pirenzepine has been researched along with Gastroduodenal Ulcer in 80 studies
Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The main pharmacodynamic characteristics of pirenzepine are briefly reported and the experimental plan of the clinical trial on pirenzepine in peptic ulcer is discussed." | 9.04 | Pirenzepine in peptic ulcer. Introduction to clinical trials reports. ( Chierichetti, SM; Gaetani, M; Petrin, G, 1979) |
| "Toxic hepatitis developed but in one out of 127 peptic ulcer patients treated with cimetidine." | 7.68 | [The effect of cimetidine and gastrozepin on liver function and the pharmacotherapy of "hepatogenous" gastroduodenal ulcers and erosions]. ( Bessonova, GA; Geller, LI; Griaznova, MV, 1991) |
| "Pirenzepine (Gastrozepin) is a drug recently introduced in the therapy of gastroduodenal ulcer (GDU)." | 7.66 | Inhibition of gastric mucosa carbonic anhydrase by pirenzepine in patients with gastroduodenal ulcers. ( Búzás, G; Domuta, M; Puşcaş, I; Surányi, P, 1981) |
| "Pirenzepine has been reported to inhibit gastrin secretion." | 6.68 | Effects of pirenzepine on omeprazole-induced hypergastrinemia and acid suppression in peptic ulcer patients. ( Fukino, Y; Hamada, M; Haruma, K; Inoue, M; Kajiyama, G; Kamiyasu, T; Sumii, K; Sumii, M; Tari, A, 1996) |
| "Pirenzepine is a 'selective' antimuscarinic agent which, unlike classic anticholinergic agents, inhibits gastric acid secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular and urinary functions." | 6.37 | Pirenzepine. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in peptic ulcer disease and other allied diseases. ( Brogden, RN; Carmine, AA, 1985) |
| "Pirenzepine appears to be an effective drug for the short-term treatment of duodenal ulcer." | 6.36 | Pirenzepine in the treatment of peptic ulcer disease. Review and commentary. ( Bianchi Porro, G; Petrillo, M, 1982) |
| "Serum gastrin levels in 44 peptic ulcer patients (26 gastric ulcer patients and 18 duodenal ulcer patients) were determined after they had been treated with omeprazole (OPZ) (20 mg/day) alone or in combination with pirenzepine (PZP) (100 mg/day)." | 5.07 | Serum gastrin levels following administration of omeprazole alone or in combination with pirenzepine. ( Arakawa, Y; Ito, K; Iwasaki, A; Kawamura, Y; Matsuo, Y; Miyazawa, K; Sakai, Y; Tashiro, Y, 1994) |
| "Four hundred and two patients with peptic ulcer were selected for acute therapy with either pirenzepine (100 mg/day) or cimetidine (800 mg/day) using the envelope method." | 5.07 | Predictors of relapse in peptic ulcer. ( Asaki, S; Inoue, S; Ishimori, A; Kano, A; Kawakami, K; Kawamura, T; Koizumi, F; Takahashi, T, 1992) |
| "In two studies the beneficial effect of Pirenzepine in the treatment of peptic duodenal and gastric ulcers was investigated in 1686 outpatients." | 5.05 | [Treatment of ulcers with pirenzepin. Results from clinic and practice]. ( Kalk, A; Krempler, F; Sandhofer, F, 1982) |
| "The main pharmacodynamic characteristics of pirenzepine are briefly reported and the experimental plan of the clinical trial on pirenzepine in peptic ulcer is discussed." | 5.04 | Pirenzepine in peptic ulcer. Introduction to clinical trials reports. ( Chierichetti, SM; Gaetani, M; Petrin, G, 1979) |
| "The healing rate of duodenal ulcers may be accelerated by secretory inhibitors such as histamine H2-receptor antagonists and pirenzepine, by antacids, by protective drugs such as sucralfate and colloidal bismuth, and by antidepressant drugs such as trimipramine." | 4.77 | Therapeutic approach to ulcer healing. ( Blum, AL, 1985) |
| "Toxic hepatitis developed but in one out of 127 peptic ulcer patients treated with cimetidine." | 3.68 | [The effect of cimetidine and gastrozepin on liver function and the pharmacotherapy of "hepatogenous" gastroduodenal ulcers and erosions]. ( Bessonova, GA; Geller, LI; Griaznova, MV, 1991) |
| "Both H2-receptor antagonists and pirenzepine are used in the treatment of peptic ulcer disease." | 3.68 | Combined effect of pirenzepine and ranitidine on the nocturnal intragastric pH in non-responders to ranitidine. ( Bode, JC; Klotz, U; Walker, S, 1990) |
| "Pirenzepine (Gastrozepin) is a drug recently introduced in the therapy of gastroduodenal ulcer (GDU)." | 3.66 | Inhibition of gastric mucosa carbonic anhydrase by pirenzepine in patients with gastroduodenal ulcers. ( Búzás, G; Domuta, M; Puşcaş, I; Surányi, P, 1981) |
| "Pirenzepine has been reported to inhibit gastrin secretion." | 2.68 | Effects of pirenzepine on omeprazole-induced hypergastrinemia and acid suppression in peptic ulcer patients. ( Fukino, Y; Hamada, M; Haruma, K; Inoue, M; Kajiyama, G; Kamiyasu, T; Sumii, K; Sumii, M; Tari, A, 1996) |
| " A side effect encountered was sinus tachycardia in 4 of 27 patients treated with pirenzepine." | 2.66 | [Prevention of gastroduodenal stress lesions with secretion inhibitors in accident patients needing intensive care: incidence of lesions and adverse effects; consequences]. ( Barandun, J; Frutiger, A; Kobler, E; Leutenegger, A; Rüedi, T, 1985) |
| " Inhibition of acid secretion by secretin was dose-dependent; the dosage clinically applied so far (10 CU/kg s." | 2.65 | [Effectiveness of cimetidine, pirenzepine and synthetic secretin on stimulated gastric acid secretion]. ( Londong, V; Londong, W; Prechtl, R; Schwanner, A, 1980) |
| "Famotidine is an even more potent H2 receptor antagonist, and initial clinical studies are promising." | 2.37 | Pharmacological management of patients with peptic ulcer disease: prospects for the late 1980's. ( Mahachai, V; Thomson, AB, 1987) |
| "Pirenzepine is a 'selective' antimuscarinic agent which, unlike classic anticholinergic agents, inhibits gastric acid secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular and urinary functions." | 2.37 | Pirenzepine. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in peptic ulcer disease and other allied diseases. ( Brogden, RN; Carmine, AA, 1985) |
| "Pirenzepine appears to be an effective drug for the short-term treatment of duodenal ulcer." | 2.36 | Pirenzepine in the treatment of peptic ulcer disease. Review and commentary. ( Bianchi Porro, G; Petrillo, M, 1982) |
| ""Vagal" peptic ulcers were found by the gastrocepin test." | 1.28 | [The digestive activity of the chymus in the gastric stump in postgastrectomy peptic ulcers]. ( Fil'kov, AP; Podoluzhnyĭ, VI, 1992) |
| "Pirenzepine (10 mg) was given via the peripheral or central venous route at an injection velocity of 5 or 30 seconds as well as a control of 2 ml normal saline solution via the central venous route for 5 seconds, 20 times each." | 1.28 | [Cardiac adverse effects following an intravenous injection of pirenzepine are an expression of deficient receptor sensitivity]. ( Klein, G; Lischke, V; Probst, S; Wiederspahn, T, 1991) |
| "It has long been known that gastroduodenal ulcers may heal spontaneously; this is the placebo effect in which the healing rate ranges from 20% at 2 weeks to 80% at 8 weeks." | 1.27 | [Innovations in the treatment of gastroduodenal ulcers]. ( Bernier, JJ, 1983) |
| "The possible pharmacokinetic interactions between pirenzepin and theophylline were investigated in an open single blind trial." | 1.27 | Pirenzepin does not alter the pharmacokinetics of theophylline. ( Meryn, S; Rameis, H; Sertl, K, 1987) |
| "There have been recent findings of gastric cancer in patients treated with cimetidine but too soon after treatment for that drug to have had a pathogenetic role." | 1.27 | The risk of gastric dysplasia in medical long-term treatment of peptic ulcer disease. ( Cardin, F; Di Mario, F; Farinati, F, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 63 (78.75) | 18.7374 |
| 1990's | 15 (18.75) | 18.2507 |
| 2000's | 2 (2.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gubergrits, NB | 1 |
| Gostishchev, VK | 1 |
| Evseev, MA | 1 |
| Clémençon, GH | 1 |
| Holtermüller, KH | 1 |
| Lagarde, SP | 1 |
| Spiro, HM | 1 |
| Barandun, J | 2 |
| Leutenegger, A | 2 |
| Frutiger, A | 2 |
| Rüedi, T | 2 |
| Kobler, E | 2 |
| Honorato Pérez, J | 1 |
| Azanza Perea, JR | 1 |
| Cuena Boy, R | 1 |
| Melloni, R | 1 |
| Melloni, GF | 1 |
| Scarazatti, E | 1 |
| Bernier, JJ | 1 |
| Piper, DW | 1 |
| Feldman, M | 1 |
| Kishimoto, S | 1 |
| Kajiyama, G | 2 |
| Miyoshi, A | 1 |
| Ryss, ES | 2 |
| Dammann, HG | 1 |
| Walter, TA | 1 |
| Müller, P | 1 |
| Simon, B | 1 |
| Grigor'ev, PIa | 2 |
| Khar'kovskiĭ, NN | 1 |
| Elina, NA | 1 |
| El'tsova, NB | 1 |
| Elisova, NV | 1 |
| Saeki, S | 1 |
| Tomofuji, Y | 1 |
| Yasuda, T | 1 |
| Mitooka, H | 1 |
| Onoyama, Y | 1 |
| Baba, S | 1 |
| Pavlotzky, M | 1 |
| Eshchar, J | 1 |
| Zelenková, J | 1 |
| Toman, R | 1 |
| Levinson, RA | 1 |
| Weberg, R | 1 |
| Narverud, G | 1 |
| Berstad, A | 1 |
| Krempler, F | 2 |
| Sandhofer, F | 2 |
| Kalk, A | 2 |
| Bianchi Porro, G | 1 |
| Petrillo, M | 1 |
| Bayeli, PF | 1 |
| Benelli, R | 1 |
| Hammer, R | 1 |
| Koss, FW | 1 |
| Londong, W | 3 |
| Londong, V | 1 |
| Prechtl, R | 1 |
| Schwanner, A | 1 |
| Mattes, P | 1 |
| Peros, G | 1 |
| Belohlavek, D | 1 |
| Malfertheiner, P | 1 |
| Herfarth, C | 1 |
| Neumayr, A | 1 |
| Weiss, W | 1 |
| Puşcaş, I | 1 |
| Búzás, G | 1 |
| Surányi, P | 1 |
| Domuta, M | 1 |
| Dotevall, G | 1 |
| Jaup, BH | 2 |
| Stockbrügger, RW | 1 |
| Bertoglio, S | 1 |
| Anfossi, A | 1 |
| Arnulfo, G | 1 |
| Valentini, P | 3 |
| Berti Riboli, E | 1 |
| Brunner, H | 1 |
| Ishimori, A | 5 |
| Iwasaki, A | 1 |
| Miyazawa, K | 1 |
| Kawamura, Y | 1 |
| Sakai, Y | 1 |
| Tashiro, Y | 1 |
| Ito, K | 1 |
| Arakawa, Y | 1 |
| Matsuo, Y | 1 |
| Kalinin, AV | 1 |
| Loginov, AF | 1 |
| Antokhin, EA | 1 |
| Tari, A | 1 |
| Hamada, M | 1 |
| Kamiyasu, T | 1 |
| Fukino, Y | 1 |
| Sumii, M | 1 |
| Haruma, K | 1 |
| Sumii, K | 1 |
| Inoue, M | 1 |
| Zaĭtseva, EI | 1 |
| Titova, OV | 1 |
| Melekhova, LS | 1 |
| Makarenko, TG | 1 |
| Sosina, TE | 1 |
| Chierichetti, SM | 1 |
| Gaetani, M | 1 |
| Petrin, G | 1 |
| Podoluzhnyĭ, VI | 1 |
| Fil'kov, AP | 1 |
| Kawamura, T | 3 |
| Koizumi, F | 3 |
| Kawakami, K | 1 |
| Inoue, S | 1 |
| Kano, A | 1 |
| Takahashi, T | 1 |
| Asaki, S | 1 |
| Walker, S | 2 |
| Sarem-Aslani, A | 1 |
| Treiber, G | 1 |
| Klotz, U | 2 |
| Bode, JC | 2 |
| Geller, LI | 1 |
| Bessonova, GA | 1 |
| Griaznova, MV | 1 |
| Probst, S | 1 |
| Lischke, V | 1 |
| Wiederspahn, T | 1 |
| Klein, G | 1 |
| Janisch, HD | 1 |
| Fujimoto, H | 1 |
| De Natale, G | 1 |
| De Natale, F | 1 |
| Marino, A | 1 |
| Debas, HT | 1 |
| Mulholland, MW | 1 |
| Sorf, M | 1 |
| Krislo, V | 1 |
| Jablonský, I | 1 |
| Stockbruegger, RW | 1 |
| Blum, AL | 1 |
| Guslandi, M | 1 |
| Howden, CW | 1 |
| Burget, DW | 1 |
| Silletti, C | 1 |
| Hunt, RH | 1 |
| Thomson, AB | 1 |
| Mahachai, V | 1 |
| Ishikawa, M | 1 |
| Saito, H | 1 |
| Sato, J | 1 |
| Isakov, VA | 1 |
| Vasil'eva, ZI | 1 |
| Kuhn, E | 2 |
| Lodin, Z | 1 |
| Lovacký, S | 2 |
| Tauber, O | 2 |
| Zizkovský, V | 1 |
| Dvorák, P | 1 |
| Srajer, S | 1 |
| Skála, I | 1 |
| Kapitanenko, AM | 2 |
| Karnaukhov, IuN | 2 |
| Edge, DP | 1 |
| Brown, P | 1 |
| Luey, K | 1 |
| Stace, NH | 1 |
| Yachi, A | 1 |
| Yabana, T | 1 |
| Takai, Y | 1 |
| Shastin, IV | 1 |
| Merkur'ev, ND | 1 |
| Smirnov, PA | 1 |
| Butti, A | 1 |
| De Giovanni, L | 1 |
| Reggio, D | 1 |
| Civello, IM | 1 |
| Andĕl, M | 1 |
| Brodan, V | 1 |
| Veselková, A | 1 |
| Sertl, K | 1 |
| Rameis, H | 1 |
| Meryn, S | 1 |
| Lederer, PC | 1 |
| Lux, G | 1 |
| Testasecca, D | 1 |
| Sestili, R | 1 |
| Pennacchioni, S | 1 |
| Ventrella, S | 1 |
| Torroni, P | 1 |
| Tjia, AT | 1 |
| Legeza, G | 1 |
| More, DG | 1 |
| Raper, RF | 1 |
| Watson, CJ | 1 |
| Shenfield, GM | 1 |
| Fisher, AA | 1 |
| Borisov, IuIu | 1 |
| Di Mario, F | 1 |
| Farinati, F | 1 |
| Cardin, F | 1 |
| Stadler, H | 1 |
| Giebler, A | 1 |
| Tscheliessnigg, KH | 1 |
| Berger, A | 1 |
| Mischinger, HJ | 1 |
| Carmine, AA | 1 |
| Brogden, RN | 1 |
15 reviews available for pirenzepine and Gastroduodenal Ulcer
| Article | Year |
|---|---|
[Conservative therapy of peptic ulcer].
Topics: Antacids; Benzodiazepinones; Carbenoxolone; Cimetidine; Gastric Acid; Gastroscopy; Histamine H2 Anta | 1980 |
Non-ulcer dyspepsia.
Topics: Antacids; Benzodiazepinones; Diet; Duodenitis; Dyspepsia; Gastric Acid; Gastritis; Gastrointestinal | 1984 |
Drugs for the prevention of peptic ulcer recurrence.
Topics: Aluminum; Anti-Ulcer Agents; Benzodiazepinones; Cimetidine; Humans; Parasympatholytics; Peptic Ulcer | 1983 |
Inhibition of gastric acid secretion by selective and nonselective anticholinergics.
Topics: Benzodiazepinones; Gastric Acid; Humans; Neuromuscular Blocking Agents; Parasympathetic Nervous Syst | 1984 |
[Selective muscarinic receptor antagonists].
Topics: Anti-Ulcer Agents; Atropine; Benzodiazepinones; Gastric Acid; Humans; Peptic Ulcer; Pirenzepine; Rec | 1984 |
[Selective and locally-acting drugs in the treatment of peptic ulcer].
Topics: Acetazolamide; Aluminum; Anti-Ulcer Agents; Benzodiazepinones; Bismuth; Carbenoxolone; Cimetidine; E | 1984 |
Pirenzepine in the treatment of peptic ulcer disease. Review and commentary.
Topics: Anti-Ulcer Agents; Benzodiazepinones; Humans; Parasympatholytics; Peptic Ulcer; Pirenzepine; Recurre | 1982 |
[Drugs used in the therapy of peptic ulcer with special reference to H2 receptor blockaders].
Topics: Antacids; Anti-Ulcer Agents; Cimetidine; Famotidine; Female; Histamine H2 Antagonists; Humans; Male; | 1989 |
Drug therapy in peptic ulcer disease.
Topics: Cimetidine; Histamine Antagonists; Humans; Omeprazole; Peptic Ulcer; Pirenzepine; Prostaglandins; Ra | 1989 |
Therapeutic approach to ulcer healing.
Topics: Aluminum; Antacids; Anti-Ulcer Agents; Antidepressive Agents; Benzodiazepinones; Bismuth; Colloids; | 1985 |
Ulcer-healing drugs and endogenous prostaglandins.
Topics: Aluminum; Animals; Anti-Ulcer Agents; Benzimidazoles; Benzodiazepinones; Carbenoxolone; Cimetidine; | 1985 |
[Current locally acting agents in the treatment of peptic ulcer].
Topics: Antacids; Anti-Ulcer Agents; Antidepressive Agents, Tricyclic; Carbonic Anhydrase Inhibitors; Histam | 1986 |
Pharmacological management of patients with peptic ulcer disease: prospects for the late 1980's.
Topics: Alprostadil; Antacids; Anti-Ulcer Agents; Cimetidine; Drug Resistance; Enprostil; Famotidine; Histam | 1987 |
[Pathophysiologic bases of the pharmacotherapy of peptic ulcer].
Topics: Anti-Ulcer Agents; Histamine H2 Antagonists; Humans; Omeprazole; Organometallic Compounds; Peptic Ul | 1988 |
Pirenzepine. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in peptic ulcer disease and other allied diseases.
Topics: Benzodiazepinones; Dialysis; Dyspepsia; Gastric Acid; Gastrins; Gastrointestinal Hormones; Humans; I | 1985 |
22 trials available for pirenzepine and Gastroduodenal Ulcer
| Article | Year |
|---|---|
[What is safe in conservative ulcer therapy? An evaluation of results from clinical studies].
Topics: Aluminum; Antacids; Benzodiazepinones; Carbenoxolone; Clinical Trials as Topic; Feeding Behavior; Hi | 1982 |
[Incidence of gastro-duodenal stress lesions in trauma patients requiring intensive care, treated with secretory inhibitors. A double blind study].
Topics: Benzodiazepinones; Cimetidine; Clinical Trials as Topic; Critical Care; Double-Blind Method; Histami | 1984 |
[Behavior of blood values of prolactin, TSH, FSH, and LH in gastroduodenal ulcer during drug therapy].
Topics: Adult; Anti-Ulcer Agents; Benzodiazepinones; Carbenoxolone; Cimetidine; Clinical Trials as Topic; Fo | 1984 |
[Pirenzepine in gastric and duodenal ulcer: randomized comparison with cimetidine].
Topics: Adult; Aged; Anti-Ulcer Agents; Benzodiazepinones; Cimetidine; Clinical Trials as Topic; Female; Gua | 1982 |
[Treatment of ulcers with pirenzepin. Results from clinic and practice].
Topics: Adult; Anti-Ulcer Agents; Benzodiazepinones; Carbenoxolone; Chemical Phenomena; Chemistry; Cimetidin | 1982 |
[Effectiveness of cimetidine, pirenzepine and synthetic secretin on stimulated gastric acid secretion].
Topics: Adult; Anti-Ulcer Agents; Benzodiazepinones; Cimetidine; Drug Therapy, Combination; Gastric Acid; Ga | 1980 |
Pirenzepine and cimetidine in the treatment of peptic ulcer.
Topics: Anti-Ulcer Agents; Benzodiazepinones; Cimetidine; Drug Therapy, Combination; Female; Guanidines; Hum | 1982 |
Prevention of peptic ulcer relapse.
Topics: Cimetidine; Double-Blind Method; Humans; Life Tables; Peptic Ulcer; Pirenzepine; Proportional Hazard | 1994 |
Serum gastrin levels following administration of omeprazole alone or in combination with pirenzepine.
Topics: Drug Therapy, Combination; Duodenal Ulcer; Gastrins; Humans; Omeprazole; Peptic Ulcer; Pirenzepine; | 1994 |
Effects of pirenzepine on omeprazole-induced hypergastrinemia and acid suppression in peptic ulcer patients.
Topics: Adult; Aged; Anti-Ulcer Agents; Drug Therapy, Combination; Duodenal Ulcer; Female; Gastric Acid; Gas | 1996 |
Pirenzepine in peptic ulcer. Introduction to clinical trials reports.
Topics: Anti-Ulcer Agents; Atropine; Benzodiazepinones; Clinical Trials as Topic; Humans; Peptic Ulcer; Pipe | 1979 |
Effect of drug therapy on the relapse of peptic ulcers. 1st communication: the effect of acute therapy.
Topics: Cimetidine; Double-Blind Method; Humans; Peptic Ulcer; Pirenzepine; Recurrence; Stomach Ulcer | 1992 |
Effect of drug therapy on the relapse of peptic ulcers. 2nd communication: the effect of maintenance therapy.
Topics: Cimetidine; Double-Blind Method; Humans; Peptic Ulcer; Pirenzepine; Recurrence | 1992 |
Predictors of relapse in peptic ulcer.
Topics: Adult; Cimetidine; Double-Blind Method; Female; Humans; Male; Peptic Ulcer; Pirenzepine; Prognosis; | 1992 |
Bacterial overgrowth as a consequence of reduced gastric acidity.
Topics: Achlorhydria; Aged; Anemia, Pernicious; Bacteria; Benzodiazepinones; Cimetidine; Clinical Trials as | 1985 |
Single nocturnal doses of pirenzepine effectively inhibit overnight gastric secretion.
Topics: Adult; Benzodiazepinones; Gastric Acidity Determination; Gastric Mucosa; Histamine H2 Antagonists; H | 1985 |
Once-nightly treatment with pirenzepine or cimetidine for peptic ulcers: a multicentre, randomised, double blind, controlled study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cimetidine; Clinical Trials as Topic; Double-Blind Metho | 1987 |
[Use of gastrocepin in middle-aged and elderly patients with peptic ulcer].
Topics: Age Factors; Aged; Anti-Ulcer Agents; Benzodiazepinones; Clinical Trials as Topic; Female; Gastric A | 1986 |
[Use of pirenzepine in prevention of stress ulcers in high-risk surgical patients].
Topics: Adult; Aged; Anti-Ulcer Agents; Benzodiazepinones; Clinical Trials as Topic; Female; Humans; Infusio | 1986 |
[Prevention of gastroduodenal stress lesions with secretion inhibitors in accident patients needing intensive care: incidence of lesions and adverse effects; consequences].
Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Benzodiazepinones; Cimetidine; Critical Care; Double-Bli | 1985 |
[Conservative therapy of upper gastrointestinal hemorrhage (prospective, randomized, controlled)].
Topics: Aluminum; Benzodiazepinones; Calcium; Cimetidine; Drug Therapy, Combination; Estrogens; Gastrointest | 1985 |
Pirenzepine: a selective anticholinergic for peptic ulcer.
Topics: Anti-Ulcer Agents; Benzodiazepinones; Clinical Trials as Topic; Drug Therapy, Combination; Gastric A | 1985 |
43 other studies available for pirenzepine and Gastroduodenal Ulcer
| Article | Year |
|---|---|
[Gastrozepin: is its oblivion fair?].
Topics: Anti-Ulcer Agents; Humans; Peptic Ulcer; Pirenzepine | 2003 |
[Antisecretory therapy as a component of hemostasis in acute gastroduodenal ulcer bleedings].
Topics: Acute Disease; Anti-Ulcer Agents; Famotidine; Gastrointestinal Agents; Histamine H2 Antagonists; Hum | 2005 |
New drugs for peptic ulcer.
Topics: Benzamides; Benzodiazepinones; Cimetidine; Furans; Guanidines; Histamine H2 Antagonists; Humans; Mor | 1980 |
[Pharmacologic treatment of ulcers].
Topics: Aluminum; Antacids; Anti-Ulcer Agents; Benzodiazepinones; Carbenoxolone; Gastric Mucosa; Histamine H | 1984 |
[Innovations in the treatment of gastroduodenal ulcers].
Topics: Aluminum; Antacids; Anti-Ulcer Agents; Benzodiazepinones; Bismuth; Cimetidine; Furans; Humans; Organ | 1983 |
[Anti-ulcer agents. Clinico-experimental findings].
Topics: Antacids; Anti-Ulcer Agents; Benzimidazoles; Benzodiazepinones; Cimetidine; Histamine Antagonists; H | 1984 |
[Treatment of peptic ulcer with gastrozepin].
Topics: Adult; Aged; Anti-Ulcer Agents; Benzodiazepinones; Chronic Disease; Drug Evaluation; Female; Humans; | 1984 |
[Appraisal of therapeutic agents for peptic ulcer by continuous intragastric pH monitoring].
Topics: Adult; Aged; Anti-Ulcer Agents; Benzodiazepinones; Cimetidine; Gastric Acid; Gastric Acidity Determi | 1984 |
[Pirenzepin--a new drug in peptic diseases].
Topics: Anti-Ulcer Agents; Benzodiazepinones; Esophagitis, Peptic; Humans; Peptic Ulcer; Pirenzepine | 1983 |
[Treatment of gastroduodenal ulcers with newer drugs].
Topics: Adult; Anti-Ulcer Agents; Benzodiazepinones; Carbenoxolone; Cimetidine; Humans; Middle Aged; Peptic | 1983 |
Pirenzepine.
Topics: Anti-Ulcer Agents; Benzodiazepinones; Humans; Parasympatholytics; Peptic Ulcer; Pirenzepine | 1983 |
Effect of pirenzepine and antacids on postprandial intragastric pH.
Topics: Antacids; Benzodiazepinones; Dose-Response Relationship, Drug; Drug Therapy, Combination; Eating; Ga | 1983 |
[Retrospective study of the evaluation of peptic ulcer recurrence after 4 weeks of pirenzepin (Gastrozepin) treatment].
Topics: Benzodiazepinones; Humans; Peptic Ulcer; Pirenzepine; Recurrence; Retrospective Studies | 1983 |
[Mechanism of action of the gastric secretion inhibitor Pirenzepin].
Topics: Acetylcholine; Antacids; Anti-Ulcer Agents; Benzodiazepinones; Binding, Competitive; Blood-Brain Bar | 1980 |
[Stress-ulcer prevention with pirenzepine-a controlled study].
Topics: Benzodiazepinones; Double-Blind Method; Humans; Peptic Ulcer; Peptic Ulcer Hemorrhage; Piperazines; | 1980 |
[Conservative therapy of peptic ulcer].
Topics: Antacids; Benzodiazepinones; Cimetidine; Diazepam; Gastrointestinal Hormones; Humans; Hypnosis; Meto | 1980 |
Inhibition of gastric mucosa carbonic anhydrase by pirenzepine in patients with gastroduodenal ulcers.
Topics: Animals; Benzodiazepinones; Carbonic Anhydrase Inhibitors; Cattle; Duodenal Ulcer; Gastric Mucosa; H | 1981 |
[Pirenzepine--an anticholinergic agent with selective antimuscarinic properties].
Topics: Benzodiazepinones; Humans; Parasympatholytics; Peptic Ulcer; Pirenzepine; Receptors, Cholinergic; Re | 1982 |
Effect of pirenzepine on L--amino acids stimulated gastric acid secretion and serum gastrin levels in peptic ulcer disease in men.
Topics: Amino Acids; Benzodiazepinones; Female; Gastric Acid; Gastrins; Humans; Hydrogen-Ion Concentration; | 1982 |
[The possibilities of using gastrotsepin in treating digestive organ diseases].
Topics: Acute Disease; Adult; Antacids; Anti-Ulcer Agents; Chronic Disease; Digestive System Diseases; Drug | 1993 |
[New data on clinical response to therapeutic effects of gastrozepin].
Topics: Anti-Ulcer Agents; Duodenal Ulcer; Evaluation Studies as Topic; Humans; Peptic Ulcer; Pirenzepine; S | 1996 |
[The digestive activity of the chymus in the gastric stump in postgastrectomy peptic ulcers].
Topics: Digestion; Female; Gastrectomy; Gastric Acidity Determination; Gastroenterostomy; Gastrointestinal C | 1992 |
Addition of misoprostol to ranitidine in non-responders to H2-blockers and pirenzepine.
Topics: Alprostadil; Anti-Ulcer Agents; Drug Resistance; Drug Therapy, Combination; Gastric Acidity Determin | 1991 |
[The effect of cimetidine and gastrozepin on liver function and the pharmacotherapy of "hepatogenous" gastroduodenal ulcers and erosions].
Topics: Adult; Anti-Ulcer Agents; Chemical and Drug Induced Liver Injury; Cimetidine; Drug Evaluation; Drug | 1991 |
[Cardiac adverse effects following an intravenous injection of pirenzepine are an expression of deficient receptor sensitivity].
Topics: Adult; Aged; Aged, 80 and over; Female; Heart Rate; Humans; Injections, Intravenous; Male; Middle Ag | 1991 |
[Prevention of stress ulcer with topically acting drugs: an effective and sensible therapeutic approach? Arguments contra].
Topics: Antacids; Anti-Ulcer Agents; Cimetidine; Critical Care; Drug Therapy, Combination; Gastric Acidity D | 1991 |
[Clinical problems in the treatment and physiopathology of peptic ulcer in the aged].
Topics: Adult; Age Factors; Aged; Humans; Middle Aged; Peptic Ulcer; Pirenzepine; Recurrence | 1991 |
Combined effect of pirenzepine and ranitidine on the nocturnal intragastric pH in non-responders to ranitidine.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Circadian Rhythm; Drug Therapy, Combination; Fema | 1990 |
[Results of treatment of peptic ulcers using Gastrozepine and antacids in the endoscopic picture].
Topics: Adult; Antacids; Drug Therapy, Combination; Female; Gastroscopy; Humans; Male; Middle Aged; Peptic U | 1989 |
Moderate reduction of gastric acid secretion in the treatment of peptic ulcer disease.
Topics: Antacids; Bacteria; Benzodiazepinones; Cimetidine; Gastric Acid; Histamine H2 Antagonists; Humans; P | 1985 |
Present status and future perspectives of muscarinic receptor antagonists.
Topics: Animals; Drug Therapy, Combination; Gastric Acid; Histamine H2 Antagonists; Humans; Parasympatholyti | 1986 |
Anti-ulcer drugs in antisecretory doses for "cytoprotection" in arthritic patients?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis; Aspirin; Histamine H2 Antagon | 1986 |
[Comparative studies on recurrence and relapse rate in peptic ulcer treated with various types of anti-ulcer agent; inhibitors of initiating factors causing peptic ulcer].
Topics: Cimetidine; Histamine H2 Antagonists; Humans; Peptic Ulcer; Pirenzepine; Ranitidine; Recurrence | 1988 |
Plasma beta-endorphin immunoreactivity (PL-beta-ED-ir) in patients with ulcer disease and its management by acute and chronic administration of gastrozepin.
Topics: Administration, Oral; Benzodiazepinones; beta-Endorphin; Endorphins; Humans; Injections, Intramuscul | 1986 |
[New developments in the treatment of peptic ulcer].
Topics: Adult; Anti-Ulcer Agents; Drug Evaluation; Female; Humans; Male; Middle Aged; Organometallic Compoun | 1988 |
[Recent developments in drugs antagonistic to factors causing peptic ulcer--clinical efficacy and problems; muscarine M1 receptor blockaders].
Topics: Gastric Acid; Humans; Peptic Ulcer; Pirenzepine; Receptors, Muscarinic; Recurrence | 1988 |
The metabolic effects of acute and chronic administration of gastrozepin.
Topics: Administration, Oral; Adult; Blood Glucose; Catecholamines; Cholesterol; Duodenal Ulcer; Fatty Acids | 1987 |
Pirenzepin does not alter the pharmacokinetics of theophylline.
Topics: Adult; Drug Interactions; Humans; Kinetics; Male; Peptic Ulcer; Pirenzepine; Theophylline | 1987 |
[Drugs modifying motility in ulcer therapy].
Topics: Cisapride; Gastrointestinal Motility; Humans; Metoclopramide; Peptic Ulcer; Piperidines; Pirenzepine | 1987 |
[Comparative study of pirenzepine and ranitidine in the prevention of stress ulcer in patients in intensive care].
Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Benzodiazepinones; Critical Care; Female; Humans; Male; | 1986 |
Combination therapy with ranitidine and pirenzepine for control of intragastric pH in the critically ill.
Topics: Adolescent; Adult; Aged; Benzodiazepinones; Critical Care; Drug Evaluation; Drug Therapy, Combinatio | 1985 |
[Effect of metoclopramide, papaverine and gastrozepin on the myoelectrical activity of the stomach and small intestine].
Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Benzodiazepinones; Drug Evaluation; Electromyography; Fe | 1985 |
The risk of gastric dysplasia in medical long-term treatment of peptic ulcer disease.
Topics: Adult; Aged; Anti-Ulcer Agents; Benzodiazepinones; Cimetidine; Female; Humans; Male; Middle Aged; Pe | 1985 |