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pirenzepine and Gastrointestinal Hemorrhage

pirenzepine has been researched along with Gastrointestinal Hemorrhage in 13 studies

Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.

Gastrointestinal Hemorrhage: Bleeding in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM.

Research Excerpts

ExcerptRelevanceReference
"We retrospectively investigated the efficacy of high dose omeprazole compared to a combined therapy of famotidine, pirenzepine and antacid for acute upper gastrointestinal hemorrhage (AUGIH) also adjuvant to endoscopic injection therapy if indicated."7.69[High-dose omeprazole versus famotidine, pirenzepine and antacid in therapy of acute upper gastrointestinal hemorrhage in a retrospective comparison]. ( Busam, J; Garbe, WE, 1994)
"We retrospectively investigated the efficacy of high dose omeprazole compared to a combined therapy of famotidine, pirenzepine and antacid for acute upper gastrointestinal hemorrhage (AUGIH) also adjuvant to endoscopic injection therapy if indicated."3.69[High-dose omeprazole versus famotidine, pirenzepine and antacid in therapy of acute upper gastrointestinal hemorrhage in a retrospective comparison]. ( Busam, J; Garbe, WE, 1994)
" These drugs can also induce toxic effects in the liver."2.38Side effects of stress bleeding prophylaxis. ( Tryba, M, 1989)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-199011 (84.62)18.7374
1990's2 (15.38)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bormioli, M1
Marconcini, M1
Teich-Alasia, S1
Valentini, P3
Tryba, M6
Huchzermeyer, H1
Török, M2
Zenz, M2
Pahlow, J1
Mazzarella, B1
Mastronardi, P1
Lettieri, B1
Lo Schiavo, F1
Chirletti, P1
Colobraro, P1
Romano, R1
Barzi, A1
Mangialardi, N1
Bertoldi, I1
Cirenei, A1
Busam, J1
Garbe, WE1
Nakajima, S1
Bamba, T1
Zevounou, F2
Wruck, G1
Stadler, H1
Giebler, A1
Tscheliessnigg, KH1
Berger, A1
Mischinger, HJ1
Engelhardt, D1
Karl, R1
Kolb, HJ1
Inthorn, D1
König, N1
Büll, U1
Hölzel, D1

Reviews

2 reviews available for pirenzepine and Gastrointestinal Hemorrhage

ArticleYear
[Recent progress in the drug therapy for gastrointestinal bleeding].
    Nihon rinsho. Japanese journal of clinical medicine, 1998, Volume: 56, Issue:9

    Topics: Anti-Ulcer Agents; Cimetidine; Gastric Acidity Determination; Gastrointestinal Hemorrhage; Histamine

1998
Side effects of stress bleeding prophylaxis.
    The American journal of medicine, 1989, Jun-09, Volume: 86, Issue:6A

    Topics: Bacteria; Gastric Juice; Gastrointestinal Hemorrhage; Histamine H2 Antagonists; Humans; Hydrogen-Ion

1989

Trials

5 trials available for pirenzepine and Gastrointestinal Hemorrhage

ArticleYear
Prevention of stress bleeding with ranitidine or pirenzepine and the risk of pneumonia.
    Journal of clinical anesthesia, 1988, Volume: 1, Issue:1

    Topics: Adult; Aged; Bacterial Infections; Female; Gastric Juice; Gastrointestinal Hemorrhage; Gram-Negative

1988
[Stress bleeding and postoperative pneumonias in intensive care patients on ranitidine or pirenzepine].
    Deutsche medizinische Wochenschrift (1946), 1988, Jun-10, Volume: 113, Issue:23

    Topics: Clinical Trials as Topic; Critical Care; Female; Gastric Acidity Determination; Gastrointestinal Hem

1988
Prevention of acute stress bleeding with sucralfate, antacids, or cimetidine. A controlled study with pirenzepine as a basic medication.
    The American journal of medicine, 1985, Aug-30, Volume: 79, Issue:2C

    Topics: Adult; Aged; Aluminum; Antacids; Anti-Ulcer Agents; Benzodiazepinones; Cimetidine; Critical Care; Dr

1985
[Conservative therapy of upper gastrointestinal hemorrhage (prospective, randomized, controlled)].
    Wiener medizinische Wochenschrift (1946), 1985, Nov-15, Volume: 135, Issue:21

    Topics: Aluminum; Benzodiazepinones; Calcium; Cimetidine; Drug Therapy, Combination; Estrogens; Gastrointest

1985
[Comparison between cimetidine-pirenzepine and antacids for the prevention of stress hemorrhage in intensive care patients. A controlled clinical study on 125 patients].
    Deutsche medizinische Wochenschrift (1946), 1985, Jun-07, Volume: 110, Issue:23

    Topics: Adult; Aged; Antacids; Benzodiazepinones; Chromium Radioisotopes; Cimetidine; Clinical Trials as Top

1985

Other Studies

6 other studies available for pirenzepine and Gastrointestinal Hemorrhage

ArticleYear
[Upper digestive hemorrhages in burns. Prevention with pirenzepin].
    Minerva chirurgica, 1983, Apr-15, Volume: 38, Issue:7

    Topics: Adolescent; Adult; Anti-Ulcer Agents; Benzodiazepinones; Burns; Child; Child, Preschool; Female; Gas

1983
Single-drug and combined medication with cimetidine, antacids and pirenzepine in the prophylaxis of acute upper gastrointestinal bleeding.
    Hepato-gastroenterology, 1983, Volume: 30, Issue:4

    Topics: Acute Disease; Antacids; Benzodiazepinones; Cimetidine; Drug Therapy, Combination; Gastrointestinal

1983
[Prevention and treatment of gastro-duodenal hemorrhagic complications in patients with neurologic lesions].
    La Clinica terapeutica, 1983, Sep-15, Volume: 106, Issue:5

    Topics: Adolescent; Adult; Aged; Benzodiazepinones; Brain Injuries; Cerebrovascular Disorders; Female; Gastr

1983
[Pirenzepine parenterally administered in high doses in the treatment of upper digestive hemorrhage].
    Minerva medica, 1984, Jan-14, Volume: 75, Issue:1-2

    Topics: Adult; Aged; Benzodiazepinones; Duodenitis; Female; Gastritis; Gastrointestinal Hemorrhage; Humans;

1984
[High-dose omeprazole versus famotidine, pirenzepine and antacid in therapy of acute upper gastrointestinal hemorrhage in a retrospective comparison].
    Zeitschrift fur Gastroenterologie, 1994, Volume: 32, Issue:2

    Topics: Aged; Aged, 80 and over; Aluminum Hydroxide; Antacids; Dose-Response Relationship, Drug; Drug Admini

1994
[Prevention of stress bleeding--do we need a new concept?].
    Deutsche medizinische Wochenschrift (1946), 1986, Oct-24, Volume: 111, Issue:43

    Topics: Antacids; Cimetidine; Gastrointestinal Hemorrhage; Histamine H2 Antagonists; Humans; Pirenzepine; St

1986