pirenzepine has been researched along with Erosive Duodenitis in 9 studies
Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effectiveness of pirenzepine in the treatment of duodenal ulcer was assessed in a double-blind clinical trial in comparison with placebo." | 9.04 | A double-blind, short-term clinical trial of pirenzepine in duodenal ulcer. ( Morelli, A; Narducci, F; Pelli, MA; Spadacini, A, 1979) |
| "Pirenzepine (PRZ, 75 mg/day for 10 days followed by 50 mg/day for 20 days) was compared with placebo (PL) in the treatment of endoscopically confirmed active gastroduodenitis or duodenal ulcer and with carbenoxolone (CB, 300 mg/day followed by 200 mg/day) in the treatment of gastric ulcer in a 30-day double-blind clinical trial." | 5.04 | Pirenzepine in the treatment of benign gastroduodenal diseases. A double-blind controlled clinical trial. ( Cifani, G; D'Anchino, M; Di Tommaso, B; Gasbarrini, G; Giorgi-Conciato, M; Pesa, O; Sollecito, A, 1979) |
| "The effectiveness of pirenzepine in the treatment of duodenal ulcer was assessed in a double-blind clinical trial in comparison with placebo." | 5.04 | A double-blind, short-term clinical trial of pirenzepine in duodenal ulcer. ( Morelli, A; Narducci, F; Pelli, MA; Spadacini, A, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lagarde, SP | 1 |
| Spiro, HM | 1 |
| Giorgi-Conciato, M | 2 |
| Daniotti, S | 2 |
| Ferrari, PA | 1 |
| Gaetani, M | 1 |
| Petrin, G | 1 |
| Sala, P | 1 |
| Valentini, P | 2 |
| Giaccari, S | 1 |
| Tronci, S | 1 |
| De Maria, E | 1 |
| Chirletti, P | 1 |
| Colobraro, P | 1 |
| Romano, R | 1 |
| Barzi, A | 1 |
| Mangialardi, N | 1 |
| Bertoldi, I | 1 |
| Cirenei, A | 1 |
| Dítĕ, P | 1 |
| Hulek, P | 1 |
| Trojanová, J | 1 |
| Skaunic, V | 1 |
| Gasbarrini, G | 1 |
| D'Anchino, M | 1 |
| Di Tommaso, B | 1 |
| Pesa, O | 1 |
| Sollecito, A | 1 |
| Cifani, G | 1 |
| Morelli, A | 1 |
| Narducci, F | 1 |
| Pelli, MA | 1 |
| Spadacini, A | 1 |
| Guslandi, M | 2 |
| Ballarin, E | 1 |
| Basilico, M | 1 |
| Tittobello, A | 1 |
2 reviews available for pirenzepine and Erosive Duodenitis
| Article | Year |
|---|---|
Non-ulcer dyspepsia.
Topics: Antacids; Benzodiazepinones; Diet; Duodenitis; Dyspepsia; Gastric Acid; Gastritis; Gastrointestinal | 1984 |
Focus on duodenitis.
Topics: Cimetidine; Diagnosis, Differential; Duodenal Ulcer; Duodenitis; Endoscopy; Humans; Pirenzepine | 1986 |
4 trials available for pirenzepine and Erosive Duodenitis
| Article | Year |
|---|---|
Efficacy and safety of pirenzepine in peptic ulcer and in non ulcerous gastroduodenal diseases. A multicentre controlled clinical trial.
Topics: Adult; Benzodiazepinones; Carbenoxolone; Cimetidine; Clinical Trials as Topic; Duodenal Ulcer; Duode | 1982 |
Pirenzepine in the treatment of benign gastroduodenal diseases. A double-blind controlled clinical trial.
Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Benzodiazepinones; Clinical Trials as Topic; Double-Blin | 1979 |
A double-blind, short-term clinical trial of pirenzepine in duodenal ulcer.
Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Benzodiazepinones; Clinical Trials as Topic; Double-Blin | 1979 |
Pirenzepine in erosive duodenitis. A controlled clinical trial versus ranitidine.
Topics: Adult; Aged; Anti-Ulcer Agents; Benzodiazepinones; Chronic Disease; Clinical Trials as Topic; Double | 1985 |
3 other studies available for pirenzepine and Erosive Duodenitis
| Article | Year |
|---|---|
[Pirenzepin in the treatment of toxic gastroduodenitis in chronic alcoholics].
Topics: Alcoholism; Benzodiazepinones; Drug Evaluation; Duodenitis; Gastritis; Humans; Pirenzepine | 1984 |
[Pirenzepine parenterally administered in high doses in the treatment of upper digestive hemorrhage].
Topics: Adult; Aged; Benzodiazepinones; Duodenitis; Female; Gastritis; Gastrointestinal Hemorrhage; Humans; | 1984 |
[Pirenzepin in the treatment of duodenal bulbitis (author's transl)].
Topics: Adult; Anti-Ulcer Agents; Benzodiazepinones; Duodenitis; Female; Humans; Male; Middle Aged; Piperazi | 1982 |