pirenzepine has been researched along with Kidney Failure, Chronic in 4 studies
Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The pharmacokinetic properties of pirenzepine following administration of a single, 50 mg oral dose were evaluated in three groups of subjects: group I, end stage renal disease requiring maintenance haemodialysis (CLCR 0 to 10 ml." | 1.28 | Oral pharmacokinetics of pirenzepine in patients with chronic renal insufficiency, failure, and maintenance haemodialysis. ( Chonko, A; Keirns, J; MacGregor, T; Matzek, K; Vinocur, M, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fukunishi, I | 1 |
| Sato, Y | 1 |
| Kino, K | 1 |
| Shirai, T | 1 |
| Kitaoka, T | 1 |
| Minar, E | 1 |
| Zazgornik, J | 1 |
| Dudczak, R | 1 |
| Marosi, L | 1 |
| Díez, JJ | 1 |
| Iglesias, P | 1 |
| Aguilera, A | 1 |
| Bajo, MA | 1 |
| Selgas, R | 1 |
| MacGregor, T | 1 |
| Matzek, K | 1 |
| Keirns, J | 1 |
| Vinocur, M | 1 |
| Chonko, A | 1 |
2 trials available for pirenzepine and Kidney Failure, Chronic
| Article | Year |
|---|---|
Effect of combination therapy with cimetidine and pirenzepine on plasma parathyroid hormone and calcitonin levels in hemodialyzed patients.
Topics: Adolescent; Adult; Aged; Benzodiazepinones; Calcitonin; Cimetidine; Drug Therapy, Combination; Femal | 1984 |
Effects of cholinergic muscarinic blockade on growth hormone responses to growth hormone-releasing hormone in uraemic patients.
Topics: Administration, Oral; Adult; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Kidney | 1999 |
2 other studies available for pirenzepine and Kidney Failure, Chronic
| Article | Year |
|---|---|
Hypothermia in a hemodialysis patient treated with olanzapine monotherapy.
Topics: Benzodiazepines; Humans; Hypothermia; Kidney Failure, Chronic; Male; Middle Aged; Olanzapine; Pirenz | 2003 |
Oral pharmacokinetics of pirenzepine in patients with chronic renal insufficiency, failure, and maintenance haemodialysis.
Topics: Administration, Oral; Adult; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Pirenzepine | 1990 |