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pirenzepine and Gastritis

pirenzepine has been researched along with Gastritis in 14 studies

Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.

Gastritis: Inflammation of the GASTRIC MUCOSA, a lesion observed in a number of unrelated disorders.

Research Excerpts

ExcerptRelevanceReference
"The extent of acid secreting areas and the distribution of intestinal metaplasia in patients with erosive gastritis, and the healing effects of pirenzepine were examined."9.06Relationship of erosive gastritis to the acid secreting area and intestinal metaplasia, and the healing effect of pirenzepine. ( Iishi, H; Okuda, S; Tatsuta, M, 1987)
" Because it has been suggested that the lower relapse rate for duodenal ulcer following colloidal bismuth subcitrate (CBS) is due to suppression of C pylori we investigated different formulations and dosing of CBS for their efficacy in clearing C pylori."6.66Treatment of Campylobacter pylori gastritis: a pilot study using pirenzepine dihydrochloride (Gastrozepin) and three formulations of colloidal bismuth subcitrate (De-Nol). ( Ali, MR; Brown, P; Lane, M; Morris, A; Palmer, R, 1988)
"Antral biopsy specimens from 89 consecutive patients with nonulcer dyspepsia and erosive prepyloric changes included in a prospective, randomized, double-blind 4-wk study of the effect of an aluminum-magnesium antacid (120 mmol/day) or pirenzepine (50 mg b."5.06Antacids reduce Campylobacter pylori colonization without healing the gastritis in patients with nonulcer dyspepsia and erosive prepyloric changes. ( Alexander, B; Berstad, A; Hirschowitz, BI; Holland, S; Serck-Hanssen, A; Weberg, R, 1988)
"Pirenzepine (PRZ, 75 mg/day for 10 days followed by 50 mg/day for 20 days) was compared with placebo (PL) in the treatment of endoscopically confirmed active gastroduodenitis or duodenal ulcer and with carbenoxolone (CB, 300 mg/day followed by 200 mg/day) in the treatment of gastric ulcer in a 30-day double-blind clinical trial."5.04Pirenzepine in the treatment of benign gastroduodenal diseases. A double-blind controlled clinical trial. ( Cifani, G; D'Anchino, M; Di Tommaso, B; Gasbarrini, G; Giorgi-Conciato, M; Pesa, O; Sollecito, A, 1979)
" Because it has been suggested that the lower relapse rate for duodenal ulcer following colloidal bismuth subcitrate (CBS) is due to suppression of C pylori we investigated different formulations and dosing of CBS for their efficacy in clearing C pylori."2.66Treatment of Campylobacter pylori gastritis: a pilot study using pirenzepine dihydrochloride (Gastrozepin) and three formulations of colloidal bismuth subcitrate (De-Nol). ( Ali, MR; Brown, P; Lane, M; Morris, A; Palmer, R, 1988)
"Chronic alcoholic gastritis is a very important social problem in the Health District of Arezzo, which covers an area where wine is an integral part of the diet."2.66[Alcoholic gastropathy. Notes on its epidemiology and the therapeutic experience using pirenzepine]. ( Agnolucci, A; Angioli, D; Caneschi, F; Cucinelli, ML; Magnolfi, F; Pichi, V; Rossi, G; Valentini, P, 1986)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199013 (92.86)18.7374
1990's0 (0.00)18.2507
2000's1 (7.14)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Serebrova, SIu1
Lagarde, SP1
Spiro, HM1
Giorgi-Conciato, M2
Daniotti, S1
Ferrari, PA1
Gaetani, M1
Petrin, G1
Sala, P1
Valentini, P3
Giaccari, S1
Tronci, S1
De Maria, E1
Chirletti, P1
Colobraro, P1
Romano, R1
Barzi, A1
Mangialardi, N1
Bertoldi, I1
Cirenei, A1
Plottin, F1
Capony, P1
Meullenet, J1
Fournet, J1
Gasbarrini, G1
D'Anchino, M1
Di Tommaso, B1
Pesa, O1
Sollecito, A1
Cifani, G1
Morris, A1
Brown, P1
Ali, MR1
Lane, M1
Palmer, R1
Kishimoto, S1
Kobuke, K1
Kobayashi, H1
Kato, R1
Kajiyama, G1
Miyoshi, A1
Weberg, R2
Berstad, A2
Alexander, B1
Serck-Hanssen, A1
Holland, S1
Hirschowitz, BI1
Tatsuta, M1
Iishi, H1
Okuda, S1
Toft, E1
Kristensen, OK1
Magnolfi, F1
Agnolucci, A1
Rossi, G1
Caneschi, F1
Pichi, V1
Cucinelli, ML1
Angioli, D1

Reviews

1 review available for pirenzepine and Gastritis

ArticleYear
Non-ulcer dyspepsia.
    Clinics in gastroenterology, 1984, Volume: 13, Issue:2

    Topics: Antacids; Benzodiazepinones; Diet; Duodenitis; Dyspepsia; Gastric Acid; Gastritis; Gastrointestinal

1984

Trials

7 trials available for pirenzepine and Gastritis

ArticleYear
Efficacy and safety of pirenzepine in peptic ulcer and in non ulcerous gastroduodenal diseases. A multicentre controlled clinical trial.
    Scandinavian journal of gastroenterology. Supplement, 1982, Volume: 81

    Topics: Adult; Benzodiazepinones; Carbenoxolone; Cimetidine; Clinical Trials as Topic; Duodenal Ulcer; Duode

1982
Pirenzepine in the treatment of benign gastroduodenal diseases. A double-blind controlled clinical trial.
    Scandinavian journal of gastroenterology. Supplement, 1979, Volume: 57

    Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Benzodiazepinones; Clinical Trials as Topic; Double-Blin

1979
Treatment of Campylobacter pylori gastritis: a pilot study using pirenzepine dihydrochloride (Gastrozepin) and three formulations of colloidal bismuth subcitrate (De-Nol).
    The New Zealand medical journal, 1988, Oct-26, Volume: 101, Issue:856 Pt 1

    Topics: Administration, Oral; Adult; Biopsy; Bismuth; Campylobacter; Campylobacter Infections; Clinical Tria

1988
Low-dose antacids and pirenzepine in the treatment of patients with non-ulcer dyspepsia and erosive prepyloric changes. A randomized, double-blind, placebo-controlled trial.
    Scandinavian journal of gastroenterology, 1988, Volume: 23, Issue:2

    Topics: Adult; Antacids; Clinical Trials as Topic; Double-Blind Method; Dyspepsia; Female; Gastric Mucosa; G

1988
Antacids reduce Campylobacter pylori colonization without healing the gastritis in patients with nonulcer dyspepsia and erosive prepyloric changes.
    Gastroenterology, 1988, Volume: 95, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antacids; Campylobacter; Clinical Trials as Topic; Double-Blind Meth

1988
Relationship of erosive gastritis to the acid secreting area and intestinal metaplasia, and the healing effect of pirenzepine.
    Gut, 1987, Volume: 28, Issue:5

    Topics: Adult; Aged; Biopsy; Clinical Trials as Topic; Double-Blind Method; Female; Gastric Mucosa; Gastriti

1987
[Alcoholic gastropathy. Notes on its epidemiology and the therapeutic experience using pirenzepine].
    Minerva medica, 1986, Oct-13, Volume: 77, Issue:39

    Topics: Adult; Aged; Alcoholism; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Female; Gas

1986

Other Studies

6 other studies available for pirenzepine and Gastritis

ArticleYear
[The clinical effectiveness of rabeprazole in patients with acid-related gastric and duodenal diseases with various sensitivity of different types of parietal gastric cell receptors].
    Klinicheskaia meditsina, 2007, Volume: 85, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Female; Gastric Acid; Gastric Aci

2007
[Pirenzepin in the treatment of toxic gastroduodenitis in chronic alcoholics].
    La Clinica terapeutica, 1984, Jun-15, Volume: 109, Issue:5

    Topics: Alcoholism; Benzodiazepinones; Drug Evaluation; Duodenitis; Gastritis; Humans; Pirenzepine

1984
[Pirenzepine parenterally administered in high doses in the treatment of upper digestive hemorrhage].
    Minerva medica, 1984, Jan-14, Volume: 75, Issue:1-2

    Topics: Adult; Aged; Benzodiazepinones; Duodenitis; Female; Gastritis; Gastrointestinal Hemorrhage; Humans;

1984
[Treatment of Ménétrier's disease with pirenzepine].
    Gastroenterologie clinique et biologique, 1983, Volume: 7, Issue:12

    Topics: Aged; Benzodiazepinones; Gastritis; Gastritis, Hypertrophic; Humans; Male; Pirenzepine

1983
Preventive effect of pirenzepine on atrophic erosive gastritis in rats.
    Hiroshima journal of medical sciences, 1988, Volume: 37, Issue:3

    Topics: Animals; Gastritis; Gastritis, Atrophic; Male; Pirenzepine; Rats; Rats, Inbred Strains; Taurocholic

1988
[Menetrier's disease treated with pirenzepine].
    Ugeskrift for laeger, 1988, Feb-08, Volume: 150, Issue:6

    Topics: Adult; Female; Gastritis; Gastritis, Atrophic; Humans; Male; Pirenzepine

1988