pirenzepine has been researched along with Liver Dysfunction in 1 studies
Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Plasma concentrations remained in the therapeutic range and the dosage regimen was well tolerated." | 1.28 | Steady-state intravenous pharmacokinetics of pirenzepine in patients with hepatic insufficiency and combined renal- and hepatic insufficiency. ( Bozler, G; Krakamp, B; Leidig, P; Schmitz, R; Tanswell, P; Vogel, H, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Krakamp, B | 1 |
| Tanswell, P | 1 |
| Leidig, P | 1 |
| Vogel, H | 1 |
| Schmitz, R | 1 |
| Bozler, G | 1 |
1 other study available for pirenzepine and Liver Dysfunction
| Article | Year |
|---|---|
Steady-state intravenous pharmacokinetics of pirenzepine in patients with hepatic insufficiency and combined renal- and hepatic insufficiency.
Topics: Adult; Aged; Chronic Disease; Female; Half-Life; Humans; Kidney Diseases; Liver Cirrhosis; Liver Dis | 1989 |