pirenzepine has been researched along with Neoplasms in 5 studies
Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This open-label pilot study explored the antiemetic activity of olanzapine, an atypical antipsychotic, in patients with advanced cancer requiring opioid analgesics for pain." | 7.71 | A pilot exploration of the antiemetic activity of olanzapine for the relief of nausea in patients with advanced cancer and pain. ( Cooper, M; Donaghy, K; Dugan, W; Holtsclaw, E; Kirsh, KL; Lundberg, J; Passik, SD; Theobald, D, 2002) |
| "Olanzapine, which has been used anecdotally for chronic nausea in advanced cancer patients, might be a useful treatment for the prevention of delayed emesis in chemotherapy patients." | 5.32 | A retrospective chart review of the use of olanzapine for the prevention of delayed emesis in cancer patients. ( Beaver, M; Brown, J; Comparet, J; Dickerson, P; Gray, D; Kirsh, KL; Passik, SD; Theobald, DE; Trowbridge, R, 2003) |
| "This open-label pilot study explored the antiemetic activity of olanzapine, an atypical antipsychotic, in patients with advanced cancer requiring opioid analgesics for pain." | 3.71 | A pilot exploration of the antiemetic activity of olanzapine for the relief of nausea in patients with advanced cancer and pain. ( Cooper, M; Donaghy, K; Dugan, W; Holtsclaw, E; Kirsh, KL; Lundberg, J; Passik, SD; Theobald, D, 2002) |
| "Advanced cancer patients are polysymptomatic and often receive multiple medications for symptom relief." | 2.41 | Management of symptoms associated with advanced cancer: olanzapine and mirtazapine. A World Health Organization project. ( Davis, MP; Khawam, E; Lagman, R; Pozuelo, L, 2002) |
| "Olanzapine, which has been used anecdotally for chronic nausea in advanced cancer patients, might be a useful treatment for the prevention of delayed emesis in chemotherapy patients." | 1.32 | A retrospective chart review of the use of olanzapine for the prevention of delayed emesis in cancer patients. ( Beaver, M; Brown, J; Comparet, J; Dickerson, P; Gray, D; Kirsh, KL; Passik, SD; Theobald, DE; Trowbridge, R, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davis, MP | 1 |
| Khawam, E | 1 |
| Pozuelo, L | 1 |
| Lagman, R | 1 |
| Passik, SD | 2 |
| Kirsh, KL | 2 |
| Theobald, DE | 1 |
| Dickerson, P | 1 |
| Trowbridge, R | 1 |
| Gray, D | 1 |
| Beaver, M | 1 |
| Comparet, J | 1 |
| Brown, J | 1 |
| Carrillo, JA | 1 |
| BenÃtez, J | 1 |
| Khojainova, N | 1 |
| Santiago-Palma, J | 1 |
| Kornick, C | 1 |
| Breitbart, W | 1 |
| Gonzales, GR | 1 |
| Lundberg, J | 1 |
| Theobald, D | 1 |
| Donaghy, K | 1 |
| Holtsclaw, E | 1 |
| Cooper, M | 1 |
| Dugan, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Olanzapine as First Line Treatment for Prevention of Nausea and Vomiting Induced by Chemotherapy of Lung Cancer: a Multicenter, Double-blind and Randomized Trial[NCT03571126] | Phase 4 | 156 participants (Anticipated) | Interventional | 2019-05-09 | Recruiting | ||
| Aprepitant- and Olanzapine- Containing Regimens for Prevention of Acute and Delayed Nausea and Vomiting Associated With High Dose Melphalan and BEAM in Autologous Stem Cell Transplant Patients[NCT02939287] | Phase 3 | 429 participants (Actual) | Interventional | 2017-09-23 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for pirenzepine and Neoplasms
| Article | Year |
|---|---|
Management of symptoms associated with advanced cancer: olanzapine and mirtazapine. A World Health Organization project.
Topics: Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Drug Interactions; Humans; Mianserin; | 2002 |
1 trial available for pirenzepine and Neoplasms
| Article | Year |
|---|---|
Olanzapine in the management of cancer pain.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Benzodiazepines; Female; Humans; Male; Middle Aged; N | 2002 |
3 other studies available for pirenzepine and Neoplasms
| Article | Year |
|---|---|
A retrospective chart review of the use of olanzapine for the prevention of delayed emesis in cancer patients.
Topics: Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Agents; Benzodiazepines; Female; Humans; | 2003 |
Are antipsychotic drugs potentially chemopreventive agents for cancer?
Topics: Adult; Antineoplastic Agents; Antipsychotic Agents; Benzodiazepines; Caffeine; Carcinogens; Chemopre | 1999 |
A pilot exploration of the antiemetic activity of olanzapine for the relief of nausea in patients with advanced cancer and pain.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiemetics; Benzodiazepines; Dyskinesia, Drug-Induced; | 2002 |