pirenzepine has been researched along with Gastrointestinal Hemorrhage in 13 studies
Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.
Gastrointestinal Hemorrhage: Bleeding in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We retrospectively investigated the efficacy of high dose omeprazole compared to a combined therapy of famotidine, pirenzepine and antacid for acute upper gastrointestinal hemorrhage (AUGIH) also adjuvant to endoscopic injection therapy if indicated." | 7.69 | [High-dose omeprazole versus famotidine, pirenzepine and antacid in therapy of acute upper gastrointestinal hemorrhage in a retrospective comparison]. ( Busam, J; Garbe, WE, 1994) |
| "We retrospectively investigated the efficacy of high dose omeprazole compared to a combined therapy of famotidine, pirenzepine and antacid for acute upper gastrointestinal hemorrhage (AUGIH) also adjuvant to endoscopic injection therapy if indicated." | 3.69 | [High-dose omeprazole versus famotidine, pirenzepine and antacid in therapy of acute upper gastrointestinal hemorrhage in a retrospective comparison]. ( Busam, J; Garbe, WE, 1994) |
| " These drugs can also induce toxic effects in the liver." | 2.38 | Side effects of stress bleeding prophylaxis. ( Tryba, M, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (84.62) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bormioli, M | 1 |
| Marconcini, M | 1 |
| Teich-Alasia, S | 1 |
| Valentini, P | 3 |
| Tryba, M | 6 |
| Huchzermeyer, H | 1 |
| Török, M | 2 |
| Zenz, M | 2 |
| Pahlow, J | 1 |
| Mazzarella, B | 1 |
| Mastronardi, P | 1 |
| Lettieri, B | 1 |
| Lo Schiavo, F | 1 |
| Chirletti, P | 1 |
| Colobraro, P | 1 |
| Romano, R | 1 |
| Barzi, A | 1 |
| Mangialardi, N | 1 |
| Bertoldi, I | 1 |
| Cirenei, A | 1 |
| Busam, J | 1 |
| Garbe, WE | 1 |
| Nakajima, S | 1 |
| Bamba, T | 1 |
| Zevounou, F | 2 |
| Wruck, G | 1 |
| Stadler, H | 1 |
| Giebler, A | 1 |
| Tscheliessnigg, KH | 1 |
| Berger, A | 1 |
| Mischinger, HJ | 1 |
| Engelhardt, D | 1 |
| Karl, R | 1 |
| Kolb, HJ | 1 |
| Inthorn, D | 1 |
| König, N | 1 |
| Büll, U | 1 |
| Hölzel, D | 1 |
2 reviews available for pirenzepine and Gastrointestinal Hemorrhage
| Article | Year |
|---|---|
[Recent progress in the drug therapy for gastrointestinal bleeding].
Topics: Anti-Ulcer Agents; Cimetidine; Gastric Acidity Determination; Gastrointestinal Hemorrhage; Histamine | 1998 |
Side effects of stress bleeding prophylaxis.
Topics: Bacteria; Gastric Juice; Gastrointestinal Hemorrhage; Histamine H2 Antagonists; Humans; Hydrogen-Ion | 1989 |
5 trials available for pirenzepine and Gastrointestinal Hemorrhage
| Article | Year |
|---|---|
Prevention of stress bleeding with ranitidine or pirenzepine and the risk of pneumonia.
Topics: Adult; Aged; Bacterial Infections; Female; Gastric Juice; Gastrointestinal Hemorrhage; Gram-Negative | 1988 |
[Stress bleeding and postoperative pneumonias in intensive care patients on ranitidine or pirenzepine].
Topics: Clinical Trials as Topic; Critical Care; Female; Gastric Acidity Determination; Gastrointestinal Hem | 1988 |
Prevention of acute stress bleeding with sucralfate, antacids, or cimetidine. A controlled study with pirenzepine as a basic medication.
Topics: Adult; Aged; Aluminum; Antacids; Anti-Ulcer Agents; Benzodiazepinones; Cimetidine; Critical Care; Dr | 1985 |
[Conservative therapy of upper gastrointestinal hemorrhage (prospective, randomized, controlled)].
Topics: Aluminum; Benzodiazepinones; Calcium; Cimetidine; Drug Therapy, Combination; Estrogens; Gastrointest | 1985 |
[Comparison between cimetidine-pirenzepine and antacids for the prevention of stress hemorrhage in intensive care patients. A controlled clinical study on 125 patients].
Topics: Adult; Aged; Antacids; Benzodiazepinones; Chromium Radioisotopes; Cimetidine; Clinical Trials as Top | 1985 |
6 other studies available for pirenzepine and Gastrointestinal Hemorrhage
| Article | Year |
|---|---|
[Upper digestive hemorrhages in burns. Prevention with pirenzepin].
Topics: Adolescent; Adult; Anti-Ulcer Agents; Benzodiazepinones; Burns; Child; Child, Preschool; Female; Gas | 1983 |
Single-drug and combined medication with cimetidine, antacids and pirenzepine in the prophylaxis of acute upper gastrointestinal bleeding.
Topics: Acute Disease; Antacids; Benzodiazepinones; Cimetidine; Drug Therapy, Combination; Gastrointestinal | 1983 |
[Prevention and treatment of gastro-duodenal hemorrhagic complications in patients with neurologic lesions].
Topics: Adolescent; Adult; Aged; Benzodiazepinones; Brain Injuries; Cerebrovascular Disorders; Female; Gastr | 1983 |
[Pirenzepine parenterally administered in high doses in the treatment of upper digestive hemorrhage].
Topics: Adult; Aged; Benzodiazepinones; Duodenitis; Female; Gastritis; Gastrointestinal Hemorrhage; Humans; | 1984 |
[High-dose omeprazole versus famotidine, pirenzepine and antacid in therapy of acute upper gastrointestinal hemorrhage in a retrospective comparison].
Topics: Aged; Aged, 80 and over; Aluminum Hydroxide; Antacids; Dose-Response Relationship, Drug; Drug Admini | 1994 |
[Prevention of stress bleeding--do we need a new concept?].
Topics: Antacids; Cimetidine; Gastrointestinal Hemorrhage; Histamine H2 Antagonists; Humans; Pirenzepine; St | 1986 |