pirenzepine has been researched along with Lewy Body Disease in 7 studies
Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.
Lewy Body Disease: A neurodegenerative disease characterized by dementia, mild parkinsonism, and fluctuations in attention and alertness. The neuropsychiatric manifestations tend to precede the onset of bradykinesia, MUSCLE RIGIDITY, and other extrapyramidal signs. DELUSIONS and visual HALLUCINATIONS are relatively frequent in this condition. Histologic examination reveals LEWY BODIES in the CEREBRAL CORTEX and BRAIN STEM. SENILE PLAQUES and other pathologic features characteristic of ALZHEIMER DISEASE may also be present. (From Neurology 1997;48:376-380; Neurology 1996;47:1113-1124)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Psychosis was assessed with the Neuropsychiatric Inventory/Nursing Home (NPI-NH) version and the Brief Psychiatric Rating Scale (BPRS)." | 2.70 | Efficacy of olanzapine in the treatment of psychosis in dementia with lewy bodies. ( Clark, WS; Cummings, JL; Masterman, D; Street, J, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Friedman, JH | 1 |
| Fernandez, HH | 1 |
| Scheepmaker, AJ | 1 |
| Horstink, MW | 1 |
| Hoefnagels, WH | 1 |
| Strijks, FE | 1 |
| Piggott, MA | 1 |
| Owens, J | 1 |
| O'Brien, J | 1 |
| Colloby, S | 1 |
| Fenwick, J | 1 |
| Wyper, D | 1 |
| Jaros, E | 1 |
| Johnson, M | 1 |
| Perry, RH | 1 |
| Perry, EK | 1 |
| Hoeh, N | 1 |
| Gyulai, L | 1 |
| Weintraub, D | 1 |
| Streim, J | 1 |
| Simard, M | 1 |
| van Reekum, R | 1 |
| Cummings, JL | 1 |
| Street, J | 1 |
| Masterman, D | 1 |
| Clark, WS | 1 |
| Baldwin, SH | 1 |
| Avery, E | 1 |
3 reviews available for pirenzepine and Lewy Body Disease
| Article | Year |
|---|---|
Atypical antipsychotics in Parkinson-sensitive populations.
Topics: Alzheimer Disease; Antipsychotic Agents; Benzodiazepines; Clozapine; Dementia, Vascular; Dibenzothia | 2002 |
Pharmacologic management of psychosis in the elderly: a critical review.
Topics: Aged; Alzheimer Disease; Benzodiazepines; Bipolar Disorder; Clozapine; Depressive Disorder; Drug Adm | 2003 |
Dementia with Lewy bodies in Down's syndrome.
Topics: Adolescent; Adult; Aged; Alzheimer Disease; Antipsychotic Agents; Benzodiazepines; Comorbidity; Depr | 2001 |
1 trial available for pirenzepine and Lewy Body Disease
| Article | Year |
|---|---|
Efficacy of olanzapine in the treatment of psychosis in dementia with lewy bodies.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Behavior; Benzodiazepines; Cognition; Delusions; Dose | 2002 |
3 other studies available for pirenzepine and Lewy Body Disease
| Article | Year |
|---|---|
[Dementia with Lewy bodies; 2 patients with exacerbation due to an atypical antipsychotic, but with a favorable response to the cholinesterase inhibitor rivastigmine].
Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Antipsychotic Agents; Benzodiazepines; Carbamates; Ch | 2003 |
Muscarinic receptors in basal ganglia in dementia with Lewy bodies, Parkinson's disease and Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Autoradiography; Basal Ganglia; Cerebral Cortex; Female; Gyrus Cinguli; Hum | 2003 |
Lewy body dementia.
Topics: Aged; Benzodiazepines; Female; Humans; Lewy Body Disease; Olanzapine; Pirenzepine; Selective Seroton | 2002 |