Page last updated: 2024-11-02

pirenzepine and Smoking Cessation

pirenzepine has been researched along with Smoking Cessation in 2 studies

Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.

Smoking Cessation: Discontinuing the habit of SMOKING.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wetterling, T1
Zullino, DF1
Delessert, D1
Eap, CB1
Preisig, M1
Baumann, P1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
An Open Label Trial of Ziprasidone as an Adjuvant for Clozapine- or Olanzapine-Associated Diabetes Mellitus or Impaired Fasting Glucose in Chronic Schizophrenia[NCT00351000]Phase 424 participants (Actual)Interventional2005-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change From Baseline in Fasting Glucose

Subjects on clozapine with adjunctive ziprasidone were compared to subjects on olanzapine with adjunctive ziprasidone on change in fasting glucose levels from baseline to study endpoint (week 6 - baseline) (NCT00351000)
Timeframe: baseline, week 6

Interventionmg/dL (Mean)
Clozapine Treatment With Adjunctive Ziprasidone5
Olanzapine Treatment With Adjunctive Ziprasidone-4.5

Change From Baseline on Fasting Insulin

Subjects on clozapine with adjunctive ziprasidone were compared to subjects on olanzapine with adjunctive ziprasidone on change in fasting insulin levels from baseline to study endpoint (week 6 - baseline) (NCT00351000)
Timeframe: baseline, week 6

InterventionmicroIU/L (Mean)
Clozapine Treatment With Adjunctive Ziprasidone1
Olanzapine Treatment With Adjunctive Ziprasidone-0.9

Reviews

1 review available for pirenzepine and Smoking Cessation

ArticleYear
Bodyweight gain with atypical antipsychotics. A comparative review.
    Drug safety, 2001, Volume: 24, Issue:1

    Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Humans; Mental Disorders; Olan

2001

Other Studies

1 other study available for pirenzepine and Smoking Cessation

ArticleYear
Tobacco and cannabis smoking cessation can lead to intoxication with clozapine or olanzapine.
    International clinical psychopharmacology, 2002, Volume: 17, Issue:3

    Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Clozapine; Confusion; Cytochro

2002