Compounds > pirfenidone
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pirfenidone and Acute Liver Injury, Drug-Induced

pirfenidone has been researched along with Acute Liver Injury, Drug-Induced in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Aoyagi, T; Goya, T; Imoto, K; Kato, M; Kohjima, M; Kurokawa, M; Kuwano, A; Ogawa, Y; Suzuki, H; Takahashi, M; Tanaka, M; Tashiro, S1
Han, J; Liu, X; Ma, X; Wang, X; Xu, J; Yuan, J; Zhao, L1
El-Agamy, DS1
Chen, XY; Wang, F; Wen, T; Wu, H1

Other Studies

5 other study(ies) available for pirfenidone and Acute Liver Injury, Drug-Induced

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Pirfenidone attenuates acetaminophen-induced liver injury via suppressing c-Jun N-terminal kinase phosphorylation.
    Toxicology and applied pharmacology, 2022, 01-01, Volume: 434

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Gene Expression Regulation, Enzymologic; JNK Mitogen-Activated Protein Kinases; Male; Mice; Phosphorylation; Pyridones

2022
Busulfan-induced hepatic sinusoidal endothelial cell injury: Modulatory role of pirfenidone for therapeutic purposes.
    Toxicology in vitro : an international journal published in association with BIBRA, 2023, Volume: 92

    Topics: Busulfan; Chemical and Drug Induced Liver Injury; Endothelial Cells; Hepatic Veno-Occlusive Disease; Humans; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta1

2023
Pirfenidone ameliorates concanavalin A-induced hepatitis in mice via modulation of reactive oxygen species/nuclear factor kappa B signalling pathways.
    The Journal of pharmacy and pharmacology, 2016, Volume: 68, Issue:12

    Topics: Animals; Antioxidants; Biomarkers; Chemical and Drug Induced Liver Injury; Concanavalin A; Cytoprotection; Disease Models, Animal; Hepatitis, Autoimmune; Liver; Male; Mice; NF-kappa B; Oxidative Stress; Pyridones; Reactive Oxygen Species; Signal Transduction

2016
Protective effects of pirfenidone on D-galactosamine and lipopolysaccharide-induced acute hepatotoxicity in rats.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2008, Volume: 57, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Galactosamine; Inflammation; Lipid Peroxidation; Lipopolysaccharides; Liver; Liver Diseases; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Pyridones; Rats; Rats, Sprague-Dawley; Severity of Illness Index

2008