pirenzepine has been researched along with Inflammation in 4 studies
Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Carbachol-induced contraction of the rat colon is impaired in rats with trinitrobenzene sulfonic acid (TNBS)-induced colitis." | 7.77 | Colonic inflammation increases the contribution of muscarinic M2 receptors to carbachol-induced contraction of the rat colon. ( Jragh, DM; Khan, I; Oriowo, MA, 2011) |
| "Carbachol-induced contraction of the rat colon is impaired in rats with trinitrobenzene sulfonic acid (TNBS)-induced colitis." | 3.77 | Colonic inflammation increases the contribution of muscarinic M2 receptors to carbachol-induced contraction of the rat colon. ( Jragh, DM; Khan, I; Oriowo, MA, 2011) |
| " The M1 receptor agonists aceclidine and arecholine and the nonspecific muscarinic receptor agonist oxotremorine augmented carrageenin oedema, an effect attenuated by the M1 receptor antagonist scopolamine." | 3.68 | Central muscarinic receptor subtypes and carrageenin-induced paw oedema in rats. ( Bhattacharya, SK; Das Gupta, G; Sen, AP; Seth, K; Seth, PK, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jragh, DM | 1 |
| Khan, I | 1 |
| Oriowo, MA | 1 |
| Motta, PG | 1 |
| Perez, AC | 1 |
| Alves, DP | 1 |
| Duarte, ID | 1 |
| Yoon, SY | 1 |
| Kim, HW | 1 |
| Roh, DH | 1 |
| Kwon, YB | 1 |
| Jeong, TO | 1 |
| Han, HJ | 1 |
| Lee, HJ | 1 |
| Choi, SM | 1 |
| Ryu, YH | 1 |
| Beitz, AJ | 1 |
| Lee, JH | 1 |
| Bhattacharya, SK | 1 |
| Sen, AP | 1 |
| Das Gupta, G | 1 |
| Seth, K | 1 |
| Seth, PK | 1 |
4 other studies available for pirenzepine and Inflammation
| Article | Year |
|---|---|
Colonic inflammation increases the contribution of muscarinic M2 receptors to carbachol-induced contraction of the rat colon.
Topics: Animals; Carbachol; Colitis; Colon; Diamines; Disease Models, Animal; Inflammation; Isometric Contra | 2011 |
Modulation of peripheral inflammatory pain thresholds by M(1) and nicotinic receptor antagonists.
Topics: Acetylcholine; Animals; Carrageenan; Dinoprostone; Hyperalgesia; Inflammation; Male; Mecamylamine; N | 2011 |
The anti-inflammatory effect of peripheral bee venom stimulation is mediated by central muscarinic type 2 receptors and activation of sympathetic preganglionic neurons.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Atropine; Autonomic Fibers, Preganglionic; Bee | 2005 |
Central muscarinic receptor subtypes and carrageenin-induced paw oedema in rats.
Topics: Animals; Arecoline; Carbachol; Carrageenan; Cerebellum; Corpus Striatum; Edema; Female; Foot; Gallam | 1991 |