pirenzepine has been researched along with Necrosis in 5 studies
Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In order to evaluate the possible involvement of muscarinic cholinergic receptors in the GH response to TRH in patients with liver cirrhosis, 8 males with post-hepatitic cirrhosis and 11 males with post-alcoholic cirrhosis were primed with the anticholinergic agent pirenzepine and tested with TRH." | 3.67 | Cholinergic mediation of growth hormone secretion induced by thyrotropin-releasing hormone in cirrhotic patients. ( Cerri, L; Chiodera, P; Coiro, V; d'Amato, L; Delsignore, R; Ferrari, P; Pedretti, G; Roberti, G; Salati, G; Volpi, R, 1987) |
| "Cell necrosis was followed by loss of surfactant and formation of hyaline membranes, rich in immunoglobulin M." | 1.27 | The gastric juice aspiration syndrome (Mendelson syndrome). Aspects of pathogenesis and treatment in the pig. ( Juettner, F; Pinter, J; Popper, H, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kosaka, N | 1 |
| Tanaka, H | 1 |
| Tomaru, A | 1 |
| Ishii, A | 1 |
| Shuto, K | 1 |
| Boye, T | 1 |
| Carsuzaa, F | 1 |
| Popper, H | 1 |
| Juettner, F | 1 |
| Pinter, J | 1 |
| Volpi, R | 1 |
| Chiodera, P | 1 |
| Cerri, L | 1 |
| Roberti, G | 1 |
| Salati, G | 1 |
| Ferrari, P | 1 |
| Delsignore, R | 1 |
| Pedretti, G | 1 |
| d'Amato, L | 1 |
| Coiro, V | 1 |
| Takeda, F | 1 |
| Kitagawa, H | 1 |
| Kohei, H | 1 |
5 other studies available for pirenzepine and Necrosis
| Article | Year |
|---|---|
Effects of KW-5805, a new antiulcer agent, on experimental gastric and duodenal ulcers, gastric mucosal lesions by necrotizing agents and gastric acid secretion.
Topics: Animals; Anti-Ulcer Agents; Benzoxepins; Cimetidine; Depression, Chemical; Duodenal Ulcer; Ethanol; | 1994 |
[Bullae induced by acute neuroleptic intoxication].
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Drug Hypersensitivity; Eccrine Glands; Humans; Male; N | 2000 |
The gastric juice aspiration syndrome (Mendelson syndrome). Aspects of pathogenesis and treatment in the pig.
Topics: Anesthesia, General; Animals; Benzodiazepinones; Buffers; Fluorescent Antibody Technique; Gastric Ju | 1986 |
Cholinergic mediation of growth hormone secretion induced by thyrotropin-releasing hormone in cirrhotic patients.
Topics: Adult; Growth Hormone; Humans; Liver; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Male; Middle Aged | 1987 |
Gastric cytoprotection by pirenzepine in rats: evaluating method for cytoprotective activity by antisecretory agents.
Topics: Animals; Anti-Ulcer Agents; Atropine; Benzodiazepinones; Buffers; Cimetidine; Dinoprostone; Ethanol; | 1985 |