Page last updated: 2024-08-23

pirfenidone and Chronic Lung Injury

pirfenidone has been researched along with Chronic Lung Injury in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (50.00)24.3611
2020's4 (50.00)2.80

Authors

AuthorsStudies
Cao, R; Chen, C; Kang, M; Li, Z; Liao, S; Xu, B; Xue, D; Yang, Y; Zeng, B1
Aoyama, J; Gemma, A; Kamio, K; Matsuda, K; Saito, Y; Seike, M; Tanaka, T1
Hamidi, SH; Kadamboor Veethil, S1
Chen, M; Chen, Y; Fang, M; Hang, QQ; Qian, X; Ying, H1
Hasegawa, Y; Hashimoto, N; Ito, S; Sakamoto, K1
Ghazi-Khansari, M; Heidari, MR; Iranpour, M; Mandegary, A; Pourgholamhossein, F; Pourgholi, L; Pournamdari, M; Poursalehi, HR; Rasooli, R; Samareh-Fekri, M1
Chen-Yoshikawa, TF; Date, H; Masuda, S; Okabe, R; Saito, M; Suetsugu, K; Takahagi, A1
Bacon, KB; Boehme, SA; DiTirro, DN; Franz-Bacon, K; Ly, TW1

Reviews

1 review(s) available for pirfenidone and Chronic Lung Injury

ArticleYear
Role of pirfenidone in TGF-β pathways and other inflammatory pathways in acute respiratory syndrome coronavirus 2 (SARS-Cov-2) infection: a theoretical perspective.
    Pharmacological reports : PR, 2021, Volume: 73, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; COVID-19; COVID-19 Drug Treatment; Humans; Inflammation; Lung Injury; Pyridones; SARS-CoV-2; Signal Transduction; Transforming Growth Factor beta

2021

Trials

1 trial(s) available for pirfenidone and Chronic Lung Injury

ArticleYear
Pirfenidone for the prevention of radiation-induced lung injury in patients with locally advanced oesophageal squamous cell carcinoma: a protocol for a randomised controlled trial.
    BMJ open, 2022, 10-27, Volume: 12, Issue:10

    Topics: Clinical Trials, Phase II as Topic; Cytokines; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Humans; Lung Injury; Radiation Injuries; Randomized Controlled Trials as Topic

2022

Other Studies

6 other study(ies) available for pirfenidone and Chronic Lung Injury

ArticleYear
Increased CTGF expression in alveolar epithelial cells by cyclic mechanical stretch: Its mechanism and the therapeutic effect of pirfenidone.
    Respiratory physiology & neurobiology, 2023, Volume: 317

    Topics: Alveolar Epithelial Cells; Animals; Connective Tissue Growth Factor; Cytokines; Humans; Lung Injury; Mice; Mitogen-Activated Protein Kinase Kinases

2023
Pirfenidone modulates macrophage polarization and ameliorates radiation-induced lung fibrosis by inhibiting the TGF-β1/Smad3 pathway.
    Journal of cellular and molecular medicine, 2021, Volume: 25, Issue:18

    Topics: Animals; Bone Marrow Cells; Female; Fibrosis; Lung Injury; Macrophage Activation; Mice; Mice, Inbred C57BL; Pyridones; RAW 264.7 Cells; Smad3 Protein; Transforming Growth Factor beta1

2021
Pirfenidone as salvage treatment for refractory bleomycin-induced lung injury: a case report of seminoma.
    BMC cancer, 2017, Aug-07, Volume: 17, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antineoplastic; Biomarkers; Bleomycin; Humans; Lung Injury; Male; Middle Aged; Pyridones; Respiratory Function Tests; Seminoma; Tomography, X-Ray Computed; Treatment Outcome

2017
Pirfenidone protects against paraquat-induced lung injury and fibrosis in mice by modulation of inflammation, oxidative stress, and gene expression.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2018, Volume: 112

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Bronchoalveolar Lavage Fluid; Fibrosis; Gene Expression; Gene Expression Profiling; Herbicides; Hydroxyproline; Lung; Lung Injury; Male; Mice; Organ Size; Oxidative Stress; Paraquat; Pneumonia; Pulmonary Fibrosis; Pyridones; Reactive Oxygen Species; Transforming Growth Factor beta1

2018
Pirfenidone alleviates lung ischemia-reperfusion injury in a rat model.
    The Journal of thoracic and cardiovascular surgery, 2019, Volume: 158, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Cytokines; Cytoprotection; Disease Models, Animal; Inflammation Mediators; Lung; Lung Injury; Lung Transplantation; Male; Pyridones; Rats, Wistar; Reperfusion Injury; Signal Transduction; Warm Ischemia

2019
MAP3K19 Is a Novel Regulator of TGF-β Signaling That Impacts Bleomycin-Induced Lung Injury and Pulmonary Fibrosis.
    PloS one, 2016, Volume: 11, Issue:5

    Topics: A549 Cells; Animals; Bleomycin; Bronchoalveolar Lavage; Cell Line, Tumor; Disease Models, Animal; Epithelial Cells; Female; HeLa Cells; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung; Lung Injury; MAP Kinase Kinase Kinases; Mice; Mice, Inbred C57BL; Pulmonary Fibrosis; Pyridones; Signal Transduction; Transforming Growth Factor beta; Up-Regulation

2016