piretanide has been researched along with Uremia in 2 studies
piretanide: potent inhibitor of chloride transport; structure
Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Pharmacokinetic data showed rapid and almost complete absorption (bioavailability 92%) and a rapid elimination with renal clearance of 50% of the total 200 ml/min in the normals and renal clearance of about 50% of actual GFR in the patients." | 1.27 | Pharmacokinetic-pharmacodynamic relationship of piretanide in healthy and uremic subjects. Determinants of the diuretic effect of a loop diuretic. ( Beermann, B; Odlind, B; Sjöström, P, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Elliott, HL | 1 |
| Ansari, AF | 1 |
| Campbell, BC | 1 |
| Lawrence, JR | 1 |
| Sjöström, P | 1 |
| Beermann, B | 1 |
| Odlind, B | 1 |
2 other studies available for piretanide and Uremia
| Article | Year |
|---|---|
Protein binding of piretanide in normal and uraemic serum.
Topics: Blood Proteins; Diuretics; Humans; Protein Binding; Serum Albumin; Sulfonamides; Ultrafiltration; Ur | 1982 |
Pharmacokinetic-pharmacodynamic relationship of piretanide in healthy and uremic subjects. Determinants of the diuretic effect of a loop diuretic.
Topics: Adult; Aged; Biological Availability; Diuresis; Dose-Response Relationship, Drug; Female; Humans; Ki | 1987 |