Page last updated: 2024-11-02

pirenzepine and Hypotension

pirenzepine has been researched along with Hypotension in 5 studies

Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.

Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.

Research Excerpts

ExcerptRelevanceReference
"Olanzapine is an atypical antipsychotic medication indicated for the treatment of schizophrenia and other manifestations of psychotic illness."5.31Hypotension and bradycardia in a healthy volunteer following a single 5 mg dose of olanzapine. ( Boulton, DW; DeVane, CL; Liston, HL; Markowitz, JS; Risch, SC, 2002)
"The experiments employing high-frequency ultrasonic technique and selective blockers of M1, M3, and M4 muscarinic cholinergic receptors pirenzepine, 4-DAMP, and tropicamide, respectively, revealed individual roles of these receptors in the development of severe posthemorrhagic hypotension in rats with low or high individual resistance to circulatory hypoxia."3.78Role of various subtypes of muscarinic cholinergic receptors in the development of posthemorrhagic abnormalities in systemic and portal circulation in rats. ( Kovalenko, NY; Matsievskii, DD; Reshetnyak, VK, 2012)
"Olanzapine is an atypical antipsychotic medication indicated for the treatment of schizophrenia and other manifestations of psychotic illness."1.31Hypotension and bradycardia in a healthy volunteer following a single 5 mg dose of olanzapine. ( Boulton, DW; DeVane, CL; Liston, HL; Markowitz, JS; Risch, SC, 2002)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Menegatti, R1
Carvalho, FS1
Lião, LM1
Villavicencio, B1
Verli, H1
Mourão, AA1
Xavier, CH1
Castro, CH1
Pedrino, GR1
Franco, OL1
Oliveira-Silva, I1
Ashpole, NM1
Silva, ON1
Costa, EA1
Fajemiroye, JO1
Kovalenko, NY1
Matsievskii, DD1
Reshetnyak, VK1
Hata, T1
Itoh, E1
Funakami, Y1
Ishida, K1
Uchida, S1
Markowitz, JS1
DeVane, CL1
Boulton, DW1
Liston, HL1
Risch, SC1
Onat, FY1
Yegen, BC1
Lawrence, R1
Oktay, A1
Oktay, S1

Other Studies

5 other studies available for pirenzepine and Hypotension

ArticleYear
Novel choline analog 2-(4-((1-phenyl-1H-pyrazol-4-yl)methyl)piperazin-1-yl)ethan-1-ol produces sympathoinhibition, hypotension, and antihypertensive effects.
    Naunyn-Schmiedeberg's archives of pharmacology, 2019, Volume: 392, Issue:9

    Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Atropine; Blood Pressure; Heart Rate; Hypertensio

2019
Role of various subtypes of muscarinic cholinergic receptors in the development of posthemorrhagic abnormalities in systemic and portal circulation in rats.
    Bulletin of experimental biology and medicine, 2012, Volume: 152, Issue:3

    Topics: Animals; Blood Circulation; Blood Pressure; Hemorrhage; Hypotension; Male; Muscarinic Antagonists; P

2012
Blood pressure and heart rate are increased by AF-DX 116, a selective M2 antagonist, in autonomic imbalanced and hypotensive rats caused by repeated cold stress.
    Japanese journal of pharmacology, 2001, Volume: 85, Issue:3

    Topics: Animals; Atropine; Blood Pressure; Cold Temperature; Heart Rate; Hypotension; Male; Muscarinic Antag

2001
Hypotension and bradycardia in a healthy volunteer following a single 5 mg dose of olanzapine.
    Journal of clinical pharmacology, 2002, Volume: 42, Issue:1

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Blood Pressure; Bradycardia; Double-Blind Method; Fema

2002
Mad honey poisoning in man and rat.
    Reviews on environmental health, 1991, Volume: 9, Issue:1

    Topics: Aged; Animals; Atropine; Bradycardia; Diterpenes; Female; Honey; Humans; Hypotension; Male; Middle A

1991