pirenzepine has been researched along with Leukopenia in 7 studies
Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.
Leukopenia: A decrease in the number of LEUKOCYTES in a blood sample below the normal range (LEUKOCYTE COUNT less than 4000).
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report a 2-year experience with olanzapine treatment (20 mg daily) in a 65-year-old male patient with treatment-resistant paranoid schizophrenia, who had previously developed leucopenia and neutropenia first on clozapine and, subsequently, also on risperidone." | 3.70 | Olanzapine appears haematologically safe in patients who developed blood dyscrasia on clozapine and risperidone. ( Dernovsek, MZ; Tavcar, R, 2000) |
| "Four patients affected by severe Parkinson's disease developed leucopenia (900-1200 WBC) during treatment of psychosis (3) or untreatable insomnia (1) with clozapine (37." | 1.31 | Leucopenia induced by low dose clozapine in Parkinson's disease recedes shortly after drug withdrawal. Clinical case descriptions with commentary on switch-over to olanzapine. ( Bonanni, L; Gambi, F; Iacono, D; Onofrj, M; Thomas, A, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 6 (85.71) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Meissner, W | 1 |
| Schmidt, T | 1 |
| Kupsch, A | 1 |
| Trottenberg, T | 1 |
| Lempert, T | 1 |
| Dernovsek, MZ | 1 |
| Tavcar, R | 1 |
| Okajima, K | 1 |
| Murakami, K | 1 |
| Liu, W | 1 |
| Uchiba, M | 1 |
| Gram, LF | 1 |
| Onofrj, M | 1 |
| Thomas, A | 1 |
| Bonanni, L | 1 |
| Iacono, D | 1 |
| Gambi, F | 1 |
| Kodesh, A | 1 |
| Finkel, B | 1 |
| Lerner, AG | 1 |
| Kretzmer, G | 1 |
| Sigal, M | 1 |
| Jackson, RS | 1 |
7 other studies available for pirenzepine and Leukopenia
| Article | Year |
|---|---|
Reversible leucopenia related to olanzapine.
Topics: Benzodiazepines; Female; Humans; Leukopenia; Male; Middle Aged; Olanzapine; Pirenzepine; Psychotic D | 1999 |
Olanzapine appears haematologically safe in patients who developed blood dyscrasia on clozapine and risperidone.
Topics: Aged; Antipsychotic Agents; Benzodiazepines; Clozapine; Drug Monitoring; Humans; Leukopenia; Male; N | 2000 |
Inhibition of neutrophil activation by ranitidine contributes to prevent stress-induced gastric mucosal injury in rats.
Topics: Animals; Calcium; Cells, Cultured; E-Selectin; Endothelium, Vascular; Gastric Mucosa; Histamine H2 A | 2000 |
[Is bone marrow inhibition a special risk in connection with olanzapine (Zyprexa) treatment?].
Topics: Adolescent; Adult; Antipsychotic Agents; Benzodiazepines; Bone Marrow; Female; Humans; Leukocyte Cou | 2000 |
Leucopenia induced by low dose clozapine in Parkinson's disease recedes shortly after drug withdrawal. Clinical case descriptions with commentary on switch-over to olanzapine.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Benzodiazepines; Clozapine; Dose-Response Relationshi | 2000 |
Dose-dependent olanzapine-associated leukopenia: three case reports.
Topics: Adolescent; Adult; Antipsychotic Agents; Benzodiazepines; Dose-Response Relationship, Drug; Female; | 2001 |
Continuing treatment with novel antipsychotic drugs despite leukopenia or thrombocytopenia.
Topics: Antipsychotic Agents; Benzodiazepines; Female; Humans; Leukocyte Count; Leukopenia; Middle Aged; Ola | 2001 |