Page last updated: 2024-11-02

pirenzepine and Electrocardiogram QT Prolonged

pirenzepine has been researched along with Electrocardiogram QT Prolonged in 7 studies

Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.

Research Excerpts

ExcerptRelevanceReference
"Results of these analyses suggest that olanzapine, as therapeutically administered to patients with schizophrenia and related psychoses, does not contribute to QTc prolongation resulting in potentially fatal ventricular arrhythmias."9.09Analysis of the QTc interval during olanzapine treatment of patients with schizophrenia and related psychosis. ( Beasley, CM; Berg, PH; Czekalla, J; Dellva, MA; Grundy, S, 2001)
"The pruritus was also based on chronic, self-induced skin lesions due to aggressive disinfection and tearing out of body hair."5.32[A case of delusional parasitosis in severe heart failure. Olanzapine within the framework of a multimodal therapy]. ( Freudenmann, RW, 2003)
"Results of these analyses suggest that olanzapine, as therapeutically administered to patients with schizophrenia and related psychoses, does not contribute to QTc prolongation resulting in potentially fatal ventricular arrhythmias."5.09Analysis of the QTc interval during olanzapine treatment of patients with schizophrenia and related psychosis. ( Beasley, CM; Berg, PH; Czekalla, J; Dellva, MA; Grundy, S, 2001)
" The present article reviews important differences among antipsychotic drugs in the potential for, and occurrence of, serious adverse cardiac outcomes and suggests that olanzapine, as therapeutically administered to patients with schizophrenia and related psychoses, does not contribute significantly to a QTc prolongation that could result in potentially fatal ventricular arrhythmias."4.81Cardiac safety parameters of olanzapine: comparison with other atypical and typical antipsychotics. ( Beasley, CM; Czekalla, J; Kollack-Walker, S, 2001)
"The pruritus was also based on chronic, self-induced skin lesions due to aggressive disinfection and tearing out of body hair."1.32[A case of delusional parasitosis in severe heart failure. Olanzapine within the framework of a multimodal therapy]. ( Freudenmann, RW, 2003)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gupta, N1
Malhotra, P1
Freudenmann, RW1
Gurovich, I1
Vempaty, A1
Lippmann, S1
Zareba, W1
Lin, DA1
Czekalla, J2
Kollack-Walker, S1
Beasley, CM2
Dellva, MA1
Berg, PH1
Grundy, S1
Wilton, LV1
Heeley, EL1
Pickering, RM1
Shakir, SA1

Reviews

2 reviews available for pirenzepine and Electrocardiogram QT Prolonged

ArticleYear
Antipsychotic drugs and QT interval prolongation.
    The Psychiatric quarterly, 2003,Fall, Volume: 74, Issue:3

    Topics: Age Factors; Algorithms; Antipsychotic Agents; Benzodiazepines; Death, Sudden, Cardiac; Dopamine Ant

2003
Cardiac safety parameters of olanzapine: comparison with other atypical and typical antipsychotics.
    The Journal of clinical psychiatry, 2001, Volume: 62 Suppl 2

    Topics: Acute Disease; Antipsychotic Agents; Arrhythmias, Cardiac; Benzodiazepines; Death, Sudden; Female; H

2001

Trials

1 trial available for pirenzepine and Electrocardiogram QT Prolonged

ArticleYear
Analysis of the QTc interval during olanzapine treatment of patients with schizophrenia and related psychosis.
    The Journal of clinical psychiatry, 2001, Volume: 62, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Antipsychotic Agent

2001

Other Studies

4 other studies available for pirenzepine and Electrocardiogram QT Prolonged

ArticleYear
Olanzapine: a proarrhythmic drug?
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2002, Volume: 47, Issue:7

    Topics: Aged; Antiparkinson Agents; Antipsychotic Agents; Benzodiazepines; Carbidopa; Electrocardiography; F

2002
[A case of delusional parasitosis in severe heart failure. Olanzapine within the framework of a multimodal therapy].
    Der Nervenarzt, 2003, Volume: 74, Issue:7

    Topics: Aged; Antipsychotic Agents; Benzodiazepines; Comorbidity; Delusions; Dementia, Vascular; Drug Intera

2003
QTc prolongation: chlorpromazine and high-dosage olanzapine.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2003, Volume: 48, Issue:5

    Topics: Aged; Antipsychotic Agents; Benzodiazepines; Dose-Response Relationship, Drug; Female; Health Status

2003
Comparative study of mortality rates and cardiac dysrhythmias in post-marketing surveillance studies of sertindole and two other atypical antipsychotic drugs, risperidone and olanzapine.
    Journal of psychopharmacology (Oxford, England), 2001, Volume: 15, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Arrhythmias, Cardiac; Benzodiazepines; Cohort

2001