Page last updated: 2024-11-02

pirenzepine and Morphine Abuse

pirenzepine has been researched along with Morphine Abuse in 3 studies

Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.

Research Excerpts

ExcerptRelevanceReference
"The morphine (Antinociception) tolerance was assessed by using hot-plate latency, and morphine dependence was characterized by naloxone-precipitated withdrawal."3.69[Experimental study of selective muscarinic receptor antagonists on attenuation of morphine tolerance and dependence in rats]. ( Yang, G; Zhang, F; Zhou, W, 1997)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yang, G1
Zhou, W1
Zhang, F1
Zhang, LC2
Buccafusco, JJ2

Other Studies

3 other studies available for pirenzepine and Morphine Abuse

ArticleYear
[Experimental study of selective muscarinic receptor antagonists on attenuation of morphine tolerance and dependence in rats].
    Zhonghua yi xue za zhi, 1997, Volume: 77, Issue:2

    Topics: Animals; Diamines; Drug Tolerance; Male; Morphine; Morphine Dependence; Muscarinic Antagonists; Pire

1997
Prevention of morphine-induced muscarinic (M2) receptor adaptation suppresses the expression of withdrawal symptoms.
    Brain research, 1998, Aug-24, Volume: 803, Issue:1-2

    Topics: Animals; Behavior, Animal; Blood Pressure; Body Weight; Disease Models, Animal; Infusions, Intraveno

1998
Adaptive changes in M1 muscarinic receptors localized to specific rostral brain regions during and after morphine withdrawal.
    Neuropharmacology, 2000, Jul-24, Volume: 39, Issue:10

    Topics: Animals; Autoradiography; Binding, Competitive; Blood Pressure; Body Weight; Brain; Isoflurophate; M

2000