pirenzepine has been researched along with Inadequate Sleep in 3 studies
Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of both REM sleep deprivation and its recovery on pontine and hippocampus muscarinic M2 receptors were investigated in synaptosomes using [3H]-AF-DX 384 as a ligand." | 1.30 | Decrease in muscarinic M2 receptors from synaptosomes in the pons and hippocampus after REM sleep deprivation in rats. ( Blanco-Centurión, C; Díaz-Muñoz, M; Ortiz-López, L; Rivera-Valerdi, L; Salín-Pascual, RJ, 1998) |
| "After 96 h of paradoxical sleep deprivation, [3H]AF-DX 384 binding was generally reduced throughout the brain, and significantly so in the olfactory tubercle (-20%), n." | 1.29 | Decreased muscarinic receptor binding in rat brain after paradoxical sleep deprivation: an autoradiographic study. ( Nobrega, JN; Nunes Júnior, GP; Tufik, S, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moreira, KM | 1 |
| Hipólide, DC | 1 |
| Nobrega, JN | 2 |
| Bueno, OF | 1 |
| Tufik, S | 2 |
| Oliveira, MG | 1 |
| Nunes Júnior, GP | 1 |
| Salín-Pascual, RJ | 1 |
| Díaz-Muñoz, M | 1 |
| Rivera-Valerdi, L | 1 |
| Ortiz-López, L | 1 |
| Blanco-Centurión, C | 1 |
3 other studies available for pirenzepine and Inadequate Sleep
| Article | Year |
|---|---|
Deficits in avoidance responding after paradoxical sleep deprivation are not associated with altered [3H]pirenzepine binding to M1 muscarinic receptors in rat brain.
Topics: Analysis of Variance; Animals; Autoradiography; Avoidance Learning; Behavior, Animal; Binding Sites; | 2003 |
Decreased muscarinic receptor binding in rat brain after paradoxical sleep deprivation: an autoradiographic study.
Topics: Animals; Autoradiography; Brain; Male; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Sleep | 1994 |
Decrease in muscarinic M2 receptors from synaptosomes in the pons and hippocampus after REM sleep deprivation in rats.
Topics: Animals; Hippocampus; Male; Parasympatholytics; Pirenzepine; Pons; Rats; Rats, Wistar; Receptor, Mus | 1998 |