors; Vital Capacity | 2015 |
Pirfenidone: a review of its use in idiopathic pulmonary fibrosis.
Topics: Administration, Oral; Animals; Humans; Idiopathic Pulmonary Fibrosis; Pyridones | 2015 |
Idiopathic pulmonary fibrosis: an update.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Enzyme Inhibitors; Health Services Needs and Demand; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Middle Aged; Pyridones; Risk Factors | 2015 |
Pharmacological treatment of idiopathic pulmonary fibrosis: an update.
Topics: Animals; Comorbidity; Disease Models, Animal; Disease Progression; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung; Pyridones; Risk Factors; Time Factors; Treatment Outcome | 2015 |
IPF Care: a support program for patients with idiopathic pulmonary fibrosis treated with pirfenidone in Europe.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Disease Management; Europe; Humans; Idiopathic Pulmonary Fibrosis; Middle Aged; Nurses; Patient Education as Topic; Pyridones; Quality of Life; Surveys and Questionnaires; Treatment Outcome; United Kingdom | 2015 |
Long-term clinical and real-world experience with pirfenidone in the treatment of idiopathic pulmonary fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Registries | 2015 |
The changing treatment landscape in idiopathic pulmonary fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Europe; Humans; Idiopathic Pulmonary Fibrosis; Practice Guidelines as Topic; Pyridones; United States | 2015 |
Do all patients with idiopathic pulmonary fibrosis warrant a trial of therapeutic intervention? A pro-con perspective.
Topics: Antineoplastic Agents; Clinical Trials as Topic; Disease Management; Disease Progression; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung; Pyridones; Treatment Outcome; Tumor Necrosis Factor-alpha | 2015 |
Comparing new treatments for idiopathic pulmonary fibrosis--a network meta-analysis.
Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Enzyme Inhibitors; Free Radical Scavengers; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Treatment Outcome | 2015 |
Idiopathic pulmonary fibrosis: Recent advances on pharmacological therapy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Randomized Controlled Trials as Topic | 2015 |
Idiopathic pulmonary fibrosis: the turning point is now!
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Disease Progression; Enzyme Inhibitors; Gastroesophageal Reflux; Humans; Hypertension, Pulmonary; Idiopathic Pulmonary Fibrosis; Indoles; Practice Guidelines as Topic; Pyridones | 2015 |
Management of Idiopathic Pulmonary Fibrosis in the Elderly Patient: Addressing Key Questions.
Topics: Age Factors; Aged; Antineoplastic Agents; Disease Management; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Patient-Centered Care; Precision Medicine; Prognosis; Pyridones | 2015 |
Practical considerations in the pharmacologic treatment of idiopathic pulmonary fibrosis.
Topics: Clinical Trials as Topic; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Treatment Outcome | 2015 |
Challenges in IPF diagnosis, current management and future perspectives.
Topics: Aged; Biopsy, Needle; Disease Management; Disease Progression; Female; Humans; Idiopathic Pulmonary Fibrosis; Immunohistochemistry; Male; Middle Aged; Needs Assessment; Practice Guidelines as Topic; Prognosis; Pyridones; Respiratory Function Tests; Risk Assessment; Severity of Illness Index; Survival Analysis; Tomography, X-Ray Computed | 2015 |
Pirfenidone for Idiopathic Pulmonary Fibrosis: A Systematic Review and Meta-Analysis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Pulmonary Fibrosis; Pyridones | 2015 |
Idiopathic pulmonary fibrosis: from clinical trials to real-life experiences.
Topics: Evidence-Based Medicine; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Randomized Controlled Trials as Topic; Research Design; Treatment Outcome | 2015 |
[Novel therapies for idiopathic pulmonary fibrosis].
Topics: Disease Progression; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Respiratory Mucosa; Survival Rate | 2015 |
Novel mechanisms and treatment of idiopathic pulmonary fibrosis.
Topics: Clinical Trials as Topic; Disease Progression; Environmental Exposure; Fibroblasts; Gastroesophageal Reflux; Genetic Predisposition to Disease; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung; Mutation; Myofibroblasts; Polymorphism, Genetic; Prognosis; Pyridones; Treatment Outcome | 2015 |
Update in Interstitial Lung Disease 2014.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Doxycycline; Enzyme Inhibitors; Humans; Idiopathic Pulmonary Fibrosis; Immunosuppressive Agents; Indoles; Lung Diseases, Interstitial; Lymphangioleiomyomatosis; Pyridones; Sarcoidosis, Pulmonary; Sirolimus; Smoking; Tomography, X-Ray Computed; Tumor Necrosis Factor-alpha | 2015 |
Pirfenidone Initiates a New Era in the Treatment of Idiopathic Pulmonary Fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; Disease-Free Survival; Humans; Idiopathic Pulmonary Fibrosis; Pyridones | 2016 |
Pirfenidone for idiopathic pulmonary fibrosis: analysis of pooled data from three multinational phase 3 trials.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials, Phase III as Topic; Disease Progression; Exercise Test; Female; Forced Expiratory Volume; Humans; Idiopathic Pulmonary Fibrosis; International Cooperation; Male; Middle Aged; Pulmonary Diffusing Capacity; Pyridones; Randomized Controlled Trials as Topic; Treatment Outcome; Vital Capacity | 2016 |
Targeted Therapy for Idiopathic Pulmonary Fibrosis: Where To Now?
Topics: Aging; Clinical Trials, Phase II as Topic; Drug Approval; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Molecular Targeted Therapy; Pyridones | 2016 |
Pharmacological Treatment of Idiopathic Pulmonary Fibrosis: Current Approaches, Unsolved Issues, and Future Perspectives.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Comorbidity; Disease Management; Disease Progression; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones | 2015 |
Therapeutic advances in idiopathic pulmonary fibrosis.
Topics: Anti-Inflammatory Agents; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones | 2016 |
Drug Treatment of Idiopathic Pulmonary Fibrosis: Systematic Review and Network Meta-Analysis.
Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Azathioprine; Bayes Theorem; Bosentan; Endothelin Receptor Antagonists; Enzyme Inhibitors; Etanercept; Free Radical Scavengers; Humans; Idiopathic Pulmonary Fibrosis; Imatinib Mesylate; Immunosuppressive Agents; Indoles; Interferon-gamma; Phenylpropionates; Pyridazines; Pyridones; Pyrimidines; Recombinant Proteins; Sulfonamides; Vital Capacity; Warfarin | 2016 |
Treatment of idiopathic pulmonary fibrosis: a network meta-analysis.
Topics: Acetylcysteine; Adult; Anticoagulants; Bayes Theorem; Female; Free Radical Scavengers; Humans; Idiopathic Pulmonary Fibrosis; Immunosuppressive Agents; Indoles; Male; Middle Aged; Pyridones; Quality of Life; Treatment Outcome; Young Adult | 2016 |
[Anti-fibrotics as novel therapy for idiopathic pulmonary fibrosis].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Evidence-Based Medicine; Fibrinolytic Agents; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Kidney Diseases; Pyridones; Respiratory System Agents; Treatment Outcome | 2016 |
Antacid therapy and disease outcomes in idiopathic pulmonary fibrosis: a pooled analysis.
Topics: Aged; Antacids; Clinical Trials, Phase III as Topic; Disease Progression; Exercise Tolerance; Female; Gastroesophageal Reflux; Humans; Idiopathic Pulmonary Fibrosis; Kaplan-Meier Estimate; Lung; Male; Middle Aged; Patient Admission; Pyridones; Randomized Controlled Trials as Topic; Treatment Outcome; Vital Capacity; Walk Test | 2016 |
Pharmacological management of IPF.
Topics: Disease Progression; Humans; Idiopathic Pulmonary Fibrosis; Immunomodulation; Immunosuppressive Agents; Indoles; Male; Middle Aged; Practice Guidelines as Topic; Pyridones; Randomized Controlled Trials as Topic; Treatment Outcome | 2016 |
A safety evaluation of pirfenidone for the treatment of idiopathic pulmonary fibrosis.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Pulmonary Fibrosis; Medication Adherence; Patient Education as Topic; Pyridones; Randomized Controlled Trials as Topic | 2016 |
Recent Advances and Future Needs in Interstitial Lung Diseases.
Topics: Clinical Trials as Topic; Forecasting; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung Diseases, Interstitial; Pyridones; Quality of Life | 2016 |
Pirfenidone, nintedanib and N-acetylcysteine for the treatment of idiopathic pulmonary fibrosis: A systematic review and meta-analysis.
Topics: Acetylcysteine; Anti-Inflammatory Agents; Enzyme Inhibitors; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Practice Guidelines as Topic; Pyridones; Randomized Controlled Trials as Topic; Treatment Outcome | 2016 |
Therapeutic Approach to Adult Fibrotic Lung Diseases.
Topics: Alveolitis, Extrinsic Allergic; Anti-Inflammatory Agents, Non-Steroidal; Connective Tissue Diseases; Disease Progression; Enzyme Inhibitors; Humans; Idiopathic Pulmonary Fibrosis; Immunosuppressive Agents; Indoles; Lung Diseases, Interstitial; Prognosis; Pyridones | 2016 |
The safety of new drug treatments for idiopathic pulmonary fibrosis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Enzyme Inhibitors; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones | 2016 |
Pirfenidone: Clinical trials and clinical practice in patients with idiopathic pulmonary fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Pulmonary Fibrosis; Pyridones | 2016 |
Is personalised medicine the key to heterogeneity in idiopathic pulmonary fibrosis?
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Disease Progression; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Precision Medicine; Prognosis; Pyridones | 2017 |
Treatment of idiopathic pulmonary fibrosis: a position paper from a Nordic expert group.
Topics: Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones | 2017 |
Effect of pirfenidone on mortality: pooled analyses and meta-analyses of clinical trials in idiopathic pulmonary fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cause of Death; Clinical Trials, Phase III as Topic; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Randomized Controlled Trials as Topic; Treatment Outcome; Vital Capacity | 2017 |
A Cost-Effectiveness Analysis of Nintedanib in Idiopathic Pulmonary Fibrosis in the UK.
Topics: Acetylcysteine; Adult; Cost-Benefit Analysis; Enzyme Inhibitors; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Markov Chains; Models, Economic; Pyridones; Quality of Life; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Treatment Outcome; United Kingdom | 2017 |
Is pirfenidone effective for idiopathic pulmonary fibrosis?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Randomized Controlled Trials as Topic | 2017 |
The earlier, the better: Impact of early diagnosis on clinical outcome in idiopathic pulmonary fibrosis.
Topics: Disease Progression; Early Diagnosis; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Italy; Patient Care Team; Patient-Centered Care; Prognosis; Protein Kinase Inhibitors; Pyridones | 2017 |
Pirfenidone for the treatment of idiopathic pulmonary fibrosis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; Endpoint Determination; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Randomized Controlled Trials as Topic; Treatment Outcome | 2017 |
Systematic Review and Network Meta-analysis of Idiopathic Pulmonary Fibrosis Treatments.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Enzyme Inhibitors; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Randomized Controlled Trials as Topic; Treatment Outcome | 2017 |
Survival in Idiopathic Pulmonary Fibrosis: Perspectives from Pulmonary Arterial Hypertension.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Hypertension, Pulmonary; Idiopathic Pulmonary Fibrosis; Indoles; Phosphodiesterase 5 Inhibitors; Pyridones; Survival Rate | 2017 |
Advances in understanding of idiopathic pulmonary fibrosis.
Topics: Adrenal Cortex Hormones; Animals; Anticoagulants; Antioxidants; Humans; Idiopathic Pulmonary Fibrosis; Immunologic Factors; Lung Transplantation; Pyridones | 2009 |
Pirfenidone: antifibrotic agent for idiopathic pulmonary fibrosis.
Topics: Animals; Clinical Trials as Topic; Disease Progression; Drug Approval; Humans; Idiopathic Pulmonary Fibrosis; Lung; Pyridones; Recovery of Function; Respiratory System Agents; Severity of Illness Index; Time Factors; Treatment Outcome | 2010 |
Pirfenidone in idiopathic pulmonary fibrosis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Disease Models, Animal; Evidence-Based Medicine; Humans; Idiopathic Pulmonary Fibrosis; Lung; Pyridones; Research Design; Treatment Outcome | 2010 |
Pirfenidone in idiopathic pulmonary fibrosis: the CAPACITY program.
Topics: Australia; Double-Blind Method; Europe; Evidence-Based Medicine; Forced Expiratory Volume; Humans; Idiopathic Pulmonary Fibrosis; Lung; Mexico; North America; Pyridones; Respiratory System Agents; Time Factors; Treatment Outcome; Vital Capacity | 2011 |
Emerging potential treatments: new hope for idiopathic pulmonary fibrosis patients?
Topics: Animals; Clinical Trials as Topic; Evidence-Based Medicine; Humans; Idiopathic Pulmonary Fibrosis; Lung; Pyridones; Respiratory System Agents; Treatment Outcome | 2011 |
Pirfenidone: in idiopathic pulmonary fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Randomized Controlled Trials as Topic; Severity of Illness Index; Treatment Outcome | 2011 |
Pirfenidone treatment of idiopathic pulmonary fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Vital Capacity | 2012 |
[Idiopathic pulmonary fibrosis: modern guideline-concordant diagnostics and innovative treatment].
Topics: Acetylcysteine; Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Antioxidants; Biopsy; Expectorants; Humans; Idiopathic Pulmonary Fibrosis; Lung; Lung Transplantation; Oxygen Inhalation Therapy; Practice Guidelines as Topic; Pyridones; Tomography, X-Ray Computed | 2012 |
Unravelling the progressive pathophysiology of idiopathic pulmonary fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; Enzyme Inhibitors; Epithelial Cells; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pulmonary Alveoli; Pyridones | 2012 |
Assessing the treatment effect from multiple trials in idiopathic pulmonary fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Disease-Free Survival; Humans; Idiopathic Pulmonary Fibrosis; Interferon-gamma; Pyridones; Recombinant Proteins; Treatment Outcome | 2012 |
Changing the idiopathic pulmonary fibrosis treatment approach and improving patient outcomes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Humans; Idiopathic Pulmonary Fibrosis; Prognosis; Pyridones; Survival Rate; Treatment Outcome; Vital Capacity | 2012 |
Pirfenidone: significant treatment effects in idiopathic pulmonary fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Evidence-Based Medicine; Humans; Idiopathic Pulmonary Fibrosis; Pyridones | 2012 |
The big clinical trials in idiopathic pulmonary fibrosis.
Topics: Bosentan; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Randomized Controlled Trials as Topic; Sulfonamides; Treatment Outcome | 2012 |
Current and novel drug therapies for idiopathic pulmonary fibrosis.
Topics: Acetylcysteine; Amino Acid Oxidoreductases; Animals; Antiviral Agents; Gastroesophageal Reflux; Humans; Idiopathic Pulmonary Fibrosis; Interleukin-13; Lung Transplantation; MicroRNAs; Protein Kinase Inhibitors; Pyridones; Transforming Growth Factor beta | 2012 |
[Characteristics and management of idiopathic pulmonary fibrosis: INSIGHTS-IPF registry].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Cross-Cultural Comparison; Cross-Sectional Studies; Female; Germany; Humans; Idiopathic Pulmonary Fibrosis; Lung; Male; Prognosis; Prospective Studies; Pyridones; Quality of Life; Randomized Controlled Trials as Topic; Rare Diseases; Registries; Sex Factors; Survival Analysis; Treatment Outcome | 2012 |
49 trial(s) available for pirfenidone and Cryptogenic Fibrosing Alveolitis
Article | Year |
---|---|
Effect of sildenafil added to antifibrotic treatment in idiopathic pulmonary fibrosis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; Drug Therapy, Combination; Female; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung; Male; Middle Aged; Propensity Score; Pyridones; Sildenafil Citrate; Treatment Outcome; Vital Capacity | 2021 |
Randomized phase II study of nintedanib with or without pirfenidone in patients with idiopathic pulmonary fibrosis who experienced disease progression during prior pirfenidone administration.
Topics: Disease Progression; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Treatment Outcome; Vital Capacity | 2022 |
Inhaled pirfenidone solution (AP01) for IPF: a randomised, open-label, dose-response trial.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Australia; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones; Treatment Outcome; Vital Capacity | 2023 |
Pirfenidone in fibrotic hypersensitivity pneumonitis: a double-blind, randomised clinical trial of efficacy and safety.
Topics: Adult; Alveolitis, Extrinsic Allergic; COVID-19; Disease Progression; Double-Blind Method; Humans; Idiopathic Pulmonary Fibrosis; Pandemics; Pyridones; Treatment Outcome; Vital Capacity | 2023 |
Efficacy and Safety of Pirfenidone in Advanced Versus Non-Advanced Idiopathic Pulmonary Fibrosis: Post-Hoc Analysis of Six Clinical Studies.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Treatment Outcome; Vital Capacity | 2023 |
Prolonged-release pirfenidone in patients with pulmonary fibrosis as a phenotype of post-acute sequelae of COVID-19 pneumonia. Safety and efficacy.
Topics: COVID-19; Disease Progression; Dyspnea; Humans; Idiopathic Pulmonary Fibrosis; Phenotype; Pneumonia; Pyridones | 2023 |
Gastrointestinal pirfenidone adverse events in idiopathic pulmonary fibrosis depending on diet: the MADIET clinical trial.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diet; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Treatment Outcome; Vital Capacity | 2023 |
Cardiovascular Risks, Bleeding Risks, and Clinical Events from 3 Phase III Trials of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Atrial Fibrillation; Cardiovascular Agents; Cardiovascular Diseases; Coronary Artery Disease; Female; Hemorrhage; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones; Retrospective Studies; Risk Factors; Treatment Outcome; Warfarin | 2019 |
Longitudinal clinical outcomes in a real-world population of patients with idiopathic pulmonary fibrosis: the PROOF registry.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Belgium; Disease Progression; Female; Follow-Up Studies; Humans; Idiopathic Pulmonary Fibrosis; Longitudinal Studies; Luxembourg; Male; Middle Aged; Mortality; Pyridones; Registries; Respiratory Function Tests; Treatment Outcome | 2019 |
An Open-label Study With Pirfenidone on Chronic Hypersensitivity Pneumonitis.
Topics: Adult; Alveolitis, Extrinsic Allergic; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Carbon Monoxide; Double-Blind Method; Female; Humans; Idiopathic Pulmonary Fibrosis; Immunosuppressive Agents; Lung; Male; Middle Aged; Prednisone; Prospective Studies; Pyridones; Quality of Life; Treatment Outcome; Vital Capacity | 2020 |
Home Monitoring in Patients with Idiopathic Pulmonary Fibrosis. A Randomized Controlled Trial.
Topics: Aged; Aged, 80 and over; Anxiety; Depression; Disease Management; Female; Home Care Services; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Male; Middle Aged; Netherlands; Patient Reported Outcome Measures; Pyridones; Quality of Life; Spirometry; Telemedicine; Vital Capacity | 2020 |
Patient expectations, experiences and satisfaction with nintedanib and pirfenidone in idiopathic pulmonary fibrosis: a quantitative study.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Male; Middle Aged; Motivation; Patient Satisfaction; Prospective Studies; Pyridones; Self Report; Surveys and Questionnaires; Treatment Outcome | 2020 |
Pirfenidone plus inhaled N-acetylcysteine for idiopathic pulmonary fibrosis: a randomised trial.
Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Pulmonary Fibrosis; Japan; Pyridones; Treatment Outcome; Vital Capacity | 2021 |
Efficacy and safety of sildenafil added to pirfenidone in patients with advanced idiopathic pulmonary fibrosis and risk of pulmonary hypertension: a double-blind, randomised, placebo-controlled, phase 2b trial.
Topics: Aged; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension, Pulmonary; Idiopathic Pulmonary Fibrosis; Male; Pyridones; Sildenafil Citrate | 2021 |
Serum surfactant protein D as a predictive biomarker for the efficacy of pirfenidone in patients with idiopathic pulmonary fibrosis: a post-hoc analysis of the phase 3 trial in Japan.
Topics: Aged; Biomarkers; Body Mass Index; Double-Blind Method; Female; Humans; Idiopathic Pulmonary Fibrosis; Lung; Male; Middle Aged; Predictive Value of Tests; Prospective Studies; Pulmonary Surfactant-Associated Protein D; Pyridones; Time Factors; Treatment Outcome; Vital Capacity | 2020 |
The Effect of Pirfenidone on the Prescription of Antibiotics and Antitussive Drugs in Patients With Idiopathic Pulmonary Fibrosis: A Post Hoc Exploratory Analysis of Phase III Clinical Trial.
Topics: Aged; Anti-Bacterial Agents; Antifibrotic Agents; Antitussive Agents; Disease Progression; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Polypharmacy; Pyridones; Treatment Outcome | 2021 |
A Pharmacokinetic Bioequivalence Study Comparing Pirfenidone Tablet and Capsule Dosage Forms in Healthy Adult Volunteers.
Topics: Adolescent; Adult; Area Under Curve; Biological Availability; Capsules; Cross-Over Studies; Dose-Response Relationship, Drug; Female; Healthy Volunteers; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones; Tablets; Therapeutic Equivalency; Young Adult | 2017 |
Nintedanib with Add-on Pirfenidone in Idiopathic Pulmonary Fibrosis. Results of the INJOURNEY Trial.
Topics: Aged; Disease Progression; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Male; Middle Aged; Patient Safety; Pyridones; Risk Assessment; Severity of Illness Index; Survival Rate; Treatment Outcome | 2018 |
An Open-Label Study of the Long-Term Safety of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis (RECAP).
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones | 2017 |
Sildenafil added to pirfenidone in patients with advanced idiopathic pulmonary fibrosis and risk of pulmonary hypertension: A Phase IIb, randomised, double-blind, placebo-controlled study - Rationale and study design.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials, Phase II as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension, Pulmonary; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Multicenter Studies as Topic; Pyridones; Randomized Controlled Trials as Topic; Research Design; Sildenafil Citrate; Vasodilator Agents | 2018 |
Safety of nintedanib added to pirfenidone treatment for idiopathic pulmonary fibrosis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Drug Therapy, Combination; Female; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Internationality; Lung; Male; Middle Aged; Pyridones; Treatment Outcome; Vital Capacity | 2018 |
Efficacy of Pirfenidone in the Context of Multiple Disease Progression Events in Patients With Idiopathic Pulmonary Fibrosis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cause of Death; Disease Progression; Dose-Response Relationship, Drug; Europe; Female; Follow-Up Studies; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones; Survival Rate; Treatment Outcome; United States; Vital Capacity | 2019 |
Phase 2 clinical trial of PBI-4050 in patients with idiopathic pulmonary fibrosis.
Topics: Acetates; Aged; Aged, 80 and over; Drug Therapy, Combination; Female; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Male; Middle Aged; Patient Safety; Pyridones; Treatment Outcome | 2019 |
Effect of pirfenidone in patients with more advanced idiopathic pulmonary fibrosis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones; Treatment Outcome | 2019 |
Pirfenidone Treatment in Individuals with Idiopathic Pulmonary Fibrosis: Impact of Timing of Treatment Initiation.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Prognosis; Pyridones; Risk Assessment; Severity of Illness Index; Survival Rate; Time-to-Treatment; Treatment Outcome; Vital Capacity | 2019 |
Pirfenidone in patients with idiopathic pulmonary fibrosis and more advanced lung function impairment.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Carbon Monoxide; Case-Control Studies; Dyspnea; Exercise Tolerance; Female; Hospitalization; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Mortality; Placebos; Pulmonary Diffusing Capacity; Pyridones; Respiratory Function Tests; Treatment Outcome; Vital Capacity | 2019 |
Effect of pirfenidone on breathlessness in patients with idiopathic pulmonary fibrosis.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Dyspnea; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones; Quality of Life; Severity of Illness Index; Sex Factors; Surveys and Questionnaires; Time Factors; Treatment Outcome; Vital Capacity | 2019 |
A phase 3 trial of pirfenidone in patients with idiopathic pulmonary fibrosis.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Disease Progression; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones; Treatment Outcome; Vital Capacity | 2014 |
Analysis of lung function and survival in RECAP: An open-label extension study of pirfenidone in patients with idiopathic pulmonary fibrosis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Australia; Disease Progression; Europe; Female; Humans; Idiopathic Pulmonary Fibrosis; Lung; Male; Middle Aged; North America; Prospective Studies; Pulmonary Diffusing Capacity; Pyridones; Time Factors; Treatment Outcome; Vital Capacity | 2014 |
Safety and pharmacokinetics of nintedanib and pirfenidone in idiopathic pulmonary fibrosis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Japan; Male; Middle Aged; Patient Safety; Pyridones; Treatment Outcome; Vital Capacity | 2015 |
Unified baseline and longitudinal mortality prediction in idiopathic pulmonary fibrosis.
Topics: Age Factors; Aged; Algorithms; Female; Follow-Up Studies; Humans; Idiopathic Pulmonary Fibrosis; Interferon-gamma; Kaplan-Meier Estimate; Male; Middle Aged; Models, Statistical; Predictive Value of Tests; Prognosis; Pyridones; Recombinant Proteins; Risk Assessment; Sex Factors; Statistics as Topic | 2015 |
Sensitivity Analyses of the Change in FVC in a Phase 3 Trial of Pirfenidone for Idiopathic Pulmonary Fibrosis.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones; Reproducibility of Results; Sensitivity and Specificity; Treatment Outcome; Vital Capacity | 2015 |
Validation of test performance characteristics and minimal clinically important difference of the 6-minute walk test in patients with idiopathic pulmonary fibrosis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Exercise Test; Female; Follow-Up Studies; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Prognosis; Pyridones; Quality of Life; Surveys and Questionnaires; Time Factors; Tumor Necrosis Factor-alpha; Walking | 2015 |
Inhaled Interferon and Diffusion Capacity in Idiopathic Pulmonary Fibrosis (IPF).
Topics: Administration, Inhalation; Aged; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Idiopathic Pulmonary Fibrosis; Interferon-gamma; Male; Maximum Tolerated Dose; Middle Aged; Predictive Value of Tests; Pulmonary Diffusing Capacity; Pyridones; Recombinant Proteins; Reference Values; Respiratory Function Tests; Risk Assessment; Severity of Illness Index; Treatment Outcome | 2015 |
Double-Blind Randomized Trial of Pirfenidone in Chinese Idiopathic Pulmonary Fibrosis Patients.
Topics: Asian People; Double-Blind Method; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones | 2015 |
Predictors of Mortality Poorly Predict Common Measures of Disease Progression in Idiopathic Pulmonary Fibrosis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; Dyspnea; Female; Hospitalization; Humans; Idiopathic Pulmonary Fibrosis; Male; Models, Statistical; Proportional Hazards Models; Pyridones; Risk Assessment; Risk Factors; Surveys and Questionnaires; Vital Capacity | 2016 |
Effect of continued treatment with pirfenidone following clinically meaningful declines in forced vital capacity: analysis of data from three phase 3 trials in patients with idiopathic pulmonary fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; Disease-Free Survival; Dose-Response Relationship, Drug; Humans; Idiopathic Pulmonary Fibrosis; Kaplan-Meier Estimate; Pyridones; Research Design; Treatment Outcome; Vital Capacity | 2016 |
Safety and tolerability of acetylcysteine and pirfenidone combination therapy in idiopathic pulmonary fibrosis: a randomised, double-blind, placebo-controlled, phase 2 trial.
Topics: Acetylcysteine; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug Therapy, Combination; Europe; Expectorants; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones; Treatment Outcome | 2016 |
A phase II trial evaluating the efficacy and safety of perioperative pirfenidone for prevention of acute exacerbation of idiopathic pulmonary fibrosis in lung cancer patients undergoing pulmonary resection: West Japan Oncology Group 6711 L (PEOPLE Study).
Topics: Administration, Oral; Disease Progression; Drug Administration Schedule; Humans; Idiopathic Pulmonary Fibrosis; Japan; Lung Neoplasms; Pneumonectomy; Pyridones; Risk Factors; Time Factors; Treatment Outcome | 2016 |
Efficacy of pirfenidone in patients with idiopathic pulmonary fibrosis with more preserved lung function.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; Dyspnea; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones; Respiratory Function Tests; Surveys and Questionnaires; Tidal Volume; Treatment Outcome; Vital Capacity | 2016 |
Effect of statins on disease-related outcomes in patients with idiopathic pulmonary fibrosis.
Topics: Adult; Aged; Aged, 80 and over; Disease Progression; Double-Blind Method; Female; Hospitalization; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones; Risk Factors; Treatment Outcome | 2017 |
Efficacy of simtuzumab versus placebo in patients with idiopathic pulmonary fibrosis: a randomised, double-blind, controlled, phase 2 trial.
Topics: Aged; Aged, 80 and over; Amino Acid Oxidoreductases; Antibodies, Monoclonal, Humanized; Disease-Free Survival; Double-Blind Method; Drug Administration Schedule; Enzyme Inhibitors; Female; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Male; Middle Aged; Pyridones; Treatment Outcome | 2017 |
Predicting Life Expectancy for Pirfenidone in Idiopathic Pulmonary Fibrosis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Female; Follow-Up Studies; Humans; Idiopathic Pulmonary Fibrosis; Internationality; Life Expectancy; Male; Middle Aged; Predictive Value of Tests; Pyridones; Survival Rate; Treatment Outcome | 2017 |
Pirfenidone in idiopathic pulmonary fibrosis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Disease-Free Survival; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Oximetry; Patient Compliance; Placebo Effect; Pyridones; Treatment Outcome; Vital Capacity; Young Adult | 2010 |
Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): two randomised trials.
Topics: Administration, Oral; Aged; Anti-Inflammatory Agents, Non-Steroidal; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Idiopathic Pulmonary Fibrosis; Kaplan-Meier Estimate; Male; Middle Aged; Pyridones; Vital Capacity | 2011 |
The clinical significance of 5% change in vital capacity in patients with idiopathic pulmonary fibrosis: extended analysis of the pirfenidone trial.
Topics: Aged; Disease Progression; Disease-Free Survival; Double-Blind Method; Humans; Idiopathic Pulmonary Fibrosis; Japan; Kaplan-Meier Estimate; Lung; Middle Aged; Pyridones; Respiratory System Agents; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome; Vital Capacity | 2011 |
Pirfenidone in idiopathic pulmonary fibrosis: the CAPACITY program.
Topics: Australia; Double-Blind Method; Europe; Evidence-Based Medicine; Forced Expiratory Volume; Humans; Idiopathic Pulmonary Fibrosis; Lung; Mexico; North America; Pyridones; Respiratory System Agents; Time Factors; Treatment Outcome; Vital Capacity | 2011 |
Exploratory analysis of a phase III trial of pirfenidone identifies a subpopulation of patients with idiopathic pulmonary fibrosis as benefiting from treatment.
Topics: Adult; Aged; Double-Blind Method; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones; Treatment Outcome; Vital Capacity; Young Adult | 2011 |
CT analysis of the effect of pirfenidone in patients with idiopathic pulmonary fibrosis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Idiopathic Pulmonary Fibrosis; Lung; Male; Pyridones; Reproducibility of Results; Sensitivity and Specificity; Tomography, X-Ray Computed; Treatment Outcome | 2014 |
293 other study(ies) available for pirfenidone and Cryptogenic Fibrosing Alveolitis
Article | Year |
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Antifibrotic and anticancer action of 5-ene amino/iminothiazolidinones.
Topics: Amination; Antineoplastic Agents; Cell Line; Cell Proliferation; Cell Survival; Crystallography, X-Ray; Fibroblasts; Humans; Idiopathic Pulmonary Fibrosis; Imines; Lung; Models, Molecular; Superoxides; Thiazolidines | 2016 |
Discovery of 2-[[2-Ethyl-6-[4-[2-(3-hydroxyazetidin-1-yl)-2-oxoethyl]piperazin-1-yl]-8-methylimidazo[1,2-a]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)thiazole-5-carbonitrile (GLPG1690), a First-in-Class Autotaxin Inhibitor Undergoing Clinical Evaluation
Topics: Animals; Humans; Idiopathic Pulmonary Fibrosis; Imidazoles; Mice; Mice, Knockout; Phosphoric Diester Hydrolases; Pyrimidines; Rats | 2017 |
Discovery of 4-Methylquinazoline Based PI3K Inhibitors for the Potential Treatment of Idiopathic Pulmonary Fibrosis.
Topics: Animals; Bleomycin; Cell Line; Cell Proliferation; Crystallography, X-Ray; Drug Evaluation, Preclinical; Half-Life; Humans; Idiopathic Pulmonary Fibrosis; Isoenzymes; Lung; Mice; Mice, Inbred ICR; Molecular Conformation; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Quinazolines; Signal Transduction; Structure-Activity Relationship | 2019 |
Synthesis and biological activity of thieno[3,2-d]pyrimidines as potent JAK3 inhibitors for the treatment of idiopathic pulmonary fibrosis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Dose-Response Relationship, Drug; Epithelial Cells; Female; Humans; Idiopathic Pulmonary Fibrosis; Janus Kinase 3; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; Molecular Structure; Protein Kinase Inhibitors; Pyrimidines; Structure-Activity Relationship | 2020 |
Discovery of Novel Selective and Orally Bioavailable Phosphodiesterase-1 Inhibitors for the Efficient Treatment of Idiopathic Pulmonary Fibrosis.
Topics: Animals; Bleomycin; Cell Differentiation; Cyclic Nucleotide Phosphodiesterases, Type 1; Drug Design; Humans; Idiopathic Pulmonary Fibrosis; Lung; Male; Molecular Structure; Myofibroblasts; Phosphodiesterase Inhibitors; Protein Binding; Pyrazoles; Pyrimidinones; Rats, Sprague-Dawley; Structure-Activity Relationship; Thermodynamics | 2020 |
Discovery of the S1P2 Antagonist GLPG2938 (1-[2-Ethoxy-6-(trifluoromethyl)-4-pyridyl]-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea), a Preclinical Candidate for the Treatment of Idiopathic Pulmonary Fibrosis.
Topics: Animals; CHO Cells; Cricetulus; Drug Design; Humans; Idiopathic Pulmonary Fibrosis; Interleukin-8; Male; Mice; Pyridazines; Sphingosine-1-Phosphate Receptors; Structure-Activity Relationship; Tissue Distribution | 2021 |
Structural Modifications of Nimodipine Lead to Novel PDE1 Inhibitors with Anti-pulmonary Fibrosis Effects.
Topics: Animals; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 1; Idiopathic Pulmonary Fibrosis; Nimodipine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rats | 2022 |
Discovery of a novel Pleuromutilin derivative as anti-IPF lead compound via high-throughput assay.
Topics: Animals; Bleomycin; Diterpenes; Fibroblasts; High-Throughput Screening Assays; Idiopathic Pulmonary Fibrosis; Lung; Mice; Mice, Inbred C57BL; NIH 3T3 Cells; Pleuromutilins; Polycyclic Compounds; Transforming Growth Factor beta1 | 2022 |
Uniportal video-assisted thoracic surgery and perioperative pirfenidone for lung cancer and idiopathic pulmonary fibrosis: a case report.
Topics: Aged; Female; Humans; Idiopathic Pulmonary Fibrosis; Lung Neoplasms; Neoplasm Recurrence, Local; Pyridones; Thoracic Surgery, Video-Assisted | 2021 |
Evaluation of efficacy and safety of pirfenidone 200 mg tablets in patients with idiopathic pulmonary fibrosis in a real-life setting
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cough; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones; Retrospective Studies; Tablets; Treatment Outcome | 2021 |
Comparison of pirfenidone and corticosteroid treatments at the COVID-19 pneumonia with the guide of artificial intelligence supported thoracic computed tomography.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antifibrotic Agents; Artificial Intelligence; COVID-19; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Retrospective Studies; SARS-CoV-2; Tomography, X-Ray Computed; Treatment Outcome; Vital Capacity | 2021 |
Pirfenidone vs. nintedanib in patients with idiopathic pulmonary fibrosis: a retrospective cohort study.
Topics: Aged; Aged, 80 and over; Ambulatory Care; Antifibrotic Agents; Drug Costs; Female; Hospital Costs; Hospitalization; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Male; Middle Aged; Pyridones; Retrospective Studies; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome | 2021 |
Recent trends in pirfenidone and nintedanib use for idiopathic pulmonary fibrosis in Australia.
Topics: Australia; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Treatment Outcome | 2021 |
Feasibility and safety of treatment switch from Pirfenidone to Nintedanib in patients with idiopathic pulmonary fibrosis: a real-world observational study.
Topics: Aged; Aged, 80 and over; Antifibrotic Agents; Disease Progression; Dose-Response Relationship, Drug; Feasibility Studies; Female; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Male; Prospective Studies; Pyridones; Respiratory Function Tests; Treatment Outcome; Vital Capacity | 2021 |
Treatment of Idiopathic Pulmonary Fibrosis with Capsule or Tablet Formulations of Pirfenidone in the Real-Life French RaDiCo-ILD Cohort.
Topics: Cohort Studies; France; Humans; Idiopathic Pulmonary Fibrosis; Lung Diseases, Interstitial; Pyridones; Tablets; Treatment Outcome | 2022 |
Survival of patients with idiopathic pulmonary fibrosis and pulmonary hypertension under therapy with nintedanib or pirfenidone.
Topics: Humans; Hypertension, Pulmonary; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Treatment Outcome | 2022 |
Effect of antifibrotic therapy in patients with idiopathic pulmonary fibrosis undergoing lung transplant in the peri and post-operative period.
Topics: Aged; Antifibrotic Agents; Female; Hospitalization; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung Transplantation; Male; Perioperative Period; Pyridones; Retrospective Studies; Vital Capacity; Waiting Lists; Weight Loss | 2021 |
The antifibrotic effect of pheretima protein is mediated by the TGF-β1/Smad2/3 pathway and attenuates inflammation in bleomycin-induced idiopathic pulmonary fibrosis.
Topics: Animals; Anti-Inflammatory Agents; Bleomycin; Disease Models, Animal; Freeze Drying; Idiopathic Pulmonary Fibrosis; Inflammation; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred C57BL; Oligochaeta; Proteins; Pyridones; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta1 | 2022 |
Effects of low-dose pirfenidone on survival and lung function decline in patients with idiopathic pulmonary fibrosis (IPF): Results from a real-world study.
Topics: Age Factors; Aged; Aged, 80 and over; Body Mass Index; Disease-Free Survival; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones; Respiratory Function Tests; Retrospective Studies; Risk Factors; Survival Rate | 2021 |
Cost-effectiveness of the anti-fibrotics for the treatment of idiopathic pulmonary fibrosis in the United States.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antifibrotic Agents; Cost of Illness; Cost-Benefit Analysis; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Markov Chains; Protein Kinase Inhibitors; Pyridones; United States | 2022 |
Differential Discontinuation Profiles between Pirfenidone and Nintedanib in Patients with Idiopathic Pulmonary Fibrosis.
Topics: Antineoplastic Agents; Disease Progression; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Prognosis; Pyridones; Treatment Outcome | 2022 |
Study of overall survival associated with nintedanib and pirfenidone in patients with idiopathic pulmonary fibrosis: a real-life comparison.
Topics: Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones | 2023 |
Integrated bioinformatics analysis identifies established and novel TGFβ1-regulated genes modulated by anti-fibrotic drugs.
Topics: Adaptor Proteins, Vesicular Transport; Antifibrotic Agents; Cadherins; Cell Adhesion Molecule-1; Computational Biology; Extracellular Matrix Proteins; Female; Gene Expression Regulation; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Interleukins; Male; Membrane Proteins; Nerve Tissue Proteins; Pyridones; Racemases and Epimerases; Repressor Proteins; Tensins; Transforming Growth Factor beta | 2022 |
[Desensitization to pirfenidone. Report of one case].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Idiopathic Pulmonary Fibrosis; Pyridones | 2021 |
Safety and tolerability of pirfenidone in asbestosis: a prospective multicenter study.
Topics: Asbestosis; Humans; Idiopathic Pulmonary Fibrosis; Prospective Studies; Pyridones; Treatment Outcome | 2022 |
Analyses of the Efficacy and Safety of Antifibrotic Therapies in Non-IPF Pulmonary Fibrosis, Progressing Despite Management.
Topics: Humans; Idiopathic Pulmonary Fibrosis; Pyridones | 2022 |
Desensitization to Pirfenidone in a Patient Diagnosed With Idiopathic Pulmonary Fibrosis and Hypersensitivity to Antifibrotic Drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Treatment Outcome | 2022 |
Role of transient receptor potential vanilloid 4 in therapeutic antifibrotic effects of pirfenidone.
Topics: Animals; Antineoplastic Agents; Bleomycin; Humans; Idiopathic Pulmonary Fibrosis; Ligands; Lung; Mice; Pyridones; TRPV Cation Channels | 2022 |
Real-world safety profiles of pirfenidone and nintedanib in idiopathic pulmonary fibrosis patients.
Topics: Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Treatment Outcome | 2022 |
Survival and lung function decline in patients with definite, probable and possible idiopathic pulmonary fibrosis treated with pirfenidone.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Pulmonary Fibrosis; Lung; Probability; Pyridones; Retrospective Studies; Treatment Outcome; Vital Capacity | 2022 |
Nintedanib vs pirfenidone in the management of COVID-19 lung fibrosis: A single-centre study.
Topics: Adult; C-Reactive Protein; COVID-19 Drug Treatment; Ferritins; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Middle Aged; Prednisolone; Pyridones; Treatment Outcome | 2022 |
Impact of body weight change on clinical outcomes in patients with idiopathic pulmonary fibrosis receiving pirfenidone.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Carbon Monoxide; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Pyridones; Retrospective Studies; Treatment Outcome; Vital Capacity; Weight Loss | 2022 |
Inhaled deep eutectic solvent based-nanoemulsion of pirfenidone in idiopathic pulmonary fibrosis.
Topics: Animals; Deep Eutectic Solvents; Idiopathic Pulmonary Fibrosis; Pyridones; Rats; Spectroscopy, Fourier Transform Infrared; X-Ray Microtomography | 2022 |
Healthcare resource use and associated costs in patients receiving pirfenidone or nintedanib for idiopathic pulmonary fibrosis.
Topics: Delivery of Health Care; Humans; Idiopathic Pulmonary Fibrosis; Indoles | 2023 |
Combination of esomeprazole and pirfenidone enhances antifibrotic efficacy in vitro and in a mouse model of TGFβ-induced lung fibrosis.
Topics: Animals; Disease Models, Animal; Esomeprazole; Idiopathic Pulmonary Fibrosis; Mice; Prospective Studies; Proton Pump Inhibitors; Retrospective Studies; Transforming Growth Factor beta | 2022 |
Inhibition of MRTF activation as a clinically achievable anti-fibrotic mechanism for pirfenidone.
Topics: Fibroblasts; Fibrosis; Humans; Idiopathic Pulmonary Fibrosis; Lung; Myofibroblasts; Trans-Activators; Transcription Factors | 2023 |
Factors associated with dose reduction of pirfenidone in patients with idiopathic pulmonary fibrosis: A study based on real-world clinical data.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Drug Tapering; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Retrospective Studies; Treatment Outcome; Vital Capacity | 2023 |
Ziritaxestat, a Novel Autotaxin Inhibitor, and Lung Function in Idiopathic Pulmonary Fibrosis: The ISABELA 1 and 2 Randomized Clinical Trials.
Topics: Administration, Oral; Aged; Clinical Trials, Phase III as Topic; Female; Humans; Idiopathic Pulmonary Fibrosis; Lung; Male; Middle Aged; Multicenter Studies as Topic; Phosphodiesterase Inhibitors; Quality of Life; Randomized Controlled Trials as Topic; Respiratory Physiological Phenomena; Respiratory System Agents; Treatment Outcome | 2023 |
Use of pirfenidone in pediatric patients with interstitial lung disease and pulmonary fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Child; Humans; Idiopathic Pulmonary Fibrosis; Lung; Lung Diseases, Interstitial; Pulmonary Fibrosis; Pyridones | 2023 |
Diagnostic finding on high-resolution computed tomography (HRCT) predicts a good response to pirfenidone in patients with idiopathic pulmonary fibrosis.
Topics: Humans; Idiopathic Pulmonary Fibrosis; Lung; Pyridones; Retrospective Studies; Tomography, X-Ray Computed | 2023 |
A fibroblastic foci-targeting and hypoxia-cleavable delivery system of pirfenidone for the treatment of idiopathic pulmonary fibrosis.
Topics: Animals; Fibroblasts; Fibrosis; Idiopathic Pulmonary Fibrosis; Lung; Mice | 2023 |
Effects of comorbid chronic kidney disease on mortality in idiopathic pulmonary fibrosis patients and influence of pirfenidone.
Topics: Comorbidity; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Pyridones; Renal Insufficiency, Chronic; Treatment Outcome | 2023 |
Choice of Methodology Impacts Outcome in Indirect Comparisons of Drugs for Idiopathic Pulmonary Fibrosis.
Topics: Bias; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Research Design; Treatment Outcome | 2019 |
Improving outcomes and managing costs in idiopathic pulmonary fibrosis.
Topics: Antineoplastic Agents; Chronic Disease; Comorbidity; Cost of Illness; Health Expenditures; Health Resources; Health Services; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Medication Adherence; Patient Care Management; Patient Education as Topic; Practice Guidelines as Topic; Pyridones; Quality of Life; Registries | 2019 |
Self-reported Gastrointestinal Side Effects of Antifibrotic Drugs in Dutch Idiopathic Pulmonary Fibrosis patients.
Topics: Adult; Aged; Aged, 80 and over; Cross-Sectional Studies; Female; Gastrointestinal Diseases; Health Care Surveys; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Male; Middle Aged; Netherlands; Pyridones; Risk Assessment; Risk Factors; Self Report; Time Factors; Treatment Outcome | 2019 |
Pirfenidone in real life: A retrospective observational multicentre study in Italian patients with idiopathic pulmonary fibrosis.
Topics: Aged; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Pyridones; Retrospective Studies; Vital Capacity | 2019 |
Prognostic impact of an early marginal decline in forced vital capacity in idiopathic pulmonary fibrosis patients treated with pirfenidone.
Topics: Humans; Idiopathic Pulmonary Fibrosis; Prognosis; Pyridones; Vital Capacity | 2019 |
[The clinical experience of pirfenidone based on corticosteroids and immunosuppressant treatment for interstitial pneumonia with autoimmune features].
Topics: Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents, Non-Steroidal; Autoimmune Diseases; Female; Humans; Idiopathic Pulmonary Fibrosis; Immunosuppressive Agents; Lung Diseases, Interstitial; Male; Middle Aged; Pyridones; Retrospective Studies; Treatment Outcome | 2019 |
Antifibrotic treatment response and prognostic predictors in patients with idiopathic pulmonary fibrosis and exposed to occupational dust.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; Dust; Female; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Italy; Male; Middle Aged; Multivariate Analysis; Occupational Exposure; Prognosis; Prospective Studies; Pyridones; Regression Analysis; Respiratory Function Tests; Treatment Outcome | 2019 |
Interferon-γ enhances the antifibrotic effects of pirfenidone by attenuating IPF lung fibroblast activation and differentiation.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cell Differentiation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Female; Fibroblasts; Humans; Idiopathic Pulmonary Fibrosis; Interferon-gamma; Lung; Male; Pyridones; Young Adult | 2019 |
Choice of antifibrotic medication and disease severity predict weight loss in idiopathic pulmonary fibrosis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Female; Follow-Up Studies; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Male; Middle Aged; Protein Kinase Inhibitors; Pyridones; Severity of Illness Index; Weight Loss | 2019 |
Real-life comparison of pirfenidone and nintedanib in patients with idiopathic pulmonary fibrosis: A 24-month assessment.
Topics: Carbon Monoxide; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung; Pyridones; Time Factors; Vital Capacity | 2019 |
Perioperative pirfenidone treatment for lung cancer patients with idiopathic pulmonary fibrosis.
Topics: Disease Progression; Humans; Idiopathic Pulmonary Fibrosis; Lung Neoplasms; Perioperative Care; Postoperative Period; Pyridones; Retrospective Studies; Treatment Outcome | 2020 |
Aerosol Pirfenidone Pharmacokinetics after Inhaled Delivery in Sheep: a Viable Approach to Treating Idiopathic Pulmonary Fibrosis.
Topics: Administration, Inhalation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Idiopathic Pulmonary Fibrosis; Lung; Lymph; Pyridones; Sheep | 2019 |
Real-world experiences: Efficacy and tolerability of pirfenidone in clinical practice.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Body Mass Index; Carbon Monoxide; China; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones; Retrospective Studies; Tomography, X-Ray Computed; Treatment Outcome; Vital Capacity | 2020 |
Surfactant protein A as a biomarker of outcomes of anti-fibrotic drug therapy in patients with idiopathic pulmonary fibrosis.
Topics: Aged; Biomarkers; Disease Progression; Female; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Logistic Models; Male; Middle Aged; Mucin-1; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Protein D; Pyridones; Retrospective Studies; Treatment Outcome; Vital Capacity | 2020 |
Patient and site characteristics associated with pirfenidone and nintedanib use in the United States; an analysis of idiopathic pulmonary fibrosis patients enrolled in the Pulmonary Fibrosis Foundation Patient Registry.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Female; Foundations; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Male; Middle Aged; Patient Participation; Protein Kinase Inhibitors; Pyridones; Registries; United States | 2020 |
Deterioration of high-resolution computed tomography findings predicts disease progression after initial decline in forced vital capacity in idiopathic pulmonary fibrosis patients treated with pirfenidone.
Topics: Disease Progression; Humans; Idiopathic Pulmonary Fibrosis; Predictive Value of Tests; Pyridones; Radiographic Image Enhancement; Retrospective Studies; Tomography, X-Ray Computed; Vital Capacity | 2020 |
Perioperative pirfenidone treatment as prophylaxis against acute exacerbation of idiopathic pulmonary fibrosis: a single-center analysis.
Topics: Aged; Aged, 80 and over; Disease Progression; Female; Follow-Up Studies; Humans; Idiopathic Pulmonary Fibrosis; Lung Neoplasms; Male; Middle Aged; Negative Results; Patient Selection; Perioperative Care; Postoperative Complications; Prognosis; Pyridones; Survival Rate | 2020 |
Disease progression across the spectrum of idiopathic pulmonary fibrosis: A multicentre study.
Topics: Antineoplastic Agents; Disease Progression; Female; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Italy; Longitudinal Studies; Male; Middle Aged; Mortality; Practice Patterns, Physicians'; Pyridones; Treatment Outcome | 2020 |
Safety and Efficacy of Pirfenidone in Advanced Idiopathic Pulmonary Fibrosis: A Nationwide Post-Marketing Surveillance Study in Korean Patients.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Idiopathic Pulmonary Fibrosis; Lung; Male; Middle Aged; Product Surveillance, Postmarketing; Pyridones; Republic of Korea; Respiratory Function Tests; Severity of Illness Index; Treatment Outcome | 2020 |
Conditional deletion of Nedd4-2 in lung epithelial cells causes progressive pulmonary fibrosis in adult mice.
Topics: Adult; Aged; Animals; Biopsy; Disease Models, Animal; Epithelial Cells; Epithelial Sodium Channels; Humans; Idiopathic Pulmonary Fibrosis; Lung; Mice; Mice, Knockout; Middle Aged; Mucin-5B; Nedd4 Ubiquitin Protein Ligases; Proteomics; Pyridones; Ubiquitination | 2020 |
A multicentre retrospective observational study on Polish experience of pirfenidone therapy in patients with idiopathic pulmonary fibrosis: the PolExPIR study.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; Female; Humans; Idiopathic Pulmonary Fibrosis; Lung; Lung Transplantation; Male; Medication Adherence; Middle Aged; Poland; Pyridones; Respiratory Function Tests; Retrospective Studies; Treatment Outcome; Walk Test | 2020 |
The world is not enough - the value of increasing registry data in idiopathic pulmonary fibrosis.
Topics: Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Registries; United States | 2020 |
Volume-assured pressure support mode plus pirfenidone as resuscitation therapy in patients with exacerbation of idiopathic pulmonary fibrosis.
Topics: Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Combined Modality Therapy; Female; Humans; Idiopathic Pulmonary Fibrosis; Noninvasive Ventilation; Pyridones; Treatment Outcome; Vital Capacity | 2020 |
Idiopathic pulmonary fibrosis: Significance of the usual interstitial pneumonia (UIP) CT-scan patterns defined in new international guidelines.
Topics: Aged; Aged, 80 and over; Cohort Studies; Diagnostic Techniques, Respiratory System; Female; France; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Internationality; Male; Middle Aged; Practice Guidelines as Topic; Prognosis; Pyridones; Retrospective Studies; Tomography, X-Ray Computed; Treatment Outcome | 2020 |
Circulating Plasma Biomarkers of Survival in Antifibrotic-Treated Patients With Idiopathic Pulmonary Fibrosis.
Topics: Aged; Aged, 80 and over; Biomarkers; Cohort Studies; Female; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Male; Pyridones; Survival Rate | 2020 |
Photobiological study in pirfenidone-induced photosensitivity.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Dermatitis, Phototoxic; Erythema; Female; Humans; Idiopathic Pulmonary Fibrosis; Pruritus; Pyridones; Sunlight | 2020 |
Treatment patterns, healthcare resource utilization, and costs among patients with idiopathic pulmonary fibrosis treated with antifibrotic medications in US-based commercial and Medicare Supplemental claims databases: a retrospective cohort study.
Topics: Adult; Aged; Aged, 80 and over; Comparative Effectiveness Research; Female; Health Care Costs; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Logistic Models; Male; Medicare; Medication Adherence; Middle Aged; Pyridones; Retrospective Studies; Treatment Outcome; United States | 2020 |
Expert consensus on the management of adverse events and prescribing practices associated with the treatment of patients taking pirfenidone for idiopathic pulmonary fibrosis: a Delphi consensus study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Consensus; Delphi Technique; Disease Management; Drug-Related Side Effects and Adverse Reactions; Humans; Idiopathic Pulmonary Fibrosis; Practice Patterns, Physicians'; Pyridones; Treatment Outcome | 2020 |
Inhibition of mast cells: a novel mechanism by which nintedanib may elicit anti-fibrotic effects.
Topics: Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bleomycin; Cell Proliferation; Cell Survival; Chemokine CCL2; Coculture Techniques; Disease Models, Animal; Female; Fibroblasts; Fibrosis; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung; Male; Mast Cells; Middle Aged; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyridones; Rats; Recombinant Proteins; Signal Transduction; Stem Cell Factor; Vital Capacity | 2020 |
Clinical Molecular Imaging of Pulmonary CXCR4 Expression to Predict Outcome of Pirfenidone Treatment in Idiopathic Pulmonary Fibrosis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers, Pharmacological; Disease Progression; Female; Humans; Idiopathic Pulmonary Fibrosis; Immunohistochemistry; Lung; Male; Patient Acuity; Positron Emission Tomography Computed Tomography; Prognosis; Pyridones; Receptors, CXCR4; Up-Regulation | 2021 |
Healthcare use and costs among Medicare enrollees on pirfenidone versus nintedanib for idiopathic pulmonary fibrosis.
Topics: Aged; Aged, 80 and over; Comparative Effectiveness Research; Delivery of Health Care; Female; Health Care Costs; Health Services; Hospitalization; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Male; Medicare; Patient Acceptance of Health Care; Pyridones; Retrospective Studies; Treatment Outcome; United States | 2020 |
A disease progression model of longitudinal lung function decline in idiopathic pulmonary fibrosis patients.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Disease Progression; Female; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Longitudinal Studies; Lung; Male; Middle Aged; Models, Biological; Prognosis; Pyridones; Respiratory Function Tests; Risk Factors; Smoking; Time Factors; Treatment Outcome; Vital Capacity | 2021 |
Safety and effectiveness of pirfenidone combined with carboplatin-based chemotherapy in patients with idiopathic pulmonary fibrosis and non-small cell lung cancer: A retrospective cohort study.
Topics: Aged; Carboplatin; Carcinoma, Non-Small-Cell Lung; Cohort Studies; Female; Humans; Idiopathic Pulmonary Fibrosis; Immune Checkpoint Inhibitors; Lung Neoplasms; Male; Middle Aged; Pyridones; Retrospective Studies | 2020 |
Effectiveness and safety of pirfenidone for idiopathic pulmonary fibrosis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Exercise Test; Fatigue; Female; Follow-Up Studies; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Myalgia; Pyridones; Retrospective Studies; Treatment Outcome | 2020 |
Regression of Lung Squamous Cell Carcinoma after the Withdrawal of Cyclosporin A Combined with Pirfenidone Treatment in a Patient with Idiopathic Pulmonary Fibrosis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Carcinoma, Squamous Cell; Cyclosporine; Humans; Idiopathic Pulmonary Fibrosis; Lung; Lung Neoplasms; Male; Pyridones; Treatment Outcome | 2021 |
Effectiveness of pirfenidone for idiopathic pulmonary fibrosis associated with pleuroparenchymal fibroelastosis-like lesions and nonspecific interstitial pneumonia.
Topics: Humans; Idiopathic Pulmonary Fibrosis; Lung; Lung Diseases, Interstitial; Pyridones; Retrospective Studies | 2021 |
A real-world study of the dosing and tolerability of pirfenidone and its effect on survival in idiopathic pulmonary fibrosis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Female; Forced Expiratory Volume; Humans; Idiopathic Pulmonary Fibrosis; Lung; Male; Maximum Tolerated Dose; Middle Aged; Patient Safety; Prospective Studies; Pyridones; Recovery of Function; Treatment Outcome; Vital Capacity | 2020 |
Real world experience of response to pirfenidone in patients with idiopathic pulmonary fibrosis: a two centre retrospective study.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; England; Female; Humans; Idiopathic Pulmonary Fibrosis; Lung; Male; Pyridones; Recovery of Function; Retrospective Studies; Time Factors; Treatment Outcome; Vital Capacity | 2020 |
Antifibrotic and Regenerative Effects of Treamid in Pulmonary Fibrosis.
Topics: Animals; Apoptosis; Bleomycin; Capillaries; Dicarboxylic Acids; Endothelial Cells; Fibrosis; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung; Male; Mice; Mice, Inbred C57BL; Pyridones; Regeneration | 2020 |
Positive photopatch test to pirfenidone.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Dermatitis, Photoallergic; Humans; Idiopathic Pulmonary Fibrosis; Male; Patch Tests; Pyridones | 2021 |
Safety and efficacy of pirfenidone and nintedanib in patients with idiopathic pulmonary fibrosis and carrying a telomere-related gene mutation.
Topics: Humans; Idiopathic Pulmonary Fibrosis; Indoles; Mutation; Pyridones; Telomere; Treatment Outcome | 2021 |
Efficacy of low dose pirfenidone in idiopathic pulmonary fibrosis: real world experience from a tertiary university hospital.
Topics: Aged; Anorexia; Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; Dyspepsia; Female; Hospitals, University; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Nausea; Pyridones; Retrospective Studies; Tertiary Care Centers; Treatment Outcome; Vital Capacity | 2020 |
Overlapping Effects of miR-21 Inhibition and Drugs for Idiopathic Pulmonary Fibrosis: Rationale for Repurposing Nintedanib as a Novel Treatment for Ischemia/Reperfusion Injury.
Topics: Animals; Drug Repositioning; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung; MicroRNAs; Myocardial Reperfusion Injury; Protein Kinase Inhibitors; Pyridones; Signal Transduction; src-Family Kinases; ST Elevation Myocardial Infarction | 2021 |
Pirfenidone facilitates immune infiltration and enhances the antitumor efficacy of PD-L1 blockade in mice.
Topics: Animals; B7-H1 Antigen; Humans; Idiopathic Pulmonary Fibrosis; Lung Neoplasms; Mice; Pyridones | 2020 |
Adoption of the Antifibrotic Medications Pirfenidone and Nintedanib for Patients with Idiopathic Pulmonary Fibrosis.
Topics: Aged; Female; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Male; Medicare; Pharmaceutical Preparations; Pyridones; Retrospective Studies; Treatment Outcome; United States | 2021 |
Medications for Idiopathic Pulmonary Fibrosis: IPF Part 2.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Protein Kinase Inhibitors; Pyridones | 2021 |
Predictive factors for the long-term use of pirfenidone in patients with fibrosing interstitial lung disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Pulmonary Fibrosis; Lung Diseases, Interstitial; Pyridones; Retrospective Studies; Treatment Outcome; Vital Capacity | 2021 |
Antifibrotics Modify B-Cell-induced Fibroblast Migration and Activation in Patients with Idiopathic Pulmonary Fibrosis.
Topics: Antigens; B-Lymphocytes; Cell Aggregation; Cell Movement; Cell Proliferation; Fibroblasts; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Inflammation Mediators; Interleukin-6; Pneumonia; Pyridones; src-Family Kinases; TOR Serine-Threonine Kinases; Vascular Endothelial Growth Factor A | 2021 |
Lung gene expression and single cell analyses reveal two subsets of idiopathic pulmonary fibrosis (IPF) patients associated with different pathogenic mechanisms.
Topics: Biomarkers; Chemokines; Cluster Analysis; Cohort Studies; Epithelium; Fibroblasts; Gene Expression Profiling; Gene Expression Regulation; Hematopoietic Stem Cells; Humans; Idiopathic Pulmonary Fibrosis; Ligands; Lung; Machine Learning; Myeloid Cells; Myocytes, Smooth Muscle; Pericytes; Pyridones; Receptors, Cell Surface; Single-Cell Analysis | 2021 |
Pirfenidone in patients with non-IPF progressive fibrotic interstitial lung diseases: expert guidance is urgently needed.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Early Termination of Clinical Trials; Endpoint Determination; Health Services Needs and Demand; Humans; Idiopathic Pulmonary Fibrosis; Intention to Treat Analysis; Lung Diseases, Interstitial; Patient Selection; Practice Guidelines as Topic; Pyridones; Respiratory Function Tests | 2021 |
The role of pirfenidone in the treatment of interstitial pneumonia with autoimmune features.
Topics: Humans; Idiopathic Pulmonary Fibrosis; Lung Diseases, Interstitial; Pyridones; Retrospective Studies; Vital Capacity | 2022 |
Preoperative use of pirfenidone and reduced risk of postoperative severe respiratory complications in patients with idiopathic pulmonary fibrosis: Propensity score-matched analysis using a nationwide database in Japan.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Hospital Mortality; Humans; Idiopathic Pulmonary Fibrosis; Japan; Propensity Score; Pyridones; Treatment Outcome | 2021 |
Adherence, Persistence, and Effectiveness in Real Life. Multicenter Long-Term Study on the Use of Pirfenidone and Nintedanib in the Treatment of Idiopathic Pulmonary Fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Retrospective Studies; Treatment Outcome | 2022 |
Preoperative pirfenidone in idiopathic pulmonary fibrosis: A wound and injury enigma.
Topics: Humans; Idiopathic Pulmonary Fibrosis; Pyridones | 2021 |
Effectiveness of pirfenidone in idiopathic pulmonary fibrosis according to the autoantibody status: a retrospective cohort study.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Antineutrophil Cytoplasmic; Carbon Monoxide; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pulmonary Diffusing Capacity; Pyridones; Republic of Korea; Retrospective Studies; Treatment Outcome; Vital Capacity | 2021 |
Comparative outcomes in patients receiving pirfenidone or nintedanib for idiopathic pulmonary fibrosis.
Topics: Aged; Aged, 80 and over; Databases, Factual; Disease Progression; Female; France; Health Status; Hospitalization; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Male; Middle Aged; Pyridones; Respiratory System Agents; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome | 2021 |
Safety and tolerability of combination therapy with pirfenidone and nintedanib for idiopathic pulmonary fibrosis: A multicenter retrospective observational study in Japan.
Topics: Humans; Idiopathic Pulmonary Fibrosis; Indoles; Japan; Pyridones; Retrospective Studies; Treatment Outcome | 2021 |
Fibrosis on a Chip for Screening of Anti-Fibrosis Drugs.
Topics: Cells, Cultured; Drug Evaluation, Preclinical; Fibroblasts; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lab-On-A-Chip Devices; Models, Biological; Pyridones | 2021 |
Efficacy of early antifibrotic treatment for idiopathic pulmonary fibrosis.
Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Japan; Male; Middle Aged; Pyridones; Retrospective Studies; Severity of Illness Index; Treatment Outcome; Vital Capacity; Walk Test | 2021 |
Switching antifibrotics in patients with idiopathic pulmonary fibrosis: a multi-center retrospective cohort study.
Topics: Aged; Disease Progression; Drug Administration Schedule; Drug Substitution; Female; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Japan; Male; Prognosis; Propensity Score; Pyridones; Retrospective Studies; Treatment Outcome; Vital Capacity | 2021 |
Outcomes for hospitalized patients with idiopathic pulmonary fibrosis treated with antifibrotic medications.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cause of Death; Cohort Studies; Female; Hospitalization; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Logistic Models; Male; Middle Aged; Mortality; Propensity Score; Protein Kinase Inhibitors; Pyridones; Treatment Outcome; United States | 2021 |
Outcomes of patients with advanced idiopathic pulmonary fibrosis treated with nintedanib or pirfenidone in a real-world multicentre cohort.
Topics: Disease Progression; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Treatment Outcome; Vital Capacity | 2021 |
Efficacy of lower dose pirfenidone for idiopathic pulmonary fibrosis in real practice: a retrospective cohort study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Retrospective Studies; Treatment Outcome; Vital Capacity | 2022 |
Pirfenidone and nintedanib for pulmonary fibrosis in clinical practice: Tolerability and adverse drug reactions.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Enzyme Inhibitors; Female; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Male; Middle Aged; Pyridones; Retrospective Studies; Treatment Outcome | 2017 |
Development and Pretesting of a Questionnaire to Assess Patient Experiences and Satisfaction with Medications (PESaM Questionnaire).
Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Atypical Hemolytic Uremic Syndrome; Female; Humans; Idiopathic Pulmonary Fibrosis; Interviews as Topic; Male; Middle Aged; Netherlands; Orphan Drug Production; Patient Preference; Patient Satisfaction; Psychometrics; Pyridones; Quality of Life; Reproducibility of Results; Retrospective Studies; Surveys and Questionnaires | 2017 |
Acute Exacerbation and Decline in Forced Vital Capacity Are Associated with Increased Mortality in Idiopathic Pulmonary Fibrosis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Carbon Monoxide; Disease Progression; Female; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung; Male; Middle Aged; Multivariate Analysis; Pyridones; Randomized Controlled Trials as Topic; Survival Analysis; Treatment Outcome; Vital Capacity | 2017 |
Antacid Therapy and Disease Progression in Patients with Idiopathic Pulmonary Fibrosis Who Received Pirfenidone.
Topics: Aged; Antacids; Anti-Inflammatory Agents, Non-Steroidal; Cause of Death; Disease Progression; Exercise Tolerance; Female; Gastroesophageal Reflux; Histamine H2 Antagonists; Hospitalization; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Mortality; Proton Pump Inhibitors; Pyridones; Respiratory Function Tests; Survival Rate; Vital Capacity; Walk Test | 2017 |
Pirfenidone for acute exacerbation of idiopathic pulmonary fibrosis: A retrospective study.
Topics: Adrenal Cortex Hormones; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Pyridones; Recombinant Proteins; Retrospective Studies; Risk Factors; Survival Analysis; Thrombomodulin; Treatment Outcome; Vital Capacity | 2017 |
Tolerability of treatment with pirfenidone or nintedanib for pulmonary fibrosis in the real world.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pulmonary Fibrosis; Pyridones | 2017 |
Pirfenidone Reduces Respiratory-related Hospitalizations in Idiopathic Pulmonary Fibrosis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cause of Death; Double-Blind Method; Female; Hospitalization; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones; Treatment Outcome; Vital Capacity | 2017 |
Comprehensive and Individualized Patient Care in Idiopathic Pulmonary Fibrosis: Refining Approaches to Diagnosis, Prognosis, and Treatment.
Topics: Antacids; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Early Diagnosis; Early Medical Intervention; Enzyme Inhibitors; Health Behavior; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung; Patient-Centered Care; Precision Medicine; Prognosis; Pyridones; Tomography, X-Ray Computed | 2017 |
The Influence of Sex on Prognosis of Patients With Idiopathic Pulmonary Fibrosis in a Retrospective Cohort.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Idiopathic Pulmonary Fibrosis; Kaplan-Meier Estimate; Lung Transplantation; Male; Prognosis; Pyridones; Retrospective Studies; Sex Factors | 2017 |
New treatment directions for IPF: current status of ongoing and upcoming clinical trials.
Topics: Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones | 2017 |
Idiopathic Pulmonary Fibrosis: A Case Discussion.
Topics: Aged; Drug Interactions; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Male; Pharmacists; Professional Role; Pyridones | 2017 |
Treatment of idiopathic pulmonary fibrosis in Australia and New Zealand: A position statement from the Thoracic Society of Australia and New Zealand and the Lung Foundation Australia.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Australia; Comorbidity; Disease Progression; Evidence-Based Medicine; Humans; Idiopathic Pulmonary Fibrosis; Indoles; New Zealand; Pulmonary Medicine; Pyridones; Randomized Controlled Trials as Topic; Societies, Medical | 2017 |
Pirfenidone in Idiopathic Pulmonary Fibrosis "RECAP-itulating Safety into the Real World".
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Vital Capacity | 2017 |
The effects of pirfenidone in patients with an acute exacerbation of interstitial pneumonia.
Topics: Acute Disease; Aged; Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Idiopathic Pulmonary Fibrosis; Japan; Male; Prognosis; Pyridones; Recurrence; Retrospective Studies; Risk Factors; Survival Rate; Time Factors; Tomography, X-Ray Computed; Treatment Outcome; Tumor Necrosis Factor-alpha | 2018 |
Unmet needs in the treatment of idiopathic pulmonary fibrosis-insights from patient chart review in five European countries.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Europe; Female; Health Services Needs and Demand; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Male; Middle Aged; Pyridones; Severity of Illness Index; Surveys and Questionnaires; Vital Capacity | 2017 |
Serum surfactant protein D predicts the outcome of patients with idiopathic pulmonary fibrosis treated with pirfenidone.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; Disease-Free Survival; Female; Humans; Idiopathic Pulmonary Fibrosis; Logistic Models; Male; Middle Aged; Multivariate Analysis; Prognosis; Proportional Hazards Models; Pulmonary Surfactant-Associated Protein D; Pyridones; Retrospective Studies; Survival Rate; Treatment Outcome; Vital Capacity | 2017 |
Pirfenidone photosensitization in patients with idiopathic pulmonary fibrosis: a case series.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cross-Sectional Studies; Dermatitis, Phototoxic; Drug Eruptions; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Pyridones | 2018 |
Evaluating new treatment options.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; Enzyme Inhibitors; Female; Humans; Idiopathic Pulmonary Fibrosis; Immunosuppressive Agents; Indoles; Lung; Male; Middle Aged; Pyridones; United States | 2017 |
Combination Therapy and the Start of a New Epoch for Idiopathic Pulmonary Fibrosis?
Topics: Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones | 2018 |
Effect of pirfenidone on cough in patients with idiopathic pulmonary fibrosis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antitussive Agents; Cough; Diagnostic Self Evaluation; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Prospective Studies; Pyridones; Respiratory Function Tests; Treatment Outcome | 2017 |
The curse of idiopathic.
Topics: Clinical Decision-Making; Drug Approval; Humans; Idiopathic Pulmonary Fibrosis; Off-Label Use; Patient Selection; Pyridones; Risk Factors; Terminology as Topic; United States; United States Food and Drug Administration | 2018 |
Pirfenidone-induced phototoxic reaction in a patient with idiopathic pulmonary fibrosis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Dermatitis, Phototoxic; Humans; Idiopathic Pulmonary Fibrosis; Male; Pyridones; Sunlight; Treatment Outcome | 2017 |
Recommendations for perioperative management of new pharmacological antifibrotic therapy in idiopathic pulmonary fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Disease Progression; Enzyme Inhibitors; Fibroblasts; Hemodynamics; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Intraoperative Complications; Multicenter Studies as Topic; Perioperative Care; Postoperative Complications; Preanesthetic Medication; Pyridones; Vital Capacity | 2018 |
Pirfenidone-induced hyponatraemia: insight in mechanism, risk factor and management.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Enzyme Inhibitors; Female; Humans; Hyponatremia; Idiopathic Pulmonary Fibrosis; Inappropriate ADH Syndrome; Indoles; Male; Pyridones; Retrospective Studies; Risk Factors | 2017 |
Letter to the Editor: Serum surfactant protein D predicts the outcome of patients with idiopathic pulmonary fibrosis treated with pirfenidone.
Topics: Humans; Idiopathic Pulmonary Fibrosis; Pulmonary Surfactant-Associated Protein D; Pyridones; Vital Capacity | 2018 |
Drug-induced lupus erythematosus secondary to pirfenidone.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Eruptions; Female; Humans; Idiopathic Pulmonary Fibrosis; Lupus Erythematosus, Systemic; Middle Aged; Pyridones | 2018 |
Reduced incidence of lung cancer in patients with idiopathic pulmonary fibrosis treated with pirfenidone.
Topics: Aged; Antineoplastic Agents; Emphysema; Female; Humans; Idiopathic Pulmonary Fibrosis; Incidence; Lung Neoplasms; Male; Middle Aged; Proportional Hazards Models; Pyridones; Retrospective Studies; Risk; Vital Capacity | 2018 |
German Guideline for Idiopathic Pulmonary Fibrosis - Update on Pharmacological Therapies 2017.
Topics: Acetylcysteine; Adult; Aged; Aged, 80 and over; Antacids; Bosentan; Clinical Trials as Topic; Evidence-Based Medicine; Female; Gastroesophageal Reflux; Guideline Adherence; Humans; Idiopathic Pulmonary Fibrosis; Imatinib Mesylate; Indoles; Male; Middle Aged; Phenylpropionates; Pyridazines; Pyridones; Pyrimidines; Sildenafil Citrate; Sulfonamides | 2018 |
Health economic evaluation in idiopathic pulmonary fibrosis in France.
Topics: Cost-Benefit Analysis; Disease Progression; Female; France; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Male; Pyridones; Quality of Life; Quality-Adjusted Life Years; Respiratory System Agents; Treatment Outcome | 2018 |
Idiopathic pulmonary fibrosis: A guide for nurse practitioners.
Topics: Clinical Trials as Topic; Disease Management; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung; Nurse Practitioners; Patient Education as Topic; Practice Guidelines as Topic; Pyridones; Respiratory System Agents; Self-Management; Tomography, X-Ray Computed | 2018 |
Fibroblast-matrix interplay: Nintedanib and pirfenidone modulate the effect of IPF fibroblast-conditioned matrix on normal fibroblast phenotype.
Topics: Actins; Antineoplastic Agents; Cell Differentiation; Cell Proliferation; Cells, Cultured; Collagen; Culture Media, Conditioned; Drug Combinations; Extracellular Matrix; Fibroblasts; Fibrosis; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Laminin; Phenotype; Phosphorylation; Primary Cell Culture; Proteoglycans; Pyridones; Signal Transduction; Smad3 Protein; STAT3 Transcription Factor; Transforming Growth Factor beta | 2018 |
Does pirfenidone have anticancer effects in patients with idiopathic pulmonary fibrosis?
Topics: Antineoplastic Agents; Female; Humans; Idiopathic Pulmonary Fibrosis; Incidence; Lung Neoplasms; Male; Prognosis; Pyridones | 2018 |
A rare case of drug-induced hypersensitivity syndrome by pirfenidone for idiopathic pulmonary fibrosis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Biopsy; Drug Hypersensitivity Syndrome; Humans; Idiopathic Pulmonary Fibrosis; Male; Pyridones; Skin | 2018 |
Pretreatment rate of decay in forced vital capacity predicts long-term response to pirfenidone in patients with idiopathic pulmonary fibrosis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; Female; Humans; Idiopathic Pulmonary Fibrosis; Longitudinal Studies; Male; Middle Aged; Prospective Studies; Pyridones; Treatment Outcome; Vital Capacity | 2018 |
Undifferentiated Pleomorphic Sarcoma after Pirfenidone Use: A Case Report.
Topics: Histiocytoma, Malignant Fibrous; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones | 2018 |
Anti-fibrotic effects of pirfenidone and rapamycin in primary IPF fibroblasts and human alveolar epithelial cells.
Topics: A549 Cells; Alveolar Epithelial Cells; Biomarkers; Cell Movement; Epithelial-Mesenchymal Transition; Extracellular Matrix; Humans; Idiopathic Pulmonary Fibrosis; Myofibroblasts; Pyridones; Sirolimus; Transforming Growth Factor beta1 | 2018 |
Chitosan-alginate nano-carrier for transdermal delivery of pirfenidone in idiopathic pulmonary fibrosis.
Topics: Administration, Cutaneous; Alginates; Animals; Chitosan; Drug Carriers; Glucuronic Acid; Hexuronic Acids; Humans; Idiopathic Pulmonary Fibrosis; Mice; Pyridones; Skin | 2018 |
[Real-life experience with pirfenidone in idiopathic pulmonary fibrosis].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Treatment Outcome; Vital Capacity | 2018 |
[Leukocytosis during pirfenidone therapy: A case report].
Topics: Aged; Humans; Idiopathic Pulmonary Fibrosis; Leukocytosis; Male; Pyridones | 2018 |
The Efficacy and Safety of Long-term Pirfenidone Therapy in Patients with Idiopathic Pulmonary Fibrosis.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Drug Administration Schedule; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones; Retrospective Studies; Treatment Outcome; Vital Capacity | 2018 |
Macitentan reduces progression of TGF-β1-induced pulmonary fibrosis and pulmonary hypertension.
Topics: Animals; Cell Differentiation; Disease Progression; Female; Humans; Hypertension, Pulmonary; Idiopathic Pulmonary Fibrosis; Lung; Male; Myofibroblasts; Pulmonary Fibrosis; Pyridones; Pyrimidines; Rats; Rats, Sprague-Dawley; Sulfonamides; Transforming Growth Factor beta1 | 2018 |
A Rnd3/p190RhoGAP pathway regulates RhoA activity in idiopathic pulmonary fibrosis fibroblasts.
Topics: Cell Line; Down-Regulation; Extracellular Matrix; Fibroblasts; Guanine Nucleotide Exchange Factors; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Phenotype; Pyridones; Repressor Proteins; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; Signal Transduction; Transforming Growth Factor beta; Up-Regulation | 2018 |
Reply to Rajchgot et al.: Combination Nintedanib and Pirfenidone for Treatment of Idiopathic Pulmonary Fibrosis.
Topics: Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones | 2018 |
Combination Nintedanib and Pirfenidone for Treatment of Idiopathic Pulmonary Fibrosis.
Topics: Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones | 2018 |
Real-Life Experience with Pirfenidone in Idiopathic Pulmonary Fibrosis in Argentina. A Retrospective Multicenter Study.
Topics: Aged; Argentina; Asthenia; Clinical Trials, Phase III as Topic; Exanthema; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Nausea; Pyridones; Randomized Controlled Trials as Topic; Retrospective Studies; Treatment Outcome; Vital Capacity | 2019 |
Gazing into the crystal ball: can treatment response be predicted in IPF?
Topics: Biomarkers; Humans; Idiopathic Pulmonary Fibrosis; Prognosis; Pyridones | 2018 |
Prognostic and predictive biomarkers for patients with idiopathic pulmonary fibrosis treated with pirfenidone: post-hoc assessment of the CAPACITY and ASCEND trials.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Clinical Trials as Topic; Disease Progression; Female; Follow-Up Studies; Humans; Idiopathic Pulmonary Fibrosis; Male; Proportional Hazards Models; Pyridones | 2018 |
Pharmacometabolic response to pirfenidone in pulmonary fibrosis detected by MALDI-FTICR-MSI.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Idiopathic Pulmonary Fibrosis; Lung; Metabolic Networks and Pathways; Mice; Mice, Inbred C57BL; Proof of Concept Study; Pyridones; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tissue Distribution | 2018 |
Histopathological and molecular analysis of idiopathic pulmonary fibrosis lungs from patients treated with pirfenidone or nintedanib.
Topics: Aged; Alveolar Epithelial Cells; Cell Line, Tumor; Female; Fibroblasts; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung; Male; Middle Aged; Pyridones | 2019 |
Transcriptome profiling reveals the complexity of pirfenidone effects in idiopathic pulmonary fibrosis.
Topics: Adult; Aged; Cell Movement; Cell Proliferation; Down-Regulation; Extracellular Matrix; Female; Fibroblasts; Gene Expression Profiling; Gene Ontology; Humans; Hyaluronoglucosaminidase; Idiopathic Pulmonary Fibrosis; Lung; Male; Middle Aged; Proteins; Pyridones; Transcriptome | 2018 |
[The Latest Information on Respiratory Disease Management. Topics: III. New Treatment of Idiopathic Pulmonary Fibrosis].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Drug Design; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Practice Guidelines as Topic; Pyridones | 2016 |
Differential effects of Nintedanib and Pirfenidone on lung alveolar epithelial cell function in ex vivo murine and human lung tissue cultures of pulmonary fibrosis.
Topics: Alveolar Epithelial Cells; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Cell Culture Techniques; Female; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung; Mice; Mice, Inbred C57BL; Pyridones | 2018 |
Pirfenidone-Induced Sarcoid-Like Reaction: A Novel Complication.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Pulmonary Fibrosis; Lung Transplantation; Lymphatic Diseases; Male; Middle Aged; Pyridones; Sarcoidosis, Pulmonary | 2018 |
[Pirfenidone (Esbriet
Topics: Dermatitis, Phototoxic; Humans; Idiopathic Pulmonary Fibrosis; Pyridones | 2018 |
New era of Idiopathic Pulmonary Fibrosis.
Topics: Biomarkers; Cell- and Tissue-Based Therapy; Female; Genetic Predisposition to Disease; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Male; Mesenchymal Stem Cells; Pyridones; Respiratory Function Tests | 2018 |
Antifibrotic effects of a novel pirfenidone derivative in vitro and in vivo.
Topics: Animals; Bleomycin; Cells, Cultured; Disease Models, Animal; Fibroblasts; Humans; Idiopathic Pulmonary Fibrosis; Lung; Male; p38 Mitogen-Activated Protein Kinases; Pyridones; Rats; Rats, Sprague-Dawley; Smad3 Protein; Transforming Growth Factor beta1 | 2018 |
Antioxidant Activity Mediates Pirfenidone Antifibrotic Effects in Human Pulmonary Vascular Smooth Muscle Cells Exposed to Sera of Idiopathic Pulmonary Fibrosis Patients.
Topics: Aged; Antioxidants; Cell Proliferation; Collagen Type I; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Pulmonary Fibrosis; Pyridones; Reactive Oxygen Species | 2018 |
Revealing Real-Life Experiences With Antifibrotic Drugs in Idiopathic Pulmonary Fibrosis.
Topics: Argentina; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Retrospective Studies | 2019 |
Antifibrotics: Shrinking the Box of Therapeutic Uncertainty.
Topics: Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Uncertainty | 2019 |
Pirfenidone in the kaleidoscope: reflecting mechanisms through different angles.
Topics: Fibroblasts; Gene Expression Profiling; Humans; Idiopathic Pulmonary Fibrosis; Pyridones | 2018 |
Pirfenidone improves survival in IPF: results from a real-life study.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; Female; Greece; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones; Retrospective Studies; Survival Analysis; Time Factors; Treatment Outcome; Vital Capacity | 2018 |
Comparison of the antifibrotic effects of the pan-histone deacetylase-inhibitor panobinostat versus the IPF-drug pirfenidone in fibroblasts from patients with idiopathic pulmonary fibrosis.
Topics: Apoptosis; Cell Proliferation; Cell Survival; Down-Regulation; Endoplasmic Reticulum Stress; Extracellular Matrix Proteins; Female; Fibroblasts; Histone Deacetylase Inhibitors; Histones; Humans; Idiopathic Pulmonary Fibrosis; Lung; Male; Middle Aged; Panobinostat; Primary Cell Culture; Protective Agents; Pyridones; STAT3 Transcription Factor | 2018 |
Lung transplant candidates with idiopathic pulmonary fibrosis and long-term pirfenidone therapy: Treatment feasibility influences waitlist survival.
Topics: Adolescent; Adult; Child; Feasibility Studies; Female; Humans; Idiopathic Pulmonary Fibrosis; Lung Transplantation; Male; Middle Aged; Pyridones; Retrospective Studies; Survival Rate; Treatment Outcome; Waiting Lists; Young Adult | 2019 |
Absence of early metabolic response assessed by 18F-FDG PET/CT after initiation of antifibrotic drugs in IPF patients.
Topics: Aged; Animals; Antineoplastic Agents; Female; Fibrosis; Fluorodeoxyglucose F18; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Male; Mice; Mice, Inbred C57BL; Middle Aged; Positron Emission Tomography Computed Tomography; Prospective Studies; Pyridones | 2019 |
Effect of pirfenidone on lung function decline and survival: 5-yr experience from a real-life IPF cohort from the Czech EMPIRE registry.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Czech Republic; Disease Progression; Female; Follow-Up Studies; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones; Registries; Respiratory Function Tests; Survival Rate; Treatment Outcome; Vital Capacity | 2019 |
The prognostic role of Gender-Age-Physiology system in idiopathic pulmonary fibrosis patients treated with pirfenidone.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Idiopathic Pulmonary Fibrosis; Lung Transplantation; Male; Middle Aged; Mortality; Prognosis; Pyridones; Retrospective Studies; Risk Factors; Sex Factors; Treatment Outcome | 2019 |
Pirfenidone Therapy for Familial Pulmonary Fibrosis: A Real-Life Study.
Topics: Aged; Disease Progression; Female; Humans; Idiopathic Pulmonary Fibrosis; Lung; Male; Middle Aged; Pyridones; Retrospective Studies; Time Factors; Treatment Outcome | 2019 |
An Atypical Case of Idiopathic Pulmonary Fibrosis in a Patient from Africa.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Black People; Bronchoscopy; Diagnosis, Differential; Follow-Up Studies; Health Knowledge, Attitudes, Practice; Hospitals, University; Humans; Idiopathic Pulmonary Fibrosis; Lung; Lung Diseases, Interstitial; Male; Pyridones; Rare Diseases; Respiratory Function Tests; Smokers; Sweden; Tomography, X-Ray Computed; Treatment Outcome | 2019 |
The Effectiveness, Safety, and Tolerability of Pirfenidone in Idiopathic Pulmonary Fibrosis: A Retrospective Study.
Topics: Aged; Antineoplastic Agents; Cohort Studies; Female; Humans; Idiopathic Pulmonary Fibrosis; Lung; Male; Middle Aged; Pyridones; Respiratory Function Tests; Retrospective Studies; Treatment Outcome; Turkey; Vital Capacity | 2019 |
Case 10-2019: A 69-Year-Old Man with Progressive Dyspnea.
Topics: Aged; Alveolitis, Extrinsic Allergic; Biopsy; Diagnosis, Differential; Dyspnea; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung; Male; Pyridones; Radiography, Thoracic; Sarcoidosis; Tomography, X-Ray Computed | 2019 |
Pirfenidone exerts beneficial effects in patients with IPF undergoing single lung transplantation.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Combined Modality Therapy; Female; Follow-Up Studies; Germany; Graft Rejection; Graft Survival; Humans; Idiopathic Pulmonary Fibrosis; Incidence; Lung Transplantation; Male; Middle Aged; Primary Graft Dysfunction; Pyridones; Retrospective Studies; Treatment Outcome | 2019 |
Safety and Efficacy of Early and Long-Term Use of Pirfenidone in Idiopathic Pulmonary Fibrosis.
Topics: Humans; Idiopathic Pulmonary Fibrosis; Pyridones | 2019 |
Negative impact of anorexia and weight loss during prior pirfenidone administration on subsequent nintedanib treatment in patients with idiopathic pulmonary fibrosis.
Topics: Aged; Anorexia; Female; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Japan; Logistic Models; Lung; Male; Middle Aged; Multivariate Analysis; Pyridones; Retrospective Studies; Treatment Outcome; Vital Capacity; Weight Loss | 2019 |
Design of Idiopathic Pulmonary Fibrosis Clinical Trials in the Era of Approved Therapies.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Drug Approval; Drug Development; Drug Interactions; Drug Therapy, Combination; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Patient Outcome Assessment; Protein Kinase Inhibitors; Pyridones; Quality of Life; Standard of Care; Vital Capacity; Walk Test | 2019 |
Diffuse Alveolar Hemorrhage Following Pirfenidone Initiation.
Topics: Aged; Aged, 80 and over; Female; Hemorrhage; Humans; Idiopathic Pulmonary Fibrosis; Lung; Male; Pyridones | 2020 |
Pirfenidone Improves Familial Idiopathic Pulmonary Fibrosis without Affecting Serum Periostin Levels.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cell Adhesion Molecules; Cough; Disease Progression; Dyspnea; Humans; Idiopathic Pulmonary Fibrosis; Male; Mucin-1; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Protein D; Pyridones | 2019 |
Clinical Effectiveness of Antifibrotic Medications for Idiopathic Pulmonary Fibrosis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cause of Death; Female; Hospitalization; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Male; Middle Aged; Mortality; Propensity Score; Protein Kinase Inhibitors; Pyridones; Treatment Outcome; United States; Young Adult | 2019 |
Demographic and clinical profile of idiopathic pulmonary fibrosis patients in Spain: the SEPAR National Registry.
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Prospective Studies; Pyridones; Registries; Retrospective Studies; Societies, Medical; Spain | 2019 |
Comparative effectiveness of 3 Traditional Chinese Medicine treatment methods for idiopathic pulmonary fibrosis: A systematic review and network meta-analysis protocol.
Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Bayes Theorem; Drug Therapy, Combination; Drugs, Chinese Herbal; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Medicine, Chinese Traditional; Meta-Analysis as Topic; Network Meta-Analysis; Pyridones; Quality of Life; Randomized Controlled Trials as Topic; Research Design; Respiratory Function Tests; Severity of Illness Index; Survival Analysis; Systematic Reviews as Topic | 2019 |
The Anti-Fibrotic Effects of CG-745, an HDAC Inhibitor, in Bleomycin and PHMG-Induced Mouse Models.
Topics: Animals; Biguanides; Bleomycin; Disease Models, Animal; Epithelial-Mesenchymal Transition; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung; Mice; Pyridones; Republic of Korea | 2019 |
Differences in tolerability of pirfenidone between elderly and younger patients with idiopathic pulmonary fibrosis.
Topics: Adult; Aged; Aged, 80 and over; Aging; Anti-Inflammatory Agents, Non-Steroidal; Drug Tolerance; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones; Retrospective Studies; Treatment Outcome | 2019 |
Pirfenidone should be prescribed for patients with idiopathic pulmonary fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Pulmonary Fibrosis; Prescription Drugs; Pyridones; Tumor Necrosis Factor-alpha | 2013 |
Pirfenidone for IPF: pro/con debate; the 'con' viewpoint.
Topics: Humans; Idiopathic Pulmonary Fibrosis; Prescription Drugs; Pyridones | 2013 |
[Idiopathic pulmonary fibrosis: treatment with pirfenidone].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones | 2012 |
[Patient treated with pirfenidone].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones | 2012 |
Guidelines for the diagnosis and treatment of idiopathic pulmonary fibrosis. Sociedad Española de Neumología y Cirugía Torácica (SEPAR) Research Group on Diffuse Pulmonary Diseases.
Topics: Acetylcysteine; Biopsy; Bronchoalveolar Lavage Fluid; Cell- and Tissue-Based Therapy; Clinical Trials as Topic; Contraindications; Diagnostic Imaging; Disease Progression; Evidence-Based Medicine; Gastroesophageal Reflux; Genetic Therapy; Glucocorticoids; Humans; Hypertension, Pulmonary; Idiopathic Pulmonary Fibrosis; Immunologic Factors; Incidence; Indoles; Lung; Lung Transplantation; Oxygen Inhalation Therapy; Palliative Care; Prevalence; Prognosis; Pulmonary Emphysema; Pyridones; Risk Factors; Spain | 2013 |
Galecto Biotech.
Topics: Drug Approval; Drug Industry; Galectin 3; Humans; Idiopathic Pulmonary Fibrosis; Pyridones | 2013 |
Safety and efficacy of pirfenidone in idiopathic pulmonary fibrosis in clinical practice.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Mucin-1; Pulmonary Surfactant-Associated Protein D; Pyridones; Treatment Outcome; Vital Capacity | 2013 |
[Successful resection of lung cancer with idiopathic pulmonary fibrosis treated by pirfenidone during perioperative period].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Carcinoma, Squamous Cell; Combined Modality Therapy; Humans; Idiopathic Pulmonary Fibrosis; Lung Neoplasms; Male; Perioperative Period; Pyridones | 2013 |
Possible involvement of pirfenidone metabolites in the antifibrotic action of a therapy for idiopathic pulmonary fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Collagen; Fibroblasts; Humans; Hydroxyproline; Idiopathic Pulmonary Fibrosis; Lung; Pyridones; Transforming Growth Factor beta1 | 2013 |
Idiopathic pulmonary fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Diagnosis, Differential; Humans; Idiopathic Pulmonary Fibrosis; Practice Guidelines as Topic; Pyridones; Treatment Outcome | 2013 |
Combination therapies targeting multiple pathways in idiopathic pulmonary fibrosis (IPF).
Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Drug Therapy, Combination; Free Radical Scavengers; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Vital Capacity | 2013 |
Efficacy of pirfenidone in patients with advanced-stage idiopathic pulmonary fibrosis.
Topics: Acetylcysteine; Administration, Inhalation; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Disease Progression; Drug Therapy, Combination; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones; Retrospective Studies; Treatment Outcome; Vital Capacity | 2013 |
Real world experiences: pirfenidone is well tolerated in patients with idiopathic pulmonary fibrosis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Medication Adherence; Middle Aged; Pyridones; Retrospective Studies; Treatment Outcome; Vital Capacity | 2014 |
NICE guidance on pirfenidone for treating idiopathic pulmonary fibrosis.
Topics: Antineoplastic Agents; Disease Progression; Humans; Idiopathic Pulmonary Fibrosis; Practice Guidelines as Topic; Product Surveillance, Postmarketing; Pyridones; State Medicine; United Kingdom; Vital Capacity | 2013 |
All-cause mortality rate in patients with idiopathic pulmonary fibrosis. Implications for the design and execution of clinical trials.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cause of Death; Clinical Trials, Phase III as Topic; Feasibility Studies; Female; Follow-Up Studies; Humans; Idiopathic Pulmonary Fibrosis; Interferon-gamma; Kaplan-Meier Estimate; Male; Middle Aged; Models, Statistical; Pyridones; Randomized Controlled Trials as Topic; Recombinant Proteins; Research Design; Sample Size; Treatment Outcome | 2014 |
Evolvement of best practice in diagnosis and management of idiopathic pulmonary fibrosis.
Topics: Clinical Trials, Phase III as Topic; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Randomized Controlled Trials as Topic; Respiratory System Agents | 2014 |
Predictors of the clinical effects of pirfenidone on idiopathic pulmonary fibrosis.
Topics: Aged; Anorexia; Anti-Inflammatory Agents, Non-Steroidal; Female; Histamine H2 Antagonists; Humans; Idiopathic Pulmonary Fibrosis; Logistic Models; Male; Middle Aged; Nausea; Predictive Value of Tests; Proportional Hazards Models; Proton Pump Inhibitors; Pyridones; Retrospective Studies; Severity of Illness Index; Survival Rate; Time Factors; Treatment Outcome; Vital Capacity | 2014 |
A new hope for idiopathic pulmonary fibrosis.
Topics: Antifibrinolytic Agents; Enzyme Inhibitors; Female; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Male; Protein Kinase Inhibitors; Pyridones | 2014 |
Management of idiopathic pulmonary fibrosis: selected case reports.
Topics: Aged; Anti-Inflammatory Agents; Disease Progression; Fatal Outcome; Female; Humans; Idiopathic Pulmonary Fibrosis; Lung; Male; Middle Aged; Predictive Value of Tests; Pyridones; Recovery of Function; Respiratory Function Tests; Risk Factors; Smoking; Smoking Cessation; Time Factors; Tomography, X-Ray Computed; Treatment Outcome | 2014 |
InterMune and Boehringer blaze trails for idiopathic pulmonary fibrosis drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Drug Industry; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Treatment Outcome; Tumor Necrosis Factor-alpha | 2014 |
Hot off the breath: A big step forward for idiopathic pulmonary fibrosis.
Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Enzyme Inhibitors; Free Radical Scavengers; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Randomized Controlled Trials as Topic | 2014 |
Pirfenidone in idiopathic pulmonary fibrosis: real-life experience from a German tertiary referral center for interstitial lung diseases.
Topics: Acetylcysteine; Adrenal Cortex Hormones; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Disease Progression; Drug Eruptions; Drug Therapy, Combination; Expectorants; Fatigue; Female; Gastrointestinal Diseases; Germany; Humans; Idiopathic Pulmonary Fibrosis; Male; Medication Adherence; Middle Aged; Pyridones; Retrospective Studies; Tertiary Care Centers; Treatment Outcome; Vital Capacity; Weight Loss | 2014 |
2014 American Thoracic Society International Conference.
Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humanized; Asthma; Congresses as Topic; Eosinophilia; Expectorants; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Idiopathic Pulmonary Fibrosis; Indoles; Lung Neoplasms; Protein Kinase Inhibitors; Pulmonary Disease, Chronic Obstructive; Pyridones; Respiratory Distress Syndrome | 2014 |
[Idiopathic pulmonary fibrosis: A new era, new challenges].
Topics: Acetylcysteine; Clinical Trials as Topic; Free Radical Scavengers; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones | 2014 |
Landmark approvals in idiopathic pulmonary fibrosis.
Topics: Drug Approval; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; United States; United States Food and Drug Administration | 2014 |
Experience with perioperative pirfenidone for lung cancer surgery in patients with idiopathic pulmonary fibrosis.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Disease Progression; Feasibility Studies; Female; Humans; Idiopathic Pulmonary Fibrosis; Lung Neoplasms; Male; Middle Aged; Perioperative Care; Postoperative Complications; Pyridones; Retrospective Studies; Treatment Outcome | 2015 |
A new era of drug therapy for idiopathic pulmonary fibrosis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Middle Aged; Pyridones; Randomized Controlled Trials as Topic | 2014 |
Pharmacokinetic evaluation of tissue distribution of pirfenidone and its metabolites for idiopathic pulmonary fibrosis therapy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cell Membrane Permeability; Idiopathic Pulmonary Fibrosis; Kidney; Liver; Lung; Male; Pyridones; Rats; Tissue Distribution | 2015 |
Efficacy of combined corticosteroid and pirfenidone for acute exacerbation of idiopathic pulmonary fibrosis after surgery for lung cancer: a case report.
Topics: Acute-Phase Reaction; Aged, 80 and over; Disease Progression; Drug Therapy, Combination; Glucocorticoids; Humans; Idiopathic Pulmonary Fibrosis; Infusions, Intravenous; Lung Neoplasms; Male; Methylprednisolone; Postoperative Complications; Prednisolone; Pulse Therapy, Drug; Pyridones; Treatment Outcome | 2015 |
Intraindividual response to treatment with pirfenidone in idiopathic pulmonary fibrosis.
Topics: Administration, Oral; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antifibrinolytic Agents; Female; Germany; Humans; Idiopathic Pulmonary Fibrosis; Italy; Male; Middle Aged; Pyridones; Retrospective Studies; Total Lung Capacity; Treatment Outcome; Vital Capacity | 2015 |
Novel treatments for idiopathic pulmonary fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Enzyme Inhibitors; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Protein-Tyrosine Kinases; Pyridones | 2015 |
Nintedanib and pirfenidone. New antifibrotic treatments indicated for idiopathic pulmonary fibrosis offer hopes and raises questions.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Enzyme Inhibitors; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Treatment Outcome | 2015 |
Update in diffuse parenchymal lung disease, 2013.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials, Phase III as Topic; Disease Progression; Drug Approval; Enzyme Inhibitors; Genomics; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung Diseases, Interstitial; Polymorphism, Genetic; Pyridones; Treatment Outcome; United States; United States Food and Drug Administration | 2015 |
Effectiveness of combined therapy with pirfenidone and inhaled N-acetylcysteine for advanced idiopathic pulmonary fibrosis: a case-control study.
Topics: Acetylcysteine; Administration, Inhalation; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Free Radical Scavengers; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones; Retrospective Studies; Treatment Outcome; Vital Capacity | 2015 |
[Two drugs inhibit disease progression. Idiopathic lung fibrosis treatable for the first time].
Topics: Acetylcysteine; Disease Progression; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Randomized Controlled Trials as Topic; Survival Analysis; Vital Capacity | 2015 |
Efficient delivery to human lung fibroblasts (WI-38) of pirfenidone incorporated into liposomes modified with truncated basic fibroblast growth factor and its inhibitory effect on collagen synthesis in idiopathic pulmonary fibrosis.
Topics: Cell Line; Cell Proliferation; Collagen; Fibroblast Growth Factors; Fibroblasts; HEK293 Cells; Humans; Idiopathic Pulmonary Fibrosis; Liposomes; Lung; Pyridones | 2015 |
Forced vital capacity in idiopathic pulmonary fibrosis--FDA review of pirfenidone and nintedanib.
Topics: Advisory Committees; Anti-Inflammatory Agents, Non-Steroidal; Cause of Death; Drug Approval; Enzyme Inhibitors; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; United States; United States Food and Drug Administration; Vital Capacity | 2015 |
[What is new in 2014 for the specialist in hospital internal medicine? The point of view of university hospital chief residents].
Topics: Alzheimer Disease; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Arterial Pressure; Catheterization, Central Venous; Diverticulitis; Emergency Service, Hospital; Hospitals, University; Humans; Hypertension; Idiopathic Pulmonary Fibrosis; Internal Medicine; Kidney; Medical Staff, Hospital; Pneumonia; Pulmonary Embolism; Pyridones; Shock, Septic; Sympathectomy; Tumor Necrosis Factor-alpha; Ultrasonography; Venous Thromboembolism; Vitamin B 12 Deficiency; Vitamin E | 2015 |
Management of patients with idiopathic pulmonary fibrosis in clinical practice: the INSIGHTS-IPF registry.
Topics: Acetylcysteine; Aged; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Exercise Test; Female; Germany; Humans; Idiopathic Pulmonary Fibrosis; Lung; Male; Middle Aged; Practice Guidelines as Topic; Prospective Studies; Pyridones; Registries; Steroids; Tomography, X-Ray Computed; Vital Capacity | 2015 |
A combined therapeutic approach in progressive idiopathic pulmonary fibrosis-pirfenidone as bridge therapy for ex vivo lung transplantation: a case report.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Combined Modality Therapy; Disease Progression; Humans; Idiopathic Pulmonary Fibrosis; Lung Transplantation; Male; Middle Aged; Pulmonary Fibrosis; Pyridones; Quality of Life | 2015 |
Two therapies now available for idiopathic pulmonary fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Enzyme Inhibitors; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Vital Capacity | 2014 |
Efficacy of pirfenidone for idiopathic pulmonary fibrosis: An Italian real life study.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; Female; Humans; Idiopathic Pulmonary Fibrosis; Incidence; Italy; Male; Pyridones; Retrospective Studies; Treatment Outcome; Vital Capacity | 2015 |
[Two new drugs for the treatment of idiopathic lung fibrosis: A new therapeutic era!].
Topics: Antineoplastic Agents; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Randomized Controlled Trials as Topic | 2015 |
Visual vs Fully Automatic Histogram-Based Assessment of Idiopathic Pulmonary Fibrosis (IPF) Progression Using Sequential Multidetector Computed Tomography (MDCT).
Topics: Aged; Disease Progression; Female; Humans; Idiopathic Pulmonary Fibrosis; Lung; Male; Middle Aged; Multidetector Computed Tomography; Pyridones; Retrospective Studies; Treatment Outcome | 2015 |
Pirfenidone-induced photoleukomelanoderma in a patient with idiopathic pulmonary fibrosis.
Topics: Aged; Dermatitis, Phototoxic; Humans; Hyperpigmentation; Idiopathic Pulmonary Fibrosis; Male; Pyridones | 2016 |
An Unusual Case of Hypoxemia Improving Overnight in Idiopathic Pulmonary Fibrosis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Diagnosis, Differential; Echocardiography, Transesophageal; Foramen Ovale, Patent; Humans; Hypoxia; Idiopathic Pulmonary Fibrosis; Lung; Male; Pyridones; Septal Occluder Device; Tomography, X-Ray Computed | 2015 |
Developments in the management of idiopathic pulmonary fibrosis.
Topics: Disease Progression; Drug Approval; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Orphan Drug Production; Pyridones; United Kingdom | 2015 |
Early Experience of Pirfenidone in Daily Clinical Practice in Belgium and The Netherlands: a Retrospective Cohort Analysis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Belgium; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Netherlands; Pyridones; Respiratory Function Tests; Retrospective Studies; Smoking; Treatment Outcome; Vital Capacity | 2015 |
IPF, comorbidities and management implications: Patient case 2.
Topics: Arteriosclerosis; Comorbidity; Denmark; Disease Management; Female; Humans; Hypertension, Pulmonary; Idiopathic Pulmonary Fibrosis; Lung Transplantation; Middle Aged; Pyridones; Radiography; Refusal to Treat; Respiratory Function Tests; Severity of Illness Index; Smoking | 2015 |
Challenges in IPF diagnosis, current management and future perspectives: Patient case 1.
Topics: Aged; Dyspnea; Early Diagnosis; Female; Follow-Up Studies; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Respiratory Function Tests; Risk Assessment; Time Factors; Tomography, X-Ray Computed; Treatment Outcome | 2015 |
Challenges in IPF diagnosis, current management and future perspectives: Patient case 2.
Topics: Adrenal Cortex Hormones; Aged; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Eruptions; Follow-Up Studies; Hemoptysis; Humans; Hypertension; Idiopathic Pulmonary Fibrosis; Male; Pyridones; Risk Assessment; Severity of Illness Index; Tachycardia, Supraventricular; Tomography, X-Ray Computed; Treatment Outcome | 2015 |
Missing data in IPF trials: do not let methodological issues undermine a major therapeutic breakthrough.
Topics: Clinical Trials, Phase III as Topic; Data Collection; Data Interpretation, Statistical; Female; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Male; Pyridones; Randomized Controlled Trials as Topic; Respiratory Function Tests; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Survival Rate; Treatment Outcome; Vital Capacity | 2015 |
Switching to nintedanib after discontinuation of pirfenidone due to adverse events in IPF.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Body Mass Index; Compassionate Use Trials; Enzyme Inhibitors; Female; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Male; Middle Aged; Pyridones; Respiratory Function Tests; Retrospective Studies; Vital Capacity | 2015 |
All-case post-marketing surveillance of 1371 patients treated with pirfenidone for idiopathic pulmonary fibrosis.
Topics: Aged; Disease Progression; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Product Surveillance, Postmarketing; Prospective Studies; Pyridones; Severity of Illness Index; Treatment Outcome; Vital Capacity | 2015 |
New guideline on treatment of idiopathic pulmonary fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Enzyme Inhibitors; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Practice Guidelines as Topic; Pyridones | 2015 |
[Idiopathic Pulmonary Fibrosis].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Evidence-Based Medicine; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Respiratory System Agents; Treatment Outcome | 2015 |
Therapeutic advances in idiopathic pulmonary fibrosis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Enzyme Inhibitors; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones | 2016 |
Risk factors for acute exacerbation of idiopathic pulmonary fibrosis--Extended analysis of pirfenidone trial in Japan.
Topics: Acute Disease; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials, Phase III as Topic; Disease Progression; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Multivariate Analysis; Oxygen Consumption; Proportional Hazards Models; Pulmonary Alveoli; Pyridones; Risk Factors; Vital Capacity | 2015 |
Efficacy of pirfenidone and disease severity of idiopathic pulmonary fibrosis: Extended analysis of phase III trial in Japan.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials, Phase III as Topic; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Oxygen Consumption; Pyridones; Retrospective Studies; Severity of Illness Index; Survival Rate; Treatment Outcome; Vital Capacity; Young Adult | 2015 |
Levels of circulating endothelial cells are low in idiopathic pulmonary fibrosis and are further reduced by anti-fibrotic treatments.
Topics: Aged; Aged, 80 and over; Biomarkers; Disease Progression; Endothelial Cells; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Pyridones; Vascular Endothelial Growth Factor A | 2015 |
Composite Physiologic Index, Percent Forced Vital Capacity and Percent Diffusing Capacity for Carbon Monoxide Could Be Predictors of Pirfenidone Tolerability in Patients with Idiopathic Pulmonary Fibrosis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Carbon Monoxide; Disease Progression; Dose-Response Relationship, Drug; Female; Humans; Idiopathic Pulmonary Fibrosis; Lung; Male; Middle Aged; Predictive Value of Tests; Pyridones; Retrospective Studies; Treatment Outcome; Vital Capacity | 2015 |
"The Long and Winding Road" seeking specific drugs for idiopathic pulmonary fibrosis.
Topics: Clinical Trials as Topic; Drug Discovery; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Japan; Pyridones; United States | 2016 |
Qualitative European survey of patients with idiopathic pulmonary fibrosis: patients' perspectives of the disease and treatment.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Attitude to Health; Caregivers; Disease Management; Europe; Female; Germany; Health Services Needs and Demand; Humans; Idiopathic Pulmonary Fibrosis; Italy; Male; Nurse's Role; Physician's Role; Pyridones; Qualitative Research; Role; Surveys and Questionnaires; United Kingdom | 2016 |
Idiopathic pulmonary fibrosis: the role of the pharmacy benefit manager in providing access to effective, high-value care.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Disease Management; Drug Costs; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Insurance, Pharmaceutical Services; Pharmacies; Pyridones; United States | 2015 |
Pirfenidone and nintedanib modulate properties of fibroblasts and myofibroblasts in idiopathic pulmonary fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fibroblasts; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Myofibroblasts; Pyridones; Treatment Outcome | 2016 |
Clinical Experience of the Long-term Use of Pirfenidone for Idiopathic Pulmonary Fibrosis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; Dose-Response Relationship, Drug; Female; Humans; Idiopathic Pulmonary Fibrosis; Japan; Male; Pyridones; Retrospective Studies; Time Factors; Treatment Outcome; Vital Capacity | 2016 |
A Patient with Idiopathic Pleuroparenchymal Fibroelastosis Showing a Sustained Pulmonary Function due to Treatment with Pirfenidone.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Dyspnea; Humans; Idiopathic Pulmonary Fibrosis; Lung; Male; Pleural Diseases; Pyridones; Radiography, Thoracic; Respiratory Physiological Phenomena; Time Factors; Treatment Outcome; Vital Capacity; Weight Loss | 2016 |
Administration of nintedanib after discontinuation for acute exacerbation of idiopathic pulmonary fibrosis: a case report.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; Drug Therapy, Combination; Enzyme Inhibitors; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung; Male; Middle Aged; Pyridones; Tomography, X-Ray Computed; Vital Capacity | 2016 |
Marked Improvement with Pirfenidone in a Patient with Idiopathic Pulmonary Fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cough; Disease Progression; Dyspnea; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones; Tomography, X-Ray Computed; Treatment Outcome; Vital Capacity | 2016 |
Successful Concomitant Therapy with Pirfenidone and Nintedanib in Idiopathic Pulmonary Fibrosis: A Case Report.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Drug Therapy, Combination; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Male; Pyridones; Vital Capacity | 2016 |
Idiopathic Pulmonary Fibrosis and the Elderly: Diagnosis and Management Considerations.
Topics: Aged; Aged, 80 and over; Aging; Antineoplastic Agents; Biopsy; Comorbidity; Disease Management; Disease Progression; Female; Humans; Idiopathic Pulmonary Fibrosis; Incidence; Indoles; Male; Pyridones; Tomography, X-Ray Computed | 2016 |
MAP3K19 Is a Novel Regulator of TGF-β Signaling That Impacts Bleomycin-Induced Lung Injury and Pulmonary Fibrosis.
Topics: A549 Cells; Animals; Bleomycin; Bronchoalveolar Lavage; Cell Line, Tumor; Disease Models, Animal; Epithelial Cells; Female; HeLa Cells; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung; Lung Injury; MAP Kinase Kinase Kinases; Mice; Mice, Inbred C57BL; Pulmonary Fibrosis; Pyridones; Signal Transduction; Transforming Growth Factor beta; Up-Regulation | 2016 |
Raised serum levels of IGFBP-1 and IGFBP-2 in idiopathic pulmonary fibrosis.
Topics: Aged; Aged, 80 and over; Belgium; Biomarkers; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Female; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Insulin-Like Growth Factor Binding Protein 1; Insulin-Like Growth Factor Binding Protein 2; Male; Middle Aged; Mucin-1; Prospective Studies; Pyridones | 2016 |
[Idiopatic pulmonary fibrosis - news in multidisciplinary diagnostic and therapeutic approaches].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diagnosis, Differential; Humans; Idiopathic Pulmonary Fibrosis; Prognosis; Pyridones | 2016 |
Pirfenidone inhibits p38-mediated generation of procoagulant microparticles by human alveolar epithelial cells.
Topics: A549 Cells; Alveolar Epithelial Cells; Cell-Derived Microparticles; Humans; Hydrogen Peroxide; Idiopathic Pulmonary Fibrosis; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridones | 2016 |
Pirfenidone for Idiopathic Pulmonary Fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Treatment Outcome; Vital Capacity | 2016 |
COUNTERPOINT: Should All Patients With Idiopathic Pulmonary Fibrosis, Even Those With More Than Moderate Impairment, Be Treated With Nintedanib or Pirfenidone? No.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Decision Making; Drug Tolerance; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Severity of Illness Index; Tumor Necrosis Factor-alpha | 2016 |
POINT: Should All Patients With Idiopathic Pulmonary Fibrosis, Even Those With More Than Moderate Impairment, Be Treated With Nintedanib or Pirfenidone? Yes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Decision Making; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Severity of Illness Index; Tumor Necrosis Factor-alpha | 2016 |
Pulmonary fibrolysis in a patient with idiopathic pulmonary fibrosis: improvement of clinical and radiological pattern after treatment with pirfenidone.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Diagnosis, Differential; Humans; Idiopathic Pulmonary Fibrosis; Lung; Male; Pyridones; Tomography, X-Ray Computed | 2018 |
Eosinophilic pneumonia associated with pirfenidone therapy.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Computed Tomography Angiography; Humans; Idiopathic Pulmonary Fibrosis; Lung; Male; Pulmonary Eosinophilia; Pyridones; Tomography, X-Ray Computed | 2016 |
Severe Colitis Associated with Pirfenidone Use in Idiopathic Pulmonary Fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Colitis; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones | 2016 |
Effect of Perioperative Pirfenidone Treatment in Lung Cancer Patients With Idiopathic Pulmonary Fibrosis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; Drug Administration Schedule; Drug Evaluation; Female; Humans; Idiopathic Pulmonary Fibrosis; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Perioperative Care; Pneumonectomy; Postoperative Complications; Pyridones; Retrospective Studies; Risk Assessment; Risk Factors; Smoking | 2016 |
Upregulation of RGS2: a new mechanism for pirfenidone amelioration of pulmonary fibrosis.
Topics: Animals; Bleomycin; Calcium Signaling; Cell Line; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression Profiling; Humans; Idiopathic Pulmonary Fibrosis; Lung; Mice, Inbred C57BL; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Pyridones; RGS Proteins; RNA, Messenger; Thrombin; Time Factors; Transfection; Up-Regulation | 2016 |
Respiratory Conditions Update: Restrictive Lung Disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Continuous Positive Airway Pressure; Disease Progression; Enzyme Inhibitors; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Obesity Hypoventilation Syndrome; Oxygen Inhalation Therapy; Polysomnography; Pyridones; Respiratory Function Tests; Respiratory Therapy; Sleep Apnea, Obstructive; Weight Loss | 2016 |
Role of Pirfenidone in Idiopathic Pulmonary Fibrosis - A Longitudinal Cohort Study.
Topics: Acetylcysteine; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Cohort Studies; Drug Therapy, Combination; Female; Humans; Idiopathic Pulmonary Fibrosis; Longitudinal Studies; Male; Middle Aged; Proton Pump Inhibitors; Pyridones; Treatment Outcome | 2016 |
Assessing the Therapeutic Response to Pirfenidone in Idiopathic Pulmonary Fibrosis: Can We Do Better than with Forced Vital Capacity Alone?
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Disease-Free Survival; Dyspnea; Female; Forced Expiratory Volume; Humans; Idiopathic Pulmonary Fibrosis; Longitudinal Studies; Male; Middle Aged; Pilot Projects; Prospective Studies; Pulmonary Diffusing Capacity; Pyridones; Treatment Outcome; Vital Capacity; Walk Test | 2017 |
Safety and efficacy of bridging to lung transplantation with antifibrotic drugs in idiopathic pulmonary fibrosis: a case series.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Belgium; Disease Progression; Female; Graft Survival; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung; Lung Transplantation; Male; Middle Aged; Postoperative Complications; Pyridones; Retrospective Studies; Tertiary Care Centers; Vital Capacity | 2016 |
Pirfenidone and mortality in idiopathic pulmonary fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Treatment Outcome; Vital Capacity | 2017 |
Effects and mechanisms of pirfenidone, prednisone and acetylcysteine on pulmonary fibrosis in rat idiopathic pulmonary fibrosis models.
Topics: Acetylcysteine; Animals; Bleomycin; Blotting, Western; Caveolin 1; Cytoprotection; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Idiopathic Pulmonary Fibrosis; Lung; Male; Platelet-Derived Growth Factor; Prednisone; Protective Agents; Pyridones; Rats, Wistar; Real-Time Polymerase Chain Reaction; Signal Transduction; Time Factors; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2017 |
Prognostic value of serial serum KL-6 measurements in patients with idiopathic pulmonary fibrosis.
Topics: Aged; Aged, 80 and over; Biomarkers; Female; Follow-Up Studies; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Mucin-1; Prognosis; Pyridones; Retrospective Studies | 2017 |
3D pulmospheres serve as a personalized and predictive multicellular model for assessment of antifibrotic drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Case-Control Studies; Disease Progression; Enzyme Inhibitors; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung; Models, Biological; Myofibroblasts; Precision Medicine; Pyridones; Spheroids, Cellular; Transforming Growth Factor beta1 | 2017 |
Pirfenidone exerts antifibrotic effects through inhibition of GLI transcription factors.
Topics: Adult; Aged; Cell Proliferation; Female; Fibroblasts; Hedgehog Proteins; Humans; Idiopathic Pulmonary Fibrosis; Kruppel-Like Transcription Factors; Male; Middle Aged; Nuclear Proteins; Pyridones; Signal Transduction; Transforming Growth Factor beta; Zinc Finger Protein Gli2 | 2017 |
A Novel Antifibrotic Mechanism of Nintedanib and Pirfenidone. Inhibition of Collagen Fibril Assembly.
Topics: Collagen Type I; Down-Regulation; Extracellular Matrix Proteins; Fibrillar Collagens; Fibroblasts; HSP47 Heat-Shock Proteins; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung; Protein Processing, Post-Translational; Pyridones; Tacrolimus Binding Proteins; Transcription, Genetic | 2017 |
Pirfenidone-induced photo-allergic reaction in a patient with idiopathic pulmonary fibrosis.
Topics: Aged; Dermatitis, Photoallergic; Drug Hypersensitivity; Humans; Idiopathic Pulmonary Fibrosis; Male; Pyridones | 2017 |
Improving Survival in Idiopathic Pulmonary Fibrosis: The Race Has Just Begun.
Topics: Antineoplastic Agents; Clinical Trials as Topic; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Survival Analysis; Tumor Necrosis Factor-alpha | 2017 |
Guidelines for the medical treatment of idiopathic pulmonary fibrosis.
Topics: Adrenal Cortex Hormones; Disease Progression; Disease-Free Survival; Evidence-Based Medicine; Gastroesophageal Reflux; Gastrointestinal Diseases; Humans; Hypertension, Pulmonary; Idiopathic Pulmonary Fibrosis; Indoles; Meta-Analysis as Topic; Pulmonary Emphysema; Pyridones; Randomized Controlled Trials as Topic; Societies, Medical; Spain | 2017 |
Permutation test following covariate-adaptive randomization in randomized controlled trials.
Topics: Algorithms; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Computer Simulation; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Models, Statistical; Monte Carlo Method; Pyridones; Randomized Controlled Trials as Topic; Treatment Outcome; Vital Capacity | 2009 |
[Pharmacological properties and clinical effects of the antifibrotic agent pirfenidone (Pirespa) for treatment of idiopathic pulmonary fibrosis].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Gastrointestinal Diseases; Humans; Idiopathic Pulmonary Fibrosis; Photosensitivity Disorders; Pyridones; Skin Neoplasms | 2009 |
Idiopathic pulmonary fibrosis and pirfenidone.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Randomized Controlled Trials as Topic | 2010 |
FDA panel likes new treatment for idiopathic pulmonary fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; United States; United States Food and Drug Administration | 2010 |
Pirfenidone in idiopathic pulmonary fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Follow-Up Studies; Humans; Idiopathic Pulmonary Fibrosis; Longitudinal Studies; Pyridones; Research Design; Time Factors; Treatment Outcome | 2010 |
Pirfenidone for idiopathic pulmonary fibrosis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials, Phase III as Topic; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Approval; Endpoint Determination; Europe; Evidence-Based Medicine; Exercise Test; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Randomized Controlled Trials as Topic; Vital Capacity | 2011 |
Pirfenidone.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Drug Approval; Drug Discovery; Humans; Idiopathic Pulmonary Fibrosis; Pyridones | 2011 |
A first step against idiopathic pulmonary fibrosis.
Topics: Clinical Trials as Topic; Evidence-Based Medicine; Humans; Idiopathic Pulmonary Fibrosis; Lung; Pyridones; Respiratory System Agents; Treatment Outcome | 2011 |
Idiopathic pulmonary fibrosis: recent milestones in disease management.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Disease Management; Humans; Idiopathic Pulmonary Fibrosis; Pyridones | 2012 |
Treating idiopathic pulmonary fibrosis: current opportunities and future challenges.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Discovery; Humans; Idiopathic Pulmonary Fibrosis; Pyridones | 2012 |
Pirfenidone treatment in idiopathic pulmonary fibrosis: too much of a great expectation?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Humans; Idiopathic Pulmonary Fibrosis; Lung; Pyridones; Respiratory Function Tests | 2012 |