pirenzepine has been researched along with Sleep Wake Disorders in 7 studies
Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.
Sleep Wake Disorders: Abnormal sleep-wake schedule or pattern associated with the CIRCADIAN RHYTHM which affect the length, timing, and/or rigidity of the sleep-wake cycle relative to the day-night cycle.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This first clinical study of olanzapine in Japanese patients with schizophrenia was conducted to investigate the efficacy and safety of olanzapine." | 9.09 | Efficacy and safety of olanzapine, an atypical antipsychotic, in patients with schizophrenia: results of an open-label multicenter study in Japan. ( Ishigooka, J; Miura, S; Murasaki, M, 2001) |
| " A total of 115 patients with a DSM-IV diagnosis of bipolar disorder, manic or mixed, were randomized to olanzapine, 5 to 20 mg/d (n = 55), or placebo (n = 60)." | 5.09 | Efficacy of olanzapine in acute bipolar mania: a double-blind, placebo-controlled study. The Olanzipine HGGW Study Group. ( Banov, MC; Breier, A; Francis, J; Grundy, SL; Jacobs, TG; Janicak, PG; McElroy, SL; Risser, R; Sanger, T; Tohen, M; Tollefson, GD; Toma, V; Zhang, F, 2000) |
| "This first clinical study of olanzapine in Japanese patients with schizophrenia was conducted to investigate the efficacy and safety of olanzapine." | 5.09 | Efficacy and safety of olanzapine, an atypical antipsychotic, in patients with schizophrenia: results of an open-label multicenter study in Japan. ( Ishigooka, J; Miura, S; Murasaki, M, 2001) |
| " The newer atypical agents have a lower risk of EPS, but are associated in varying degrees with sedation, cardiovascular effects, anticholinergic effects, weight gain, sexual dysfunction, hepatic effects, lowered seizure threshold (primarily clozapine), and agranulocytosis (clozapine only)." | 4.80 | Adverse effects of the atypical antipsychotics. Collaborative Working Group on Clinical Trial Evaluations. ( , 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Paquet, V | 1 |
| Strul, J | 1 |
| Servais, L | 1 |
| Pelc, I | 1 |
| Fossion, P | 1 |
| Stein, MB | 1 |
| Kline, NA | 1 |
| Matloff, JL | 1 |
| Miller, TJ | 1 |
| Zipursky, RB | 1 |
| Perkins, D | 1 |
| Addington, J | 1 |
| Woods, SW | 1 |
| Hawkins, KA | 1 |
| Hoffman, R | 1 |
| Preda, A | 1 |
| Epstein, I | 1 |
| Addington, D | 1 |
| Lindborg, S | 1 |
| Marquez, E | 1 |
| Tohen, M | 2 |
| Breier, A | 2 |
| McGlashan, TH | 1 |
| Kraus, T | 1 |
| Schuld, A | 1 |
| Pollmächer, T | 1 |
| Jacobs, TG | 1 |
| Grundy, SL | 1 |
| McElroy, SL | 1 |
| Banov, MC | 1 |
| Janicak, PG | 1 |
| Sanger, T | 1 |
| Risser, R | 1 |
| Zhang, F | 1 |
| Toma, V | 1 |
| Francis, J | 1 |
| Tollefson, GD | 1 |
| Ishigooka, J | 1 |
| Murasaki, M | 1 |
| Miura, S | 1 |
1 review available for pirenzepine and Sleep Wake Disorders
| Article | Year |
|---|---|
Adverse effects of the atypical antipsychotics. Collaborative Working Group on Clinical Trial Evaluations.
Topics: Agranulocytosis; Antipsychotic Agents; Basal Ganglia Diseases; Benzodiazepines; Central Nervous Syst | 1998 |
4 trials available for pirenzepine and Sleep Wake Disorders
| Article | Year |
|---|---|
Adjunctive olanzapine for SSRI-resistant combat-related PTSD: a double-blind, placebo-controlled study.
Topics: Antipsychotic Agents; Benzodiazepines; Combat Disorders; Depressive Disorder; Double-Blind Method; D | 2002 |
The PRIME North America randomized double-blind clinical trial of olanzapine versus placebo in patients at risk of being prodromally symptomatic for psychosis. II. Baseline characteristics of the "prodromal" sample.
Topics: Adolescent; Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Comorbidity; Depressive | 2003 |
Efficacy of olanzapine in acute bipolar mania: a double-blind, placebo-controlled study. The Olanzipine HGGW Study Group.
Topics: Acute Disease; Adolescent; Adult; Aged; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Dou | 2000 |
Efficacy and safety of olanzapine, an atypical antipsychotic, in patients with schizophrenia: results of an open-label multicenter study in Japan.
Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Anxiety; Benzodiazepines; Female; Humans; Japa | 2001 |
2 other studies available for pirenzepine and Sleep Wake Disorders
| Article | Year |
|---|---|
Sleep-related eating disorder induced by olanzapine.
Topics: Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Drug Therapy, Combination; Feeding and Eati | 2002 |
Periodic leg movements in sleep and restless legs syndrome probably caused by olanzapine.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Humans; Leg; Male; Olanzapine; Pirenzepine; Restless L | 1999 |