Page last updated: 2024-11-02

pirenzepine and Pregnancy

pirenzepine has been researched along with Pregnancy in 29 studies

Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"Both acute and chronic administration of N-methyl-D-aspartate (NMDA) receptor antagonists such as phencyclidine and dizocilpine have been proposed to mimic some of the symptoms of schizophrenia."7.71Long-term behavioral and neurodegenerative effects of perinatal phencyclidine administration: implications for schizophrenia. ( Johnson, KM; McInnis, J; Ross-Sanchez, M; Shinnick-Gallagher, P; Wang, C; Wiley, JL, 2001)
"Bethanechol induced smooth muscle contractions via muscarinic receptor subtype M3."3.74Corticotropin-releasing factor inhibition of sheep fetal colonic contractility: mechanisms to prevent meconium passage in utero. ( Ahanya, SA; Lakshmanan, J; Liu, G; Mazdak, M; Oyachi, N; Ross, MG, 2007)
"Prenatal nicotine exposure is associated with an increased risk of complications during pregnancy and childhood."3.73Smoking during early pregnancy affects the expression pattern of both nicotinic and muscarinic acetylcholine receptors in human first trimester brainstem and cerebellum. ( Falk, L; Hellström-Lindahl, E; Kjaeldgaard, A; Nordberg, A; Seiger, A, 2005)
"One of my patients is taking olanzapine for schizophrenia."3.71Maternal obesity and risk of neural tube defects. ( Koren, G, 2001)
"Both acute and chronic administration of N-methyl-D-aspartate (NMDA) receptor antagonists such as phencyclidine and dizocilpine have been proposed to mimic some of the symptoms of schizophrenia."3.71Long-term behavioral and neurodegenerative effects of perinatal phencyclidine administration: implications for schizophrenia. ( Johnson, KM; McInnis, J; Ross-Sanchez, M; Shinnick-Gallagher, P; Wang, C; Wiley, JL, 2001)
"Olanzapine is an 'atypical' antipsychotic indicated for the treatment of schizophrenia."3.71The pharmacovigilance of olanzapine: results of a post-marketing surveillance study on 8858 patients in England. ( Biswasl, PN; Freemantle, S; Pearcel, GL; Shakir, SA; Wilton, LV, 2001)
"We report a case of an idiopathic facial paralysis (Bell's palsy) in the immediate puerperium in a patient with mild preeclampsia and diagnosed fetal IUGR."1.33Idiopathic facial paralysis (Bell's palsy) in the immediate puerperium in a patient with mild preeclampsia: a case report. ( Friese, K; Kainer, F; Kästner, R; Mylonas, I; Sattler, C, 2005)
"Carbachol treatment of brain slices, in the presence of lithium, resulted in the accumulation of IPs."1.29Muscarinic receptor-dependent activation of phospholipase C in the developing human fetal central nervous system. ( Larocca, JN; Lyman, WD; Rashbaum, WK; Rodriguez-Gabin, AG; Weidenheim, KM, 1994)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.45)18.7374
1990's10 (34.48)18.2507
2000's18 (62.07)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rosengarten, H1
Quartermain, D1
Qiao, D1
Seidler, FJ1
Abreu-Villaça, Y1
Tate, CA1
Cousins, MM1
Slotkin, TA1
Abdel-Rahman, A1
Dechkovskaia, AM1
Mehta-Simmons, H1
Sutton, JM1
Guan, X1
Khan, WA1
Abou-Donia, MB1
Falk, L1
Nordberg, A1
Seiger, A1
Kjaeldgaard, A1
Hellström-Lindahl, E1
Mylonas, I1
Kästner, R1
Sattler, C1
Kainer, F1
Friese, K1
Lakshmanan, J1
Oyachi, N1
Ahanya, SA1
Liu, G1
Mazdak, M1
Ross, MG1
Larocca, JN1
Rodriguez-Gabin, AG1
Rashbaum, WK1
Weidenheim, KM1
Lyman, WD1
Bielarczyk, H1
Tomsig, JL1
Suszkiw, JB1
Jovanović, A1
Grbović, L1
Drekić, D1
Novaković, S1
Dickson, RA1
Dawson, DT1
Chay, SH1
Herman, JL1
Tayebati, SK1
Vitaioli, L1
Zaccheo, D1
Amenta, F1
Schenker, S1
Yang, Y1
Mattiuz, E1
Tatum, D1
Lee, M1
Kirchheiner, J1
Berghöfer, A1
Bolk-Weischedel, D1
Littrell, KH1
Johnson, CG1
Peabody, CD1
Hilligoss, N1
Goldstein, DJ1
Corbin, LA1
Fung, MC1
Nagy, A1
Tényi, T1
Lénárd, K1
Herold, R1
Wilhelm, F1
Trixler, M1
Iqbal, MM1
Gundlapalli, SP1
Ryan, WG1
Ryals, T1
Passman, TE1
Koren, G1
Malek-Ahmadi, P1
Wang, C1
McInnis, J1
Ross-Sanchez, M1
Shinnick-Gallagher, P1
Wiley, JL1
Johnson, KM1
Neumann, NU1
Frasch, K1
Biswasl, PN1
Wilton, LV1
Pearcel, GL1
Freemantle, S1
Shakir, SA1
Lim, LM1
Mendhekar, DN1
War, L1
Sharma, JB1
Jiloha, RC1
Drübbisch, V1
Lameh, J1
Philip, M1
Sharma, YK1
Sadée, W1
Fiszman, ML1
Barker, JL1
Jones, SV1
Nowak, J1

Reviews

1 review available for pirenzepine and Pregnancy

ArticleYear
Effects of antimanic mood-stabilizing drugs on fetuses, neonates, and nursing infants.
    Southern medical journal, 2001, Volume: 94, Issue:3

    Topics: Abnormalities, Drug-Induced; Acetates; Adult; Amines; Antimanic Agents; Benzodiazepines; Breast Feed

2001

Other Studies

28 other studies available for pirenzepine and Pregnancy

ArticleYear
Effect of prenatal administration of haloperidol, risperidone, quetiapine and olanzapine on spatial learning and retention in adult rats.
    Pharmacology, biochemistry, and behavior, 2002, Volume: 72, Issue:3

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain; Dibenzothiazepines; Drinking; Female; Haloper

2002
Chlorpyrifos exposure during neurulation: cholinergic synaptic dysfunction and cellular alterations in brain regions at adolescence and adulthood.
    Brain research. Developmental brain research, 2004, Jan-31, Volume: 148, Issue:1

    Topics: Acetyl Coenzyme A; Acetylcholine; Age Factors; Analysis of Variance; Animals; Binding Sites; Biomark

2004
Maternal exposure to nicotine and chlorpyrifos, alone and in combination, leads to persistently elevated expression of glial fibrillary acidic protein in the cerebellum of the offspring in late puberty.
    Archives of toxicology, 2004, Volume: 78, Issue:8

    Topics: Alkaloids; Animals; Azocines; Bungarotoxins; Cerebellum; Chlorpyrifos; Cholinesterases; Drug Synergi

2004
Smoking during early pregnancy affects the expression pattern of both nicotinic and muscarinic acetylcholine receptors in human first trimester brainstem and cerebellum.
    Neuroscience, 2005, Volume: 132, Issue:2

    Topics: Alkaloids; Azocines; Brain Stem; Cerebellum; Female; Fetus; Gene Expression Regulation, Developmenta

2005
Idiopathic facial paralysis (Bell's palsy) in the immediate puerperium in a patient with mild preeclampsia: a case report.
    Archives of gynecology and obstetrics, 2005, Volume: 272, Issue:3

    Topics: Acyclovir; Adult; Bell Palsy; Cesarean Section; Cheek; Female; Glucocorticoids; Humans; Methylpredni

2005
Corticotropin-releasing factor inhibition of sheep fetal colonic contractility: mechanisms to prevent meconium passage in utero.
    American journal of obstetrics and gynecology, 2007, Volume: 196, Issue:4

    Topics: Animals; Bethanechol; Colon; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fetus

2007
Muscarinic receptor-dependent activation of phospholipase C in the developing human fetal central nervous system.
    Brain research, 1994, Aug-08, Volume: 653, Issue:1-2

    Topics: Atropine; Brain; Carbachol; Cytidine Diphosphate Diglycerides; Embryonic and Fetal Development; Enzy

1994
Perinatal low-level lead exposure and the septo-hippocampal cholinergic system: selective reduction of muscarinic receptors and cholineacetyltransferase in the rat septum.
    Brain research, 1994, Apr-18, Volume: 643, Issue:1-2

    Topics: Aging; Animals; Brain; Choline O-Acetyltransferase; Embryonic and Fetal Development; Female; Glutama

1994
Muscarinic receptor function in the guinea-pig uterine artery is not altered during pregnancy.
    European journal of pharmacology, 1994, Jun-13, Volume: 258, Issue:3

    Topics: Acetylcholine; Animals; Arteries; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; G

1994
Olanzapine and pregnancy.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1998, Volume: 43, Issue:2

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Female; Humans; Olanzapine; Pirenzepine; Pregnancy; Pr

1998
Disposition of the novel anti-schizophrenic drug [14C]olanzapine in male Fischer 344 and female CD rats following single oral dose administration.
    Arzneimittel-Forschung, 1998, Volume: 48, Issue:5

    Topics: Animals; Antipsychotic Agents; Area Under Curve; Autoradiography; Benzodiazepines; Female; Image Pro

1998
Autoradiographic localisation of muscarinic cholinergic receptor subtypes in human placenta.
    Neuroscience letters, 1998, May-15, Volume: 247, Issue:2-3

    Topics: Adult; Binding, Competitive; Diamines; Female; Humans; Microvilli; Muscarinic Antagonists; Piperidin

1998
[Schizophrenia and depression. Special aspects in the therapy of women].
    Der Nervenarzt, 1998, Volume: 69, Issue:7 Suppl Be

    Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Depressive Disorder; Female; Humans; Olanzapine; P

1998
Olanzapine transfer by human placenta.
    Clinical and experimental pharmacology & physiology, 1999, Volume: 26, Issue:9

    Topics: Antipsychotic Agents; Benzodiazepines; Female; Glucuronides; Humans; Maternal-Fetal Exchange; Olanza

1999
Healthy outcome under olanzapine treatment in a pregnant woman.
    Pharmacopsychiatry, 2000, Volume: 33, Issue:2

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Breast Feeding; Female; Humans; Infant, Newborn; Mater

2000
Antipsychotics during pregnancy.
    The American journal of psychiatry, 2000, Volume: 157, Issue:8

    Topics: Antipsychotic Agents; Benzodiazepines; Female; Humans; Olanzapine; Pirenzepine; Pregnancy; Pregnancy

2000
Olanzapine-exposed pregnancies and lactation: early experience.
    Journal of clinical psychopharmacology, 2000, Volume: 20, Issue:4

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Adult; Antipsychotic Agents; Benzodiazepines; Cl

2000
[Olanzapine and pregnancy].
    Orvosi hetilap, 2001, Jan-21, Volume: 142, Issue:3

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Female; Humans; Olanzapine; Pirenzepine; Pregnancy; Pr

2001
Maternal obesity and risk of neural tube defects.
    Canadian family physician Medecin de famille canadien, 2001, Volume: 47

    Topics: Antipsychotic Agents; Benzodiazepines; Female; Folic Acid; Humans; Infant, Newborn; Neural Tube Defe

2001
Olanzapine in pregnancy.
    The Annals of pharmacotherapy, 2001, Volume: 35, Issue:10

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Female; Humans; Infant, Newborn; Male; Olanzapine; Pir

2001
Long-term behavioral and neurodegenerative effects of perinatal phencyclidine administration: implications for schizophrenia.
    Neuroscience, 2001, Volume: 107, Issue:4

    Topics: Animals; Antipsychotic Agents; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Behavior, Anima

2001
[Olanzapine and pregnancy. 2 case reports].
    Der Nervenarzt, 2001, Volume: 72, Issue:11

    Topics: Adult; Benzodiazepines; Female; Follow-Up Studies; Humans; Infant, Newborn; Male; Olanzapine; Pirenz

2001
The pharmacovigilance of olanzapine: results of a post-marketing surveillance study on 8858 patients in England.
    Journal of psychopharmacology (Oxford, England), 2001, Volume: 15, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antipsychotic Agents; Benzodiazepines; Chil

2001
Olanzapine and pregnancy.
    The Australian and New Zealand journal of psychiatry, 2001, Volume: 35, Issue:6

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Female; Humans; Olanzapine; Pirenzepine; Pregnancy

2001
Olanzapine and pregnancy.
    Pharmacopsychiatry, 2002, Volume: 35, Issue:3

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Female; Humans; Olanzapine; Pirenzepine; Pregnancy; Pr

2002
Mapping the ligand binding pocket of the human muscarinic cholinergic receptor Hm1: contribution of tyrosine-82.
    Pharmaceutical research, 1992, Volume: 9, Issue:12

    Topics: Amino Acid Sequence; Binding, Competitive; Cells, Cultured; Female; GTP-Binding Proteins; Humans; Ki

1992
Electrophysiological responses to muscarinic receptor stimulation in cultured hippocampal neurons.
    Brain research, 1991, Aug-23, Volume: 557, Issue:1-2

    Topics: Action Potentials; Animals; Atropine; Carbachol; Cells, Cultured; Electrophysiology; Female; Hippoca

1991
[Selective use of the muscarinic receptor blockader gastrozepine in preventing Mendelson's syndrome in obstetrics].
    Ginekologia polska, 1986, Volume: 57, Issue:12

    Topics: Adolescent; Adult; Anesthesia, Obstetrical; Female; Humans; Intraoperative Complications; Parasympat

1986