Page last updated: 2024-11-02

pirenzepine and Gastric Ulcer

pirenzepine has been researched along with Gastric Ulcer in 83 studies

Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.

Research Excerpts

ExcerptRelevanceReference
"Fifty-five patients with endoscopically confirmed gastric ulcers received either cimetidine (28 patients) or pirenzepine (27 patients) in a randomized double-blind manner."9.06Gastric ulcer: a double-blind comparison of 100 mg pirenzepine plus antacid versus 800 mg cimetidine plus antacid. ( Arnold, J; Birchler, R; Bretholz, A; Capitaine, Y; Gonvers, JJ; Guyot, J; Ollyo, JB; Realini, S; Voirol, M, 1986)
"163 patients with endoscopically proven benign gastric ulcers were randomly allocated to treatment with either telenzepine 3 mg nocte or ranitidine 300 mg nocte for up to 8 weeks in a prospective double-blind study."9.06[3 mg telenzepine nocte in the treatment of benign stomach ulcer disease: a double-blind comparative study with 300 mg ranitidine nocte]. ( Dammann, HG; Müller, P; Reinicke, HG; Simon, B, 1990)
"In a double-blind, multicentre study 77 patients with benign gastric ulcer were randomly allocated to treatment with either enprostil 35 micrograms bd or pirenzepine 50 mg bd."9.06Enprostil, a prostaglandin E2 analogue, in the treatment of gastric ulcer--a multicentre comparison with pirenzepine. ( Carr-Locke, D; English, JR; Jazrawi, RP; Mountford, RA; Northfield, TC; Reed, PI; Schiller, KF; Williams, JG, 1990)
"The purpose of the present study was to compare the effectiveness of pirenzepine and carbenoxolone in accelerating the healing of chronic gastric ulcer."9.05Comparison of pirenzepine and carbenoxolone in the treatment of chronic gastric ulcer. A double-blind endoscopic trial. ( Bianchi Porro, G; Daniotti, S; De Pretis, G; Dobrilla, G; Lazzaroni, M; Mazzacca, G; Petrillo, M; Piai, G; Sabbatini, F, 1985)
"The gastric cytoprotective effects of vitamin A, De-Nol and sucralfate were compared with the effectiveness of pirenzepine in healing ulcer in patients with chronic gastric ulcer."9.05A comparative dynamic study of the effectiveness of gastric cytoprotection by vitamin A, De-Nol, sucralfate and ulcer healing by pirenzepine in patients with chronic gastric ulcer (a multiclinical and randomized study). ( Benedek, S; Deák, G; Jávor, T; Kenéz, P; Mózsik, G; Nagy, L; Patty, I; Simon, L; Tárnok, F, 1984)
"37 patients with endoscopically confirmed gastric ulcers received either cimetidine (19 patients) or pirenzepine (18 patients) in a double-blind trial."9.05[Treatment of stomach ulcers with cimetidine and pirenzepine]. ( Arnold, J; Birchler, R; Bretholz, A; Capitaine, Y; Gonvers, JJ; Realini, S; Voirol, M, 1984)
"The therapeutic effects on gastric ulcer and side-effects of 5,11-dihydro-11[(4-methyl-1-piperazinyl)acetyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6 one-dihydrochloride (pirenzepine, LS519), a new antiulcer drug, were investigated in 15 medical institutes by a double-blind controlled clinical study, using trans-3,7-dimethyl-2,6-octadienyl-5,9,13-trimethyltetradeca-4,8,12-trienoate (gefarnate) as the standard drug."9.05Therapeutic effect of pirenzepine dihydrochloride on gastric ulcer evaluated by a double-blind controlled clinical study. Phase III study. ( Ishimori, A; Yamagata, S, 1982)
"The effectiveness of pirenzepine in the treatment of gastric ulcer was assessed in a double-blind 6 weeks' clinical trial in comparison with placebo."9.04Pirenzepine in the treatment of gastric ulcer. A double-blind short-term clinical trial. ( Morelli, A; Narducci, F; Pelli, A; Spadacini, A, 1979)
"Pirenzepine (PRZ) 75 mg/day for 1 week followed by 50 mg/day for 3 weeks did not show a good activity in gastric ulcer healing in comparison to carbenoxolone (CB) (300 mg/day for 1 week followed by 200 mg/day for 3 weeks)."9.04Pirenzepine and carbenozolone in gastric ulcer. Preliminary results of a multicentre double-blind controlled clinical trial. ( Barbara, L; Belsasso, E; Blasi, A; Caenazzo, E; Di Febo, G; Di Mario, F; Giorgi-Conciato, M; Marletta, F; Miglioli, M; Petrillo, M; Salvagnini, M; Scalabrin, G, 1979)
" The pharmacokinetics of pirenzepine (Gastrozepin) was studied after single and multiple oral administration in gastric ulcer and duodenal ulcer patients."7.67Pharmacokinetics of pirenzepine in patients with gastric or duodenal ulcers. ( Bozler, G; Hayakawa, A; Kobayashi, S; Misawa, T; Nishihara, S, 1987)
"We studied the effects of atropine and pirenzepine on acid secretion induced by electrical vagal stimulation (EVS) and on healing of gastric ulcers after mucosal excision in rats."7.67Effects of atropine and pirenzepine on healing of gastric ulcer induced by mucosal excision in rats. ( Fujiwara, M; Kitagawa, H; Sano, M, 1985)
"Pirenzepine (Gastrozepin) is a drug recently introduced in the therapy of gastroduodenal ulcer (GDU)."7.66Inhibition of gastric mucosa carbonic anhydrase by pirenzepine in patients with gastroduodenal ulcers. ( Búzás, G; Domuta, M; Puşcaş, I; Surányi, P, 1981)
"The effects of pirenzepine on the serum gastrin levels in the basal state and in response to a liquid test meal were investigated in nine patients with gastric ulcer."7.66Inhibition of gastrin secretion by pirenzepine (LS 519) in treatment of gastric ulcer. ( Baba, M; Itoh, T; Okuda, S; Tamura, H; Tatsuta, M; Yamamura, H, 1981)
"Pirenzepine has been reported to inhibit gastrin secretion."6.68Effects of pirenzepine on omeprazole-induced hypergastrinemia and acid suppression in peptic ulcer patients. ( Fukino, Y; Hamada, M; Haruma, K; Inoue, M; Kajiyama, G; Kamiyasu, T; Sumii, K; Sumii, M; Tari, A, 1996)
"The pneumonia rate in ranitidine-, pirenzepine-, and placebo-treated patients is 10 of 57, 10 of 44, and 12 of 57, respectively."5.08A randomized, double-blind trial for stress ulcer prophylaxis shows no evidence of increased pneumonia. ( Encke, A; Hanisch, EW; Naujoks, F; Windolf, J, 1998)
"Serum gastrin levels in 44 peptic ulcer patients (26 gastric ulcer patients and 18 duodenal ulcer patients) were determined after they had been treated with omeprazole (OPZ) (20 mg/day) alone or in combination with pirenzepine (PZP) (100 mg/day)."5.07Serum gastrin levels following administration of omeprazole alone or in combination with pirenzepine. ( Arakawa, Y; Ito, K; Iwasaki, A; Kawamura, Y; Matsuo, Y; Miyazawa, K; Sakai, Y; Tashiro, Y, 1994)
"163 patients with endoscopically proven benign gastric ulcers were randomly allocated to treatment with either telenzepine 3 mg nocte or ranitidine 300 mg nocte for up to 8 weeks in a prospective double-blind study."5.06[3 mg telenzepine nocte in the treatment of benign stomach ulcer disease: a double-blind comparative study with 300 mg ranitidine nocte]. ( Dammann, HG; Müller, P; Reinicke, HG; Simon, B, 1990)
"In a double-blind, multicentre study 77 patients with benign gastric ulcer were randomly allocated to treatment with either enprostil 35 micrograms bd or pirenzepine 50 mg bd."5.06Enprostil, a prostaglandin E2 analogue, in the treatment of gastric ulcer--a multicentre comparison with pirenzepine. ( Carr-Locke, D; English, JR; Jazrawi, RP; Mountford, RA; Northfield, TC; Reed, PI; Schiller, KF; Williams, JG, 1990)
"Fifty-five patients with endoscopically confirmed gastric ulcers received either cimetidine (28 patients) or pirenzepine (27 patients) in a randomized double-blind manner."5.06Gastric ulcer: a double-blind comparison of 100 mg pirenzepine plus antacid versus 800 mg cimetidine plus antacid. ( Arnold, J; Birchler, R; Bretholz, A; Capitaine, Y; Gonvers, JJ; Guyot, J; Ollyo, JB; Realini, S; Voirol, M, 1986)
"The gastric cytoprotective effects of vitamin A, De-Nol and sucralfate were compared with the effectiveness of pirenzepine in healing ulcer in patients with chronic gastric ulcer."5.05A comparative dynamic study of the effectiveness of gastric cytoprotection by vitamin A, De-Nol, sucralfate and ulcer healing by pirenzepine in patients with chronic gastric ulcer (a multiclinical and randomized study). ( Benedek, S; Deák, G; Jávor, T; Kenéz, P; Mózsik, G; Nagy, L; Patty, I; Simon, L; Tárnok, F, 1984)
"37 patients with endoscopically confirmed gastric ulcers received either cimetidine (19 patients) or pirenzepine (18 patients) in a double-blind trial."5.05[Treatment of stomach ulcers with cimetidine and pirenzepine]. ( Arnold, J; Birchler, R; Bretholz, A; Capitaine, Y; Gonvers, JJ; Realini, S; Voirol, M, 1984)
"In two studies the beneficial effect of Pirenzepine in the treatment of peptic duodenal and gastric ulcers was investigated in 1686 outpatients."5.05[Treatment of ulcers with pirenzepin. Results from clinic and practice]. ( Kalk, A; Krempler, F; Sandhofer, F, 1982)
"The therapeutic effects on gastric ulcer and side-effects of 5,11-dihydro-11[(4-methyl-1-piperazinyl)acetyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6 one-dihydrochloride (pirenzepine, LS519), a new antiulcer drug, were investigated in 15 medical institutes by a double-blind controlled clinical study, using trans-3,7-dimethyl-2,6-octadienyl-5,9,13-trimethyltetradeca-4,8,12-trienoate (gefarnate) as the standard drug."5.05Therapeutic effect of pirenzepine dihydrochloride on gastric ulcer evaluated by a double-blind controlled clinical study. Phase III study. ( Ishimori, A; Yamagata, S, 1982)
"The purpose of the present study was to compare the effectiveness of pirenzepine and carbenoxolone in accelerating the healing of chronic gastric ulcer."5.05Comparison of pirenzepine and carbenoxolone in the treatment of chronic gastric ulcer. A double-blind endoscopic trial. ( Bianchi Porro, G; Daniotti, S; De Pretis, G; Dobrilla, G; Lazzaroni, M; Mazzacca, G; Petrillo, M; Piai, G; Sabbatini, F, 1985)
"Pirenzepine (PRZ) 75 mg/day for 1 week followed by 50 mg/day for 3 weeks did not show a good activity in gastric ulcer healing in comparison to carbenoxolone (CB) (300 mg/day for 1 week followed by 200 mg/day for 3 weeks)."5.04Pirenzepine and carbenozolone in gastric ulcer. Preliminary results of a multicentre double-blind controlled clinical trial. ( Barbara, L; Belsasso, E; Blasi, A; Caenazzo, E; Di Febo, G; Di Mario, F; Giorgi-Conciato, M; Marletta, F; Miglioli, M; Petrillo, M; Salvagnini, M; Scalabrin, G, 1979)
"The effectiveness of pirenzepine in the treatment of gastric ulcer was assessed in a double-blind 6 weeks' clinical trial in comparison with placebo."5.04Pirenzepine in the treatment of gastric ulcer. A double-blind short-term clinical trial. ( Morelli, A; Narducci, F; Pelli, A; Spadacini, A, 1979)
"Pirenzepine (PRZ, 75 mg/day for 10 days followed by 50 mg/day for 20 days) was compared with placebo (PL) in the treatment of endoscopically confirmed active gastroduodenitis or duodenal ulcer and with carbenoxolone (CB, 300 mg/day followed by 200 mg/day) in the treatment of gastric ulcer in a 30-day double-blind clinical trial."5.04Pirenzepine in the treatment of benign gastroduodenal diseases. A double-blind controlled clinical trial. ( Cifani, G; D'Anchino, M; Di Tommaso, B; Gasbarrini, G; Giorgi-Conciato, M; Pesa, O; Sollecito, A, 1979)
"The healing rate of duodenal ulcers may be accelerated by secretory inhibitors such as histamine H2-receptor antagonists and pirenzepine, by antacids, by protective drugs such as sucralfate and colloidal bismuth, and by antidepressant drugs such as trimipramine."4.77Therapeutic approach to ulcer healing. ( Blum, AL, 1985)
"A randomized, prospective, interventional trial was performed comparing pirenzepine (muscarinic type I receptor antagonist) and ephedrine (nonspecific sympathomimetic) in the prevention of gastric ulcerogenesis after CCT in the rat."3.70Autonomic regulation of gastric ulcerogenesis after cervical cord transection in the rat. ( Strain, GM; Waldrop, RD, 1998)
" The compound had no activity against cysteamine-induced duodenal ulcers and lost its cytoprotective activity in adrenalectomised rats."3.68BAY P 1455, a thiazolylaminobenzimidazole derivative with gastroprotective properties in the rat. ( Bruno, M; Grassi, A; Ippen, J; Thomas, G, 1991)
" The pharmacokinetics of pirenzepine (Gastrozepin) was studied after single and multiple oral administration in gastric ulcer and duodenal ulcer patients."3.67Pharmacokinetics of pirenzepine in patients with gastric or duodenal ulcers. ( Bozler, G; Hayakawa, A; Kobayashi, S; Misawa, T; Nishihara, S, 1987)
"We studied the effects of atropine and pirenzepine on acid secretion induced by electrical vagal stimulation (EVS) and on healing of gastric ulcers after mucosal excision in rats."3.67Effects of atropine and pirenzepine on healing of gastric ulcer induced by mucosal excision in rats. ( Fujiwara, M; Kitagawa, H; Sano, M, 1985)
"The effects of pirenzepine on the serum gastrin levels in the basal state and in response to a liquid test meal were investigated in nine patients with gastric ulcer."3.66Inhibition of gastrin secretion by pirenzepine (LS 519) in treatment of gastric ulcer. ( Baba, M; Itoh, T; Okuda, S; Tamura, H; Tatsuta, M; Yamamura, H, 1981)
"Pirenzepine (Gastrozepin) is a drug recently introduced in the therapy of gastroduodenal ulcer (GDU)."3.66Inhibition of gastric mucosa carbonic anhydrase by pirenzepine in patients with gastroduodenal ulcers. ( Búzás, G; Domuta, M; Puşcaş, I; Surányi, P, 1981)
"Pirenzepine has been reported to inhibit gastrin secretion."2.68Effects of pirenzepine on omeprazole-induced hypergastrinemia and acid suppression in peptic ulcer patients. ( Fukino, Y; Hamada, M; Haruma, K; Inoue, M; Kajiyama, G; Kamiyasu, T; Sumii, K; Sumii, M; Tari, A, 1996)
"A total of 120 patients suffering from brain tumors was included in this study."2.66[Report of experience with stomach-protective therapy in high-dosage corticosteroid treatment of patients with brain tumors]. ( Hirschl, M, 1988)
"Pirenzepine is a new anticholinergic agent which selectively binds to gastric mucosal muscarinic receptors."2.36The efficacy and selectivity of pirenzepine. Review and commentary. ( Reilly, PA; Texter, EC, 1982)
" Omeprazole, which suppresses acid very effectively, may be problematic in the critically ill, limited by its oral dosage form, acid-labile properties, and potential drug interactions."1.28Controlling gastric pH: the impact of newer agents on the critically ill patient. ( Earnest, DL, 1990)
"But pirenzepine has also been found to have a cytoprotective effect on gastric mucosa in rats."1.27Cytoprotective effect of pirenzepine and palm wine on rats gastric mucosa. ( Ezeamuzie, IC; Ibu, JO; Ngeribara, CO; Obuforoibo, AA, 1986)

Research

Studies (83)

TimeframeStudies, this research(%)All Research%
pre-199055 (66.27)18.7374
1990's27 (32.53)18.2507
2000's1 (1.20)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lattanzi, A1
Del Soldato, P2
Simon, B2
Müller, P2
Dammann, HG2
Giorgi-Conciato, M3
Daniotti, S2
Ferrari, PA1
Gaetani, M1
Petrin, G1
Sala, P1
Valentini, P1
Klincewicz, H2
Hasik, J2
Hryniewiecki, L1
Grigor'ev, IIa1
Zhivodereov, VM1
Khar'kovskiĭ, NN1
Patty, I1
Tárnok, F1
Simon, L1
Jávor, T1
Deák, G1
Benedek, S1
Kenéz, P1
Nagy, L1
Mózsik, G1
Brühlmann, W1
von Büren, U1
Zollikofer, C1
Müller-Lissner, S1
Blum, A1
Bernardini, C2
Martinotti, E2
Del Tacca, M2
Soldani, G2
Bertelli, A2
Gonvers, JJ2
Realini, S2
Bretholz, A2
Voirol, M2
Arnold, J2
Birchler, R2
Capitaine, Y2
Kukes, VG1
Blinkov, Il1
Chekhmakina, OV1
Krivorotova, SP1
Karpenko, EV1
Pellegrini, M1
Hopkins, S1
Varin, L2
Foschi, D1
De Rosa, M1
Nakamura, K1
Sunaga, H1
Texter, EC1
Reilly, PA1
Krempler, F1
Sandhofer, F1
Kalk, A1
Gibiński, K1
Nowak, A1
Marlicz, K1
Gabryelewicz, A1
Kosidło, S1
Mattes, P1
Peros, G1
Belohlavek, D1
Merkle, N1
Kilian, J1
Puşcaş, I1
Búzás, G1
Surányi, P1
Domuta, M1
Tatsuta, M1
Itoh, T1
Okuda, S1
Tamura, H1
Baba, M1
Yamamura, H1
Berndt, H1
Otto, R1
Cerlek, S1
Papa, B1
Katicić, M1
Colić-Cvrlje, V1
Mielenz, H2
Mittelstaedt, A1
Zilly, A1
Verhoeven, A1
Ishimori, A2
Yamagata, S1
Nikolaeva, NN1
Grishchenko, EG1
Nikolaeva, LV1
Grigor'ev, PIa1
Iakovenko, AV1
Vasil'ev, IV1
Takase, H1
Yamamoto, K1
Hirano, H1
Saito, Y1
Yamashita, A1
Behrens, R1
Hofbeck, M1
Singer, H1
Scharf, J1
Rupprecht, T1
Iwasaki, A1
Miyazawa, K1
Kawamura, Y1
Sakai, Y1
Tashiro, Y1
Ito, K1
Arakawa, Y1
Matsuo, Y1
Kosaka, N1
Tanaka, H1
Tomaru, A1
Ishii, A1
Shuto, K1
Takakura, K2
Harada, J2
Mizogami, M2
Goto, Y2
Urakawa, T1
Nagahata, Y1
Kawakita, N1
Tari, A1
Hamada, M1
Kamiyasu, T1
Fukino, Y1
Sumii, M1
Haruma, K1
Sumii, K1
Inoue, M1
Kajiyama, G1
Zaĭtseva, EI1
Titova, OV1
Melekhova, LS1
Makarenko, TG1
Sosina, TE1
Karateev, AE1
Murav'ev, IuV1
Nasonova, VA1
Waldrop, RD1
Strain, GM1
Hanisch, EW1
Encke, A1
Naujoks, F1
Windolf, J1
Vakhrushev, IaM1
Muravtseva, OV1
Barbara, L1
Belsasso, E1
Blasi, A1
Caenazzo, E1
Di Febo, G1
Di Mario, F1
Marletta, F1
Miglioli, M1
Petrillo, M2
Salvagnini, M1
Scalabrin, G1
Gasbarrini, G1
D'Anchino, M1
Di Tommaso, B1
Pesa, O1
Sollecito, A1
Cifani, G1
Oselladore, D1
Chierichetti, SM1
Norberto, L1
Vibelli, C1
Morelli, A1
Pelli, A1
Narducci, F1
Spadacini, A1
Kojima, Y1
Ishihara, K1
Ohara, S1
Saigenji, K1
Hotta, K1
Kawamura, T1
Koizumi, F1
Natsvlishvili, NA1
Samonina, GE1
Ashmarin, IP1
Sigman, HH1
Poleski, MH1
Gillich, A1
Grassi, A1
Ippen, J1
Bruno, M1
Thomas, G1
Earnest, DL1
Kromer, W2
Gönne, S1
Riedel, R2
Postius, S1
Kawakami, H1
Miyata, K1
Kamato, T1
Nishida, A1
Honda, K1
Reed, PI1
Jazrawi, RP1
Northfield, TC1
Carr-Locke, D1
Mountford, RA1
Williams, JG1
Schiller, KF1
English, JR1
Reinicke, HG1
Ibáñez Delgado, F1
Torreblanca López, J1
López-Campos, JL2
Moreno Onorato, FJ1
Pekhlivanov, D1
Rankov, R1
Pekhlivanov, N1
Lambev, I1
Minkova, N1
Albrecht, R1
Nowak, W1
Kitagawa, H4
Takeda, F3
Kohei, H3
Rainsford, KD1
Madrid, JA1
Salido, GM1
Muñoz-Arrebola, P1
Martínez de Victoria, E1
Blum, AL1
Laggner, AN1
Lenz, K1
Morikawa, K1
Aratani, T1
Mizutani, F1
Kato, H1
Ito, Y1
Stockbrügger, RW1
Cronstedt, J1
Dotevall, G1
Hellner, L1
Hoffmann, P1
Hradsky, M1
Jaup, BH1
Seeberg, S1
Zheng, W1
Yong, DG1
Geng, BQ1
Gu, GG1
Martí-Cabrera, M1
Esplugues, JV1
Martí-Bonmati, L1
Sarria, B1
Vento, A1
Martí-Bonmati, E1
Gil, L1
Esplugues, J1
Ibáñez, F1
Torreblanca, J1
Moreno, FJ1
Bohnenkamp, W1
Eltze, M1
Heintze, K1
Prinz, W1
Hirschl, M1
Hayashi, T1
Kinekawa, F1
Giachetti, A1
Brambilla, A1
Ibu, JO1
Obuforoibo, AA1
Ezeamuzie, IC1
Ngeribara, CO1
Ollyo, JB1
Guyot, J1
Takano, KI1
Sugiyama, S1
Nakazawa, S1
Ozawa, T1
Hayakawa, A1
Misawa, T1
Nishihara, S1
Kobayashi, S1
Bozler, G1
Stockbrügger, R1
Sano, M1
Fujiwara, M1
Polloni, A1
Marchi, S1
Bellini, M1
Savalli, E1
Cecconi, N1
Vanacore, R1
Grassi, B1
Cameron, AD1
Bianchi Porro, G1
Lazzaroni, M1
Mazzacca, G1
Sabbatini, F1
Piai, G1
Dobrilla, G1
De Pretis, G1
Hoffenberg, P1
Maggiolo, P1
Ossa, P1
Gallo, G1
Klinger, J1

Reviews

4 reviews available for pirenzepine and Gastric Ulcer

ArticleYear
[Acid anti-secretion therapy in gastric and duodenal ulcer].
    La Clinica terapeutica, 1981, Oct-31, Volume: 99, Issue:2

    Topics: Antacids; Anti-Ulcer Agents; Benzodiazepinones; Cimetidine; Duodenal Ulcer; Furans; Gastric Juice; G

1981
[Gastrozepin--a new anti-ulcer agent (a review of the literature and the authors' own data)].
    Terapevticheskii arkhiv, 1984, Volume: 56, Issue:2

    Topics: Animals; Anti-Ulcer Agents; Benzodiazepinones; Cimetidine; Drug Evaluation; Drug Synergism; Duodenal

1984
The efficacy and selectivity of pirenzepine. Review and commentary.
    Scandinavian journal of gastroenterology. Supplement, 1982, Volume: 72

    Topics: Anti-Ulcer Agents; Benzodiazepinones; Duodenal Ulcer; Endoscopy; Humans; Pirenzepine; Stomach Ulcer

1982
Therapeutic approach to ulcer healing.
    The American journal of medicine, 1985, Aug-30, Volume: 79, Issue:2C

    Topics: Aluminum; Antacids; Anti-Ulcer Agents; Antidepressive Agents; Benzodiazepinones; Bismuth; Colloids;

1985

Trials

32 trials available for pirenzepine and Gastric Ulcer

ArticleYear
[Antisecretory and mucosa-protecting drugs in the acute care of peptic ulcer. Review of action principles, healing rates and side effects of approved ulcer drugs and drugs under clinical trial].
    Fortschritte der Medizin, 1984, Jul-12, Volume: 102, Issue:25-26

    Topics: Acute Disease; Aluminum; Antacids; Anti-Ulcer Agents; Benzodiazepinones; Cimetidine; Clinical Trials

1984
Efficacy and safety of pirenzepine in peptic ulcer and in non ulcerous gastroduodenal diseases. A multicentre controlled clinical trial.
    Scandinavian journal of gastroenterology. Supplement, 1982, Volume: 81

    Topics: Adult; Benzodiazepinones; Carbenoxolone; Cimetidine; Clinical Trials as Topic; Duodenal Ulcer; Duode

1982
[Double-blind study on therapy with new drugs in stomach and duodenal ulcers].
    Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1983, Volume: 43, Issue:1

    Topics: Adult; Anti-Ulcer Agents; Benzodiazepinones; Double-Blind Method; Duodenal Ulcer; Duodenoscopy; Fema

1983
A comparative dynamic study of the effectiveness of gastric cytoprotection by vitamin A, De-Nol, sucralfate and ulcer healing by pirenzepine in patients with chronic gastric ulcer (a multiclinical and randomized study).
    Acta physiologica Hungarica, 1984, Volume: 64, Issue:3-4

    Topics: Adolescent; Adult; Aged; Aluminum; Antacids; Anti-Ulcer Agents; Benzodiazepinones; Bismuth; Clinical

1984
[Gastric secretory inhibitors improve the visibility of gastric mucosal detail in barium studies of the stomach: a controlled clinical trial (author's transl)].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1981, Volume: 134, Issue:6

    Topics: Benzodiazepinones; Cimetidine; Depression, Chemical; Gastric Emptying; Gastric Juice; Guanidines; Hu

1981
[Treatment of stomach ulcers with cimetidine and pirenzepine].
    Schweizerische medizinische Wochenschrift, 1984, May-19, Volume: 114, Issue:20

    Topics: Anti-Ulcer Agents; Benzodiazepinones; Cimetidine; Female; Humans; Male; Middle Aged; Pirenzepine; St

1984
[Treatment of ulcers with pirenzepin. Results from clinic and practice].
    Wiener medizinische Wochenschrift (1946), 1982, Sep-30, Volume: 132, Issue:18

    Topics: Adult; Anti-Ulcer Agents; Benzodiazepinones; Carbenoxolone; Chemical Phenomena; Chemistry; Cimetidin

1982
[Multicenter controlled clinical studies on the effectiveness of pirenzepin in the treatment of peptic ulcer].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1982, Nov-08, Volume: 37, Issue:43

    Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Benzodiazepinones; Clinical Trials as Topic; Duodenal Ul

1982
Pirenzepin in gastric and duodenal ulcer: a double-blind trial.
    The Journal of international medical research, 1981, Volume: 9, Issue:2

    Topics: Aged; Benzodiazepinones; Clinical Trials as Topic; Double-Blind Method; Duodenal Ulcer; Female; Huma

1981
[Results of a controlled comparative study between cimetidine and pirenzepin in 60 patients with ulcera ventriculi or duodeni].
    Fortschritte der Medizin, 1981, Nov-12, Volume: 99, Issue:42

    Topics: Anti-Ulcer Agents; Benzodiazepinones; Cimetidine; Clinical Trials as Topic; Duodenal Ulcer; Guanidin

1981
Therapeutic effect of pirenzepine dihydrochloride on gastric ulcer evaluated by a double-blind controlled clinical study. Phase III study.
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:5

    Topics: Adult; Aged; Anti-Ulcer Agents; Benzodiazepinones; Clinical Trials as Topic; Double-Blind Method; Fe

1982
Frequency of stress lesions of the upper gastrointestinal tract in paediatric patients after cardiac surgery: effects of prophylaxis.
    British heart journal, 1994, Volume: 72, Issue:2

    Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Famotidine; Female; Heart Defects, Congenit

1994
Serum gastrin levels following administration of omeprazole alone or in combination with pirenzepine.
    Journal of gastroenterology, 1994, Volume: 29, Issue:4

    Topics: Drug Therapy, Combination; Duodenal Ulcer; Gastrins; Humans; Omeprazole; Peptic Ulcer; Pirenzepine;

1994
Prophylactic effects of pirenzepine (M1-blocker) on intraoperative stress ulcer: comparison with an H2-blocker.
    Anesthesia and analgesia, 1994, Volume: 78, Issue:1

    Topics: Adult; Gastric Juice; Gastric Mucosa; Humans; Hydrogen-Ion Concentration; Intraoperative Care; Intra

1994
Effect of pirenzepine on postoperative gastric secretion.
    The Kobe journal of medical sciences, 1993, Volume: 39, Issue:2

    Topics: Adult; Aged; Female; Gastric Acid; Gastric Acidity Determination; Gastric Mucosa; Humans; Male; Midd

1993
Effects of pirenzepine on omeprazole-induced hypergastrinemia and acid suppression in peptic ulcer patients.
    Journal of gastroenterology, 1996, Volume: 31, Issue:2

    Topics: Adult; Aged; Anti-Ulcer Agents; Drug Therapy, Combination; Duodenal Ulcer; Female; Gastric Acid; Gas

1996
[The endoscopic assessment of the effect of ranitidine and pirenzepine on the manifestations of the gastropathy induced by nonsteroidal anti-inflammatory preparations].
    Terapevticheskii arkhiv, 1997, Volume: 69, Issue:5

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Female; Gastroscopy; Histamine H2

1997
A randomized, double-blind trial for stress ulcer prophylaxis shows no evidence of increased pneumonia.
    American journal of surgery, 1998, Volume: 176, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Double-Blind Method; Female; Histamin

1998
Pirenzepine and carbenozolone in gastric ulcer. Preliminary results of a multicentre double-blind controlled clinical trial.
    Scandinavian journal of gastroenterology. Supplement, 1979, Volume: 57

    Topics: Anti-Ulcer Agents; Benzodiazepinones; Carbenoxolone; Clinical Trials as Topic; Double-Blind Method;

1979
Pirenzepine in the treatment of benign gastroduodenal diseases. A double-blind controlled clinical trial.
    Scandinavian journal of gastroenterology. Supplement, 1979, Volume: 57

    Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Benzodiazepinones; Clinical Trials as Topic; Double-Blin

1979
Pirenzepine (LS 519) in severe duodenal ulcer and in gastric ulcer. A double-blind clinical trial.
    Scandinavian journal of gastroenterology. Supplement, 1979, Volume: 57

    Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Benzodiazepinones; Carbenoxolone; Clinical Trials as Top

1979
Pirenzepine in the treatment of gastric ulcer. A double-blind short-term clinical trial.
    Scandinavian journal of gastroenterology. Supplement, 1979, Volume: 57

    Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Benzodiazepinones; Clinical Trials as Topic; Double-Blin

1979
Effect of drug therapy on the relapse of peptic ulcers. 1st communication: the effect of acute therapy.
    Arzneimittel-Forschung, 1992, Volume: 42, Issue:8

    Topics: Cimetidine; Double-Blind Method; Humans; Peptic Ulcer; Pirenzepine; Recurrence; Stomach Ulcer

1992
[Comparison of the M1-blocker with the H2-blocker regarding their effects on gastric pH and viscosity under general anesthesia].
    Masui. The Japanese journal of anesthesiology, 1991, Volume: 40, Issue:1

    Topics: Adult; Anesthesia, General; Female; Gastric Juice; Humans; Hydrogen-Ion Concentration; Male; Middle

1991
Enprostil, a prostaglandin E2 analogue, in the treatment of gastric ulcer--a multicentre comparison with pirenzepine.
    The British journal of clinical practice, 1990, Volume: 44, Issue:2

    Topics: Adolescent; Adult; Aged; Double-Blind Method; Enprostil; Female; Humans; Male; Middle Aged; Multicen

1990
[3 mg telenzepine nocte in the treatment of benign stomach ulcer disease: a double-blind comparative study with 300 mg ranitidine nocte].
    Zeitschrift fur Gastroenterologie, 1990, Volume: 28, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Double-Blind Method; Drug Administration Schedule; Femal

1990
The intragastric milieu during gastric ulcer treatment with pirenzepine 50 mg b.i.d. or cimetidine 400 mg b.i.d.
    Zeitschrift fur Gastroenterologie, 1988, Volume: 26, Issue:11

    Topics: Adult; Aged; Bacteria; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Female; Fungi; Gas

1988
[Report of experience with stomach-protective therapy in high-dosage corticosteroid treatment of patients with brain tumors].
    Wiener medizinische Wochenschrift (1946), 1988, Mar-15, Volume: 138, Issue:5

    Topics: Administration, Oral; Anti-Ulcer Agents; Brain Edema; Brain Neoplasms; Dexamethasone; Dose-Response

1988
Gastric ulcer: a double-blind comparison of 100 mg pirenzepine plus antacid versus 800 mg cimetidine plus antacid.
    Scandinavian journal of gastroenterology, 1986, Volume: 21, Issue:7

    Topics: Antacids; Anti-Ulcer Agents; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Drug Adminis

1986
Use of antisecretory drugs for gastroprotection during antiblastic chemotherapy.
    Drugs under experimental and clinical research, 1985, Volume: 11, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Benzodiazepinones; Cyclophosphamide; Do

1985
Comparison of pirenzepine and carbenoxolone in the treatment of chronic gastric ulcer. A double-blind endoscopic trial.
    Hepato-gastroenterology, 1985, Volume: 32, Issue:6

    Topics: Anti-Ulcer Agents; Benzodiazepinones; Carbenoxolone; Chronic Disease; Clinical Trials as Topic; Doub

1985
[Comparative treatment of gastric ulcer with pirenzepin, cimetidine and placebo].
    Revista medica de Chile, 1985, Volume: 113, Issue:6

    Topics: Adult; Aged; Anti-Ulcer Agents; Benzodiazepinones; Cimetidine; Clinical Trials as Topic; Double-Blin

1985

Other Studies

47 other studies available for pirenzepine and Gastric Ulcer

ArticleYear
[Cytoprotective properties of pirenzepine, PGE2 and cimetidine in the rat].
    Bollettino chimico farmaceutico, 1981, Volume: 120, Issue:11

    Topics: Animals; Benzodiazepinones; Cimetidine; Dinoprostone; Female; Gastric Mucosa; Guanidines; Histamine

1981
Gastric cytoprotection by pirenzepine: role of endogenous catecholamines.
    International journal of tissue reactions, 1984, Volume: 6, Issue:2

    Topics: Animals; Anti-Ulcer Agents; Benzodiazepinones; Ethanol; Gastric Mucosa; Male; Norepinephrine; Pirenz

1984
[Use of gastrozepin in erosive-ulcerative diseases of the stomach and duodenum].
    Klinicheskaia meditsina, 1984, Volume: 62, Issue:7

    Topics: Anti-Ulcer Agents; Benzodiazepinones; Duodenal Ulcer; Female; Humans; Male; Pirenzepine; Stomach Ulc

1984
Gastric cytoprotection by pirenzepine is not mediated by catecholamines.
    Acta physiologica Hungarica, 1984, Volume: 64, Issue:3-4

    Topics: Animals; Anti-Ulcer Agents; Atropine; Benzodiazepinones; Disease Models, Animal; Gastric Mucosa; Mal

1984
Pharmacology: pirenzepine.
    Nursing mirror, 1983, Jun-15, Volume: 156, Issue:24

    Topics: Benzodiazepinones; Humans; Pirenzepine; Stomach Ulcer

1983
Further evidences on gastric cytoprotection exerted by pirenzepine.
    Pharmacological research communications, 1984, Volume: 16, Issue:7

    Topics: Animals; Anti-Ulcer Agents; Benzodiazepinones; Dinoprostone; Ethanol; Gastric Mucosa; Indomethacin;

1984
[Combined effect of FM-100 and several anti-ulcer agents on ulcer induced by ligation of the pylorus in rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1983, Volume: 82, Issue:1

    Topics: Aluminum; Animals; Anti-Ulcer Agents; Benzodiazepinones; Cimetidine; Drug Therapy, Combination; Gast

1983
[Pathogenesis, diagnosis and therapy of ulcer disease. Therapy. 3: Pharmacologic basis and therapy with pirenzepine].
    Die Medizinische Welt, 1983, Dec-02, Volume: 34, Issue:48

    Topics: Acetylcholine; Animals; Benzodiazepinones; Gastric Acid; Gastric Mucosa; Gastrins; Histamine; Humans

1983
[Effects of pirenzepin on the course of acute gastric stress lesions (author's transl)].
    Chirurgisches Forum fur experimentelle und klinische Forschung, 1980

    Topics: Benzodiazepinones; Double-Blind Method; Humans; Peptic Ulcer Hemorrhage; Piperazines; Pirenzepine; S

1980
Inhibition of gastric mucosa carbonic anhydrase by pirenzepine in patients with gastroduodenal ulcers.
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:3

    Topics: Animals; Benzodiazepinones; Carbonic Anhydrase Inhibitors; Cattle; Duodenal Ulcer; Gastric Mucosa; H

1981
Inhibition of gastrin secretion by pirenzepine (LS 519) in treatment of gastric ulcer.
    Scandinavian journal of gastroenterology, 1981, Volume: 16, Issue:2

    Topics: Adult; Aged; Anti-Ulcer Agents; Benzodiazepinones; Depression, Chemical; Female; Gastrins; Humans; M

1981
[Treatment of stomach ulcer (review)].
    Zeitschrift fur arztliche Fortbildung, 1982, Aug-15, Volume: 76, Issue:16

    Topics: Aluminum; Antacids; Benzodiazepinones; Bismuth; Carbenoxolone; Cimetidine; Feeding Behavior; Gastrec

1982
[Experience in the use of gastrotsepin in the treatment of stomach and duodenal ulcer].
    Klinicheskaia meditsina, 1995, Volume: 73, Issue:2

    Topics: Adolescent; Adult; Duodenal Ulcer; Evaluation Studies as Topic; Female; Humans; Male; Middle Aged; P

1995
[Gastrotsepin in the therapy and prevention of peptic ulcer exacerbations associated with Helicobacter pylori bacteriosis].
    Klinicheskaia meditsina, 1995, Volume: 73, Issue:1

    Topics: Drug Evaluation; Drug Therapy, Combination; Duodenal Ulcer; Helicobacter Infections; Helicobacter py

1995
Pharmacological profile of gastric mucosal protection by marmin and nobiletin from a traditional herbal medicine, Aurantii fructus immaturus.
    Japanese journal of pharmacology, 1994, Volume: 66, Issue:1

    Topics: Acetylcholine; Animals; Anti-Ulcer Agents; Coumarins; Drugs, Chinese Herbal; Electric Stimulation; F

1994
Effects of KW-5805, a new antiulcer agent, on experimental gastric and duodenal ulcers, gastric mucosal lesions by necrotizing agents and gastric acid secretion.
    Japanese journal of pharmacology, 1994, Volume: 65, Issue:4

    Topics: Animals; Anti-Ulcer Agents; Benzoxepins; Cimetidine; Depression, Chemical; Duodenal Ulcer; Ethanol;

1994
[New data on clinical response to therapeutic effects of gastrozepin].
    Klinicheskaia meditsina, 1996, Volume: 74, Issue:3

    Topics: Anti-Ulcer Agents; Duodenal Ulcer; Evaluation Studies as Topic; Humans; Peptic Ulcer; Pirenzepine; S

1996
Autonomic regulation of gastric ulcerogenesis after cervical cord transection in the rat.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 1998, Volume: 5, Issue:3

    Topics: Analysis of Variance; Animals; Anti-Ulcer Agents; Ephedrine; Evaluation Studies as Topic; Male; Musc

1998
[The gastric mucigenous function in the treatment of patients with ulcer with various antisecretory preparations].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2002, Issue:2

    Topics: Adult; Anti-Ulcer Agents; Duodenal Ulcer; Enzyme Inhibitors; Famotidine; Female; Gastric Acidity Det

2002
Effects of the M1 muscarinic receptor antagonist pirenzepine on gastric mucus glycoprotein in rats with or without ethanol-induced gastric damage.
    Scandinavian journal of gastroenterology, 1992, Volume: 27, Issue:9

    Topics: Animals; Carbohydrates; Ethanol; Gastric Mucosa; Glycoproteins; Male; Mucins; Muscarinic Antagonists

1992
[Comparison of the inhibitory effects of a psychostimulant of the sydnonimine series on the development of stress and ethanol induced lesions in the rat gastric mucosa].
    Biulleten' eksperimental'noi biologii i meditsiny, 1991, Volume: 112, Issue:7

    Topics: Animals; Antidepressive Agents; Atropine; Cold Temperature; Ethanol; Gastric Mucosa; Immobilization;

1991
Effects of pirenzepine on acute mucosal erosions, gastric acid and mucosal blood flow in the spinal rat stomach.
    Digestion, 1991, Volume: 49, Issue:4

    Topics: Animals; Antacids; Gastric Acid; Gastric Mucosa; Male; Pirenzepine; Rats; Rats, Inbred Strains; Regi

1991
BAY P 1455, a thiazolylaminobenzimidazole derivative with gastroprotective properties in the rat.
    European journal of pharmacology, 1991, Mar-26, Volume: 195, Issue:2

    Topics: Adrenalectomy; Animals; Anti-Ulcer Agents; Benzimidazoles; Cimetidine; Corticosterone; Cysteamine; D

1991
Controlling gastric pH: the impact of newer agents on the critically ill patient.
    DICP : the annals of pharmacotherapy, 1990, Volume: 24, Issue:11 Suppl

    Topics: Alprostadil; Anti-Ulcer Agents; Critical Care; Gastric Acid; Histamine H2 Antagonists; Humans; Hydro

1990
Direct comparison between the ulcer-healing effects of two H(+)-K(+)-ATPase inhibitors, one M1-selective antimuscarinic and one H2 receptor antagonist in the rat.
    Pharmacology, 1990, Volume: 41, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Triphosphatases; Animals; Anti-Ulcer Agents; Benz

1990
Studies on the mechanism for the gastric mucosal protection by famotidine in rats.
    Japanese journal of pharmacology, 1991, Volume: 55, Issue:2

    Topics: Animals; Anti-Ulcer Agents; Cimetidine; Famotidine; Gastric Mucosa; Male; Pirenzepine; Rats; Rats, I

1991
[The effects of pirenzepine on regenerating parietal cells].
    Revista espanola de enfermedades digestivas, 1990, Volume: 78, Issue:3

    Topics: Animals; Cytoplasm; Dose-Response Relationship, Drug; Parietal Cells, Gastric; Pirenzepine; Rats; Ra

1990
[Antiulcer treatment with Biotidin and Gastrozepin and its effect on the occupational fitness of drivers and machinery operators].
    Vutreshni bolesti, 1990, Volume: 29, Issue:3

    Topics: Adult; Automobile Driving; Bulgaria; Duodenal Ulcer; Engineering; Humans; Middle Aged; Physical Fitn

1990
[Mucosa protection--an assessable value? An experimental study in rats].
    Gastroenterologisches Journal : Organ der Gesellschaft fur Gastroenterologie der DDR, 1990, Volume: 49, Issue:4

    Topics: Animals; Cimetidine; Female; Gastric Acidity Determination; Gastric Mucosa; Pirenzepine; Rats; Rats,

1990
A simple method for estimation of gastric mucus and effects of antiulcerogenic agents on the decrease in mucus during water-immersion stress in rats.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:8

    Topics: Alcian Blue; Animals; Anti-Ulcer Agents; Atropine; Bombesin; Gastric Mucosa; Immersion; Irritants; M

1986
Quantitation by computerized visual image analysis of gastric mucosal lesions induced in mice and rats by non-steroidal anti-inflammatory drugs.
    Acta physiologica Hungarica, 1989, Volume: 73, Issue:2-3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bethanechol; Bethanechol Compounds; Dinoprostone;

1989
Circadian rhythms of food intake in gastroduodenally-ulcerated rats: effects of three anti-ulcer drugs.
    Chronobiology international, 1989, Volume: 6, Issue:4

    Topics: Animals; Anti-Ulcer Agents; Circadian Rhythm; Duodenal Ulcer; Eating; Female; Indomethacin; Male; Pi

1989
[Prevention of stress ulcer in intensive care patients].
    Wiener medizinische Wochenschrift (1946), 1986, Nov-30, Volume: 136, Issue:21-22

    Topics: Alprostadil; Antacids; Critical Care; Drug Therapy, Combination; Enteral Nutrition; Histamine H2 Ant

1986
[Cytoprotective activity of tiquizium bromide (HSR-902) and its mechanism].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1987, Volume: 90, Issue:5

    Topics: Animals; Bicarbonates; Ganglionic Blockers; Gastric Mucosa; Male; Pirenzepine; Quinolizines; Rats; R

1987
[Antiulcer effects of pirenzepine in rats].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1988, Volume: 9, Issue:5

    Topics: Animals; Cats; Duodenal Ulcer; Female; Gastric Acid; Gastric Juice; Gastrins; Hexosamines; Male; Pep

1988
Effects of antisecretory drugs on mucosal erosions induced by intragastric distension in rats: a comparative study.
    Methods and findings in experimental and clinical pharmacology, 1988, Volume: 10, Issue:1

    Topics: Animals; Carbenoxolone; Cimetidine; Dinoprostone; Gastric Mucosa; In Vitro Techniques; Male; Pirenze

1988
[Action of the drug pirenzepine on regenerating parietal cells. Morphological and quantitative study].
    Revista espanola de las enfermedades del aparato digestivo, 1988, Volume: 74, Issue:3

    Topics: Animals; Gastric Acid; Male; Parietal Cells, Gastric; Pirenzepine; Rats; Rats, Inbred Strains; Regen

1988
Comparison of the gastric antisecretory and antiulcer potencies of telenzepine, pirenzepine, ranitidine and cimetidine in the rat.
    Digestion, 1988, Volume: 40, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Cimetidine; Female; Gastric Acid; Parasympatholytics; Pirenzepine; Ranit

1988
Effects of antimuscarinic agents and prostaglandin E2 on the gastric mucosal lesions induced by necrotizing agents and water-immersion stress in rats.
    Japanese journal of pharmacology, 1986, Volume: 41, Issue:3

    Topics: Animals; Anti-Ulcer Agents; Atropine; Cimetidine; Dinoprostone; Male; Parasympatholytics; Pirenzepin

1986
Effect of pirenzepine and PGE2 on taurocholic acid-induced gastric lesions.
    Pharmacological research communications, 1986, Volume: 18, Issue:8

    Topics: Animals; Anti-Ulcer Agents; Dinoprostone; Male; Pirenzepine; Prostaglandins E; Rats; Rats, Inbred St

1986
Cytoprotective effect of pirenzepine and palm wine on rats gastric mucosa.
    Scandinavian journal of gastroenterology. Supplement, 1986, Volume: 124

    Topics: Animals; Ethanol; Female; Gastric Mucosa; Male; Pirenzepine; Rats; Rats, Inbred Strains; Stomach Ulc

1986
The role of phospholipase in the genesis of gastric ulcers in rats.
    Scandinavian journal of gastroenterology, 1987, Volume: 22, Issue:5

    Topics: Animals; Gastric Juice; Gastric Mucosa; Male; Phospholipases; Pirenzepine; Prostaglandins; Rats; Rat

1987
Pharmacokinetics of pirenzepine in patients with gastric or duodenal ulcers.
    Arzneimittel-Forschung, 1987, Volume: 37, Issue:8

    Topics: Administration, Oral; Adult; Duodenal Ulcer; Female; Half-Life; Humans; Male; Middle Aged; Pirenzepi

1987
[Do anticholinergic drugs still have significance in the therapy of ulcer?].
    Leber, Magen, Darm, 1986, Volume: 16, Issue:6

    Topics: Atropine; Cimetidine; Drug Therapy, Combination; Duodenal Ulcer; Gastric Acid; Humans; Parasympathol

1986
Effects of atropine and pirenzepine on healing of gastric ulcer induced by mucosal excision in rats.
    Clinical therapeutics, 1985, Volume: 7, Issue:3

    Topics: Animals; Atropine; Benzodiazepinones; Electric Stimulation; Gastric Acid; Gastric Mucosa; Male; Para

1985
Pirenzepine and gastroduodenal ulcers.
    The New Zealand medical journal, 1985, Jan-23, Volume: 98, Issue:771

    Topics: Benzodiazepinones; Duodenal Ulcer; Humans; Pirenzepine; Stomach Ulcer

1985
Gastric cytoprotection by pirenzepine in rats: evaluating method for cytoprotective activity by antisecretory agents.
    Japanese journal of pharmacology, 1985, Volume: 38, Issue:4

    Topics: Animals; Anti-Ulcer Agents; Atropine; Benzodiazepinones; Buffers; Cimetidine; Dinoprostone; Ethanol;

1985