pirenzepine has been researched along with Huntington Disease in 11 studies
Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.
Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
Excerpt | Relevance | Reference |
---|---|---|
"The aim was to describe the short-term (6 months) effects of olanzapine on behavioral and motor clinical manifestations in a group of 11 patients with Huntington disease." | 7.71 | Short-term effects of olanzapine in Huntington disease. ( Brusa, L; Cannella, M; Porcellini, A; Ruggieri, S; Simonelli, M; Squitieri, F, 2001) |
"The aim was to describe the short-term (6 months) effects of olanzapine on behavioral and motor clinical manifestations in a group of 11 patients with Huntington disease." | 3.71 | Short-term effects of olanzapine in Huntington disease. ( Brusa, L; Cannella, M; Porcellini, A; Ruggieri, S; Simonelli, M; Squitieri, F, 2001) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (18.18) | 18.2507 |
2000's | 9 (81.82) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Benazzi, F | 1 |
Bonelli, RM | 4 |
Dipple, HC | 1 |
Etchebehere, EC | 1 |
Lima, MC | 1 |
Passos, W | 1 |
Maciel Júnior, JA | 1 |
Santos, AO | 1 |
Ramos, CD | 1 |
Camargo, EE | 1 |
Grove, VE | 1 |
Quintanilla, J | 1 |
DeVaney, GT | 1 |
Squitieri, F | 1 |
Cannella, M | 1 |
Porcellini, A | 1 |
Brusa, L | 1 |
Simonelli, M | 1 |
Ruggieri, S | 1 |
Bogelman, G | 1 |
Hirschmann, S | 1 |
Modai, I | 1 |
Niederwieser, G | 3 |
Diez, J | 1 |
Költringer, P | 2 |
Tribl, GG | 1 |
Paleacu, D | 1 |
Anca, M | 1 |
Giladi, N | 1 |
2 trials available for pirenzepine and Huntington Disease
Article | Year |
---|---|
High-dose olanzapine in Huntington's disease.
Topics: Activities of Daily Living; Adult; Antipsychotic Agents; Benzodiazepines; Eye Movements; Female; Gai | 2002 |
Olanzapine in Huntington's disease.
Topics: Adult; Aged; Antipsychotic Agents; Benzodiazepines; Female; Humans; Huntington Disease; Male; Middle | 2002 |
9 other studies available for pirenzepine and Huntington Disease
Article | Year |
---|---|
Rapid onset of tardive dyskinesia in Huntington disease with olanzapine.
Topics: Antipsychotic Agents; Benzodiazepines; Dyskinesia, Drug-Induced; Humans; Huntington Disease; Male; M | 2002 |
Olanzapine-associated seizure.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Female; Humans; Huntington Disease; Olanzapine; Pirenz | 2003 |
The use of olanzapine for movement disorder in Huntington's disease: a first case report.
Topics: Antipsychotic Agents; Benzodiazepines; Humans; Huntington Disease; Male; Middle Aged; Olanzapine; Pi | 1999 |
Brain SPECT imaging in Huntington's disease before and after therapy with olanzapine. Case report.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Brain; Female; Humans; Huntington Disease; Olanzapine; | 1999 |
Improvement of Huntington's disease with olanzapine and valproate.
Topics: Adult; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Drug Therapy, Combination; Female; H | 2000 |
Short-term effects of olanzapine in Huntington disease.
Topics: Administration, Oral; Adult; Aged; Antipsychotic Agents; Anxiety; Benzodiazepines; Depression; Femal | 2001 |
Olanzapine and Huntington's disease.
Topics: Activities of Daily Living; Antipsychotic Agents; Benzodiazepines; Humans; Huntington Disease; Male; | 2001 |
Riluzole and olanzapine in Huntington's disease.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Female; Humans; Huntington Disease; Male; Neuroprotect | 2002 |
Apraxia of eyelid closure in Huntington's disease.
Topics: Apraxias; Benzodiazepines; Drug Therapy, Combination; Eyelid Diseases; Female; Humans; Huntington Di | 2002 |