pirenzepine has been researched along with Shock, Septic in 1 studies
Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.
Shock, Septic: Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pirenzepine pretreatment reduced while AF-DX116 enhanced expression of SOCS3 at mRNA level." | 1.51 | Muscarinic M1 and M2 receptor subtypes play opposite roles in LPS-induced septic shock. ( Geng, B; Li, M; Liu, L; Wang, Z, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Z | 1 |
| Li, M | 1 |
| Liu, L | 1 |
| Geng, B | 1 |
1 other study available for pirenzepine and Shock, Septic
| Article | Year |
|---|---|
Muscarinic M1 and M2 receptor subtypes play opposite roles in LPS-induced septic shock.
Topics: Animals; Atropine; Cytokines; Lipopolysaccharides; Liver; Lung; Macrophages; Male; Mice; Mice, Inbre | 2019 |