Page last updated: 2024-11-02

pirenzepine and Xerostomia

pirenzepine has been researched along with Xerostomia in 7 studies

Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.

Xerostomia: Decreased salivary flow.

Research Excerpts

ExcerptRelevanceReference
"Adding the atypical neuroleptic risperidone to a serotonin reuptake inhibitor (SRI) has benefited patients with treatment-refractory obsessive-compulsive disorder (OCD)."9.09Olanzapine augmentation for treatment-resistant obsessive-compulsive disorder. ( Elliott, MA; Koran, LM; Ringold, AL, 2000)
"The purpose of this study was to compare the efficacy of olanzapine with that of chlorpromazine plus benztropine in patients with treatment-resistant schizophrenia."9.08Olanzapine compared with chlorpromazine in treatment-resistant schizophrenia. ( Bartko, JJ; Conley, RR; Gounaris, C; Hegerty, J; Lingle, J; Love, R; Peszke, M; Richardson, C; Tamminga, CA; Zaremba, S, 1998)
"Adding the atypical neuroleptic risperidone to a serotonin reuptake inhibitor (SRI) has benefited patients with treatment-refractory obsessive-compulsive disorder (OCD)."5.09Olanzapine augmentation for treatment-resistant obsessive-compulsive disorder. ( Elliott, MA; Koran, LM; Ringold, AL, 2000)
"The purpose of this study was to compare the efficacy of olanzapine with that of chlorpromazine plus benztropine in patients with treatment-resistant schizophrenia."5.08Olanzapine compared with chlorpromazine in treatment-resistant schizophrenia. ( Bartko, JJ; Conley, RR; Gounaris, C; Hegerty, J; Lingle, J; Love, R; Peszke, M; Richardson, C; Tamminga, CA; Zaremba, S, 1998)
" The purpose of this study was to assess the potential for pharmacokinetic interaction between olanzapine and fluoxetine, a popular antidepressant that is a selective serotonin reuptake inhibitor."2.70Influence of fluoxetine on olanzapine pharmacokinetics. ( de Suray, JM; Gangji, D; Gossen, D; Onkelinx, C; Vandenhende, F, 2002)
"Pirenzepine is an antisecretory anticholinergic type drug that has recently been shown to be relatively free of usual anticholinergic side effects on esophageal smooth muscle."1.27Pirenzepine and propantheline effects on esophageal pressure responses to bethanechol. ( Castell, DO; Castell, JA; Dalton, CB; Hassan, M, 1986)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's1 (14.29)18.2507
2000's2 (28.57)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Passafaro, D1
Reina, S1
Sterin-Borda, L1
Borda, E1
Conley, RR1
Tamminga, CA1
Bartko, JJ1
Richardson, C1
Peszke, M1
Lingle, J1
Hegerty, J1
Love, R1
Gounaris, C1
Zaremba, S1
Koran, LM1
Ringold, AL1
Elliott, MA1
Gossen, D1
de Suray, JM1
Vandenhende, F1
Onkelinx, C1
Gangji, D1
Hassan, M1
Dalton, CB1
Castell, JA1
Castell, DO1
Rob, PM1
Narducci, F1
Bassotti, G1
Daniotti, S1
Del Soldato, P1
Pelli, MA1
Morelli, A1

Trials

4 trials available for pirenzepine and Xerostomia

ArticleYear
Olanzapine compared with chlorpromazine in treatment-resistant schizophrenia.
    The American journal of psychiatry, 1998, Volume: 155, Issue:7

    Topics: Adult; Akathisia, Drug-Induced; Analysis of Variance; Antipsychotic Agents; Basal Ganglia Diseases;

1998
Olanzapine augmentation for treatment-resistant obsessive-compulsive disorder.
    The Journal of clinical psychiatry, 2000, Volume: 61, Issue:7

    Topics: Adult; Benzodiazepines; Drug Administration Schedule; Drug Therapy, Combination; Fluoxetine; Humans;

2000
Influence of fluoxetine on olanzapine pharmacokinetics.
    AAPS pharmSci, 2002, Volume: 4, Issue:2

    Topics: Adult; Antipsychotic Agents; Asthenia; Benzodiazepines; Cross-Over Studies; Depressive Disorder; Dru

2002
Identification of muscarinic receptor subtype mediating colonic response to eating.
    Digestive diseases and sciences, 1985, Volume: 30, Issue:2

    Topics: Adult; Atropine; Benzodiazepinones; Colon; Eating; Electrophysiology; Female; Heart Rate; Humans; Ma

1985

Other Studies

3 other studies available for pirenzepine and Xerostomia

ArticleYear
Cholinergic autoantibodies from primary Sjögren's syndrome modulate submandibular gland Na+/K+-ATPase activity via prostaglandin E2 and cyclic AMP.
    European journal of oral sciences, 2010, Volume: 118, Issue:2

    Topics: Adult; Animals; Autoantibodies; Cells, Cultured; Cyclic AMP; Dinoprostone; Female; Humans; Immunoglo

2010
Pirenzepine and propantheline effects on esophageal pressure responses to bethanechol.
    The American journal of gastroenterology, 1986, Volume: 81, Issue:5

    Topics: Adult; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Esophagus; Female; Gastrointestinal Ag

1986
[Side effects of pirenzepine].
    Deutsche medizinische Wochenschrift (1946), 1988, Jan-08, Volume: 113, Issue:1

    Topics: Accommodation, Ocular; Female; Humans; Middle Aged; Pirenzepine; Urination Disorders; Xerostomia

1988