pirenzepine has been researched along with Pheochromocytoma in 5 studies
Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.
Pheochromocytoma: A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)
Excerpt | Relevance | Reference |
---|---|---|
"The high affinity binding of the muscarinic ligand 3H-N-methylscopolamine (3H-NMS) to intact cells of the rat pheochromocytoma cell line PC12 was studied." | 3.67 | Muscarinic cholinergic receptors in a rat phaeochromocytoma cell line. ( Cross, AJ; Frith, C; Johnson, JA; Taylor, GR, 1984) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 5 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Cross, AJ | 1 |
Johnson, JA | 1 |
Frith, C | 1 |
Taylor, GR | 1 |
Horwitz, J | 1 |
Takashima, A | 1 |
Kenimer, JG | 1 |
Michel, AD | 1 |
Stefanich, E | 1 |
Whiting, RL | 1 |
Gatti, G | 1 |
Madeddu, L | 1 |
Pandiella, A | 1 |
Pozzan, T | 1 |
Meldolesi, J | 1 |
5 other studies available for pirenzepine and Pheochromocytoma
Article | Year |
---|---|
Muscarinic cholinergic receptors in a rat phaeochromocytoma cell line.
Topics: Animals; Benzodiazepinones; Cell Line; N-Methylscopolamine; Pheochromocytoma; Pirenzepine; Rats; Rec | 1984 |
Muscarinic receptor stimulation increases inositol-phospholipid metabolism and inhibits cyclic AMP accumulation in PC12 cells.
Topics: Animals; Cyclic AMP; Muscarine; N-Methylscopolamine; Pheochromocytoma; Phorbol Esters; Phosphatidyli | 1989 |
Muscarinic-stimulated norepinephrine release and phosphoinositide hydrolysis in PC12 cells are independent events.
Topics: Adrenal Gland Neoplasms; Animals; Atropine; Cell Line; Diamines; Hydrolysis; Kinetics; Methacholine | 1989 |
PC12 phaeochromocytoma cells contain an atypical muscarinic receptor binding site.
Topics: Adrenal Gland Neoplasms; Animals; Binding, Competitive; Cell Membrane; Kinetics; Myocardium; N-Methy | 1989 |
Second-messenger generation in PC12 cells. Interactions between cyclic AMP and Ca2+ signals.
Topics: Animals; Calcium; Carbachol; Cell Differentiation; Cell Line; Clonidine; Cyclic AMP; Imidazoles; Ner | 1988 |