Page last updated: 2024-08-23

pirfenidone and Cicatrix

pirfenidone has been researched along with Cicatrix in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (53.33)24.3611
2020's7 (46.67)2.80

Authors

AuthorsStudies
Astrakhantsev, AF; Atkova, EL; Fedorov, AA; Krakhovetskiy, NN; Rein, DA1
Gao, B; Li, X; Ma, Y; Pan, J; Qian, H1
Ale, T; Kehinde, V; Lavik, E; Liu, S; Wang, HC1
Aimo, A; Aquaro, GD; Barison, A; Burchielli, S; Emdin, M; Masotti, S; Modena, M; Musetti, V; Passino, C; Pucci, A; Terlizzi, D1
Chen, J; Huang, Y; Lu, C; Mei, L; Pan, X; Peng, T; Quan, G; Wang, B; Wang, H; Wu, C1
Barrett, VJ; Brockbank, S; Cruwys, S; Dabbagh, RQ; Genovese, F; Good, RB; Jessen, H; Karsdal, MA; Leeming, DJ; Nanthakumar, CB; Rønnow, SR; Sand, JMB; Sorensen, GL1
Furushima, S; Kodama, H; Kumai, Y; Miyamaru, S; Nishimoto, K; Toya, Y; Yumoto, E1
DeLuca, PP; Dorati, R; Leung, KP; Medina, JL1
Dorati, R; Fourcaudot, AB; Leung, KP; Medina, JL; Sebastian, EA1
Chen, J; Coleman, JA; Durack, JC; Felsen, D; Fujimori, M; Kodama, H; Solomon, SB; Srimathveeravalli, G; Ueshima, E1
Kodama, H; Kumai, Y; Miyamaru, S; Nishimoto, K; Onoue, S; Orita, Y; Yamada, T1
Leask, A1
Jung, KI; Park, CK1
Hayden, T1
Lin, X; Sun, G; Wu, K; Yu, M; Zhong, H1

Reviews

1 review(s) available for pirfenidone and Cicatrix

ArticleYear
Getting to the heart of the matter: new insights into cardiac fibrosis.
    Circulation research, 2015, Mar-27, Volume: 116, Issue:7

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agents; Arrhythmias, Cardiac; Atrophy; Cicatrix; Connective Tissue Growth Factor; Endothelin Receptor Antagonists; Endothelin-1; Fibrosis; Humans; Hypoxia; Models, Cardiovascular; Molecular Targeted Therapy; Myocardium; Myofibroblasts; Platelet-Derived Growth Factor; Pyridones; Rats; Signal Transduction; Transforming Growth Factor beta

2015

Trials

1 trial(s) available for pirfenidone and Cicatrix

ArticleYear
Effects of pirfenidone on scar size and ventricular remodeling after myocardial infarction: a preclinical study.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2023, 12-01, Volume: 24, Issue:12

    Topics: Animals; Cicatrix; Fibrosis; Humans; Male; Myocardial Infarction; Rats; Rats, Wistar; Ventricular Remodeling

2023

Other Studies

13 other study(ies) available for pirfenidone and Cicatrix

ArticleYear
[Experimental investigation of the efficacy of pirfenidone in prevention of ostium cicatricial closure after dacryocystorhinostomy].
    Vestnik oftalmologii, 2021, Volume: 137, Issue:5

    Topics: Animals; Cicatrix; Dacryocystorhinostomy; Endoscopy; Nasolacrimal Duct; Pyridones; Rabbits; Treatment Outcome

2021
Treatment of scarring central airway stenosis with pirfenidone: Case report.
    Medicine, 2022, Oct-28, Volume: 101, Issue:43

    Topics: Bronchi; Bronchoscopy; Cicatrix; Constriction, Pathologic; Humans; Stents; Tomography, X-Ray Computed; Trachea

2022
Polyester Nanoparticles and Polyurethane Nanocapsules Deliver Pirfenidone To Reduce Fibrosis and Scarring.
    ACS biomaterials science & engineering, 2023, 06-12, Volume: 9, Issue:6

    Topics: Cicatrix; Humans; Inflammation; Nanocapsules; Nanoparticles; Polyesters; Polylactic Acid-Polyglycolic Acid Copolymer; Polyurethanes

2023
A pirfenidone loaded spray dressing based on lyotropic liquid crystals for deep partial thickness burn treatment: healing promotion and scar prophylaxis.
    Journal of materials chemistry. B, 2020, 04-01, Volume: 8, Issue:13

    Topics: Animals; Antifibrinolytic Agents; Bandages; Burns; Cells, Cultured; Cicatrix; Disease Models, Animal; Humans; Liquid Crystals; Male; Mice; Mice, Inbred BALB C; Particle Size; Pyridones; Surface Properties; Wound Healing

2020
Prolonged Scar-in-a-Jar: an in vitro screening tool for anti-fibrotic therapies using biomarkers of extracellular matrix synthesis.
    Respiratory research, 2020, May-07, Volume: 21, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Cells, Cultured; Cicatrix; Collagen; Drug Evaluation, Preclinical; Extracellular Matrix; Fibroblasts; Fibronectins; Fibrosis; Humans; Indoles; Protein Kinase Inhibitors; Pyridones; Transforming Growth Factor beta1

2020
Potential treatment for vocal fold scar with pirfenidone.
    The Laryngoscope, 2018, Volume: 128, Issue:5

    Topics: Actins; Animals; Cells, Cultured; Cicatrix; Collagen Type I; Ferrets; Fibroblasts; Hyaluronan Synthases; Pyridones; Real-Time Polymerase Chain Reaction; Transforming Growth Factor beta1; Vocal Cords

2018
Development of a Topical 48-H Release Formulation as an Anti-scarring Treatment for Deep Partial-Thickness Burns.
    AAPS PharmSciTech, 2018, Volume: 19, Issue:5

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Burns; Cicatrix; Delayed-Action Preparations; Drug Liberation; Male; Mice; Mice, Inbred C57BL; Ointments; Pyridones; Treatment Outcome; Tumor Necrosis Factor-alpha; Wound Healing

2018
Pirfenidone Ointment Modulates the Burn Wound Bed in C57BL/6 Mice by Suppressing Inflammatory Responses.
    Inflammation, 2019, Volume: 42, Issue:1

    Topics: Actins; Animals; Burns; Cicatrix; Cytokines; Hydroxyproline; Inflammation; Mice; Mice, Inbred C57BL; Pyridones

2019
Macrophage-secreted TGF-β
    American journal of physiology. Renal physiology, 2019, 07-01, Volume: 317, Issue:7

    Topics: Animals; BALB 3T3 Cells; Cicatrix; Collagen; Constriction, Pathologic; Female; Fibroblasts; Macrophages; Mice; Models, Animal; Pyridones; RAW 264.7 Cells; Sus scrofa; Transforming Growth Factor beta1; Ureter; Ureteral Diseases; Wound Healing

2019
Effect of pirfenidone injection on ferret vocal fold scars: A preliminary in vivo study.
    The Laryngoscope, 2020, Volume: 130, Issue:3

    Topics: Animals; Cicatrix; Ferrets; Injections, Intralesional; Laryngeal Diseases; Male; Pyridones; Vocal Cords

2020
Pirfenidone inhibits fibrosis in foreign body reaction after glaucoma drainage device implantation.
    Drug design, development and therapy, 2016, Volume: 10

    Topics: Animals; Cicatrix; Disease Models, Animal; Fibrosis; Foreign-Body Reaction; Glaucoma Drainage Implants; Pyridones; Rabbits; Wound Healing

2016
Scarred by disease.
    Nature medicine, 2011, Volume: 17, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cicatrix; Collagen; Fibrosis; Humans; Pyridones; Skin; United States; United States Food and Drug Administration

2011
Evaluation of pirfenidone as a new postoperative antiscarring agent in experimental glaucoma surgery.
    Investigative ophthalmology & visual science, 2011, May-16, Volume: 52, Issue:6

    Topics: Actins; Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Movement; Cell Proliferation; Cicatrix; Collagen; Conjunctival Diseases; Disease Models, Animal; Drug Evaluation; Endothelium, Corneal; Glaucoma; Intraocular Pressure; Mitomycin; Ophthalmic Solutions; Postoperative Complications; Proliferating Cell Nuclear Antigen; Pyridones; Rabbits; Trabeculectomy; Tumor Necrosis Factor-alpha

2011