pirenzepine has been researched along with Recrudescence in 68 studies
Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to estimate the long-term effectiveness of olanzapine as adjunctive therapy in patients with bipolar disorder who exhibited an inadequate response to mood stabilizers." | 9.09 | Olanzapine as long-term adjunctive therapy in treatment-resistant bipolar disorder. ( Benabarre, A; Colom, F; Corbella, B; Gastó, C; Gilaberte, I; Martínez-Arán, A; Reinares, M; Tohen, M; Vieta, E, 2001) |
| "Two studies compared the efficacy of standard-dose oral olanzapine (5 to 15 mg a day) with placebo and with ineffective-dose olanzapine (1 mg a day) in maintenance therapy of schizophrenia." | 9.08 | Standard olanzapine versus placebo and ineffective-dose olanzapine in the maintenance treatment of schizophrenia. ( Beasley, CM; Dellva, MA; Tollefson, GD; Tran, P; Wentley, AL, 1997) |
| "The effect of cimetidine and pirenzepine on the maintenance of healing in duodenal ulceration has been compared in a multi-centre, controlled study." | 9.06 | Comparison of cimetidine and pirenzepine in the healing and maintenance of remission in duodenal ulcer. ( Gent, AE; Hellier, MD, 1990) |
| "A double-blind, controlled study with either 50 mg of pirenzepine or a placebo once a day was performed in 128 patients to determine the effect of pirenzepine against relapses of duodenal ulcer, the healing of the subjects' former ulcers having been confirmed endoscopically." | 9.06 | A study on the prevention of duodenal ulcer recurrence with pirenzepine. ( Fukumoto, S; Kawai, K; Kohli, Y, 1987) |
| "Eighty-four patients with healed duodenal ulcers were treated for 1 year with pirenzepine, 50 mg twice daily, or placebo in this double-blind, randomized, multicenter trial." | 9.06 | Prevention of duodenal ulcer recurrence by pirenzepine 50 mg twice daily. ( Brassine, A; Pelckmans, P; Pen, J; Rutgeerts, P; Van der Veken, J; Van Maercke, Y; Vantrappen, G, 1987) |
| "The efficacy of pirenzepin--of anticholinergic effect--and the H2-receptor blocking cimetidine has been studied in duodenal ulcer with random, double blind fashion." | 9.06 | [Pirenzepine and cimetidine in the treatment of duodenal ulcer]. ( Papp, J; Schandl, L; Szathmári, M; Tulassay, Z, 1988) |
| "The effectiveness of pirenzepine in the prevention of duodenal ulcer relapses was assessed by means of a double-blind controlled trial versus cimetidine." | 9.05 | Long-term management of duodenal ulcer with pirenzepine and cimetidine: a double-blind controlled clinical trial. ( Cacioli, D; Galeone, M; Giorgi-Conciato, M; Moise, G; Stock, F; Toti, GL, 1983) |
| "Recurrence rates of chronic duodenal ulcer after initial therapy with pirenzepine or cimetidine were investigated in a prospective, randomized trial with a total of 80 patients." | 9.05 | [Recurrence of chronic duodenal ulcer following initial therapy with pirenzepine or cimetidine]. ( Dufek, W; Hentschel, E; Schütze, K, 1985) |
| "The effect of pirenzepine and cimetidine on healing, symptoms and relapse rate of duodenal ulcer was studied in a placebo-controlled double-blind trial." | 9.05 | Treatment and relapse prophylaxis of duodenal ulcer with pirenzepine and cimetidine. ( Birchler, R; Blum, AL; Eichenberger, PM; Giger, M; Gonvers, JJ; Mattle, W; Müller-Lissner, SA; Pelloni, S, 1982) |
| "Sixty out-patients with duodenal ulcers that were healed at the end of a 4-week treatment with pirenzepine, cimetidine or placebo were admitted to a double-blind placebo-controlled trial to study the effectiveness of pirenzepine (100 mg/daily) in preventing recurrence of ulcers." | 9.05 | Long-term treatment of duodenal ulcer with pirenzepine. A double-blind, placebo-controlled trial. ( Bianchi Porro, G; D'Imperio, N; Dal Monte, PR; Daniotti, S; Giuliani-Piccari, G; Petrillo, M, 1982) |
| "Twenty-eight patients with healed duodenal ulcer completed a 12-month double-blind trial to compare the effects of pirenzepine (25 mg twice daily) and placebo on the prevention of duodenal ulcer relapse." | 9.05 | Maintenance treatment of recurrent duodenal ulceration with pirenzepine. ( Bianchi Porro, G; Petrillo, M, 1980) |
| "The effect of pirenzepine and cimetidine on healing, symptoms, and relapse rate of duodenal ulcer was studied in a placebo controlled double blind trial." | 9.05 | [Treatment and prevention of recurrence of duodenal ulcer with pirenzepin and cimetidine]. ( Birchler, R; Blum, AL; Eichenberger, PM; Giger, M; Gonvers, JJ; Mattle, W; Müller-Lissner, SA; Pelloni, S, 1982) |
| "The frequency of neuroleptic malignant syndrome (NMS) after clozapine or olanzapine is low and often of non-serious nature." | 8.82 | [Life threatening neuroleptic malignant syndrome due to olanzapine]. ( Becker, T; Kopf, A; Köster, J; Krömker, H; Schulz, A, 2003) |
| "Three studies compared olanzapine and haloperidol given orally in maintenance therapy for schizophrenia and related psychoses." | 7.70 | Oral olanzapine versus oral haloperidol in the maintenance treatment of schizophrenia and related psychoses. ( Beasley, CM; Dellva, MA; Tollefson, GD; Tran, PV; Wentley, AL, 1998) |
| "We retrospectively investigated the efficacy of high dose omeprazole compared to a combined therapy of famotidine, pirenzepine and antacid for acute upper gastrointestinal hemorrhage (AUGIH) also adjuvant to endoscopic injection therapy if indicated." | 7.69 | [High-dose omeprazole versus famotidine, pirenzepine and antacid in therapy of acute upper gastrointestinal hemorrhage in a retrospective comparison]. ( Busam, J; Garbe, WE, 1994) |
| "Twenty-three endoscopically healed duodenal ulcer patients entered a long-term treatment with pirenzepine for 1 year (two 25-mg tablets at breakfast and two tablets at bedtime)." | 7.66 | Long-term treatment of duodenal ulcer with pirenzepine; gastric pH values and incidence of relapses: an open pilot study. ( Accadia, L; Federici, T; Gabbrielli, A; Gabbrielli, L; Giorgi-Conciato, M, 1983) |
| "A total of 60 patients with endoscopically diagnosed duodenal ulcer were treated with pirenzepine or cimetidine for 8-10 weeks until endoscopic healing of the ulcer." | 7.66 | Pirenzepine in long-term therapy for duodenal ulcer. ( Bresci, G; Capria, A; Del Tacca, M; Geloni, M; Polloni, A; Rindi, G, 1983) |
| "Risperidone-treated subjects with a greater degree of acute mood change were both 3." | 6.69 | The course of depressive symptoms in predicting relapse in schizophrenia: a double-blind, randomized comparison of olanzapine and risperidone. ( Andersen, SW; Tollefson, GD; Tran, PV, 1999) |
| "Pirenzepine is an antimuscarinic drug highly selective for M1 receptors, which proved to be effective in the treatment of peptic ulcer." | 6.66 | [Pharmacologic treatment of duodenal ulcer. Short and long-term results with pirenzepine in ambulatory patients]. ( Barberani, F; Carpinelli, D; D'Ambrosio, C; Della Spoletina, A; Fiorini, MA; Nicolao, V; Schiaroli, G; Valentini, P, 1986) |
| "Seasonal accumulation of duodenal ulcer recurrences suggests that maintenance therapy could be limited to the more risky periods." | 6.66 | Seasonal prevention of duodenal ulcer recurrences with pirenzepine. ( Butruk, E; Gabryelewicz, A; Gibiński, K; Habior, A; Hasik, J; Klinoewicz, H; Kosidło, S; Marlioz, K; Nowak, A; Starzyńska, T, 1987) |
| " Because it has been suggested that the lower relapse rate for duodenal ulcer following colloidal bismuth subcitrate (CBS) is due to suppression of C pylori we investigated different formulations and dosing of CBS for their efficacy in clearing C pylori." | 6.66 | Treatment of Campylobacter pylori gastritis: a pilot study using pirenzepine dihydrochloride (Gastrozepin) and three formulations of colloidal bismuth subcitrate (De-Nol). ( Ali, MR; Brown, P; Lane, M; Morris, A; Palmer, R, 1988) |
| " To provide the therapeutic benefits of maintenance medication without its drawbacks, intermittent dosing and long-term therapy with reduced doses of conventional medications have been explored." | 6.40 | Olanzapine in the long-term treatment of schizophrenia. ( Kane, J, 1999) |
| "Pirenzepine is a 'selective' antimuscarinic agent which, unlike classic anticholinergic agents, inhibits gastric acid secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular and urinary functions." | 6.37 | Pirenzepine. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in peptic ulcer disease and other allied diseases. ( Brogden, RN; Carmine, AA, 1985) |
| "Pirenzepine appears to be an effective drug for the short-term treatment of duodenal ulcer." | 6.36 | Pirenzepine in the treatment of peptic ulcer disease. Review and commentary. ( Bianchi Porro, G; Petrillo, M, 1982) |
| "To more clearly clarify the efficacy of the atypical antipsychotics compared to conventional antipsychotics, we add data on the outcome of patients diagnosed with schizophrenia from two large, international clinical trials comparing olanzapine with haloperidol (n = 1996) and olanzapine with risperidone (n = 339)." | 5.10 | Time to study discontinuation, relapse, and compliance with atypical or conventional antipsychotics in schizophrenia and related disorders. ( Berg, PH; Glick, ID, 2002) |
| "The aim of this study was to estimate the long-term effectiveness of olanzapine as adjunctive therapy in patients with bipolar disorder who exhibited an inadequate response to mood stabilizers." | 5.09 | Olanzapine as long-term adjunctive therapy in treatment-resistant bipolar disorder. ( Benabarre, A; Colom, F; Corbella, B; Gastó, C; Gilaberte, I; Martínez-Arán, A; Reinares, M; Tohen, M; Vieta, E, 2001) |
| "Two studies compared the efficacy of standard-dose oral olanzapine (5 to 15 mg a day) with placebo and with ineffective-dose olanzapine (1 mg a day) in maintenance therapy of schizophrenia." | 5.08 | Standard olanzapine versus placebo and ineffective-dose olanzapine in the maintenance treatment of schizophrenia. ( Beasley, CM; Dellva, MA; Tollefson, GD; Tran, P; Wentley, AL, 1997) |
| "Four hundred and two patients with peptic ulcer were selected for acute therapy with either pirenzepine (100 mg/day) or cimetidine (800 mg/day) using the envelope method." | 5.07 | Predictors of relapse in peptic ulcer. ( Asaki, S; Inoue, S; Ishimori, A; Kano, A; Kawakami, K; Kawamura, T; Koizumi, F; Takahashi, T, 1992) |
| "We randomized 785 patients with healed duodenal ulcer to receive: (1) no treatment; (2) mealtime antacids with an acid-neutralizing capacity of 80 mmol/day; (3) an antidepressant, trimipramine 25 mg; (4) an anticholinergic, pirenzepine 50 mg; (5) cimetidine 200 mg; (6) cimetidine 400 mg; (7) ranitidine 150 mg; or (8) sucralfate 1 g twice a day." | 5.07 | Maintenance therapy for duodenal ulcer: a randomized controlled comparison of seven forms of treatment. ( Hui, WM; Lai, CL; Lam, SK; Lok, AS; Ng, MM, 1992) |
| "A double-blind, controlled study with either 50 mg of pirenzepine or a placebo once a day was performed in 128 patients to determine the effect of pirenzepine against relapses of duodenal ulcer, the healing of the subjects' former ulcers having been confirmed endoscopically." | 5.06 | A study on the prevention of duodenal ulcer recurrence with pirenzepine. ( Fukumoto, S; Kawai, K; Kohli, Y, 1987) |
| "Eighty-four patients with healed duodenal ulcers were treated for 1 year with pirenzepine, 50 mg twice daily, or placebo in this double-blind, randomized, multicenter trial." | 5.06 | Prevention of duodenal ulcer recurrence by pirenzepine 50 mg twice daily. ( Brassine, A; Pelckmans, P; Pen, J; Rutgeerts, P; Van der Veken, J; Van Maercke, Y; Vantrappen, G, 1987) |
| "The efficacy of pirenzepin--of anticholinergic effect--and the H2-receptor blocking cimetidine has been studied in duodenal ulcer with random, double blind fashion." | 5.06 | [Pirenzepine and cimetidine in the treatment of duodenal ulcer]. ( Papp, J; Schandl, L; Szathmári, M; Tulassay, Z, 1988) |
| "The effect of cimetidine and pirenzepine on the maintenance of healing in duodenal ulceration has been compared in a multi-centre, controlled study." | 5.06 | Comparison of cimetidine and pirenzepine in the healing and maintenance of remission in duodenal ulcer. ( Gent, AE; Hellier, MD, 1990) |
| "The effect of pirenzepine and cimetidine on healing, symptoms and relapse rate of duodenal ulcer was studied in a placebo-controlled double-blind trial." | 5.05 | Treatment and relapse prophylaxis of duodenal ulcer with pirenzepine and cimetidine. ( Birchler, R; Blum, AL; Eichenberger, PM; Giger, M; Gonvers, JJ; Mattle, W; Müller-Lissner, SA; Pelloni, S, 1982) |
| "Recurrence rates of chronic duodenal ulcer after initial therapy with pirenzepine or cimetidine were investigated in a prospective, randomized trial with a total of 80 patients." | 5.05 | [Recurrence of chronic duodenal ulcer following initial therapy with pirenzepine or cimetidine]. ( Dufek, W; Hentschel, E; Schütze, K, 1985) |
| "The effectiveness of pirenzepine in the prevention of duodenal ulcer relapses was assessed by means of a double-blind controlled trial versus cimetidine." | 5.05 | Long-term management of duodenal ulcer with pirenzepine and cimetidine: a double-blind controlled clinical trial. ( Cacioli, D; Galeone, M; Giorgi-Conciato, M; Moise, G; Stock, F; Toti, GL, 1983) |
| "Sixty out-patients with duodenal ulcers that were healed at the end of a 4-week treatment with pirenzepine, cimetidine or placebo were admitted to a double-blind placebo-controlled trial to study the effectiveness of pirenzepine (100 mg/daily) in preventing recurrence of ulcers." | 5.05 | Long-term treatment of duodenal ulcer with pirenzepine. A double-blind, placebo-controlled trial. ( Bianchi Porro, G; D'Imperio, N; Dal Monte, PR; Daniotti, S; Giuliani-Piccari, G; Petrillo, M, 1982) |
| "Twenty-eight patients with healed duodenal ulcer completed a 12-month double-blind trial to compare the effects of pirenzepine (25 mg twice daily) and placebo on the prevention of duodenal ulcer relapse." | 5.05 | Maintenance treatment of recurrent duodenal ulceration with pirenzepine. ( Bianchi Porro, G; Petrillo, M, 1980) |
| "The effect of pirenzepine and cimetidine on healing, symptoms, and relapse rate of duodenal ulcer was studied in a placebo controlled double blind trial." | 5.05 | [Treatment and prevention of recurrence of duodenal ulcer with pirenzepin and cimetidine]. ( Birchler, R; Blum, AL; Eichenberger, PM; Giger, M; Gonvers, JJ; Mattle, W; Müller-Lissner, SA; Pelloni, S, 1982) |
| "The frequency of neuroleptic malignant syndrome (NMS) after clozapine or olanzapine is low and often of non-serious nature." | 4.82 | [Life threatening neuroleptic malignant syndrome due to olanzapine]. ( Becker, T; Kopf, A; Köster, J; Krömker, H; Schulz, A, 2003) |
| "The unprecedented level of activity in the development of new antipsychotic medications can be traced to the 1989 approval of clozapine by the US Food and Drug Administration for treatment of refractory schizophrenia." | 4.79 | New antipsychotic medications: strategies for evaluation and selected findings. ( Schooler, NR, 1997) |
| "The healing rate of duodenal ulcers may be accelerated by secretory inhibitors such as histamine H2-receptor antagonists and pirenzepine, by antacids, by protective drugs such as sucralfate and colloidal bismuth, and by antidepressant drugs such as trimipramine." | 4.77 | Therapeutic approach to ulcer healing. ( Blum, AL, 1985) |
| "Three studies compared olanzapine and haloperidol given orally in maintenance therapy for schizophrenia and related psychoses." | 3.70 | Oral olanzapine versus oral haloperidol in the maintenance treatment of schizophrenia and related psychoses. ( Beasley, CM; Dellva, MA; Tollefson, GD; Tran, PV; Wentley, AL, 1998) |
| "We retrospectively investigated the efficacy of high dose omeprazole compared to a combined therapy of famotidine, pirenzepine and antacid for acute upper gastrointestinal hemorrhage (AUGIH) also adjuvant to endoscopic injection therapy if indicated." | 3.69 | [High-dose omeprazole versus famotidine, pirenzepine and antacid in therapy of acute upper gastrointestinal hemorrhage in a retrospective comparison]. ( Busam, J; Garbe, WE, 1994) |
| "A total of 60 patients with endoscopically diagnosed duodenal ulcer were treated with pirenzepine or cimetidine for 8-10 weeks until endoscopic healing of the ulcer." | 3.66 | Pirenzepine in long-term therapy for duodenal ulcer. ( Bresci, G; Capria, A; Del Tacca, M; Geloni, M; Polloni, A; Rindi, G, 1983) |
| "Twenty-three endoscopically healed duodenal ulcer patients entered a long-term treatment with pirenzepine for 1 year (two 25-mg tablets at breakfast and two tablets at bedtime)." | 3.66 | Long-term treatment of duodenal ulcer with pirenzepine; gastric pH values and incidence of relapses: an open pilot study. ( Accadia, L; Federici, T; Gabbrielli, A; Gabbrielli, L; Giorgi-Conciato, M, 1983) |
| " The patients were treated with conventional antipsychotics for seven days after admission and were then randomised to the treatment arms with risperidone (4 mg/day) or with olanzapine (10 mg/day) at a fixed dosage in the first week and thereafter in flexible dosages for the remaining seven weeks." | 2.71 | Measurement of simple reaction time in antipsychotic treatment of patients with schizophrenia. ( Kores Plesnicar, B; Krajnc, I; Tomori, M; Zalar, B, 2003) |
| "Risperidone-treated subjects with a greater degree of acute mood change were both 3." | 2.69 | The course of depressive symptoms in predicting relapse in schizophrenia: a double-blind, randomized comparison of olanzapine and risperidone. ( Andersen, SW; Tollefson, GD; Tran, PV, 1999) |
| " Because it has been suggested that the lower relapse rate for duodenal ulcer following colloidal bismuth subcitrate (CBS) is due to suppression of C pylori we investigated different formulations and dosing of CBS for their efficacy in clearing C pylori." | 2.66 | Treatment of Campylobacter pylori gastritis: a pilot study using pirenzepine dihydrochloride (Gastrozepin) and three formulations of colloidal bismuth subcitrate (De-Nol). ( Ali, MR; Brown, P; Lane, M; Morris, A; Palmer, R, 1988) |
| "Pirenzepine is an antimuscarinic drug highly selective for M1 receptors, which proved to be effective in the treatment of peptic ulcer." | 2.66 | [Pharmacologic treatment of duodenal ulcer. Short and long-term results with pirenzepine in ambulatory patients]. ( Barberani, F; Carpinelli, D; D'Ambrosio, C; Della Spoletina, A; Fiorini, MA; Nicolao, V; Schiaroli, G; Valentini, P, 1986) |
| "Seasonal accumulation of duodenal ulcer recurrences suggests that maintenance therapy could be limited to the more risky periods." | 2.66 | Seasonal prevention of duodenal ulcer recurrences with pirenzepine. ( Butruk, E; Gabryelewicz, A; Gibiński, K; Habior, A; Hasik, J; Klinoewicz, H; Kosidło, S; Marlioz, K; Nowak, A; Starzyńska, T, 1987) |
| "Akathisia (restlessness and characteristic movements of the legs) is one of the most disagreeable extrapyramidal side effects and often causes non-compliance." | 2.41 | [Drug-induced akathisia]. ( van Harten, PN, 2002) |
| "The pharmacologic treatment of schizophrenia remains a critical component in the short- and long-term management of this disease." | 2.40 | Pharmacologic treatment of schizophrenia. ( Kane, JM, 1999) |
| " To provide the therapeutic benefits of maintenance medication without its drawbacks, intermittent dosing and long-term therapy with reduced doses of conventional medications have been explored." | 2.40 | Olanzapine in the long-term treatment of schizophrenia. ( Kane, J, 1999) |
| " They suggest that as atypical antipsychotics like olanzapine are more widely used, some problems associated with the long-term use of conventional antipsychotics will diminish, but other issues and concerns will be more common." | 2.39 | Atypical antipsychotic drugs and long-term outcome in schizophrenia. ( Aquila, R; Standard, J; Weiden, P, 1996) |
| "Pirenzepine is a 'selective' antimuscarinic agent which, unlike classic anticholinergic agents, inhibits gastric acid secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular and urinary functions." | 2.37 | Pirenzepine. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in peptic ulcer disease and other allied diseases. ( Brogden, RN; Carmine, AA, 1985) |
| "Pirenzepine appears to be an effective drug for the short-term treatment of duodenal ulcer." | 2.36 | Pirenzepine in the treatment of peptic ulcer disease. Review and commentary. ( Bianchi Porro, G; Petrillo, M, 1982) |
| "Duodenal ulcer was found to relapse more frequently in patients with total serum pepsinogen more than 109 micrograms tyr X ml-1 X 24 h-1 and in patients with maximal acid output more than 60 mmol/h (Logrank test; both p less than 0." | 1.27 | Recurrence of duodenal ulcer under continuous antisecretory treatment: an approach to the detection of predictive markers. ( Battaglia, G; Burlina, A; Di Mario, F; Farini, R; Naccarato, R; Piccoli, A; Plebani, M; Vianello, F, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (48.53) | 18.7374 |
| 1990's | 24 (35.29) | 18.2507 |
| 2000's | 11 (16.18) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Crocq, MA | 1 |
| Leclercq, P | 1 |
| Guillon, MS | 1 |
| Bailey, PE | 1 |
| Kores Plesnicar, B | 1 |
| Zalar, B | 1 |
| Tomori, M | 1 |
| Krajnc, I | 1 |
| Kopf, A | 1 |
| Köster, J | 1 |
| Schulz, A | 1 |
| Krömker, H | 1 |
| Becker, T | 1 |
| Battaglia, G | 3 |
| Farini, R | 2 |
| Di Mario, F | 3 |
| Piccoli, A | 2 |
| Plebani, M | 2 |
| Vianello, F | 2 |
| Burlina, A | 1 |
| Naccarato, R | 2 |
| Clémençon, GH | 1 |
| Holtermüller, KH | 1 |
| Morelli, A | 1 |
| Narducci, F | 1 |
| Pelli, MA | 1 |
| Farroni, F | 1 |
| Daniotti, S | 2 |
| Del Soldato, P | 1 |
| Piper, DW | 1 |
| Tytgat, GN | 1 |
| Hameeteman, W | 1 |
| van Olffen, GH | 1 |
| Federici, T | 1 |
| Accadia, L | 1 |
| Gabbrielli, L | 1 |
| Giorgi-Conciato, M | 2 |
| Gabbrielli, A | 1 |
| Galeone, M | 1 |
| Cacioli, D | 1 |
| Toti, GL | 1 |
| Moise, G | 1 |
| Stock, F | 1 |
| Grigor'ev, PIa | 2 |
| Khar'kovskiĭ, NN | 1 |
| Elina, NA | 1 |
| El'tsova, NB | 1 |
| Elisova, NV | 1 |
| Capria, A | 2 |
| Bresci, G | 2 |
| Polloni, A | 1 |
| Rindi, G | 2 |
| Geloni, M | 2 |
| Del Tacca, M | 1 |
| Krempler, F | 1 |
| Sandhofer, F | 1 |
| Kalk, A | 1 |
| Eichenberger, PM | 2 |
| Giger, M | 2 |
| Mattle, W | 2 |
| Pelloni, S | 2 |
| Müller-Lissner, SA | 2 |
| Gonvers, JJ | 2 |
| Birchler, R | 2 |
| Blum, AL | 3 |
| Bianchi Porro, G | 3 |
| Petrillo, M | 3 |
| Dal Monte, PR | 1 |
| Giuliani-Piccari, G | 1 |
| D'Imperio, N | 1 |
| Berndt, H | 1 |
| Otto, R | 1 |
| Iakovenko, AV | 1 |
| Vasil'ev, IV | 1 |
| Ishimori, A | 5 |
| Busam, J | 1 |
| Garbe, WE | 1 |
| Niv, Y | 1 |
| Chamud, M | 1 |
| Mysh, V | 1 |
| Weiden, P | 1 |
| Aquila, R | 1 |
| Standard, J | 1 |
| Dellva, MA | 2 |
| Tran, P | 1 |
| Tollefson, GD | 3 |
| Wentley, AL | 2 |
| Beasley, CM | 2 |
| Schooler, NR | 1 |
| Weisler, RH | 1 |
| Ahearn, EP | 1 |
| Davidson, JR | 1 |
| Wallace, CD | 1 |
| Tran, PV | 2 |
| Fertig, MK | 1 |
| Brooks, VG | 1 |
| Shelton, PS | 1 |
| English, CW | 1 |
| Hanel, RA | 1 |
| Sandmann, MC | 1 |
| Kranich, M | 1 |
| De Bittencourt, PR | 1 |
| Kane, J | 1 |
| Andersen, SW | 1 |
| Vercueil, L | 1 |
| Foucher, J | 1 |
| Kostakoğlu, AE | 1 |
| Rezaki, M | 1 |
| Göğüş, A | 1 |
| Gheorghiu, S | 1 |
| Knobler, HY | 1 |
| Drumer, D | 1 |
| Kane, JM | 1 |
| Lal, S | 1 |
| Iskandar, H | 1 |
| Llorca, PM | 1 |
| Vaiva, G | 1 |
| Lancon, C | 1 |
| Vieta, E | 1 |
| Reinares, M | 1 |
| Corbella, B | 1 |
| Benabarre, A | 1 |
| Gilaberte, I | 1 |
| Colom, F | 1 |
| Martínez-Arán, A | 1 |
| Gastó, C | 1 |
| Tohen, M | 1 |
| Songer, DA | 1 |
| Barclay, JC | 1 |
| van Harten, PN | 1 |
| Glick, ID | 1 |
| Berg, PH | 1 |
| Parker, G | 1 |
| Kawamura, T | 3 |
| Koizumi, F | 3 |
| Kawakami, K | 1 |
| Inoue, S | 1 |
| Kano, A | 1 |
| Takahashi, T | 1 |
| Asaki, S | 1 |
| Minushkin, ON | 1 |
| Zverkov, IV | 1 |
| Hui, WM | 1 |
| Lam, SK | 1 |
| Lok, AS | 1 |
| Ng, MM | 1 |
| Lai, CL | 1 |
| Fujimoto, H | 1 |
| Gent, AE | 1 |
| Hellier, MD | 1 |
| Lane, MR | 1 |
| Lee, SP | 2 |
| Ishikawa, M | 1 |
| Saito, H | 1 |
| Sato, J | 1 |
| Szathmári, M | 1 |
| Tulassay, Z | 1 |
| Schandl, L | 1 |
| Papp, J | 1 |
| Morris, A | 1 |
| Brown, P | 1 |
| Ali, MR | 1 |
| Lane, M | 1 |
| Palmer, R | 1 |
| Rutgeerts, P | 1 |
| Vantrappen, G | 1 |
| Brassine, A | 1 |
| Van Maercke, Y | 1 |
| Pen, J | 1 |
| Pelckmans, P | 1 |
| Van der Veken, J | 1 |
| Kohli, Y | 1 |
| Fukumoto, S | 1 |
| Kawai, K | 1 |
| Yachi, A | 1 |
| Yabana, T | 1 |
| Takai, Y | 1 |
| Magni, G | 1 |
| Borgherini, G | 1 |
| Donzella, G | 1 |
| Pellegrini, C | 1 |
| Federici, G | 1 |
| Corsini, G | 1 |
| Gibiński, K | 1 |
| Nowak, A | 1 |
| Butruk, E | 1 |
| Habior, A | 1 |
| Gabryelewicz, A | 1 |
| Kosidło, S | 1 |
| Hasik, J | 1 |
| Klinoewicz, H | 1 |
| Marlioz, K | 1 |
| Starzyńska, T | 1 |
| Barberani, F | 1 |
| Della Spoletina, A | 1 |
| D'Ambrosio, C | 1 |
| Schiaroli, G | 1 |
| Fiorini, MA | 1 |
| Nicolao, V | 1 |
| Carpinelli, D | 1 |
| Valentini, P | 1 |
| Hentschel, E | 1 |
| Schütze, K | 1 |
| Dufek, W | 1 |
| Carmine, AA | 1 |
| Brogden, RN | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effectiveness of Paliperidone ER(Invega®) on Depressive Symptoms of Schizophrenia Patients: A 8-week Open-label Prospective, Non-comparative Study[NCT01399450] | Phase 4 | 11 participants (Actual) | Interventional | 2011-08-31 | Completed | ||
| A Double-blind, Randomized, Placebo-controlled Trial of Berberine as an Adjuvant to Treat Antipsychotic-induced Metabolic Syndrome in Patients With Schizophrenia Spectrum Disorders[NCT02983188] | Phase 2/Phase 3 | 113 participants (Actual) | Interventional | 2018-04-25 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
12 reviews available for pirenzepine and Recrudescence
| Article | Year |
|---|---|
[Life threatening neuroleptic malignant syndrome due to olanzapine].
Topics: Antipsychotic Agents; Benzodiazepines; Critical Care; Electroconvulsive Therapy; Female; Haloperidol | 2003 |
[Conservative therapy of peptic ulcer].
Topics: Antacids; Benzodiazepinones; Carbenoxolone; Cimetidine; Gastric Acid; Gastroscopy; Histamine H2 Anta | 1980 |
Drugs for the prevention of peptic ulcer recurrence.
Topics: Aluminum; Anti-Ulcer Agents; Benzodiazepinones; Cimetidine; Humans; Parasympatholytics; Peptic Ulcer | 1983 |
Sucralfate, bismuth compounds, substituted benzimidazoles, trimipramine and pirenzepine in the short- and long-term treatment of duodenal ulcer.
Topics: Aluminum; Animals; Antacids; Anti-Ulcer Agents; Benzimidazoles; Benzodiazepinones; Bismuth; Clinical | 1984 |
Pirenzepine in the treatment of peptic ulcer disease. Review and commentary.
Topics: Anti-Ulcer Agents; Benzodiazepinones; Humans; Parasympatholytics; Peptic Ulcer; Pirenzepine; Recurre | 1982 |
Atypical antipsychotic drugs and long-term outcome in schizophrenia.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Clinical Trials as Topic; Clozapine; Follow-Up Studies | 1996 |
New antipsychotic medications: strategies for evaluation and selected findings.
Topics: Antipsychotic Agents; Benzodiazepines; Chronic Disease; Clinical Trials as Topic; Clozapine; Drug Ad | 1997 |
Olanzapine in the long-term treatment of schizophrenia.
Topics: Antipsychotic Agents; Benzodiazepines; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; H | 1999 |
Pharmacologic treatment of schizophrenia.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Humans; Olanzapine; Pirenzepin | 1999 |
[Drug-induced akathisia].
Topics: Akathisia, Drug-Induced; Antipsychotic Agents; Benzodiazepines; Clozapine; Diabetes Complications; D | 2002 |
Therapeutic approach to ulcer healing.
Topics: Aluminum; Antacids; Anti-Ulcer Agents; Antidepressive Agents; Benzodiazepinones; Bismuth; Colloids; | 1985 |
Pirenzepine. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in peptic ulcer disease and other allied diseases.
Topics: Benzodiazepinones; Dialysis; Dyspepsia; Gastric Acid; Gastrins; Gastrointestinal Hormones; Humans; I | 1985 |
33 trials available for pirenzepine and Recrudescence
| Article | Year |
|---|---|
Open-label olanzapine in obsessive-compulsive disorder refractory to antidepressant treatment.
Topics: Adolescent; Adult; Antipsychotic Agents; Benzodiazepines; Dose-Response Relationship, Drug; Drug Adm | 2002 |
Measurement of simple reaction time in antipsychotic treatment of patients with schizophrenia.
Topics: Acute Disease; Adult; Antipsychotic Agents; Benzodiazepines; Double-Blind Method; Dyskinesia, Drug-I | 2003 |
[What is safe in conservative ulcer therapy? An evaluation of results from clinical studies].
Topics: Aluminum; Antacids; Benzodiazepinones; Carbenoxolone; Clinical Trials as Topic; Feeding Behavior; Hi | 1982 |
Seasonal prophylactic treatment with pirenzepine to prevent duodenal ulcer recurrence.
Topics: Benzodiazepinones; Clinical Trials as Topic; Double-Blind Method; Duodenal Ulcer; Humans; Pirenzepin | 1984 |
Sucralfate, bismuth compounds, substituted benzimidazoles, trimipramine and pirenzepine in the short- and long-term treatment of duodenal ulcer.
Topics: Aluminum; Animals; Antacids; Anti-Ulcer Agents; Benzimidazoles; Benzodiazepinones; Bismuth; Clinical | 1984 |
Long-term management of duodenal ulcer with pirenzepine and cimetidine: a double-blind controlled clinical trial.
Topics: Adult; Anti-Ulcer Agents; Benzodiazepinones; Clinical Trials as Topic; Double-Blind Method; Duodenal | 1983 |
Treatment and relapse prophylaxis of duodenal ulcer with pirenzepine and cimetidine.
Topics: Adult; Anti-Ulcer Agents; Benzodiazepinones; Cimetidine; Clinical Trials as Topic; Double-Blind Meth | 1982 |
Long-term treatment of duodenal ulcer with pirenzepine. A double-blind, placebo-controlled trial.
Topics: Adult; Anti-Ulcer Agents; Benzodiazepinones; Clinical Trials as Topic; Double-Blind Method; Duodenal | 1982 |
Maintenance treatment of recurrent duodenal ulceration with pirenzepine.
Topics: Adult; Aged; Anti-Ulcer Agents; Benzodiazepinones; Clinical Trials as Topic; Double-Blind Method; Du | 1980 |
[Treatment and prevention of recurrence of duodenal ulcer with pirenzepin and cimetidine].
Topics: Adult; Aged; Benzodiazepinones; Cimetidine; Clinical Trials as Topic; Duodenal Ulcer; Female; Guanid | 1982 |
Prevention of peptic ulcer relapse.
Topics: Cimetidine; Double-Blind Method; Humans; Life Tables; Peptic Ulcer; Pirenzepine; Proportional Hazard | 1994 |
Standard olanzapine versus placebo and ineffective-dose olanzapine in the maintenance treatment of schizophrenia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antipsychotic Agents; Benzodiazepines; Double-Blind Method; | 1997 |
The course of depressive symptoms in predicting relapse in schizophrenia: a double-blind, randomized comparison of olanzapine and risperidone.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Cluster Analysis; Cognition Disorders; Depressive Diso | 1999 |
Olanzapine as long-term adjunctive therapy in treatment-resistant bipolar disorder.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Disorders of Excessive Somnolence; D | 2001 |
Time to study discontinuation, relapse, and compliance with atypical or conventional antipsychotics in schizophrenia and related disorders.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Double-Blind Method; Female; Haloperidol; Humans; Male | 2002 |
Olanzapine augmentation in the treatment of melancholia: the trajectory of improvement in rapid responders.
Topics: Adult; Affect; Aged; Antipsychotic Agents; Anxiety; Benzodiazepines; Depressive Disorder; Disease Pr | 2002 |
Effect of drug therapy on the relapse of peptic ulcers. 1st communication: the effect of acute therapy.
Topics: Cimetidine; Double-Blind Method; Humans; Peptic Ulcer; Pirenzepine; Recurrence; Stomach Ulcer | 1992 |
Effect of drug therapy on the relapse of peptic ulcers. 2nd communication: the effect of maintenance therapy.
Topics: Cimetidine; Double-Blind Method; Humans; Peptic Ulcer; Pirenzepine; Recurrence | 1992 |
Predictors of relapse in peptic ulcer.
Topics: Adult; Cimetidine; Double-Blind Method; Female; Humans; Male; Peptic Ulcer; Pirenzepine; Prognosis; | 1992 |
[The differentiated treatment of patients with duodenal peptic ulcer].
Topics: Adult; Biopsy; Drug Evaluation; Duodenal Ulcer; Gastric Acid; Gastrins; Humans; Male; Pepsinogens; P | 1992 |
Maintenance therapy for duodenal ulcer: a randomized controlled comparison of seven forms of treatment.
Topics: Adult; Antacids; Cimetidine; Duodenal Ulcer; Endoscopy, Gastrointestinal; Female; Hong Kong; Hospita | 1992 |
Comparison of cimetidine and pirenzepine in the healing and maintenance of remission in duodenal ulcer.
Topics: Adult; Aged; Cimetidine; Duodenal Ulcer; Female; Humans; Male; Middle Aged; Pirenzepine; Recurrence; | 1990 |
Recurrence of duodenal ulcer after medical treatment.
Topics: Adult; Aged; Anti-Ulcer Agents; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Duodenal | 1988 |
[Pirenzepine and cimetidine in the treatment of duodenal ulcer].
Topics: Adult; Aged; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Duodenal Ulcer; Female; Gast | 1988 |
Treatment of Campylobacter pylori gastritis: a pilot study using pirenzepine dihydrochloride (Gastrozepin) and three formulations of colloidal bismuth subcitrate (De-Nol).
Topics: Administration, Oral; Adult; Biopsy; Bismuth; Campylobacter; Campylobacter Infections; Clinical Tria | 1988 |
Prevention of duodenal ulcer recurrence by pirenzepine 50 mg twice daily.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Duodenal Ulcer; Female; Humans; Male; Mi | 1987 |
A study on the prevention of duodenal ulcer recurrence with pirenzepine.
Topics: Adult; Aged; Clinical Trials as Topic; Duodenal Ulcer; Female; Humans; Male; Middle Aged; Pirenzepin | 1987 |
Prevention of relapse with various antiulcer drugs.
Topics: Adult; Antacids; Cimetidine; Clinical Trials as Topic; Duodenal Ulcer; Female; Humans; Male; Middle | 1986 |
Seasonal prevention of duodenal ulcer recurrences with pirenzepine.
Topics: Adult; Double-Blind Method; Drug Administration Schedule; Duodenal Ulcer; Female; Humans; Male; Pati | 1987 |
[Pharmacologic treatment of duodenal ulcer. Short and long-term results with pirenzepine in ambulatory patients].
Topics: Adult; Aged; Double-Blind Method; Duodenal Ulcer; Female; Follow-Up Studies; Gastric Acid; Humans; M | 1986 |
Is maximal acid output useful in identifying relapsing duodenal ulcer patients?
Topics: Adult; Aged; Benzodiazepinones; Cimetidine; Duodenal Ulcer; Female; Follow-Up Studies; Gastric Acid; | 1985 |
Treatment of duodenal ulcers using pirenzepine and cimetidine: controlled trial.
Topics: Adult; Anti-Ulcer Agents; Benzodiazepinones; Cimetidine; Clinical Trials as Topic; Duodenal Ulcer; F | 1985 |
[Recurrence of chronic duodenal ulcer following initial therapy with pirenzepine or cimetidine].
Topics: Adult; Aged; Benzodiazepinones; Chronic Disease; Cimetidine; Clinical Trials as Topic; Duodenal Ulce | 1985 |
24 other studies available for pirenzepine and Recrudescence
| Article | Year |
|---|---|
[Long-term therapy with intuition].
Topics: Acute Disease; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Clinical T | 2003 |
Recurrence of duodenal ulcer under continuous antisecretory treatment: an approach to the detection of predictive markers.
Topics: Adolescent; Adult; Alcohol Drinking; Anti-Ulcer Agents; Benzodiazepinones; Blood Group Antigens; Cim | 1984 |
Long-term treatment of duodenal ulcer with pirenzepine; gastric pH values and incidence of relapses: an open pilot study.
Topics: Adult; Aged; Anti-Ulcer Agents; Benzodiazepinones; Duodenal Ulcer; Female; Gastric Acidity Determina | 1983 |
[Treatment of peptic ulcer with gastrozepin].
Topics: Adult; Aged; Anti-Ulcer Agents; Benzodiazepinones; Chronic Disease; Drug Evaluation; Female; Humans; | 1984 |
Pirenzepine in long-term therapy for duodenal ulcer.
Topics: Adult; Aged; Antacids; Anti-Ulcer Agents; Benzodiazepinones; Cimetidine; Duodenal Ulcer; Female; Hum | 1983 |
[Retrospective study of the evaluation of peptic ulcer recurrence after 4 weeks of pirenzepin (Gastrozepin) treatment].
Topics: Benzodiazepinones; Humans; Peptic Ulcer; Pirenzepine; Recurrence; Retrospective Studies | 1983 |
[Treatment of stomach ulcer (review)].
Topics: Aluminum; Antacids; Benzodiazepinones; Bismuth; Carbenoxolone; Cimetidine; Feeding Behavior; Gastrec | 1982 |
[Gastrotsepin in the therapy and prevention of peptic ulcer exacerbations associated with Helicobacter pylori bacteriosis].
Topics: Drug Evaluation; Drug Therapy, Combination; Duodenal Ulcer; Helicobacter Infections; Helicobacter py | 1995 |
[High-dose omeprazole versus famotidine, pirenzepine and antacid in therapy of acute upper gastrointestinal hemorrhage in a retrospective comparison].
Topics: Aged; Aged, 80 and over; Aluminum Hydroxide; Antacids; Dose-Response Relationship, Drug; Drug Admini | 1994 |
A new diagnostic test for incomplete vagotomy: experimental study in dogs.
Topics: Animals; Diagnosis, Differential; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Duoden | 1993 |
Adjunctive use of olanzapine in mood disorders: five case reports.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Delusions; Depressive Disorder, Majo | 1997 |
Oral olanzapine versus oral haloperidol in the maintenance treatment of schizophrenia and related psychoses.
Topics: Administration, Oral; Adult; Antipsychotic Agents; Benzodiazepines; Double-Blind Method; Female; Hal | 1998 |
Hyperglycemia associated with olanzapine.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; | 1998 |
[Neuroleptic malignant syndrome: case report with recurrence associated with the use of olanzapine].
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Haloperidol; Humans; Male; Neuroleptic | 1998 |
Risperidone-induced tardive dystonia and psychosis.
Topics: Antipsychotic Agents; Benzodiazepines; Dystonia; Facial Muscles; Humans; Male; Middle Aged; Neck Mus | 1999 |
Early relapse of psychotic symptoms after an initial response to olanzapine.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Binding, Competitive; Brief Psychiatric Rating Scale; | 1999 |
Recurrence of neuroleptic malignant syndrome with olanzapine treatment.
Topics: Aged; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Chlorprothixene; Clopenthixol; Female | 1999 |
St. John's wort and schizophrenia.
Topics: Acute Disease; Adult; Antipsychotic Agents; Benzodiazepines; Female; Humans; Hypericum; Male; Olanza | 2000 |
Supersensitivity psychosis in patients with schizophrenia after sudden olanzapine withdrawal.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Humans; Male; Middle Aged; Olanzapine; Pirenzepine; Ps | 2001 |
Olanzapine-induced priapism.
Topics: Adult; Benzodiazepines; Erectile Dysfunction; Humans; Male; Olanzapine; Pirenzepine; Priapism; Psych | 2001 |
[Clinical problems in the treatment and physiopathology of peptic ulcer in the aged].
Topics: Adult; Age Factors; Aged; Humans; Middle Aged; Peptic Ulcer; Pirenzepine; Recurrence | 1991 |
[Comparative studies on recurrence and relapse rate in peptic ulcer treated with various types of anti-ulcer agent; inhibitors of initiating factors causing peptic ulcer].
Topics: Cimetidine; Histamine H2 Antagonists; Humans; Peptic Ulcer; Pirenzepine; Ranitidine; Recurrence | 1988 |
[Recent developments in drugs antagonistic to factors causing peptic ulcer--clinical efficacy and problems; muscarine M1 receptor blockaders].
Topics: Gastric Acid; Humans; Peptic Ulcer; Pirenzepine; Receptors, Muscarinic; Recurrence | 1988 |
Personality and duodenal ulcer response to antisecretory treatment.
Topics: Cimetidine; Duodenal Ulcer; Female; Humans; Male; Middle Aged; Personality; Personality Inventory; P | 1987 |