Page last updated: 2024-08-23

pirfenidone and Cancer of Lung

pirfenidone has been researched along with Cancer of Lung in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's14 (48.28)24.3611
2020's15 (51.72)2.80

Authors

AuthorsStudies
Ishibashi, F; Mizobuchi, T; Nagato, K; Saiki, A; Sugano, I; Tsuyusaki, J1
Antunes, C; Branco, H; Oliveira, J; Santos, LL; Vasconcelos, MH; Xavier, CPR1
Cao, L; Deng, P; Hu, C; Li, Y; Liu, J; Pan, P; Yang, H1
Cai, M; Chen, J; Chen, Y; Guo, Y; Huang, J; Huang, W; Lai, M; Liang, L; Lin, L; Liu, M; Xie, L; Zhang, X; Zhang, Y; Zhu, K1
Didiasova, M; Drakopanagiotakis, F; Krämer, M; Mamazhakypov, A; Markart, P; Schaefer, L; Wygrecka, M1
Imanishi, N; Kanayama, M; Kuroda, K; Kuwata, T; Matsumiya, H; Mori, M; Shinohara, S; Taira, A; Tanaka, F; Yoneda, K1
Aokage, K; Ishii, G; Miyoshi, T; Sekihara, K; Tane, K; Tsuboi, M1
Boulate, D; Crutu, A; Dauriat, G; Dolidon, S; Fabre, D; Fadel, E; Feuillet, S; Florea, V; Gazengel, P; Hanna, A; Le Pavec, J; Mercier, O; Mitilian, D; Mussot, S; Pradere, P1
Fujiwara, A; Fukui, E; Funaki, S; Kanou, T; Kimura, K; Minami, M; Ose, N; Shintani, Y1
Akazawa, Y; Ishijima, M; Kanazu, M; Kuge, T; Mori, M; Okabe, F; Uenami, T; Yamaguchi, T; Yamamoto, Y; Yano, Y1
Asano, K; Enokida, K; Hattori, S; Hayama, N; Hirabayashi, K; Horio, Y; Ito, Y; Miyaoka, M; Niimi, K; Oguma, T; Ohshinden, K; Takahashi, F; Takahashi, G; Takahashi, M; Takiguchi, H; Takihara, T; Tanaka, J1
Han, H; Huang, Y; Kang, Y; Li, L; Liu, B; Liu, C; Qin, W; Tang, Y; Yuan, X; Zhao, W; Zou, J1
Deng, H; Fang, T; Shen, Q; Xu, Y; Yang, J; Yang, Y; Zhang, J; Zuo, T1
Cheng, X; Han, X; Li, J; Yu, H; Yu, L; Zhang, X1
Miao, K; Tian, X; Xu, W; Xu, Y; Zhang, L; Zhang, Y1
Maeda, S1
Azuma, A; Gemma, A; Inomata, M; Miura, Y; Nei, T; Saito, T; Saito, Y; Takoi, H; Tanaka, T; Yatagai, Y1
Tanino, Y1
Joensuu, E; Koli, K; Li, C; Myllärniemi, M; Rezov, V; Rönty, M; Vartiainen, V; Yin, M1
Azuma, A; Bando, M; Date, H; Ebina, M; Fukuoka, J; Gemma, A; Goto, Y; Hasegawa, Y; Hattori, N; Homma, S; Inase, N; Inoue, Y; Ishii, Y; Izumi, S; Johkoh, T; Kido, T; Kishaba, T; Kishi, K; Miyamoto, A; Mukae, H; Nakayama, T; Nishioka, Y; Ogura, T; Sakamoto, S; Sasaki, S; Suda, T; Sugino, K; Taguchi, Y; Takahashi, H; Takahashi, K; Taniguchi, H; Watanabe, K; Yokoyama, A; Yoshino, I1
Ballester, B; Cortijo, J; Milara, J1
Katayama, Y; Komada, T; Kusagawa, H; Shomura, S1
Kang, S1
Iwata, T; Mizobuchi, T; Nagato, K; Nakajima, T; Nakatani, Y; Ota, S; Suzuki, H; Tagawa, T; Yoshida, S; Yoshino, I1
Kunii, E; Moriyama, S; Niimi, A; Ohkubo, H1
Asato, Y; Azuma, A; Chida, M; Fukuoka, J; Hiroshima, K; Ikeda, N; Iwasawa, T; Iwata, T; Katakami, N; Kuwano, K; Matsuura, M; Mitsudomi, T; Nakagawa, K; Nakanishi, Y; Okada, M; Okami, J; Okubo, K; Sakai, S; Sakamoto, K; Tada, H; Takenoyama, M; Tomii, K; Tsuboi, M; Yamashita, M; Yamashita, Y; Yokouchi, H; Yoshida, S; Yoshimura, K; Yoshino, I1
Fujiwara, T; Iwata, T; Nakajima, T; Suzuki, H; Wada, H; Yoshida, S; Yoshino, I1
Le, A; Takai, K; Weaver, VM; Werb, Z1
Fujiwara, A; Funaki, S; Kawamura, T; Kimura, T; Minami, M; Okumura, M; Shintani, Y1

Reviews

5 review(s) available for pirfenidone and Cancer of Lung

ArticleYear
Lung transplantation for idiopathic pulmonary fibrosis.
    Presse medicale (Paris, France : 1983), 2020, Volume: 49, Issue:2

    Topics: Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Cardiovascular Diseases; Comorbidity; Disease Progression; Frailty; Gastroesophageal Reflux; Humans; Hypertension, Pulmonary; Idiopathic Interstitial Pneumonias; Idiopathic Pulmonary Fibrosis; Indoles; Lung Neoplasms; Lung Transplantation; Prognosis; Pyridones; Telomere Shortening

2020
[A Case Report of Checkpoint Inhibitor Pneumonitis Caused by PD-1
Antibody-Safety and Effectiveness of Pirfenidone].
    Zhongguo fei ai za zhi = Chinese journal of lung cancer, 2021, Jul-20, Volume: 24, Issue:7

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Carcinoma, Squamous Cell; Glucocorticoids; Humans; Immune Checkpoint Inhibitors; Indoles; Lung Neoplasms; Male; Nivolumab; Pneumonia; Programmed Cell Death 1 Receptor; Protein Kinase Inhibitors; Pyridones; Quinolines; Retrospective Studies

2021
[Perioperative Management of Patients with Pulmonary Comorbidities Undergoing Lung Resection].
    Kyobu geka. The Japanese journal of thoracic surgery, 2017, Volume: 70, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Comorbidity; Glucocorticoids; Humans; Lung Diseases, Interstitial; Lung Neoplasms; Methylprednisolone; Perioperative Care; Pneumonectomy; Postoperative Complications; Pulmonary Disease, Chronic Obstructive; Pyridones; Respiratory Insufficiency

2017
Japanese guideline for the treatment of idiopathic pulmonary fibrosis.
    Respiratory investigation, 2018, Volume: 56, Issue:4

    Topics: Acetylcysteine; Administration, Inhalation; Adrenal Cortex Hormones; Antineoplastic Combined Chemotherapy Protocols; Comorbidity; Disease Progression; Drug Therapy, Combination; Evidence-Based Medicine; Glycine; Humans; Idiopathic Pulmonary Fibrosis; Immunosuppressive Agents; Indoles; Japan; Lung Neoplasms; Meta-Analysis as Topic; Practice Guidelines as Topic; Prognosis; Pyridones; Quality of Health Care; Sulfonamides; Survival Rate

2018
Idiopathic Pulmonary Fibrosis and Lung Cancer: Mechanisms and Molecular Targets.
    International journal of molecular sciences, 2019, Jan-30, Volume: 20, Issue:3

    Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung Neoplasms; Myofibroblasts; Pyridones

2019

Trials

1 trial(s) available for pirfenidone and Cancer of Lung

ArticleYear
A phase II trial evaluating the efficacy and safety of perioperative pirfenidone for prevention of acute exacerbation of idiopathic pulmonary fibrosis in lung cancer patients undergoing pulmonary resection: West Japan Oncology Group 6711 L (PEOPLE Study).
    Respiratory research, 2016, 07-22, Volume: 17, Issue:1

    Topics: Administration, Oral; Disease Progression; Drug Administration Schedule; Humans; Idiopathic Pulmonary Fibrosis; Japan; Lung Neoplasms; Pneumonectomy; Pyridones; Risk Factors; Time Factors; Treatment Outcome

2016

Other Studies

23 other study(ies) available for pirfenidone and Cancer of Lung

ArticleYear
Uniportal video-assisted thoracic surgery and perioperative pirfenidone for lung cancer and idiopathic pulmonary fibrosis: a case report.
    The Journal of international medical research, 2021, Volume: 49, Issue:9

    Topics: Aged; Female; Humans; Idiopathic Pulmonary Fibrosis; Lung Neoplasms; Neoplasm Recurrence, Local; Pyridones; Thoracic Surgery, Video-Assisted

2021
Pirfenidone Sensitizes NCI-H460 Non-Small Cell Lung Cancer Cells to Paclitaxel and to a Combination of Paclitaxel with Carboplatin.
    International journal of molecular sciences, 2022, Mar-26, Volume: 23, Issue:7

    Topics: Antineoplastic Agents; Apoptosis; Carboplatin; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Humans; Lung Neoplasms; Paclitaxel; Pyridones

2022
Pirfenidone promotes the levels of exosomal miR-200 to down-regulate ZEB1 and represses the epithelial-mesenchymal transition of non-small cell lung cancer cells.
    Human cell, 2022, Volume: 35, Issue:6

    Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MicroRNAs; Neoplasm Invasiveness; Pyridones; Tumor Microenvironment; Zinc Finger E-box-Binding Homeobox 1

2022
Inhibition of CEMIP potentiates the effect of sorafenib on metastatic hepatocellular carcinoma by reducing the stiffness of lung metastases.
    Cell death & disease, 2023, 01-13, Volume: 14, Issue:1

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Humans; Hyaluronoglucosaminidase; Liver Neoplasms; Lung Neoplasms; Signal Transduction; Sorafenib; Tumor Microenvironment

2023
Pirfenidone inhibits motility of NSCLC cells by interfering with the urokinase system.
    Cellular signalling, 2020, Volume: 65

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Humans; Indoleacetic Acids; Lung Neoplasms; Membrane Proteins; Plasminogen Activator Inhibitor 1; Pyridones; Tumor Microenvironment; Urokinase-Type Plasminogen Activator

2020
Perioperative pirfenidone treatment for lung cancer patients with idiopathic pulmonary fibrosis.
    Surgery today, 2020, Volume: 50, Issue:5

    Topics: Disease Progression; Humans; Idiopathic Pulmonary Fibrosis; Lung Neoplasms; Perioperative Care; Postoperative Period; Pyridones; Retrospective Studies; Treatment Outcome

2020
Perioperative pirfenidone treatment as prophylaxis against acute exacerbation of idiopathic pulmonary fibrosis: a single-center analysis.
    Surgery today, 2020, Volume: 50, Issue:8

    Topics: Aged; Aged, 80 and over; Disease Progression; Female; Follow-Up Studies; Humans; Idiopathic Pulmonary Fibrosis; Lung Neoplasms; Male; Middle Aged; Negative Results; Patient Selection; Perioperative Care; Postoperative Complications; Prognosis; Pyridones; Survival Rate

2020
Effects of pirfenidone targeting the tumor microenvironment and tumor-stroma interaction as a novel treatment for non-small cell lung cancer.
    Scientific reports, 2020, 07-02, Volume: 10, Issue:1

    Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Differentiation; Cell Line, Tumor; Culture Media, Conditioned; Fibroblasts; Humans; Lung Neoplasms; Mice; Mice, Nude; Myofibroblasts; Pyridones; Stromal Cells; Tumor Microenvironment; Xenograft Model Antitumor Assays

2020
Safety and effectiveness of pirfenidone combined with carboplatin-based chemotherapy in patients with idiopathic pulmonary fibrosis and non-small cell lung cancer: A retrospective cohort study.
    Thoracic cancer, 2020, Volume: 11, Issue:11

    Topics: Aged; Carboplatin; Carcinoma, Non-Small-Cell Lung; Cohort Studies; Female; Humans; Idiopathic Pulmonary Fibrosis; Immune Checkpoint Inhibitors; Lung Neoplasms; Male; Middle Aged; Pyridones; Retrospective Studies

2020
Regression of Lung Squamous Cell Carcinoma after the Withdrawal of Cyclosporin A Combined with Pirfenidone Treatment in a Patient with Idiopathic Pulmonary Fibrosis.
    Internal medicine (Tokyo, Japan), 2021, Feb-15, Volume: 60, Issue:4

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Carcinoma, Squamous Cell; Cyclosporine; Humans; Idiopathic Pulmonary Fibrosis; Lung; Lung Neoplasms; Male; Pyridones; Treatment Outcome

2021
Pirfenidone facilitates immune infiltration and enhances the antitumor efficacy of PD-L1 blockade in mice.
    Oncoimmunology, 2020, 09-22, Volume: 9, Issue:1

    Topics: Animals; B7-H1 Antigen; Humans; Idiopathic Pulmonary Fibrosis; Lung Neoplasms; Mice; Pyridones

2020
Multifunctional ZnO@CuS nanoparticles cluster synergize chemotherapy and photothermal therapy for tumor metastasis.
    Nanomedicine : nanotechnology, biology, and medicine, 2021, Volume: 34

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Copper; Doxorubicin; Female; Humans; Lung Neoplasms; Metal Nanoparticles; Mice; Mice, Inbred BALB C; Photothermal Therapy; Pyridones; Sulfides; Xenograft Model Antitumor Assays; Zinc Oxide

2021
Treatment of steroid-resistant checkpoint inhibitor pneumonitis with pirfenidone: A case report.
    Thoracic cancer, 2021, Volume: 12, Issue:15

    Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Agents, Immunological; Carcinoma, Non-Small-Cell Lung; Drug-Related Side Effects and Adverse Reactions; Humans; Lung Neoplasms; Male; Pneumonia; Pyridones

2021
Reduced incidence of lung cancer in patients with idiopathic pulmonary fibrosis treated with pirfenidone.
    Respiratory investigation, 2018, Volume: 56, Issue:1

    Topics: Aged; Antineoplastic Agents; Emphysema; Female; Humans; Idiopathic Pulmonary Fibrosis; Incidence; Lung Neoplasms; Male; Middle Aged; Proportional Hazards Models; Pyridones; Retrospective Studies; Risk; Vital Capacity

2018
Does pirfenidone have anticancer effects in patients with idiopathic pulmonary fibrosis?
    Respiratory investigation, 2018, Volume: 56, Issue:2

    Topics: Antineoplastic Agents; Female; Humans; Idiopathic Pulmonary Fibrosis; Incidence; Lung Neoplasms; Male; Prognosis; Pyridones

2018
Pirfenidone decreases mesothelioma cell proliferation and migration via inhibition of ERK and AKT and regulates mesothelioma tumor microenvironment in vivo.
    Scientific reports, 2018, 07-03, Volume: 8, Issue:1

    Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Collagen; Extracellular Matrix; Female; Fibroblasts; Fibrosis; Humans; Lung Neoplasms; MAP Kinase Signaling System; Mesothelioma; Mesothelioma, Malignant; Mice; Mice, Inbred BALB C; Proto-Oncogene Proteins c-akt; Pyridones; Signal Transduction; Tumor Microenvironment; Xenograft Model Antitumor Assays

2018
[Successful resection of lung cancer with idiopathic pulmonary fibrosis treated by pirfenidone during perioperative period].
    Kyobu geka. The Japanese journal of thoracic surgery, 2013, Volume: 66, Issue:10

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Carcinoma, Squamous Cell; Combined Modality Therapy; Humans; Idiopathic Pulmonary Fibrosis; Lung Neoplasms; Male; Perioperative Period; Pyridones

2013
2014 American Thoracic Society International Conference.
    The Lancet. Respiratory medicine, 2014, Volume: 2, Issue:7

    Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humanized; Asthma; Congresses as Topic; Eosinophilia; Expectorants; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Idiopathic Pulmonary Fibrosis; Indoles; Lung Neoplasms; Protein Kinase Inhibitors; Pulmonary Disease, Chronic Obstructive; Pyridones; Respiratory Distress Syndrome

2014
Experience with perioperative pirfenidone for lung cancer surgery in patients with idiopathic pulmonary fibrosis.
    Surgery today, 2015, Volume: 45, Issue:10

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antifibrinolytic Agents; Disease Progression; Feasibility Studies; Female; Humans; Idiopathic Pulmonary Fibrosis; Lung Neoplasms; Male; Middle Aged; Perioperative Care; Postoperative Complications; Pyridones; Retrospective Studies; Treatment Outcome

2015
Efficacy of combined corticosteroid and pirfenidone for acute exacerbation of idiopathic pulmonary fibrosis after surgery for lung cancer: a case report.
    Respiratory investigation, 2015, Volume: 53, Issue:1

    Topics: Acute-Phase Reaction; Aged, 80 and over; Disease Progression; Drug Therapy, Combination; Glucocorticoids; Humans; Idiopathic Pulmonary Fibrosis; Infusions, Intravenous; Lung Neoplasms; Male; Methylprednisolone; Postoperative Complications; Prednisolone; Pulse Therapy, Drug; Pyridones; Treatment Outcome

2015
Effect of Perioperative Pirfenidone Treatment in Lung Cancer Patients With Idiopathic Pulmonary Fibrosis.
    The Annals of thoracic surgery, 2016, Volume: 102, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Disease Progression; Drug Administration Schedule; Drug Evaluation; Female; Humans; Idiopathic Pulmonary Fibrosis; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Perioperative Care; Pneumonectomy; Postoperative Complications; Pyridones; Retrospective Studies; Risk Assessment; Risk Factors; Smoking

2016
Targeting the cancer-associated fibroblasts as a treatment in triple-negative breast cancer.
    Oncotarget, 2016, Dec-13, Volume: 7, Issue:50

    Topics: Animals; Antineoplastic Agents; Cancer-Associated Fibroblasts; Cell Line, Tumor; Cell Proliferation; Collagen; Dose-Response Relationship, Drug; Female; Humans; Lung Neoplasms; Mice, Inbred BALB C; Molecular Targeted Therapy; Pyridones; Signal Transduction; Time Factors; Transforming Growth Factor beta; Triple Negative Breast Neoplasms; Tumor Burden; Tumor Cells, Cultured; Tumor Microenvironment; Xenograft Model Antitumor Assays

2016
Pirfenidone plays a biphasic role in inhibition of epithelial-mesenchymal transition in non-small cell lung cancer.
    Lung cancer (Amsterdam, Netherlands), 2017, Volume: 106

    Topics: Animals; Antineoplastic Agents; Carboplatin; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Epithelial-Mesenchymal Transition; Female; Fibroblasts; Humans; Lung Neoplasms; Mice; Phosphorylation; Pyridones; Signal Transduction; Smad2 Protein; Transforming Growth Factor beta1

2017