pirenzepine has been researched along with Disorders of Excessive Somnolence in 2 studies
Pirenzepine: An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.
Disorders of Excessive Somnolence: Disorders characterized by hypersomnolence during normal waking hours that may impair cognitive functioning. Subtypes include primary hypersomnia disorders (e.g., IDIOPATHIC HYPERSOMNOLENCE; NARCOLEPSY; and KLEINE-LEVIN SYNDROME) and secondary hypersomnia disorders where excessive somnolence can be attributed to a known cause (e.g., drug affect, MENTAL DISORDERS, and SLEEP APNEA SYNDROME). (From J Neurol Sci 1998 Jan 8;153(2):192-202; Thorpy, Principles and Practice of Sleep Medicine, 2nd ed, p320)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to estimate the long-term effectiveness of olanzapine as adjunctive therapy in patients with bipolar disorder who exhibited an inadequate response to mood stabilizers." | 9.09 | Olanzapine as long-term adjunctive therapy in treatment-resistant bipolar disorder. ( Benabarre, A; Colom, F; Corbella, B; Gastó, C; Gilaberte, I; Martínez-Arán, A; Reinares, M; Tohen, M; Vieta, E, 2001) |
| "Open-label olanzapine treatment was efficacious and well tolerated in the treatment of acute mania in youths with bipolar disorder." | 9.09 | A prospective open-label treatment trial of olanzapine monotherapy in children and adolescents with bipolar disorder. ( Biederman, J; Feldman, PD; Frazier, JA; Garfield, SB; Gonzalez-Heydrich, J; Jacobs, TG; Kim, GS; Nowlin, ZM; Rater, MA; Risser, RC; Sohma, M; Tarazi, RA; Tohen, M; Toma, V, 2001) |
| "The aim of this study was to estimate the long-term effectiveness of olanzapine as adjunctive therapy in patients with bipolar disorder who exhibited an inadequate response to mood stabilizers." | 5.09 | Olanzapine as long-term adjunctive therapy in treatment-resistant bipolar disorder. ( Benabarre, A; Colom, F; Corbella, B; Gastó, C; Gilaberte, I; Martínez-Arán, A; Reinares, M; Tohen, M; Vieta, E, 2001) |
| "Open-label olanzapine treatment was efficacious and well tolerated in the treatment of acute mania in youths with bipolar disorder." | 5.09 | A prospective open-label treatment trial of olanzapine monotherapy in children and adolescents with bipolar disorder. ( Biederman, J; Feldman, PD; Frazier, JA; Garfield, SB; Gonzalez-Heydrich, J; Jacobs, TG; Kim, GS; Nowlin, ZM; Rater, MA; Risser, RC; Sohma, M; Tarazi, RA; Tohen, M; Toma, V, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vieta, E | 1 |
| Reinares, M | 1 |
| Corbella, B | 1 |
| Benabarre, A | 1 |
| Gilaberte, I | 1 |
| Colom, F | 1 |
| Martínez-Arán, A | 1 |
| Gastó, C | 1 |
| Tohen, M | 2 |
| Frazier, JA | 1 |
| Biederman, J | 1 |
| Feldman, PD | 1 |
| Jacobs, TG | 1 |
| Toma, V | 1 |
| Rater, MA | 1 |
| Tarazi, RA | 1 |
| Kim, GS | 1 |
| Garfield, SB | 1 |
| Sohma, M | 1 |
| Gonzalez-Heydrich, J | 1 |
| Risser, RC | 1 |
| Nowlin, ZM | 1 |
2 trials available for pirenzepine and Disorders of Excessive Somnolence
| Article | Year |
|---|---|
Olanzapine as long-term adjunctive therapy in treatment-resistant bipolar disorder.
Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Disorders of Excessive Somnolence; D | 2001 |
A prospective open-label treatment trial of olanzapine monotherapy in children and adolescents with bipolar disorder.
Topics: Abdominal Pain; Adolescent; Antipsychotic Agents; Appetite; Benzodiazepines; Bipolar Disorder; Brief | 2001 |