pirenzepine has been researched along with Morphine Abuse in 3 studies
Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The morphine (Antinociception) tolerance was assessed by using hot-plate latency, and morphine dependence was characterized by naloxone-precipitated withdrawal." | 3.69 | [Experimental study of selective muscarinic receptor antagonists on attenuation of morphine tolerance and dependence in rats]. ( Yang, G; Zhang, F; Zhou, W, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, G | 1 |
| Zhou, W | 1 |
| Zhang, F | 1 |
| Zhang, LC | 2 |
| Buccafusco, JJ | 2 |
3 other studies available for pirenzepine and Morphine Abuse
| Article | Year |
|---|---|
[Experimental study of selective muscarinic receptor antagonists on attenuation of morphine tolerance and dependence in rats].
Topics: Animals; Diamines; Drug Tolerance; Male; Morphine; Morphine Dependence; Muscarinic Antagonists; Pire | 1997 |
Prevention of morphine-induced muscarinic (M2) receptor adaptation suppresses the expression of withdrawal symptoms.
Topics: Animals; Behavior, Animal; Blood Pressure; Body Weight; Disease Models, Animal; Infusions, Intraveno | 1998 |
Adaptive changes in M1 muscarinic receptors localized to specific rostral brain regions during and after morphine withdrawal.
Topics: Animals; Autoradiography; Binding, Competitive; Blood Pressure; Body Weight; Brain; Isoflurophate; M | 2000 |