pirenzepine has been researched along with Myocardial Ischemia in 3 studies
Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pirenzepine is an atropine analogue approved to treat peptic ulcer disease in Europe that is devoid of central actions, which are mostly responsible for anti-muscarinic agents side effects." | 5.32 | Autonomic modulation during acute myocardial ischemia by low-dose pirenzepine in conscious dogs with a healed myocardial infarction: a comparison with beta-adrenergic blockade. ( Adamson, PB; Foreman, RD; Pedretti, RF; Prete, G; Vanoli, E, 2003) |
| "Pirenzepine is an atropine analogue approved to treat peptic ulcer disease in Europe that is devoid of central actions, which are mostly responsible for anti-muscarinic agents side effects." | 1.32 | Autonomic modulation during acute myocardial ischemia by low-dose pirenzepine in conscious dogs with a healed myocardial infarction: a comparison with beta-adrenergic blockade. ( Adamson, PB; Foreman, RD; Pedretti, RF; Prete, G; Vanoli, E, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pedretti, RF | 1 |
| Prete, G | 1 |
| Foreman, RD | 1 |
| Adamson, PB | 1 |
| Vanoli, E | 1 |
| Haunstetter, A | 1 |
| Haass, M | 1 |
| Yi, X | 1 |
| Krüger, C | 1 |
| Kübler, W | 1 |
| Lyzohub, VH | 1 |
| Pliskevyvch, DA | 1 |
| Nikoliuk, LS | 1 |
| Savchenko, OV | 1 |
3 other studies available for pirenzepine and Myocardial Ischemia
| Article | Year |
|---|---|
Autonomic modulation during acute myocardial ischemia by low-dose pirenzepine in conscious dogs with a healed myocardial infarction: a comparison with beta-adrenergic blockade.
Topics: Acute Disease; Adrenergic beta-Antagonists; Animals; Atenolol; Dogs; Dose-Response Relationship, Dru | 2003 |
Muscarinic inhibition of cardiac norepinephrine and neuropeptide Y release during ischemia and reperfusion.
Topics: Animals; Atropine; Carbachol; Electric Stimulation; Guinea Pigs; Heart; Male; Myocardial Ischemia; M | 1994 |
[Gastrozepin therapy of gallbladder motility disorders in patients with ischemic heart disease].
Topics: Adult; Angina Pectoris; Anti-Ulcer Agents; Gallbladder Diseases; Gallbladder Emptying; Humans; Incid | 2002 |