Compounds > pirfenidone
Page last updated: 2024-08-23

pirfenidone and Cardiomegaly

pirfenidone has been researched along with Cardiomegaly in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Cao, Q; Chen, Z; Huang, X; Lai, H; Ouyang, X; Tao, Y; Wang, S; Wang, Y; Yang, L; Zhou, H1
Gao, Y; Han, R; He, J; Kang, L; Li, C; Li, Y; Tian, J; Wang, J1
Hanatani, A; Iwao, H; Izumi, Y; Muro, T; Nakamura, Y; Shimada, K; Shiota, M; Yamashita, N; Yamazaki, T; Yoshiyama, M1

Other Studies

3 other study(ies) available for pirfenidone and Cardiomegaly

ArticleYear
Pirfenidone attenuates cardiac hypertrophy against isoproterenol by inhibiting activation of the janus tyrosine kinase-2/signal transducer and activator of transcription 3 (JAK-2/STAT3) signaling pathway.
    Bioengineered, 2022, Volume: 13, Issue:5

    Topics: Animals; Cardiomegaly; Isoproterenol; Mice; Myocytes, Cardiac; Pyridones; Signal Transduction; STAT3 Transcription Factor; TYK2 Kinase; Tyrosine

2022
Pirfenidone controls the feedback loop of the AT1R/p38 MAPK/renin-angiotensin system axis by regulating liver X receptor-α in myocardial infarction-induced cardiac fibrosis.
    Scientific reports, 2017, 01-16, Volume: 7

    Topics: Angiotensin II; Animals; Cardiomegaly; Collagen Type I; Collagen Type III; Feedback, Physiological; Fibrosis; Hemodynamics; Hydroxyproline; Liver X Receptors; Male; Myocardial Infarction; Myocardium; p38 Mitogen-Activated Protein Kinases; Peptidyl-Dipeptidase A; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridones; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Signal Transduction; Systole; Ventricular Dysfunction

2017
The antifibrotic agent pirfenidone inhibits angiotensin II-induced cardiac hypertrophy in mice.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2012, Volume: 35, Issue:1

    Topics: Angiotensin II; Animals; Blood Pressure; Body Weight; Cardiomegaly; Fibrosis; Heart; Heart Rate; Hypertension; Male; Mice; Mice, Inbred BALB C; Myocardium; Pyridones

2012